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•From the Ancient Greek onkos (ὄγκος), meaning, mass,
or tumor
•And the suffix -logy (-λογία), meaning "study of")
WHAT IS THE
CANCER ?
 Canser is disease
characterized by cells that
 grow and divide without
respect to normol control
 invade and destroy adjacent
tissues
men women
lung cancer
stomach cancer
prostate cancer
breast cancer
stomach cancer
uterus
lung
rectum and colon
skin
 Oncological diseases take the third place after
diseases of the cardiovascular system and injuries.
 More than 6 million new cases are registered
annually.
The most frequent location of the tumour
• Mortality is 20% of the total mortality rate. 5-
year survival rate – 40%
 Tumor malignant –
20%
 Tumor benign –
80%
Cancer
Adults – 60%
Children – 20%
Sarcoma
Adults – 40%
Children – 80%
 Cancer is a malignant neoplasm of epithelial
tissue.
 Sarcoma - malignant neoplasm made of
connective tissue.
 Squamous cell cancer – tumor from flat
epithelium
 Adenocarcinoma is a tumor of glandular
epithelium
Malignant
 Atypia (unusual) and
polymorphism
(diversity) of cells
 rapid cell growth
 MTS
 tend to recur
 Intoxication and
cachexia
Benign
 -
 grows slowly
 No MTS
 No recurrence
 no effect on the general
condition
TYPE TUMOR DISEASE
TISSUE FROM WHICH THE TUMOR
COMES
1. Carcinoma or
cancer
2. Melanoma
3. Sarcoma
1. Epithelial tissue (cancer
prostate, lung, breast, colon)
2. melanocytes (skin melanoma,
retina, mucous membranes)
3. Connective tissue, bone, and
muscle (mesenchyme) (Soft
tissue sarcoma, uterine
sarcoma, honrosarkoma,
osteosarcoma, fibrosarcoma
TYPE TUMOR DISEASE
TISSUE FROM WHICH
THE TUMOR COMES
4. Leukosis
5. Lymphoma
6. Teratoma
4. Bone marrow stem cells
5. Lymphatic tissue (Hodgkin's
lymphoma, Hodgkin's
disease, lymphoma
nehodzhinskie)
6. The germ cells (teratoma in
the ovaries, testes, in the
sacrococcygeal region in the
brain)
TYPE TUMOR DISEASE TISSUE FROM WHICH
THE TUMOR COMES
7. Glioma
8. Choriocarcinoma
7. Glial cells (glioma brain)
8. Placental tissue
(choriocarcinoma of the
uterus, ovaries, fallopian
tubes, abdominal ectopic
choriocarcinoma)
 Cancer affects 1 in 3
of us in our lifetime.
 Over 70% of cancers
happen to people who
are over the age of 50
 Cancer can affect
people of all ages
 Cancer causes about
13% of all death
 Chemical Carcinogens
 Substances that cause
DNA mutaions are known
as mutagens
 Tobacco smoking is
associated with lung
cancer
 Alcohol is associated with
stomach, liver, mouth
cancer
CAUSES;
Tobacco(25-
30%)
Diet and
Obesity(30-35%)
Infections(15-20%) Radiation
Stress
Lack of phisical
activity
Environmental
pollution
Local Symptoms:
 Unusual lumps or tumor
 Hemorrhage (bleeding)
 Pain and ulceration
 Compression of surrounding
Enlarged lymph nodes
Cough, especially blood in cough
Bone pain, fracture of affected bones
Systematic Symptoms:
Weight loss
Poor appetite and severe weight loss
Excessive sweating especially at night
Anemia
MTS
 As a result of tumor growth, individual cells
can break off and enter into the blood, lymph
and other tissues.
Ways of MTS:
1. lymphogenous
2. hematogenous
3. implantation
COMMON CANCER TYPES
1.Colorectal Cancer
•family history
•low fiber diet
•history of rectal polyps
2.Skin Cancer
•Excessive exposure
•Fair complexion
•Work with coal, tar
3.Stomach Cancer
•Family history
•Diet heavy in smoked, picked or
salted foods
4.Esophageal Cancer
•heavy alcohol comsumption
•smoking
5.Prostate Cancer
•increasing of age
•family history
•diet high in animal fat
6.Lung Cancer
•cigarette smoking
•asbestos, arsenic and radon exposure
•secondhand smoke
 unusual lumps or swelling (tumor),
 hemorrhage (bleeding),
 pain and/or ulceration.
 Compression of surrounding tissues may
cause symptoms such as jaundice.
 Enlarged lymph nodes,
 Cough, especially blood in cough,
 enlarged liver,
 bone pain, fracture of affected bones.
 Although advanced cancer may cause pain,
it is often not the first symptom.
 weight loss,
 poor appetite and severe weight loss,
 excessive sweating especially at night,
 anemia
 Cancers are recognized either because-
 signs or symptoms appear,
 screening.
 Biopsy
 A cancer may be suspected for a variety of
reasons, but the definitive diagnosis of most
malignancies must be confirmed by
histological examination of the cancerous
cells by a pathologist.
.
 These commonly include
blood tests, X-rays, CT
scans and a camera
test(endoscopy).
 Chest x-ray showing lung
cancer in the left lung.
TREATMENT
Cancer can be treated by
 Surgery
 Radiation therapy
 Drug therapy:
 Chemotherapy
 Immunotherapy
 Hormonal therapy
 Ablation - it is different measures, it’s aim is to destroy
existing tumor: during surgery take away all the tumor
elements within the healthy tissue. any tumor cell should
not stay in place of operations.
 Antiablation - a set of preventive measures, it’s aim is
to prevent the development of metastases.
For example: prevention of tumor elements entering into
the intersection during surgery blood and lymph vessels
as well as preoperative and postoperative radiation
effect that reduces the viability of tumor cells.
 Radical - is cure of the patient, removal of
the tumor and MTS
 Palliative - is reduction of tumor and delay
its growth. Increase life expectancy of the
patient.
 Symptomatic- is without treatment of
primary tumor (removal of symptoms of
disease associated with tumor.
 For example: anastomosis in stomach
cancer
 I A gr. – patients with pretumor disease
 I B gr. – patients with suspected cancer
 II gr. – cancer patients, needed in radical
therapy
 III gr. – cancer patients after radical therapy
(observation)
 IV gr. – cancer patients (palliative and
symptomatic therapy)
 Cancer has a reputation for being a deadly
disease.
 With modern treatment the prognosis is
improving and actually much better than
heart attack or stroke in some cases.
 Modifiable ("lifestyle") risk factors
 Alcohol consumption (associated with
increased risk of oral, esophageal, breast,
and other cancers),
 smoking
 physical inactivity (associated with
increased risk of colon, breast, and
possibly other cancers),
 overweight (associated with colon, breast,
endometrial, and possibly other cancers).
1. What is the oncology?
2. What types (kinds) of cancer?
3. What are the different between malignant
and benign tumors?
4. What are the symptoms?
5. What is the MTS?
6. What is symptoms MTS?
7. What are causes of cancer?
8. What are the treatment for cancer?

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lech. introduction — копия 3.ppt

  • 1. •From the Ancient Greek onkos (ὄγκος), meaning, mass, or tumor •And the suffix -logy (-λογία), meaning "study of")
  • 2.
  • 4.  Canser is disease characterized by cells that  grow and divide without respect to normol control  invade and destroy adjacent tissues
  • 5. men women lung cancer stomach cancer prostate cancer breast cancer stomach cancer uterus lung rectum and colon skin  Oncological diseases take the third place after diseases of the cardiovascular system and injuries.  More than 6 million new cases are registered annually. The most frequent location of the tumour • Mortality is 20% of the total mortality rate. 5- year survival rate – 40%
  • 6.  Tumor malignant – 20%  Tumor benign – 80% Cancer Adults – 60% Children – 20% Sarcoma Adults – 40% Children – 80%
  • 7.  Cancer is a malignant neoplasm of epithelial tissue.  Sarcoma - malignant neoplasm made of connective tissue.  Squamous cell cancer – tumor from flat epithelium  Adenocarcinoma is a tumor of glandular epithelium
  • 8. Malignant  Atypia (unusual) and polymorphism (diversity) of cells  rapid cell growth  MTS  tend to recur  Intoxication and cachexia Benign  -  grows slowly  No MTS  No recurrence  no effect on the general condition
  • 9. TYPE TUMOR DISEASE TISSUE FROM WHICH THE TUMOR COMES 1. Carcinoma or cancer 2. Melanoma 3. Sarcoma 1. Epithelial tissue (cancer prostate, lung, breast, colon) 2. melanocytes (skin melanoma, retina, mucous membranes) 3. Connective tissue, bone, and muscle (mesenchyme) (Soft tissue sarcoma, uterine sarcoma, honrosarkoma, osteosarcoma, fibrosarcoma
  • 10. TYPE TUMOR DISEASE TISSUE FROM WHICH THE TUMOR COMES 4. Leukosis 5. Lymphoma 6. Teratoma 4. Bone marrow stem cells 5. Lymphatic tissue (Hodgkin's lymphoma, Hodgkin's disease, lymphoma nehodzhinskie) 6. The germ cells (teratoma in the ovaries, testes, in the sacrococcygeal region in the brain)
  • 11. TYPE TUMOR DISEASE TISSUE FROM WHICH THE TUMOR COMES 7. Glioma 8. Choriocarcinoma 7. Glial cells (glioma brain) 8. Placental tissue (choriocarcinoma of the uterus, ovaries, fallopian tubes, abdominal ectopic choriocarcinoma)
  • 12.  Cancer affects 1 in 3 of us in our lifetime.  Over 70% of cancers happen to people who are over the age of 50  Cancer can affect people of all ages  Cancer causes about 13% of all death
  • 13.  Chemical Carcinogens  Substances that cause DNA mutaions are known as mutagens  Tobacco smoking is associated with lung cancer  Alcohol is associated with stomach, liver, mouth cancer
  • 15. Local Symptoms:  Unusual lumps or tumor  Hemorrhage (bleeding)  Pain and ulceration  Compression of surrounding
  • 16. Enlarged lymph nodes Cough, especially blood in cough Bone pain, fracture of affected bones Systematic Symptoms: Weight loss Poor appetite and severe weight loss Excessive sweating especially at night Anemia
  • 17. MTS  As a result of tumor growth, individual cells can break off and enter into the blood, lymph and other tissues. Ways of MTS: 1. lymphogenous 2. hematogenous 3. implantation
  • 18. COMMON CANCER TYPES 1.Colorectal Cancer •family history •low fiber diet •history of rectal polyps 2.Skin Cancer •Excessive exposure •Fair complexion •Work with coal, tar 3.Stomach Cancer •Family history •Diet heavy in smoked, picked or salted foods
  • 19. 4.Esophageal Cancer •heavy alcohol comsumption •smoking 5.Prostate Cancer •increasing of age •family history •diet high in animal fat 6.Lung Cancer •cigarette smoking •asbestos, arsenic and radon exposure •secondhand smoke
  • 20.  unusual lumps or swelling (tumor),  hemorrhage (bleeding),  pain and/or ulceration.  Compression of surrounding tissues may cause symptoms such as jaundice.
  • 21.  Enlarged lymph nodes,  Cough, especially blood in cough,  enlarged liver,  bone pain, fracture of affected bones.  Although advanced cancer may cause pain, it is often not the first symptom.
  • 22.  weight loss,  poor appetite and severe weight loss,  excessive sweating especially at night,  anemia
  • 23.  Cancers are recognized either because-  signs or symptoms appear,  screening.  Biopsy  A cancer may be suspected for a variety of reasons, but the definitive diagnosis of most malignancies must be confirmed by histological examination of the cancerous cells by a pathologist.
  • 24. .  These commonly include blood tests, X-rays, CT scans and a camera test(endoscopy).  Chest x-ray showing lung cancer in the left lung.
  • 25. TREATMENT Cancer can be treated by  Surgery  Radiation therapy  Drug therapy:  Chemotherapy  Immunotherapy  Hormonal therapy
  • 26.  Ablation - it is different measures, it’s aim is to destroy existing tumor: during surgery take away all the tumor elements within the healthy tissue. any tumor cell should not stay in place of operations.  Antiablation - a set of preventive measures, it’s aim is to prevent the development of metastases. For example: prevention of tumor elements entering into the intersection during surgery blood and lymph vessels as well as preoperative and postoperative radiation effect that reduces the viability of tumor cells.
  • 27.  Radical - is cure of the patient, removal of the tumor and MTS  Palliative - is reduction of tumor and delay its growth. Increase life expectancy of the patient.  Symptomatic- is without treatment of primary tumor (removal of symptoms of disease associated with tumor.  For example: anastomosis in stomach cancer
  • 28.  I A gr. – patients with pretumor disease  I B gr. – patients with suspected cancer  II gr. – cancer patients, needed in radical therapy  III gr. – cancer patients after radical therapy (observation)  IV gr. – cancer patients (palliative and symptomatic therapy)
  • 29.  Cancer has a reputation for being a deadly disease.  With modern treatment the prognosis is improving and actually much better than heart attack or stroke in some cases.
  • 30.  Modifiable ("lifestyle") risk factors  Alcohol consumption (associated with increased risk of oral, esophageal, breast, and other cancers),  smoking  physical inactivity (associated with increased risk of colon, breast, and possibly other cancers),  overweight (associated with colon, breast, endometrial, and possibly other cancers).
  • 31. 1. What is the oncology? 2. What types (kinds) of cancer? 3. What are the different between malignant and benign tumors? 4. What are the symptoms? 5. What is the MTS? 6. What is symptoms MTS? 7. What are causes of cancer? 8. What are the treatment for cancer?