This document discusses Kushta, a traditional herbo-mineral formulation used in Unani medicine. It provides background on traditional medicine practices in South Asia. Kushta is described as a finely powdered blend of minerals and herbal extracts prepared through a process of calcination. This results in nanoparticles that are easily absorbed and potent. The document outlines the historical origins and development of Unani medicine. It explains the preparation process for Kushta and some potential mechanisms of action. Some commonly used Kushta formulations are listed along with their herbal ingredients and medicinal uses. In summary, the document provides an overview of Kushta as a traditional herbo-mineral dosage form in Unani medicine, including its
Sandhāna Kalpana is an Alcoholic or Acidic Medicinal preparations of Ayurvedic Pharmaceuticals, It involves the process of fermentation where the 'dravadravya' (kwātha, swarasa or liquid preparation), 'madhura dravya' (jaggery, honey or sugar), 'praksepa dravya' (fine powders of medicinal drugs) and 'sandhäna dravya' (dhātaki puspa, madhuka puspa as fermentation initiators) are put together in an inert vessel (mud pot) and sealed for a specified time period to facilitate the process of fermentation Madhya (Alcoholic) and Shukti (Acedic) are the two basic types of this process
Very popular Ayurvedic oil preparation indicated in osteoarthritis, rheumatic arthritis, edema & movement restriction. Mainly helpful in relieving pain. it is mentioned in Sahasrayoga Book.
Sandhāna Kalpana is an Alcoholic or Acidic Medicinal preparations of Ayurvedic Pharmaceuticals, It involves the process of fermentation where the 'dravadravya' (kwātha, swarasa or liquid preparation), 'madhura dravya' (jaggery, honey or sugar), 'praksepa dravya' (fine powders of medicinal drugs) and 'sandhäna dravya' (dhātaki puspa, madhuka puspa as fermentation initiators) are put together in an inert vessel (mud pot) and sealed for a specified time period to facilitate the process of fermentation Madhya (Alcoholic) and Shukti (Acedic) are the two basic types of this process
Very popular Ayurvedic oil preparation indicated in osteoarthritis, rheumatic arthritis, edema & movement restriction. Mainly helpful in relieving pain. it is mentioned in Sahasrayoga Book.
Rasashastra is a branch of Ayurveda in which medicines of mineral origin are manufactured & used in various diseases.
Rasashastra medicines are classified Based on method of preparation.
Role of Ayurvedic drugs in KASA (COUGH)
Dr. Rajtilak Tiwari M.D. ( Kayachikitsa)
{Assistant Professor in Kayachikitsa dept. in Shivshakti lal sharma Ayurvedic College Ratlam (M.P.)}
Rasashastra is a branch of Ayurveda in which medicines of mineral origin are manufactured & used in various diseases.
Rasashastra medicines are classified Based on method of preparation.
Role of Ayurvedic drugs in KASA (COUGH)
Dr. Rajtilak Tiwari M.D. ( Kayachikitsa)
{Assistant Professor in Kayachikitsa dept. in Shivshakti lal sharma Ayurvedic College Ratlam (M.P.)}
Prakruty is a Sansakrit language word and means for Constitution of human body charesteristics and their recognition through sign and symptoms. This is very necessary when Ayurveda treatment is given. This is one of the basic fundamentals of Ayurvedic Medical science. How a physician will be able to detect the Prakruty, is dependent upon the signs of the body. In this slide show the reader will find the glimps of the different functions and signs to recognise the prakruty.
Psoriasis Ayurvedic Treatment Centre in Punjab, IndiaDr. Amit Dutta
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Pharamacaeutico Analytical Evaluation of Kaseesa Bhasmaijtsrd
Bhasmas are unique Ayurvedic preparations of metals minerals formulated with herbal extracts or juices and used for the treatment of a variety of ailments. Owing to their micro nano fineness, ease of administration and comparatively small dose, they have been known for their vast area of application and therapeutic value. Kaseesa FeSO4.7H2O is an iron containing used in the treatment of eye diseases, pruritis, leucoderma, dysurea, helminthiasis. diabetes The present study was conducted to perform physicochemical characterization for the Kaseesa Bhasma as per the procedure mentioned in the literature by using several analytical tools. Kaseesa was taken for preparation of Bhasma with the help of Shodhana and Marana procedures as per traditional references. The Kasisa Bhasma were distinguished for their physicochemical characters using Energy Dispersive X ray Spectroscopy EDAX , X ray diffraction XRD and Scanning Electron Microscopy SEM analysis. EDAX analysis revealed that iron, sulfur, and oxygen was found to be71.62 , 0.52 , 27.81 respectively in Kaseesa Bhasma, The XRD pattern of Kaseesa Bhasma revealed that all the strong medium and weak peaks correspond only to Fe2O3. And its crystal structure is in rhombohedral in nature, the particle size of Kaseesa Bhasma using Z average were found to be 798nm respectively. Dr. Tukaram Lamani | Dr. Ravi R Chavan | Dr. Usha M "Pharamacaeutico- Analytical Evaluation of Kaseesa Bhasma" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-6 , October 2022, URL: https://www.ijtsrd.com/papers/ijtsrd52045.pdf Paper URL: https://www.ijtsrd.com/medicine/ayurvedic/52045/pharamacaeutico-analytical-evaluation-of-kaseesa-bhasma/dr-tukaram-lamani
As the concerns over use of ayurveda medicines containing bhasmas of heavy metals are on rise, we will take a closer look at the process of preparing bhasmas and use of heavy metals prescribed in ayurveda.
Nanomedicine and Nanotechnology in Ayurvedic Pharmaceutics An Overviewijtsrd
It is a truism that what you really value is what you miss, not what you have. Ayurvedic medicine has become an extremely valuable commodity for the world today, precisely because it provides what the world misses most. The formulations like Bhasma. etc, are the oldest form of nano particles and the prime aim of such formulations is to converting minerals and metals into suitable form for their effective absorption is due to the fact that pre ”“ requisite for eliciting any pharmacodynamic response by any substance on the human system, is its absorption in the system. After marana process metals or minerals elements get transformed into organometalic compounds which are easily assumable in the biological system. Because of reduction in the particle size of material. Nano particles are 1 crore smaller times than a hair and due to its small basic characteristic also get changed. Due change in electrical, thermal, chemical and biological characteristics. These particles can in be used various technology including medical technology. Nano materials are at the leading edge of the rapidly developing field of nano technology. Their unique size dependent properties make these materials superior and indispensable in many areas of human activity. Understanding of biological processes on the nano scale level is a strong driving force behind development of nanotechnology. Therefore modern ayurveda practitioners and research personae are need to know about the concept of nano medicine for better understanding of formulations like Bhasma. etc, to keep pace with the modern system of medicine. This paper attempts to portray the use of nano technology as a tool for novel approach to evaluate the Ayurvedic pharmaceutics. Dr. Pritibala Thakur Rajput | Dr. Abdul Kareem H "Nanomedicine and Nanotechnology in Ayurvedic Pharmaceutics - An Overview" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-7 | Issue-2 , April 2023, URL: https://www.ijtsrd.com.com/papers/ijtsrd54022.pdf Paper URL: https://www.ijtsrd.com.com/medicine/ayurvedic/54022/nanomedicine-and-nanotechnology-in-ayurvedic-pharmaceutics--an-overview/dr-pritibala-thakur-rajput
Aushada is one which can be taken in disease, in alpha matra, even in severe condition, many doshas involved. Taken in specific disease, aushada which is of good quality, in proper dose should destroy it, without any complications.
Comparative Pharmaceutico Analytical Standardisation of Kaparda Bhasma with T...ijtsrd
Kaparda bhasma1 is calcium based bhasma, which are extensively used in clinical practice. In the present work kaparda bhasma prepared from kaparda with three different shodhana media. kaparda is the external shell of sea animal cyprea moneta linn. chemically kaparda identified as calcium carbonate Ca Co3 . Kaparda bhasma was prepared as per standard classical methods. Chemically analyzed all 3 different purification and final product. Physical analysis such as Ph, ash value, acid insoluble ash, water soluble ash, loss on drying and also carried out employing sophisticated instrument techniques such as XRD, FTIR, SEM EDX. Physico - chemical standards were determined for 3 groups.the data the results of prepared samples are discussed in this paper. Dr. Rohitakumar | Dr. Ravi R Chavan "Comparative Pharmaceutico-Analytical Standardisation of Kaparda Bhasma with Three Different Shodhana Media" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-6 , October 2021, URL: https://www.ijtsrd.com/papers/ijtsrd46463.pdf Paper URL : https://www.ijtsrd.com/medicine/ayurvedic/46463/comparative-pharmaceuticoanalytical-standardisation-of-kaparda-bhasma-with-three-different-shodhana-media/dr-rohitakumar
Rasashaastra literally means the “Science of Mercury”. It is a specialized branch of Ayurveda dealing mainly with materials which are known as ‘Rasa dravyaas.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
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2 Case Reports of Gastric Ultrasound
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
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NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
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The four main behavioral effects of AUD are impaired control over
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the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
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TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
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These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
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Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
3. Traditional medicine has long been
practiced in the Indo-Pak subcontinent.
Ayurvedic and Unani/Tibb are the two
most popular systems of traditional
medicine in this region. Each system
uses herbs, minerals and animal tissues
in various dosage forms.
4. Kushta/herbomineral
formulation
‘Kushta’ is one of the dosage forms prepared in a very special
manner. ‘Kushta’ the past participle of ‘KUSHTAN’ (a Persian
wordfor ‘to kill’), means ‘killed or conquered’. Primarily, a Kushta
is a blend of mineral(s) and herbal extract(s). In the traditional
system, the term is used for those dosage forms, which are
effective in small doses and are prompt in action
5. Kushta or bhasma is the finest powder form of the
medicinal preparations obtained by calcination of metal,
minerals and animal drugs.
It is easily absorbed in human body and is highly efficacious
in action.
The rate of absorption of a drug depends on particle size.
Smaller the particle size quicker and greater is the rate of
absorption.
Kushta has the smallest particle size (in nano particle range)
hence largest surface area as compared to any other solid
dosage form of Unani system of medicine therefore this
factor is responsible for rapid action of kushta.
6. History
The Horizon of Unani medicine originated
from Greece under the patronage of
Hippocrates (460 BC–377 BC)and was
developed by Arabs into an elaborated
medical science based on the frame work
of the teachings of Hippocrates and Galen
Since that time Unani Medicine has been
known as Greco-Arab medicine.
7. Unani is still popular in many Arab and
East Asian countries. In fact Unani
medicine and herbal products are
gradually more being used in many
countries where modern medicine is easily
available The indigenous systems use
mineral preparations mostly in calcined
forms: Kushta in Unani, bhasma in
Ayurveda , and Parpams in Siddha. The
usage includes even those elements
which are otherwise considered toxic
and are not administered internally in
conventional medicine
8. It is a historical truth that old Unani
physicians used some remedies
containing certain minerals, such as
salts or oxides of copper and lead.
Galen states that the efficacy of burnt
lead is unparallel in cancer and copper
was burnt before its use because it is
harmful for the body when used as it is
9. These preparations have long been used by
traditional healers and are claimed to be very
effective and are still used today in these systems.
No attempt has been made to study this type of
dosage form in a scientific manner.
This is because of a lack of communication among
traditional healers, physicians and scientists and
the unavailability of the literature in English.
Most of the books are written in the local
language and are not accessible to the rest of the
world.
Only few books have been translated into English.
Among these are ‘Hamdard Pharmacopoeia of
Eastern Medicine”
10. Uses of metal and minerals dates back
to the time of immorial
Metals were burnt in the time of Hermis
(Father of Alchemy)
Commonly used metals are Gold,
Silver, Copper, Iron, Lead and Tin and
alloy Bronze
11. Irhraq and Taklees can be used as a
synonym
Alchemist and wrote many books on
alchemy.Geber's science of al-kimiya,
from which both Arabic words
‘alchemy and chemistry stem, was
based upon the Hellenistic view that
all metals are basically the
identical matter, but with varying
impurities.
Geber, in his book Nakhbe Jabri has
mentioned the use and method of
preparing of Kushta of iron, tin,
ammonium chloride and mica, sublimation
of mercury and sulphur
12. Rhazes wrote a book “Kitab Ul Akseer’’ on
Kushtasazi (calcination) and mentioned the uses of
Kushtajat in Kitab Al Hawi.
Kushta Nuqra prepared with doodhi booti as
mughlize mani and muqawwi baah (aphrodiasiac)
kushta Hajrul yahood prepared with aab e barag
turb as mufattit hasat (lithotriptic), kushta e
faulad prepared with aab anar as muqawwi e
meda (stomachic), muqawwi jigar (liver tonic) and
prepared with sankhya .
Kushta shangaraf as muqawwi e baah
(aphrodiasiac) and mushtahi taam (appetizer),
Kitab al Taklees has also been written by Ibn e
Sina Risala dar Azkare Tanqia wa Taklees
Risala Fi al Taklees rare books on Kushta Sazi
13. Reason for using Unani
medicine
Cost effective
Safety concern
ADRs associated with allopathic drugs
14. What is Kushta???
These are herbomineral preperations
Which are blend of metals, metallic oxides,
non metals and their compounds or
minerals.
The ingredients are oxidized through the
action of heat. The preparation of a
Kushta results in the increased efficacy
of a drug, and after entering into the
body it exerts its curative role promptly and
effectively.
15. When a drug is burnt to the extent that it is
reduced to ashes then it is regarded as
Ihraq /Taklees/calcination.
This processes mentioned in various
classical Unani text books like Qarabadeen
Qadr iBayaaz Khas Firdaus Ul Hikmat
16. Possible mechanisms of action
It is likely that at higher temperatures
metals combine with organic compounds
(present in a herbs) to form organo-metallic
complexes
presence of metal may act as a catalyst in
transformation of herbal constituents to
highly active compound(s) which are
actually responsible for the therapeutic
success of the Kushta
SAR
17. Continue……………
It is also possible that the process of
preparing Kushta may transform the
heavy metals into the readily excretable
form that reduces the cumulative toxicity
of the metallic elements.
For example, EDTA forms highly water-
soluble complex with lead and renders it
to be excreted through urine. Therefore,
it is used in lead poisoning
18. Kushta (calcined product) is easily absorbed
in human body and is highly efficacious in its
action.
A small amount of kushta can be used for
wide range of therapeutics depending upon
the process of formulation.
Kushta has always been neglected and
not studied scientifically.
Few scientific reports are available on kushta
and other drugs of mineral origin. Kushta
are biological nanocrystals.
Nanocrystalline materials are solids composed
of crystallites with size less than 100 nm in at
least one dimension.
19. It is claimed by the
healers that these
techniques increases the
efficacy of drug and also
either completely remove
the elements of toxicity at
all or downgrade them to
the level where the drug
can be safely used .
20. Method of preperation
Classically mineral and animal origin
drugs are calcined in crucibles and in
pits of different sizes by special
processses, having varying numbers of
cow dung cakes and with different
intensity of heat. The resultant product
(Kushta) obtained is in the form of fine
powder.
It is administered orally in small dose
with suitable vehicle to make them
biocompatible. The efficacy of kushta
depends upon the processing method.
Ores are roasted by heating them at high
temperature but below the melting point
21. Sequential chart for preparation
of kushta
purification
powdering
Stirring washing
filtration
Heating Trituration
Coating
Detoxification
22. Purification
The principal objective purification is to
remove unwanted part from the raw
material and separate out.
"The sheets of metals are heated till red
hot and are successively dipped into
liquids like oil, buttermilk. The procedure
is repeated seven times".
23. Powdering
a change is brought about in the chemical form
or state of the metal. This makes it to lose its
metallic characteristics and physical nature. In
short, after powdering, metal can be converted
into powder or other form suitable for
administration.
Mercury is often used because of unique
property of mercury to amalgamate with many
metals must have been the reason behind its
maximum use in kushta preperation.
24. Stirring
Process of stirring during heating the
metal . Stirring is carried out either with
iron rod or stick made from a specific
plant. As we know today, iron serves as
catalyst in many chemical reactions. The
phytoconstituents of plant stick may be
enhancing the therapeutic effect. For
example, stick of Neem is used for
stirring process due to its antiseptic
property.
25. Washing
In this process, several water washes
are given to the product obtained in the
previous stage. Perhaps this is to
remove the excess amounts of agents
used in previous stages. Such agents
may adversely affect the quality of final
product. Hence intermediates are
washed with water, thereby water-
soluble constituents are removed.
26. Filteration
The product is then sifted either through a fine
cloth or through sieves of suitable mesh so as
to separate residual material larger in size
Heating and Trituration
Heating is done again after filtration and drug is
triturates with herbs and herbal extracts.
Detoxification
Calcination,the general term used for heating in
the process of kushta. A special earthen pot,
boota is generally used for the process. Its
shallowness is useful in heating the material
faster and uniformly.
27. Special Method of preparation
Before making drugs are cleaned and this the
drugs are ground in a pestle and mortar (Kharal)
with for a specified period of time .Thereafter small
cakes of varying sizes and thickness are made.
These cakes are well dried in the shade and are put
in earthen discs and the process of Gil-e-Hikamat is
followed and the whole apparatus is dried. After this
a pit is dug in an open space. Half the pit is filled
with cowdung cakes. The apparatus (sealed
earthen discs) is now placed in the pit and the
remaining space is filled with more cow dung cakes
which are then ignited. After the calcination is over,
the pit is allowed to cool completely, the apparatus
is removed and the contents, thus obtained, are
again powdered.
28. Aims of Taklees
To change a hard and unabsorbable drug
into absorbable form .
To remove undesirable parts of the drug e.g.
Crab and Stag horn are burnt to remove
undesired fluids contain in them.
To make a hard drug soft enough to
pound eas ily, e.g. Ruby.
To remove toxic effect of drug, e.g.
Scorpion and Snake are burnt to remove
their poison.
To decrease the toxic effects of a drug.
To increase the efficacy and potency of a drug.
29. ADVANTAGES OF
TAKLEES
Low dose and high efficacy.
Use is easy as compared to other dosage forms.
Some kushta are unparalleled as aphrodisiac.
Most of the kushta stimulates innate heat of the body.
Kushta is more stable than other dosage forms.
Only dosage form in which a bio incompatible substance is
made biocompatible
Only dosage form that can be given in acute conditions.
It is a dosage form which induces the change in
temperament of the drug e.g. the temperament of Sadaf is
cold and dry but its Kushta has temperament hot and dry Can
be used in the patient of such diseases where uptake of
large doses of medicine is not contraindicated
All the kushtajat are very potent by their action and this
property of kushtajat is used in presence of severe diseases.
The older the Kushta better the effect
30. GENERAL PRECAUTIONS FOR PREPARATION
OF KUSHTA
1. The material used for the preparation of
Kushta should be of the best quality.
2. While making the Kushta , any addition
and deletion of any of the item, duration
and the mode of mortaring, the fire used
to be subjected, should strictly be
followed according to the text.
3. When the fresh juice of an herb is
added it should be either Muqatar
(distilled) or Murawwaq (filtered)
31. 4. When dried herb is added, it should not be more
than one year old.
5. Highest precautions should be taken in
subjecting the Boota (crucible) to the fire.
(a)Fluctuation in the intensity of the heat should be
avoided.
(b)The ‘ boota’ should be subjected to the fire of
the cow
dung cakes or coal according to the method
given in the classical text.
6. Place at which Kushta is prepared should be air
protected
32. PRELIMINARY TESTS
1. Loss of metallic luster
When visually examined preferably in presence of sun light
no metallic luster should be observed.
2. Fineness test
On rubbing a small quantity of the sample between the
fingers it should enter into the lines on the fingers.
3. Floating test
If a small quantity of kushta is sprinkled on water surface it
should float on the surface,but this property of a Kushta is not
standard parameter because this property can be found in
various other substances like wood dust. Floating on water
only indicates the lightness of kushta
4. The Kushta should not revert to the original state
T
33. Continue……..
The kushta of a non metal should not emit smoke when
placed on fire.
6. Loss of metallic state .
This involves heating of a very thin silver sheet (600
nm thickness) along with a small quantity of kushta to red
hot for about 5 min. After cooling the sheet to room
temperature, no traces of this sample should
permanently stick to the silver sheet indicating no
alloy formation takes place, thus confirming the
metal has totally transformed into kushta , its oxide
form
.
7. When thrown over wall then the prepared kushta
should stick to the wall
34. Some of the Kushtas used in traditional medicine of Indo-Pak subcontinent
Element Preparation Mineral Herb uses
Calcium Kushta Sadaf Oyster shell Rosa
damascena
cardiotonic
Mercury Kushta para mercury Listeria chinesis Paralysis,
asthma, and
impotence
Iron Kushta Faulad Iron dust Aloe
barbadensis
Tonic especially
haemantinic
Tin Kushta Qalai Tin Aloe
barbadenis
impotence
Arsenic Kushta
Gaudanti
Arsenic
trisulphide
Aloe
barbadenis
Rheumatism
Copper Kushta Tamba
sufaed
Copper dust Capparis
decidua
Cough and
asthma