2. Etymology
O Sweta indicates the white colour and the Sanskrit word
“Parpati” denotes a thin flake like preparation.
O Kshara Parpati
SYNONYM :
3. Introduction
O Sweta parpati is an Ayurvedic medicine coming in Parpati kalpana,
used in the treatment of difficulty in urination, urinary calculi,
dyspepsia etc. This is also known as Kshara parpati.
O Sweta Parpati is different from other Parpati kalpas since it does not
contain Parada and Gandhaka as its ingredient. It contains
Suryakshara, Sphatika and Navasadara as main ingredients as per
AFI and Sidhayogasangraha.
O Rasodharatantra mentions the addition of Tankana and Karpura to
improve the therapeutic efficacy of the formulation.
4. Ingredients
INGREDIENTS PARTS USED
SURYA KSHARA 16 PART
SPHATIKA 2 PART
NAUSADARA 1 PART
According to A.F.I. and Sidhayogasangraha
DOSE : 725 mg to 1.250 gm
ANUPANA : SITAL JALA , NARIKELA JALA, SARKARA YUKTA JALA
5. Sr.
no
Name of ingredient Parts used Melting
point
1 Surya Kshara 20 Parts 334℃
2 Sphatika 5 Parts 92-95℃
3 Tankana 3 Parts 743℃
4 Karpura 3 Parts 175℃
5 Navasadara 3 Parts 338℃
According to Rasodhhar Tantra
DOSE : 125 mg to 1.25 gm
Shelf life : 2 Years (revised rule 161 B)
6. Indications
O Rogadhikar - Mutrakrichha (Dysuria)
O Mutraghat (Urinary retention)
O Ashmari (Renal calculi)
O Alpamutrata (Oligouria)
7. Materials & Method
O Material required for general method of
preparation :
Kharal yantra, Mud Sharava, Gas burner, flat non
reactive cooling surface, metal tongs, air tight
containers.
O Their are 3 stages of preparation :
Poorva karma
Pradhan karma
Paschat karma
8. O Poorva karma includes grinding and mixing of
Asudhha Surya Kshara, Sphatika and Navasadara
in the ratio of 16:2:1.
O Then collected powder is taken in the Mud
sharava.
9. O Pradhan karma includes heating of this mixture in
mud sharava over fire till the complete melting to
liquid stage.
O Then it is quickly spread over the flat non reactive
surface for cooling.
10. O Paschata Karma includes collection of this white
flakes like Sweta Parpati and storage in the air
tight containers after grinding into fine powder.
11. O Preparation of 5 batches of Sweta Parpati
Sr. No. Initial wt. Final wt. Melting time Loss of wt. % Yield
1 19gm 14gm 3min 5gm 73.68
2 19gm 15gm 2min 4gm 78.94
3 19gm 15gm 2min 4gm 78.94
4 19gm 15gm 2min 4gm 78.94
5 38gm 28gm 2min 10gm 73.68
In this procedure flat clean non reactive surface was used for the cooling
of molten mixture.
Ph of the raw material was 6.4
Ph of the product was 6.9
19. Another method of forming
flakes in circular form
O In this method of Sweta Parpati formation, pestle
of porcelain Khalva yantra is dipped into the
molten mixture and circular uniform shape of
parpati is obtained instead of spreading on a flat
surface.
20. O Preparation of 1 batch by using Pestle method
Initial wt. of ingredients = 190gm
As. Navasadar = 10gm
As. Sphatika = 20gm
As. Surya Kshara = 160gm
Final wt. of product = 140gm
Loss of wt. = 50gm
% Yield = 73.68%
Total melting time was 3 min.
Ph was found 6.5 (10% aq.sol)
21. Observations
O In the initial stage of melting the powder mixture appears to be
hydrolyzed.
O Yellowish colour appears in the starting stage of melting.
O Smell of ammonia is also observed during melting.
O Solution becomes nearly transparent on complete melting.
O On cooling the product becomes bright white in color.
O Product is odourless with tingling cold taste.
O Most commonly 73.68% yield is obtained in this formulation.
24. Chemical properties of ingredients
Surya
Kshara
Sphatika Navasadara Tankana Karpura
IUPAC
NAME
Pottasium
Nitrate
Pottasium
Aluminiu
m
disulphate
Ammonium
chloride
Sodium
tetraborate
decahydrat
e
1,7,7
Trimethylbi
cyclo[2.2.1]
heptan-2-
one
FORMU
LA
KNO3 KAl(SO4)
2.12H2O
NH4Cl Na2B4O7.1
0H2O
C10H16O
M.P. 334 ℃ 92 TO 95
℃
338 ℃ 743 ℃ 175-177 ℃
B.P. 400 ℃ 200 ℃ 520 ℃ 1575 ℃ 209 ℃
Ph 6.2
(10%aq.
sol)
3.0 to 4.0
(10% aq.
Sol.)
4.6 to 6.0 (5%
aq. Sol.)
9.2 (1% aq.
Sol.)
----
LD50 1901mg/kg
(oral,
rabbit)
--- 1650 mg/kg
(oral, rats)
4550-4980
mg/kg
(oral, rats)
50-500
mg/kg orally
25. Common Pharmacological uses of ingredients
Ingredient Pharmacological uses
Surya Kshara used in toothpaste for sensitive teeths, historically
used to treat asthma, once used as hypotensive
agent.
Sphatika Astringent, styptic and antiseptic, natural deodorant
– bacterial growth inhibition, to reduce bleeding, to
remove pimples, acne, topically cauterize apthous
ulcer
Navasadara As an expectorant in cough syrups, systemic
acidifying agent in severe metabolic alkalosis, in oral
acid loading test to diagnose distal renal tubular
acidosis, to maintain the urine at an acidic ph in
treatment of some UTI.
Tankana Anti fungal preparation, fluoride detoxification, as a
food additive
Karpura Readily absorbed through skin, cool feeling when applied
gently and warm when applied vigorously, slight local
anaesthesia, secondary antimicrobial, produce
tachycardia, flushing, perspiration, urination.
26.
27. O CONCLUSION :
Instead of Lauha Darvi as used in the other Parpati Kalpanas,
Mud Sharava is used to melt the ingredients.
The melting point of ingredients used in the Sweta Parpati is
high when compared to other Rasa Gandha Parpati.
There is no need of smearing Ghee in the vessel as Kshariya
ingredients will not stick on the pot.
Corrosive nature of its ingredients can cause charring of the
Kadalipatra and Kashaya property of the leaves can interfere in
the main therapeutic indication of this parpati i.e. Mutrakrichha.
Hence pouring of its content into kadalipatra is not required.
Tankana has therapeutic effect on uterine infections and
Karpura increases the urine output. Hence these ingredients add
to the therapeutic value of Sweta Parpati but higher melting
point of Tankana and volatile nature of Karpura makes the
formulation difficult.
28.
29. O CONCLUSION :
Colour of final product was Ishat Pitabh Shweta Varna
with Sodhita and Nirmalikrita ingredients while it was
bright white with Asodhita ingredients.
Temperature required for total melting as follows :
Asodhita ingredients – 220 to 226 ℃
Sodhita ingredients – 218-229 ℃
Nirmalikrita - 167-208 ℃
Sodhita sample shows least loss of weight as compared to
other two methods.
Sodhita sample shows higher hardness than other two
methods.
30. Asodhita sample is smoother than other two
methods.
Ph seen from samples as below :
Asodhita – 8.3
Sodhita – 7.6
Nirmalikrita – 6.2
Time taken for melting was least in Asodhita sample
as compared to other two.
Since Sweta parpati is used as alkanizer in
Mutravikara, it is better to use Asodhita ingredients
which also convenient method.