This document discusses food as a vehicle for the transmission of cholera. It notes that foods can become contaminated with Vibrio cholerae during preparation, especially by infected food handlers in unsanitary environments. Several foods have been implicated in cholera outbreaks, including seafood like fish, shellfish, and crabs due to their ability to harbor V. cholerae. Other foods like rice, vegetables, and dairy products can also transmit cholera if contaminated. Proper food handling and hygienic practices are recommended to reduce the risk of foodborne cholera transmission.
This document summarizes emerging and re-emerging infectious diseases. It lists the top causes of mortality from infectious diseases according to WHO, including respiratory infections, diarrheal diseases, HIV/AIDS, tuberculosis, and malaria. An emerging disease is defined as one that is newly appearing or increasing in incidence or range. Examples of recent emerging diseases mentioned include hepatitis C, hepatitis B, and SARS. Factors that can contribute to disease emergence include properties of the agent, host, and environment. Several current and historical emerging diseases are described in more detail such as dengue fever, leptospirosis, AIDS, tuberculosis, avian influenza, Ebola hemorrhagic fever, Marburg virus, and Middle East respiratory syndrome
Epidemiology and Control Measures for CholeraAB Rajar
It is an acute diarrheal disease caused by Vibrio Cholera typically characterized by sudden onset of profuse,effortless,watery diarrhea followed by vomiting, rapid dehydration, muscular cramps and suppression of urine.
Water-borne diseases are illnesses caused by ingesting water contaminated with human or animal waste containing pathogens. They are a major global public health issue, causing over 2 million deaths annually, especially among children in developing countries. Improving access to clean water and sanitation could reduce the global disease burden by an estimated 4%. Common water-borne diseases are caused by bacteria, viruses, protozoa and parasites transmitted via contaminated water sources.
Cholera is an acute diarrheal illness caused by the bacterium Vibrio cholerae found in contaminated food or water. It can lead to severe dehydration and death if untreated. Symptoms include watery diarrhea, vomiting, and leg cramps. Treatment involves oral rehydration therapy to replace lost fluids, along with antibiotics. Prevention relies on access to clean water, proper sanitation, and thorough cooking of food. Cholera remains a risk in areas with poor sanitation and is spread through contaminated water and food sources.
what is waterborne diseases? example,types of water borne diseases,disease pathway,route of infection,how climate control water borne disease trends,case study of cholera in south asia,application of remote sensing on study of waterborne diseases
This document discusses various water-borne diseases caused by pathogenic microorganisms. It describes several bacterial diseases including salmonellosis caused by Salmonella bacteria, which causes gastroenteritis; campylobacteriosis caused by Campylobacter bacteria; shigellosis caused by Shigella bacteria, which causes dysentery; and cholera caused by Vibrio cholerae bacteria, which causes a large amount of watery diarrhea. It also discusses viral diseases including hepatitis A and rotavirus, parasitic diseases such as cryptosporidiosis and giardiasis, and diseases transmitted by water like leptospirosis. Water contamination by human or animal waste is a major cause of these water-borne infectious
Source & Factors Related to Fish & Shrimp Disease in BangladeshAsrafurTalha1
This document discusses the sources and factors related to fish and shrimp disease in Bangladesh. It identifies several sources of infection for fish diseases, including direct contact with pathogens, contact with diseased organisms, soil contact, secondary infections, waterborne infections, direct entry of pathogens, migration, contamination, contact with pollution, and other sources. It also examines factors that can affect fish and shrimp diseases, such as environmental factors, hereditary factors, glandular dysfunction, mechanical injury, pathogenic organisms, atypical cell growth, and dietary deficiencies. The document recommends strategies for pathogen identification, avoidance of introduction, control of spread, and quarantine to address fish and shrimp diseases.
Water borne diseases due to consumption of contaminated water in India are the common and the main reason is unsafe drinking water supply, poor sanitation and hygiene. Let's take a look at Top 4 Water Borne Diseases in India caused by drinking contaminated water.
This document summarizes emerging and re-emerging infectious diseases. It lists the top causes of mortality from infectious diseases according to WHO, including respiratory infections, diarrheal diseases, HIV/AIDS, tuberculosis, and malaria. An emerging disease is defined as one that is newly appearing or increasing in incidence or range. Examples of recent emerging diseases mentioned include hepatitis C, hepatitis B, and SARS. Factors that can contribute to disease emergence include properties of the agent, host, and environment. Several current and historical emerging diseases are described in more detail such as dengue fever, leptospirosis, AIDS, tuberculosis, avian influenza, Ebola hemorrhagic fever, Marburg virus, and Middle East respiratory syndrome
Epidemiology and Control Measures for CholeraAB Rajar
It is an acute diarrheal disease caused by Vibrio Cholera typically characterized by sudden onset of profuse,effortless,watery diarrhea followed by vomiting, rapid dehydration, muscular cramps and suppression of urine.
Water-borne diseases are illnesses caused by ingesting water contaminated with human or animal waste containing pathogens. They are a major global public health issue, causing over 2 million deaths annually, especially among children in developing countries. Improving access to clean water and sanitation could reduce the global disease burden by an estimated 4%. Common water-borne diseases are caused by bacteria, viruses, protozoa and parasites transmitted via contaminated water sources.
Cholera is an acute diarrheal illness caused by the bacterium Vibrio cholerae found in contaminated food or water. It can lead to severe dehydration and death if untreated. Symptoms include watery diarrhea, vomiting, and leg cramps. Treatment involves oral rehydration therapy to replace lost fluids, along with antibiotics. Prevention relies on access to clean water, proper sanitation, and thorough cooking of food. Cholera remains a risk in areas with poor sanitation and is spread through contaminated water and food sources.
what is waterborne diseases? example,types of water borne diseases,disease pathway,route of infection,how climate control water borne disease trends,case study of cholera in south asia,application of remote sensing on study of waterborne diseases
This document discusses various water-borne diseases caused by pathogenic microorganisms. It describes several bacterial diseases including salmonellosis caused by Salmonella bacteria, which causes gastroenteritis; campylobacteriosis caused by Campylobacter bacteria; shigellosis caused by Shigella bacteria, which causes dysentery; and cholera caused by Vibrio cholerae bacteria, which causes a large amount of watery diarrhea. It also discusses viral diseases including hepatitis A and rotavirus, parasitic diseases such as cryptosporidiosis and giardiasis, and diseases transmitted by water like leptospirosis. Water contamination by human or animal waste is a major cause of these water-borne infectious
Source & Factors Related to Fish & Shrimp Disease in BangladeshAsrafurTalha1
This document discusses the sources and factors related to fish and shrimp disease in Bangladesh. It identifies several sources of infection for fish diseases, including direct contact with pathogens, contact with diseased organisms, soil contact, secondary infections, waterborne infections, direct entry of pathogens, migration, contamination, contact with pollution, and other sources. It also examines factors that can affect fish and shrimp diseases, such as environmental factors, hereditary factors, glandular dysfunction, mechanical injury, pathogenic organisms, atypical cell growth, and dietary deficiencies. The document recommends strategies for pathogen identification, avoidance of introduction, control of spread, and quarantine to address fish and shrimp diseases.
Water borne diseases due to consumption of contaminated water in India are the common and the main reason is unsafe drinking water supply, poor sanitation and hygiene. Let's take a look at Top 4 Water Borne Diseases in India caused by drinking contaminated water.
Cholera is an acute diarrheal infection of the small intestine caused by the ingestion of food and water contaminated by bacterium vibrio cholera. An estimated 3–5 million cholera cases resulting to about 120 000 deaths yearly. Nigeria accounts for 38% of cases from Africa with 44,456 cases, with highest case fatality rate (CFR) of 5.1% in Sub-Sahara Africa (WHO, 2010). In Nigeria, 18 States in 2010 reported the outbreak of cholera with about 41,787 cases and1,716 deaths (case-fatality rate [CFR]: 4.1%). In 2010, men had a higher prevalence (5.1%) than in women (4.9%)
This document discusses waterborne diseases and epidemics caused by contaminated drinking water. It outlines various bacteria, viruses, and protozoa that can be transmitted through water and cause diseases like cholera, typhoid fever, diarrhea, and jaundice. Treatment of drinking water through chlorination and water filtration has reduced waterborne disease outbreaks in developed nations. However, in developing parts of the world where water treatment is not universal, waterborne illnesses remain a major public health issue. The document emphasizes the importance of access to safe drinking water and proper sanitation globally.
GLOBAL ENVIRONMENTAL CHALLENGES, HUMAN HEALTH AND DISEASEDR SARITA SHARMA
DETAILS ON ORIGIN OF HUMAN CIVILIZATIONENVIRONMENTAL ISSUES, HUMAN HEALTH MAN AND ENVIRONMENT RELATIONSHIP AND SOLUTION OF ALL THE ENVIRONMENTAL ISSUES
This document discusses water borne diseases, specifically focusing on cholera. It provides details on the causative organism Vibrio cholerae, including its morphology, growth characteristics, biochemical properties, and methods for laboratory diagnosis. The key clinical features of cholera including rice water stools and mechanisms of pathogenesis are summarized. Methods for treatment, prevention and control of cholera outbreaks are also outlined.
This document appears to be a biology project report on common human diseases prepared by a student named Abhishek Dhinge. It includes an introduction that defines disease and discusses sources and types of diseases. It also summarizes modes of transmission of communicable diseases. The report then provides more detailed descriptions of specific viral diseases like rabies and AIDS, bacterial diseases like typhoid, and protozoan diseases like malaria. It concludes with some key facts about cancer. The project was guided by a teacher and certified to fulfill requirements for the student's biology class.
This document discusses poliomyelitis (polio), a waterborne disease caused by the poliovirus. It first provides an overview of waterborne diseases and describes the three forms of polio: subclinical, non-paralytic, and paralytic. It then discusses the methodology, symptoms, objects/causes, and consequences of polio. The document recommends various solutions like vaccines, sanitation, hygiene and treatment. It concludes that polio spreads through fecal-oral transmission and was eliminated in Vietnam through extensive vaccination programs, though prevention is still needed.
Cholera is an acute diarrheal disease caused by the bacterium Vibrio cholerae. It remains a global threat, with an estimated 100,000-120,000 deaths per year. The disease spreads through contaminated food and water and outbreaks often occur in areas with poor sanitation and limited access to clean water. While most infected individuals are asymptomatic, cholera can cause severe dehydration and death if left untreated. Effective treatment involves oral rehydration therapy. Prevention relies on vaccination, improved water quality, sanitation and hygiene. The WHO recommends surveillance, preparedness, treatment and use of oral cholera vaccines to control outbreaks.
Dengue fever is caused by the dengue virus transmitted through mosquito bites. Common symptoms include fever, headache, muscle and joint pains, and a rash. In some cases it can develop into life-threatening dengue hemorrhagic fever or dengue shock syndrome. There is no vaccine, so prevention focuses on reducing mosquito habitats and exposure to bites.
The document discusses water and waterborne diseases. It defines key terms, describes the water cycle and classification of waterborne diseases. Waterborne diseases are spread through contaminated water and include diarrhea-causing and non-diarrhea causing illnesses. Common diarrhea-causing pathogens discussed are rotavirus, E. coli, and cryptosporidium. Typhoid fever and hepatitis are covered as non-diarrheal diseases. The document also addresses water purification methods including boiling, filtration and disinfection on small and large scales.
Water-borne diseases and water-caused health problems are mostly due to inadequate and incompetent management of water resources. Sometimes the water gets contaminated at source due to various reasons and mainly due to inflow of sewage into the source.
Water borne diseases, prevention and guidelines for safe drinking waternavjotjyoti
Water borne diseases are acquired by drinking contaminated water or contact with contaminated recreational water. They account for 4.1% of global disease burden and 1.8 million deaths annually. Diseases are classified as water-washed, water-scarce, water-based, and vector-borne. Guidelines for safe drinking water include treating water through coagulation, sedimentation, filtration, and disinfection to remove pathogens and chemicals. Public education on water sources, treatment, and health risks is also important to prevent water borne diseases.
This document discusses waterborne diseases and their impact. It notes that waterborne diseases cause over 2 million deaths and 4 billion cases of diarrhea annually, mostly in children in developing countries. It defines different types of waterborne diseases including water-borne (caused by ingestion of contaminated water), water-washed (caused by contact with contaminated water), water-based (parasites found in water organisms), and water-related (vector-borne diseases near contaminated water). It provides numerous examples and details of pathogenic bacteria, viruses, protozoa and helminths that can cause these diseases.
Microorganisms have been used as biological weapons throughout history. This document discusses the role of microorganisms in biological warfare and bioterrorism. It defines biological warfare and lists some key characteristics that make microorganisms suitable agents. The document then reviews the history of biological warfare and provides examples of past uses of microorganisms as weapons. It also discusses bioweapons, bioterrorism principles, categories of biological agents, and provides details on specific agents like anthrax and their use in anti-agriculture warfare.
Foodborne, commonly called food poisoning, and waterborne illnesses are conditions caused by eating or drinking food or water that is contaminated by microbes or the toxins they produce. They typically cause gastrointestinal symptoms such as abdominal pain, nausea, vomiting, and diarrhea.
It is about sanitation and public health microbiology with special reference to Bangladesh. It covers: water supply, the use of safe water, sanitation, disposal of human excreta and refuse.
Waterborne diseases are caused by microorganisms, toxins, and contaminants spread through contaminated water. They cause illnesses such as cholera, diarrhea, and gastrointestinal problems. Developing countries often lack proper water treatment, especially in rural areas, increasing risk of outbreak. The document then discusses four specific waterborne diseases - diarrhea, cholera, typhoid, and amoebiasis - outlining their causes, symptoms, and treatments.
This presentation is dedicated to the eradication project undertaken by Carter Center of Guinea worms in tropical region and propose some longtime solutions for this disease which has no cure.
This document discusses bioterrorism and various biological agents that could potentially be used as bioweapons. It defines bioterrorism and describes biological weapons as microbes or their toxins. Various microorganisms are discussed in detail, including anthrax, plague, smallpox, viral hemorrhagic fevers like Ebola, and biological toxins such as botulinum toxin. For each agent, the document covers characteristics, potential use as a bioweapon, symptoms, diagnosis, treatment and other relevant details.
Breaking the Nonprofit Starvation CycleDavid Johnson
The greatest challenge facing nonprofit organizations is a scarcity mindset and the underinvestment that comes from it.
When checked at an early stage, the scarcity mindset is only a hindrance, but for too many nonprofits, it gives rise to a vicious cycle of short-termism that can threaten even the most storied organizations.
Renee Richardson on Nonprofit AccountingJanice Dru
Renee Richardson, Chief Financial Officer at Population Council (http://www.popcouncil.org), presented on August 20, 2015 on the topic of "Nonprofit Accounting." She spoke to the Nonprofit Executive Directors group (http://bit.ly/nedgroup and http://bit.ly/nedmeet) - on LinkedIn and Meetup. Watch or listen to past recordings of NED events on YouTube: https://www.youtube.com/channel/UCOGxWhkQlwTU-Y80bcy2Dgg
Taylor faith philapnthropy and change 2015Nick Wallace
Small nonprofits need good accounting and reporting systems just like large organizations. Find out how to do this right in a small organization. Check out the Faith Philanthropy and Change Conference at Taylor University on June 8 and 9. Register at taylorconnect.org/nonprofitconference2015 See you there!
Cholera is an acute diarrheal infection of the small intestine caused by the ingestion of food and water contaminated by bacterium vibrio cholera. An estimated 3–5 million cholera cases resulting to about 120 000 deaths yearly. Nigeria accounts for 38% of cases from Africa with 44,456 cases, with highest case fatality rate (CFR) of 5.1% in Sub-Sahara Africa (WHO, 2010). In Nigeria, 18 States in 2010 reported the outbreak of cholera with about 41,787 cases and1,716 deaths (case-fatality rate [CFR]: 4.1%). In 2010, men had a higher prevalence (5.1%) than in women (4.9%)
This document discusses waterborne diseases and epidemics caused by contaminated drinking water. It outlines various bacteria, viruses, and protozoa that can be transmitted through water and cause diseases like cholera, typhoid fever, diarrhea, and jaundice. Treatment of drinking water through chlorination and water filtration has reduced waterborne disease outbreaks in developed nations. However, in developing parts of the world where water treatment is not universal, waterborne illnesses remain a major public health issue. The document emphasizes the importance of access to safe drinking water and proper sanitation globally.
GLOBAL ENVIRONMENTAL CHALLENGES, HUMAN HEALTH AND DISEASEDR SARITA SHARMA
DETAILS ON ORIGIN OF HUMAN CIVILIZATIONENVIRONMENTAL ISSUES, HUMAN HEALTH MAN AND ENVIRONMENT RELATIONSHIP AND SOLUTION OF ALL THE ENVIRONMENTAL ISSUES
This document discusses water borne diseases, specifically focusing on cholera. It provides details on the causative organism Vibrio cholerae, including its morphology, growth characteristics, biochemical properties, and methods for laboratory diagnosis. The key clinical features of cholera including rice water stools and mechanisms of pathogenesis are summarized. Methods for treatment, prevention and control of cholera outbreaks are also outlined.
This document appears to be a biology project report on common human diseases prepared by a student named Abhishek Dhinge. It includes an introduction that defines disease and discusses sources and types of diseases. It also summarizes modes of transmission of communicable diseases. The report then provides more detailed descriptions of specific viral diseases like rabies and AIDS, bacterial diseases like typhoid, and protozoan diseases like malaria. It concludes with some key facts about cancer. The project was guided by a teacher and certified to fulfill requirements for the student's biology class.
This document discusses poliomyelitis (polio), a waterborne disease caused by the poliovirus. It first provides an overview of waterborne diseases and describes the three forms of polio: subclinical, non-paralytic, and paralytic. It then discusses the methodology, symptoms, objects/causes, and consequences of polio. The document recommends various solutions like vaccines, sanitation, hygiene and treatment. It concludes that polio spreads through fecal-oral transmission and was eliminated in Vietnam through extensive vaccination programs, though prevention is still needed.
Cholera is an acute diarrheal disease caused by the bacterium Vibrio cholerae. It remains a global threat, with an estimated 100,000-120,000 deaths per year. The disease spreads through contaminated food and water and outbreaks often occur in areas with poor sanitation and limited access to clean water. While most infected individuals are asymptomatic, cholera can cause severe dehydration and death if left untreated. Effective treatment involves oral rehydration therapy. Prevention relies on vaccination, improved water quality, sanitation and hygiene. The WHO recommends surveillance, preparedness, treatment and use of oral cholera vaccines to control outbreaks.
Dengue fever is caused by the dengue virus transmitted through mosquito bites. Common symptoms include fever, headache, muscle and joint pains, and a rash. In some cases it can develop into life-threatening dengue hemorrhagic fever or dengue shock syndrome. There is no vaccine, so prevention focuses on reducing mosquito habitats and exposure to bites.
The document discusses water and waterborne diseases. It defines key terms, describes the water cycle and classification of waterborne diseases. Waterborne diseases are spread through contaminated water and include diarrhea-causing and non-diarrhea causing illnesses. Common diarrhea-causing pathogens discussed are rotavirus, E. coli, and cryptosporidium. Typhoid fever and hepatitis are covered as non-diarrheal diseases. The document also addresses water purification methods including boiling, filtration and disinfection on small and large scales.
Water-borne diseases and water-caused health problems are mostly due to inadequate and incompetent management of water resources. Sometimes the water gets contaminated at source due to various reasons and mainly due to inflow of sewage into the source.
Water borne diseases, prevention and guidelines for safe drinking waternavjotjyoti
Water borne diseases are acquired by drinking contaminated water or contact with contaminated recreational water. They account for 4.1% of global disease burden and 1.8 million deaths annually. Diseases are classified as water-washed, water-scarce, water-based, and vector-borne. Guidelines for safe drinking water include treating water through coagulation, sedimentation, filtration, and disinfection to remove pathogens and chemicals. Public education on water sources, treatment, and health risks is also important to prevent water borne diseases.
This document discusses waterborne diseases and their impact. It notes that waterborne diseases cause over 2 million deaths and 4 billion cases of diarrhea annually, mostly in children in developing countries. It defines different types of waterborne diseases including water-borne (caused by ingestion of contaminated water), water-washed (caused by contact with contaminated water), water-based (parasites found in water organisms), and water-related (vector-borne diseases near contaminated water). It provides numerous examples and details of pathogenic bacteria, viruses, protozoa and helminths that can cause these diseases.
Microorganisms have been used as biological weapons throughout history. This document discusses the role of microorganisms in biological warfare and bioterrorism. It defines biological warfare and lists some key characteristics that make microorganisms suitable agents. The document then reviews the history of biological warfare and provides examples of past uses of microorganisms as weapons. It also discusses bioweapons, bioterrorism principles, categories of biological agents, and provides details on specific agents like anthrax and their use in anti-agriculture warfare.
Foodborne, commonly called food poisoning, and waterborne illnesses are conditions caused by eating or drinking food or water that is contaminated by microbes or the toxins they produce. They typically cause gastrointestinal symptoms such as abdominal pain, nausea, vomiting, and diarrhea.
It is about sanitation and public health microbiology with special reference to Bangladesh. It covers: water supply, the use of safe water, sanitation, disposal of human excreta and refuse.
Waterborne diseases are caused by microorganisms, toxins, and contaminants spread through contaminated water. They cause illnesses such as cholera, diarrhea, and gastrointestinal problems. Developing countries often lack proper water treatment, especially in rural areas, increasing risk of outbreak. The document then discusses four specific waterborne diseases - diarrhea, cholera, typhoid, and amoebiasis - outlining their causes, symptoms, and treatments.
This presentation is dedicated to the eradication project undertaken by Carter Center of Guinea worms in tropical region and propose some longtime solutions for this disease which has no cure.
This document discusses bioterrorism and various biological agents that could potentially be used as bioweapons. It defines bioterrorism and describes biological weapons as microbes or their toxins. Various microorganisms are discussed in detail, including anthrax, plague, smallpox, viral hemorrhagic fevers like Ebola, and biological toxins such as botulinum toxin. For each agent, the document covers characteristics, potential use as a bioweapon, symptoms, diagnosis, treatment and other relevant details.
Breaking the Nonprofit Starvation CycleDavid Johnson
The greatest challenge facing nonprofit organizations is a scarcity mindset and the underinvestment that comes from it.
When checked at an early stage, the scarcity mindset is only a hindrance, but for too many nonprofits, it gives rise to a vicious cycle of short-termism that can threaten even the most storied organizations.
Renee Richardson on Nonprofit AccountingJanice Dru
Renee Richardson, Chief Financial Officer at Population Council (http://www.popcouncil.org), presented on August 20, 2015 on the topic of "Nonprofit Accounting." She spoke to the Nonprofit Executive Directors group (http://bit.ly/nedgroup and http://bit.ly/nedmeet) - on LinkedIn and Meetup. Watch or listen to past recordings of NED events on YouTube: https://www.youtube.com/channel/UCOGxWhkQlwTU-Y80bcy2Dgg
Taylor faith philapnthropy and change 2015Nick Wallace
Small nonprofits need good accounting and reporting systems just like large organizations. Find out how to do this right in a small organization. Check out the Faith Philanthropy and Change Conference at Taylor University on June 8 and 9. Register at taylorconnect.org/nonprofitconference2015 See you there!
Year-End Survival Tips For the Nonprofit AccountantNet at Work
Like most Nonprofits, your finance team is sure to be steeped in deadlines closing out year-end & while it's clearly a trying time for accounting staff - there are ways to help.
This one deals with non profit accounting issues including a couple of terms that you should be familiar with, what's similar to financial accounting and what’s different from financial accounting.
The accounting cycle involves recording business transactions in a journal throughout the month. At month-end, adjusting entries are made to properly allocate revenues and expenses to the correct period. Closing entries are then made to zero out temporary accounts and prepare the financial statements for the period, including the income statement and balance sheet. This process repeats at the start of each new accounting period.
The document discusses various accounting concepts and procedures including:
1) Recording transactions in a journal, posting to ledgers, preparing trial balances and final accounts.
2) The fundamental accounting principle that assets equal liabilities plus capital.
3) Key types of accounts including assets, liabilities, capital, income and expenses.
4) The double-entry system where every transaction has two aspects involving debits and credits.
The accounting cycle refers to the complete sequence of accounting procedures that are repeated during each accounting period. It begins with recording transactions and ends with preparing financial statements. The key steps in the accounting cycle are: 1) analyzing transactions, 2) journalizing transactions, 3) posting to ledger accounts, 4) preparing a trial balance, and 5) preparing financial statements.
The document discusses the accounting cycle and provides examples of classifying accounts, journalizing transactions, preparing ledger accounts, and posting journal entries to the ledger. It begins by classifying various accounts as personal, real, or nominal. Examples are then provided of journalizing transactions and posting the journal entries to update the appropriate ledger accounts. The key steps in journalizing, preparing ledger accounts, and posting entries from the journal to the ledger are outlined. Compound or combined journal entries involving multiple debits and/or credits are also introduced.
The document describes the 7 stages of the accounting cycle. Stage 1 is the preparation of source documents. Stage 2 is the recording of transactions in journals. Stage 3 is the posting of journal entries to ledgers. Stage 4 is preparing a trial balance. Stage 5 is making adjustments. Stage 6 is closing accounts and preparing financial statements. Stage 7 is the preparation of the final accounts.
20 Effective Interview Questions for Accounting and Finance ProfessionalsRobert Half
The document lists 20 potential interview questions for accounting and finance professionals. The questions cover a range of topics including important skills for accountants, explaining complex processes, impacts of purchases on financial statements, defining big data, differences between accounts receivable and payable, journal entries, accounting software, developing business metrics, evaluating financial information, and recent changes in accounting standards.
Cholera is an infection of the small intestine caused by the bacterium Vibrio cholerae. The main symptoms are profuse watery diarrhea and vomiting, which can lead to rapid dehydration. Transmission is primarily through consuming contaminated drinking water or food infected with the Vibrio cholerae bacteria. Treatment involves oral rehydration solutions and antibiotics for severe cases.
Vibrio cholerae is a gram-negative bacterium that causes the disease cholera. It produces a toxin that binds to receptors on intestinal cells and causes severe diarrhea by promoting fluid secretion and inhibiting absorption. Cholera spreads through contaminated food and water and causes epidemics in areas with poor sanitation. Treatment focuses on oral rehydration to replace fluid losses. Prevention involves access to clean water, hygiene education, and possibly vaccination in endemic areas.
This document summarizes the epidemiology, pathogenesis, clinical presentation, diagnosis, and treatment of Campylobacter infection. Campylobacter is a common cause of bacterial diarrhea worldwide. It is often acquired through contaminated poultry or water and causes gastroenteritis. While usually self-limiting, it can occasionally lead to Guillain-Barre syndrome. Treatment involves rehydration and antibiotics like erythromycin to shorten the course of infection. Prevention focuses on food safety and water treatment.
Cholera is caused by the bacterium Vibrio cholerae which is typically spread through contaminated food or water. It causes severe diarrhea and dehydration. The classic symptoms include watery diarrhea, vomiting, and muscle cramps which can lead to severe dehydration within hours. The bacteria produce a toxin that increases cyclic AMP in intestinal cells, causing them to secrete fluids and electrolytes leading to diarrhea. Prevention focuses on proper disposal of infected waste and ensuring water and food are free from contamination. Treatment involves oral rehydration and antibiotics to kill the bacteria.
- Cholera is caused by the bacteria Vibrio cholerae, which produces a toxin that causes severe diarrhea and dehydration. It spreads through contaminated food and water.
- There have been 7 pandemics of cholera since 1817. Treatment focuses on oral rehydration therapy to replace fluid losses. Antibiotics can shorten the course of the disease. Prevention emphasizes access to clean water, sanitation, and vaccination in endemic areas.
Cholera is an acute diarrheal infection caused by the bacterium Vibrio cholerae found in contaminated food or water. John Snow discovered in the 19th century that cholera is spread through contaminated water. There have been seven pandemics since the 1800s that have killed millions. It is now endemic in many countries and spreads through waterborne and foodborne transmission. Symptoms include sudden onset of massive diarrhea and vomiting which can lead to dehydration and shock if fluid is not replaced. Prevention strategies include water purification, handwashing, proper food handling and cholera vaccines. Treatment involves oral rehydration salts or intravenous fluids for severe cases.
Current Understanding of the Transmission, Diagnosis, and Treatment of H. pyl...AI Publications
H. pylori infection is a prevalent bacterial infection that affects the gastric mucosa of humans, with a prevalence ranging from 30% to 90%, depending on the region. The infection is a significant cause of gastritis, peptic ulcer disease, and gastric cancer. In this comprehensive review, we discuss the current understanding of the transmission, diagnosis, and treatment of H. pylori infection. We describe the risk factors and epidemiology of the infection, along with its pathogenesis, which involves multiple virulence factors that contribute to the colonization and survival of the bacteria in the acidic stomach environment. Diagnostic tests for H. pylori infection include invasive and non-invasive methods, with the choice of test depending on several factors. Treatment of H. pylori infection is aimed at eradicating the bacteria and preventing complications. Antibiotic-based triple or quadruple therapy, in combination with acid-suppressing agents, is the standard treatment, but antibiotic resistance is an emerging problem that needs to be addressed. This comprehensive review provides a useful resource for clinicians, researchers, and public health officials involved in managing H. pylori infection and its associated complications.
This document summarizes fish-borne zoonotic diseases and focuses on vibriosis and cholera. It discusses how vibriosis is caused by the bacteria Vibrio aguillarum in fish and can cause human cholera. Cholera is an infectious disease transmitted through contaminated food or water and causes severe diarrhea that can lead to death by dehydration. The document traces the history of cholera pandemics and discusses the etiology, pathogenesis, clinical signs, treatment and prevention of both vibriosis in fish and cholera in humans.
This document discusses cholera, an acute diarrheal disease caused by the bacterium Vibrio cholerae. It provides definitions and terminology related to cholera, describes the history and epidemiology of the disease. Key points include that cholera spreads via contaminated food or water, symptoms include profuse watery diarrhea that can lead to dehydration and shock. Prevention strategies focus on access to clean water, sanitation, and oral cholera vaccines. Recent studies examined rapid diagnostic tests and strategies for preventing cholera outbreaks in India.
Emerging and re-emerging diseses part2 (INCLUDES ANTIMICROBIAL RESISTANCE)Dr. Mamta Gehlawat
2nd half of my ppt on emerging and re-emerging diseases. i uploaded the first half already. pls refer to that too. this ppt has info on AIDS/HIV, ZIKA, EBOLA-MARBURG, MELIODIOSIS, CHOLERA and ANTIMICROBIAL RESISTANCE
Cholera is a disease caused by the bacteria Vibrio cholerae that affects millions of people worldwide each year. It causes severe diarrhea and dehydration that can be life-threatening if not treated promptly. The disease spreads through contaminated food or water and proper sanitation and hygiene practices are important to prevent transmission. Treatment involves oral rehydration and antibiotics to kill the bacteria. Vaccines also exist to help prevent outbreaks.
Cholera is an infection of the small intestine caused by the bacterium Vibrio cholerae. It is characterized by severe watery diarrhea that can lead to dehydration and death if untreated. The lecture discusses the taxonomy, morphology, culture characteristics, pathogenicity and symptoms of V. cholerae. It also covers the modes of transmission, laboratory diagnosis, treatment using antibiotics and oral rehydration solution, and prevention through sanitation and hygiene measures.
Cholera is an infection of the small intestine caused by the bacterium Vibrio cholerae. It is characterized by severe watery diarrhea that can lead to dehydration and death if untreated. The lecture discusses the epidemiology, morphology, culture characteristics, pathogenicity and symptoms of V. cholerae. It also covers the laboratory diagnosis, treatment involving antibiotics and oral rehydration solution, and prevention through basic sanitation and hygiene measures.
The customer purchased an antique pocket watch from Etsy for their mother's day gift, but it did not arrive on time as promised. After following up with customer service, they were informed of shipping delays but the package still did not arrive as expected. Further inquiries also resulted in long wait times. Ultimately, the package was received damaged after multiple weeks of delay. While refund and return options were provided, the overall experience left the customer frustrated and dissatisfied with Etsy's service.
The document discusses gastrointestinal (GIT) diseases, specifically focusing on diarrheal diseases. It provides definitions and classifications of different types of diarrhea. It then discusses the major causes of infectious diarrhea including viruses (e.g. rotavirus), bacteria (e.g. E. coli, Salmonella), parasites (e.g. Giardia), and others. The document outlines the epidemiology, reservoirs, transmission, and risk factors. It summarizes WHO recommendations for treatment and prevention. Specific diseases like cholera and polio are also summarized in terms of etiology, epidemiology, and prevention/control strategies.
enumeration of bacteria from food borne vegetables (URBAS ASHIQ)Urbas Ashiq
Urbas Ashiq submitted a project report on enumerating bacteria from food-borne vegetables. The report discussed how bacteria commonly cause food poisoning due to improper food handling. It outlined several bacteria that often cause food-borne diseases like Campylobacter, Salmonella, E. coli, and norovirus. To prevent such diseases, the report recommended keeping food clean, separating raw and cooked food, storing food at safe temperatures, and using safe water. It also described treating food poisoning by replacing lost fluids and electrolytes.
Cholera and its Control measures (Gowtham 403 grp).pdfGowthamSelvaraj21
Cholera is an acute, highly transmissible intestinal infection caused by Vibrio cholerae bacteria. It is characterized by sudden onset of severe watery diarrhea that can lead to rapid dehydration and death if untreated. It is most commonly transmitted through contaminated drinking water or food. In 2020, over 300,000 cases and 800 deaths from cholera were reported globally. Control measures focus on access to clean water and sanitation, handwashing, food and household hygiene, oral cholera vaccination, and oral rehydration therapy for treatment. Surveillance of cases is also important for outbreak response.
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2. 2 J DIARRHOEAL DIS RES Mar 1999 Rabbani and Greenough III
the small intestine, stimulating massive outpouring of V. cholerae (8,11). Domestic freezing is usually
fluid and electrolytes and leading to severe watery ineffective in sterilizing foods, and the organisms can
diarrhoea, dehydration, vomiting, electrolyte survive for a long period in a frozen state.
abnormalities, and metabolic acidosis. Although the
Fruits and vegetables: In many countries, the practice
majority of infections with V. cholerae lead to inapparant
of fertilizing gardens with untreated night soil and the
infection or mild disease, death occurs in 50 to 70% of
habit of consuming uncooked vegetables have often
the severe cases if they are not adequately rehydrated
resulted in cholera outbreaks. Vegetables may be
(2), either by intravenous infusion or, more simply, by
contaminated during washing with polluted water. This
oral rehydration solutions (ORS) (3). Antimicrobial
can also occur when contaminated water is injected into
agents, including tetracycline, are effective in reducing
fruits, such as water melons, to preserve their weight
the volume of fluid loss and the duration of diarrhoeal
and taste (12). The pH of a specific fruit is an important
illness (4). Although cholera occurs in individuals of all
factor that influences contamination by V. cholerae. Sour
ages, children aged 2 to 9 years have the highest
fruits, such as lemons and oranges, with lower pH (below
incidence of the disease in endemic areas, such as
4.5) do not support the growth of V. cholerae, and, thus,
Bangladesh (5). Short-lived, protective immunity
do not pose risk of cholera transmission. Fruit pulp and
develops in adults in the endemic areas due to repeated
concentrate preserved in cans are also less likely to be
exposures to infection, but long-term protection is rare.
contaminated if they have an acidic pH. Spices, including
Cholera is a disease of great epidemic potential. It is raw onions and garlic, can support the survival of V.
endemic along the Ganges valley, particularly in eastern cholerae for 2 to 3 days at ambient temperature (8,13).
India and Bangladesh. Since 1817, six cholera pandemics
Seafoods: The importance of fish and shellfish as a
have swept over the world, exacting a heavy toll of
vehicle of transmission of cholera has been recognized
human lives. The seventh pandemic started in Sulawesi,
by early observers. Fishes are likely to be contaminated
Indonesia in the early 1960s, and has now spread to most
by V. cholerae when the surrounding water is
parts of the world. This last pandemic was the first caused
contaminated by sewage or other environmental sources
by the El Tor biotype of V. cholerae.
of V. cholerae O1. It has been shown that V. cholerae
can survive in seawater in association with zooplankton
Epidemiological evidence indicates that cholera is
(copepods). Zooplankton secrete a self-protective coat
primarily a water-borne disease (6). Its faecal-oral
of chitin that can be dissolved by chitinase, an enzyme
transmission usually occurs by the ingestion of faecally
produced by V. cholerae O1. Seafoods, including
contaminated water by susceptible individuals. Besides
molluscs, crustaceans, crabs, and oysters, feed on
drinking water, food has also been recognized to be an
plankton and can become infected with V. cholerae (14).
important vehicle of transmission of cholera. In
Once infected, particularly clams and oysters can harbour
developing countries, where both poverty and poor
V. cholerae for weeks, even if refrigerated (7). In crabs,
sanitation are common, faecal contamination of domestic
the organisms can rapidly multiply at ambient
and commercial food is likely to occur, and in many
temperature, and boiling for less than 10 minutes or
outbreaks the infection has been traced to consumption
steaming for less than 30 minutes does not completely
of faecally-contaminated foods. In the developed
kill V. cholerae (7).
countries, food-borne outbreaks of cholera have on many
occasions occurred due to consumption of contaminated Dairy products: V. cholerae O1 can survive for more
seafoods. than two weeks in different dairy products, including
milk, milk products, soft deserts, and cakes. Addition of
FOOD AS A MEDIUM FOR SURVIVAL sugar and eggs enhances bacterial survival. Although V.
cholerae is killed by pasteurization of milk, the
OF V. CHOLERAE
organisms can persist in raw milk as long as four weeks,
The survival and growth of V. cholerae in foods depend even if refrigerated (13).
on the physico-chemical properties of the particular
Poultry and meat: Contamination of meat of animal
foodstuff that has been contaminated. Food
origin occurs exogenously during processing, cooking,
characteristics, which enhance the growth of V. cholerae,
storage, or consumption. It has been shown that V.
are low temperature, high-organic content, neutral or
cholerae can live and grow on cooked chicken, an
alkaline pH, high-moisture content, and absence of other
increase in numbers of V. cholerae from 103 to 106 within
competing micro-organisms in the food (7-10). V.
16 hours has been demonstrated (15). An early
cholerae are very sensitive to heat, and are rapidly killed
when exposed to temperature of 100 oC. Drying and observation by Seligmann indicates that consumption
of improperly cooked horsemeat was incriminated in a
exposure to sunlight is also an effective means of killing
3. 3
Food as a vehicle of transmission of cholera
small outbreak of cholera in Berlin in 1918 (16). The procedures should be employed for the isolation and
meat had been prepared by an infected butcher who characterization of V. cholerae. Specific guidelines for
succumbed to cholera the next day. laboratory examination of contaminated foodstuff,
developed by the U.S. Food and Drug Administration,
There are many other types of food that may be
Department of Public Health, may be useful for proper
contaminated with V. cholerae. V. cholerae can survive
identification of the suspected pathogens.
on cooked rice, potatoes, eggs, and pasta for up to 5
days, and can also survive in spices, including pepper
and cinnamon, for up to several days (8). EPIDEMIOLOGY OF FOOD-BORNE
TRANSMISSION OF CHOLERA
LABORATORY CHARACTERIZATION
The epidemiological evidence reviewed by Politzer (20)
OF V. CHOLERAE O1
suggests drinking water as the primary vehicle of
transmission of cholera. However, early observations as
The mere presence of V. cholerae in food does not
well as those made during the last 30 years indicate that
implicate food as the vehicle of cholera transmission.
many outbreaks of cholera have been traced to
The organism must be tested in the laboratory to identify
consumption of contaminated foods throughout the
its biological characteristics with regard to pathogenicity,
world (21,22). The role of food as a vehicle of cholera
toxin production, antigenic type, and genetic structure.
transmission depends on several factors, including the
Application of modern molecular techniques to detect
likelihood of contamination of a specific food item, and
V. cholerae in food samples should be considered. the gastric acid-neutralizing capacity of a particular food.
Table 1. Food-borne outbreaks of cholera mostly in countrie other than USA*
Country Year Infected food References
Philippines 1961 Raw shrimps 26
Malaysia 1963 Seafood/shellfish 36
Israel 1970 Raw vegetables 44
Bahrain/Sydney 1972 Hors d’oeuvres 46
Italy 1973 Mussels 37
Portugal 1974 Raw cockles/bottled water 39/59
Guam 1974 Salted fish 60
Gilbert Island 1977 Raw shellfish/salted fish 61/62
Louisiana, USA 1980 Inadequately steamed crabs 63
Sardinia 1980 Shellfish 35
Singapore 1982 Seafood 33
Gulf of Mexico 1983 Water-contaminated rice 42
Micronesia 1984 Food 64
*Reproduced with permission
Molecular probes of natural DNA fragments (17,18) and
Seafood and shellfish: Seafoods, particularly fish and
synthetic oligonucleotides have been developed to detect shellfish, have been incriminated in many cholera
V. cholerae toxin genes (19). Polymerase chain reaction outbreaks since the nineteenth century (Table 1). Fish
(PCR), a very sensitive tool, can detect trace amounts of becomes infected with V. cholerae either due to sewage
DNA fragments, even from dead or lysed organisms. contamination of water or by ingestion of aquatic
This assay may be very useful in investigating food- vegetation and zooplankton infested with V. cholerae
borne cholera outbreaks. Epidemiologic and medical (23). In a food survey in Taiwan, 1,088 vibrios, including
V. cholerae and other species, were isolated from
implications should be considered to establish the cause-
seafoods and aquacultured foods (24). In many countries,
and-effect relation between the suspected source of
fish is eaten raw or undercooked (25,26). Outbreaks of
infection and the outbreak of the disease. In this regard,
cholera due to consumption of raw fish have been
the laboratory plays an important role with respect to
reported from Japan as early as 1886 (27) and from the
characterization of the organism. When a specific food
Philippines in 1908 (28). Fish may serve as an important
is suspected for contamination, a sufficient amount (25
vehicle of transmission of cholera in the endemic areas
g) of the food should be sampled, and specific laboratory
4. 4 J DIARRHOEAL DIS RES Mar 1999 Rabbani and Greenough III
of Asia, where it is a major food item and is likely to be was isolated from 42% of shellfish tested, and
contaminated by V. cholerae due to both poor consumption of raw or poorly cooked cockles were
environmental sanitation and poverty prevailing in this significantly associated with cholera cases.
region. Pandit and Hora (29) observed that, in India, the
Reports of cholera outbreaks from the U.S. Gulf
transmission of endemic cholera is maintained through
Coast during the last two decades provide
infection of hilsa fish, which breeds abundantly in the epidemiological evidence of a definitive role of fish in
Hoogly river that runs through Calcutta. the transmission of cholera (Table 2). In the United
States, the first case of cholera after 1911 occurred in a
During the course of the seventh cholera pandemic,
shrimp fisherman in Texas in 1973 (40). The isolate was
contaminated seafoods have been identified as the source
identified as V. cholerae O1, biotype El Tor. In spite of
of infection in several outbreaks. Seafoods and seafood
extensive investigations, the source of infection remained
products most frequently incriminated are raw shrimps,
unidentified. Later, in 1978, 11 persons were attacked
crabs, oysters, clams, shellfish, and mussels. These foods
with V. cholerae El Tor in Louisiana after eating cooked
have been identified as a source of repeated outbreaks
crabs in different sites of the coastal marshes. In 1984
in the Unites States and elsewhere (30-32). In 1978,
in Maryland, one person who had consumed infected
Singapore experienced another cholera outbreak, which crabs collected along the Texas coast developed cholera
was traced to consumption of prawns and squid, which (41). In Florida (25) and Georgia (26), two isolated cases
were likely to be contaminated by infected food handlers of cholera occurred in 1978 due to consumption of
(34). Again in Singapore, a food-borne cholera outbreak contaminated raw oysters. In the 1986 Louisiana cholera
occurred in 1982 among 37 construction workers after outbreak, 18 persons were attacked in 12 different
Table 2. Cholera cases in the Unites States associated with consumption of seafoods from Gulf Coast waters (1973-
1992)*
State Year No. of cases Implicated food References
Texas 1973 1 Raw oysters 40
Louisiana 1978 11 Cooked crabs 63
Texas 1981 2 Fish/shrimps 65
Texas 1981 16 Cooked rice 53
Maryland 1984 1 Crabs 41
Florida 1986 1 Raw oysters 25
Louisiana 1986 18 Crabs/shrimps 63
Georgia 1986 18 Raw oysters 26
Louisiana 1987 2 Crabs 31
Colorado 1988 1 Raw oysters 66
Total 1973-1992 71
*Reproduced with permission
clusters; all were infected by eating crabs and shrimps
they ate contaminated seafoods at a local cafeteria, where collected from different sites along the Louisiana coast
two food handlers were found to be infected with V. (32). In the fall of 1991, a single cholera case was
cholerae O1 (33). In 1979, an outbreak of cholera identified in an oil rig barge in Texas, which was
occurred in Sardinia; the source of infection was traced followed by 13 secondary cases of cholera and one
to eating of bivalves from which V. choleare O1 were asymptomatic infection (42). The source of infection in
isolated (35). In 1974 in the Pacific island of Guam, the index case was traced to consumption of infected
seafoods from local water. The secondary cases were
eating of small, salted fish was thought to be the vehicle
infected by consuming rice prepared with water
of transmission of cholera (60).
contaminated by the faeces of the index case through
The importance of shellfish as a vehicle of cholera cross-connection between a sewer drain and the drinking
transmission has been conclusively shown by a water supply. Since 1973, a total of 65 cholera cases
statistically significant association of cholera with have been associated with the Gulf Coast reservoir in
shellfish consumption in Italy in 1973 (37,38). One year the United States. In all cases, the V. cholerae O1 isolated
later, a severe cholera epidemic occurred in Portugal with were of El Tor biotype and Inaba serotype; all strains
2,467 reported cases and 48 deaths (39). V. cholerae O1 produced cholera toxin and haemolysin on blood agar,
5. 5
Food as a vehicle of transmission of cholera
and possessed a characteristic bacteriophage, VcA3 (19). epidemic could not establish a source of infection for
Genetically, all strains had the same restriction digestion the initial cases. However, the later cases were shown to
pattern and ribotype pattern. All these data support the be infected by secondary spread of V. cholerae through
hypothesis that V. cholerae O1 strains have been consumption of vegetables contaminated by faeces from
persisting as a free-living organism along the Gulf Coast the initial cases. In Jerusalem, vegetables are supplied
water for the last 20 years, independent of exogenous from the surrounding villages, where sewage and night
introduction during the pandemics. soil are used as fertilizer.
Other foods. The African continent had been free of In the United States, an outbreak of cholera occurred in
cholera for 70 years, but in 1971 cholera reappeared in Maryland in 1991, in which four persons were infected,
Africa, and 30 of the 46 countries started reporting three of them having diarrhoea (45). Consumption of
cholera. During a cholera outbreak in Mali in 1984, a Thai-style rice topped with coconut milk was the source
Table 3. U.S. cases of cholera in persons returning from Latin America or eating food from
Latin America.*
State Year Nos. of cases Suspected food Country of food origin References
Georgia 1991 1 Cooked crab meat Peru 67
New Jersey 1991 8 Cooked crab/salad Ecuador 68
Florida 1991 1 Raw oysters Ecuador 68
New York 1991 4 Cooked crab/salad Ecuador 69
New Jersey 1991 1 Crabs Ecuador CDC, Unpub.
California 1992 2 Seafood at stand El Salvador CDC, Unpub.
California 1992 76 Shrimp/fish in salad Peru 53
California 1992 1 Raw seafood El Salvador CDC, Unpub.
Total 1991-1992 94
*Reproduced with permission
case-control study showed that eating leftover millet of infection. Laboratory examination of the same brand
gruel by villagers in an arid region was associated with of coconut milk revealed its contamination by V.
cholera (43). In this community, millet is a major food choleare, which differed in molecular characteristics
item, which is prepared once a day and stored at room from those strains causing the seventh pandemic in Asian
temperature for many hours and is often consumed and Latin American countries, and in the Gulf Coast of
without proper cleanliness by people in groups. In the U.S.A. These findings suggest that the coconut milk
another outbreak in Guinea, consumption of leftover rice was contaminated during its preparation in the country
with peanut sauce has been incriminated as the vehicle of origin.
of transmission of cholera. In contrast, leftover rice eaten
An outbreak of cholera was reported in 47 of the
with tomato sauce, having an acidic pH, unfavourable
331 passengers of an airline flight en route from London
for V. cholerae, was not associated with cholera cases
to Sydney in 1972. The source of the infection was traced
(43). There were also two reports of cholera outbreaks
to consumption of contaminated hors d’oeuvre served
due to contamination of rice during preparation of a
on the aircraft and obtained from a caterer in Bahrain,
funeral feast by women who had cleaned the bodies of
where an epidemic of cholera was going on (47).
patients who died of cholera.
Recent cholera outbreaks in Latin America: For the
The importance of contaminated vegetables as a
first time in the 20th century, cholera appeared in Latin
vehicle of cholera transmission is indicated by an
America in 1991. Peru was the first country to report
outbreak in Jerusalem (44). In August 1970, an epidemic
cholera during the epidemic (48). The disease spread
of cholera broke out in Jerusalem with 256 cases, the
quickly to other countries. By August 26, 1992, 640,000
initial cases appearing simultaneously in three different
cholera cases and 5,600 deaths were reported by 19
places. However, the later cases appeared sporadically
countries (48-50); these numbers were more than those
without specific primary cases; and the cases were
reported for the entire world during the former five years
limited to the Jerusalem region, despite considerable
(51,52). In the same wave of the epidemic, cholera
movement of people. Careful investigation of the
6. 6 J DIARRHOEAL DIS RES Mar 1999 Rabbani and Greenough III
entered into the United States with travellers returning Coast, Africa, Latin America), in the endemic areas of
from Latin America (Table 3). Food has been India and Bangladesh, fish-borne transmission seems to
incriminated as the vehicle of transmission of cholera be rare. In these communities, most people eat fresh
from Latin America to the United States in several water fish rather than salt water fish and other marine
instances. species, such as shellfish, clams, and oysters.
Nevertheless, V. cholerae O1 has been isolated from
An index case of cholera was identified in New York
aquatic flora and fauna in this region (55). It has also
in 1991. This case was followed by three secondary cases
been found that blue-green algae can act as a reservoir
of symptomatic infection with V. cholerae O1 (69). The
of V. cholerare O1 in the aquatic environment of
index case had travelled to Ecuador and brought with
Bangladesh (55). These algae are eaten by fish. Since
him boiled crabs which were found to be contaminated
fish is usually well-cooked before eating and never
by the V. cholerae strain prevailing in Latin America, as
consumed raw, fish-borne infections must be rare.
detected by sensitive assays, including PCR and DNA
However, cross contamination of foods through handling
ribotyping (42). The molecular characteristics of this
of infected fish remains a possible risk of transmission.
strain of V. cholerae O1 were completely different from
those isolated from the coastal areas of Texas and In endemic areas, transmission of cholera through
Louisiana. In another instance in 1991, 76 airline contaminated foods served by street vendors and
passengers returning from Argentina to Los Angeles restaurants should be considered. In Dhaka, the capital
were infected with V. cholerae O1 by eating city of Bangladesh, there were two outbreaks of cholera
contaminated shrimp and fish salads prepared in Lima, in 1974 and 1975 (56). The results of a case-control study
Peru (53). Although no secondary spread occurred, 37 indicated that the attack rates of cholera were
passengers became ill, and of them one died. A total of significantly associated with eating in restaurants.
41 imported cases of cholera have been documented in Moreover, the free food distribution centres established
the United States during 1961-1990. Most of these cases in the city to feed the famine-affected people also played
were associated with travel to Latin American countries a significant role in the transmission of the disease. In
or with eating of seafoods brought from there. the Hong Kong outbreak of cholera in 1990, the source
of infection has been traced to consumption of a special
These observations indicate that there is a possibility
rice dish called “moonsalus” (57).
of cholera transmission through eating contaminated
food in another country. However, the risk of
transmission of cholera through imported commercial CONCLUSIONS AND RECOMMENDATIONS
foods seems to be small. There have been no cases of
Cholera is a disease of great public health importance.
cholera in the United States as a result of importing
The mainstay of treatment of cholera is the replacement
commercial foodstuffs from Latin American countries.
of fluid and electrolytes lost in the stools. Rehydration
can be easily achieved either by intravenous infusions
FOOD-BORNE CHOLERA or more simply by oral rehydration solutions. Treatment
IN ENDEMIC REGIONS with an effective antimicrobial agent reduces fluid loss
and the duration of diarrhoea, but this form of treatment
In cholera endemic regions of Asia, including
is not considered a substitute for rehydration therapy.
Bangladesh, contamination of food may be an important
Since untreated diarrhoeal stools from cholera patients
factor in the transmission of cholera. Case-control studies
are the primary source of environmental contamination,
have shown that, in Bangladesh, the rate of
including water sources and foods, proper treatment of
contamination of household water with V. cholerae O1
cholera cases and safe disposal of faeces would reduce
is significantly higher in water used for cooking than in
secondary spread and faecal contamination of the
water used for drinking (54). It is likely that water may
environment. Transmission of cholera occurs by the
serve as a source of secondary contamination of food
faecal-oral route, and water has been recognized as the
during its preparation. A household survey carried out
primary vehicle of cholera transmission. Thus, to
in Bangladesh indicates that only 0.13% of the food
interrupt the transmission cycle, effective public health
samples cultured were contaminated with V. cholerae measures should be undertaken to prevent faecal
O1. This indicates that the risk of food-borne contamination of drinking water supplies, as well as to
transmission of cholera during the non-epidemic season establish sanitary disposal and sewage treatment systems.
in the endemic areas may be small. Although fish and This is not an easy task in most situations, and, thus,
shellfish have been shown to be an important vehicle of calls for a considerable investment and commitment by
cholera transmission in non-endemic areas (U.S. Gulf the government and the community leaders.
7. 7
Food as a vehicle of transmission of cholera
National Institutes of Health, New England Medical Center,
Beside water, foods constitute an important vehicle for
Northfield Laboratories, and Walter Reed Army Institute for
transmission of cholera in the environment.
Research-USA; universities: Johns Hopkins University,
Consumption of V. cholerae-contaminated foods, Karolinska Institute, Loughborough University, London School
particularly seafoods and fish, has been implicated in a of Hygiene & Tropical Medicine, University of Alabama at
large number of cholera outbreaks throughout the world. Birmingham, University of Goteborg, University of Maryland,
Seafoods can be infected if the surrounding water is University of Newcastle, University of Pennsylvania, and
faecally contaminated or during its processing by the University of Virginia; others: Abt. Associates Inc., ALICO,
Arab Gulf Fund, American Express Bank, ANZ Grindlays
infected food handlers. After cooking, food can be
Bank, British Geological Survey, Cairn Eergy Plc., Cytos
infected during storage and consumption in an unclean
Pharmaceuticals LLC, Department of Defence-USA, Family
environment. Health International, Helen Keller International, Macro
International Inc., National Vaccine Programme-USA,
To prevent food-borne transmission of cholera, the
Occidental of Bangladesh Ltd., Proctor Gamble, Rand
foods must be safe and free from V. cholerae before
Corporation, Rhone-Poulenc Rorer, Save the Children Fund-
consumption. The World Health Organization USA, Shell Bangladesh Exploration & Dev. B.V., UCB
recommends the following food safety measures to Osmotics Ltd., Urban Family Health Programme, UNOCAL,
prevent the spread of cholera (58): and Wander A.G. The authors acknowledge the support
• avoid raw food (exception: undamaged fruits and received from Prof. R. Eeckels, M. Shamsul Islam Khan, and
Dr. M. Bennish.
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