This document reviews traditional and new diagnostic and therapeutic options for canine and feline ureteral obstructions. Ureteral obstructions are commonly caused by ureteral stones or tumors and can be difficult to diagnose and treat. Newer minimally invasive techniques such as ureteral stenting, lithotripsy, and percutaneous nephrostomy tube placement are gaining acceptance and provide alternatives to traditional open surgeries. These techniques aim to simultaneously diagnose and treat obstructions in an expedited and less invasive manner.
Endoscopic ultrasound (EUS)-guided biliary interventions can be performed when endoscopic retrograde cholangiopancreatography (ERCP) fails or is not possible due to inaccessible papilla. Various EUS biliary drainage techniques exist with similar success rates but different risks of complications. EUS allows biliary access and stent placement via multiple routes without needing to access the papilla. The procedure involves using EUS to puncture and access the desired bile duct, placing a guidewire, dilating the tract if needed, and placing plastic or metal stents under endoscopy and fluoroscopy guidance. Success rates are high but risks include bleeding, bile leaks, cholangitis, and stent issues.
This document discusses urinary tract obstruction, specifically ureteropelvic junction obstruction (UPJO). It covers the causes, evaluation, and surgical treatment options for UPJO, with a focus on laparoscopic pyeloplasty. Key points include that UPJO can be congenital or acquired, and indications for intervention include symptoms, impaired renal function, stones or infection. Laparoscopic pyeloplasty is a less invasive alternative to open surgery that provides comparable success rates while reducing morbidity. The procedure involves mobilizing the colon, dissecting the ureter, and performing a dismembered pyeloplasty reconstruction.
This study evaluated the safety and efficacy of percutaneous nephrolithotomy (PCNL) guided solely by ultrasonography in over 700 cases over 5 years. Access to the pelvicalyceal system was successful in all cases using ultrasonography. The overall stone-free rate was 87.4% and complications were minor, with a low 16% rate. The study demonstrated that PCNL can be performed safely and effectively using only ultrasonography guidance, avoiding the risks of radiation exposure from fluoroscopy.
Dr Pawan Sharma1*, Dr D K Verma2, Dr Raj Kumar3
1General Surgeon Incharge, Civil Hospital Rohru, Shimla (HP), India
2Professor of Surgery, IGMC Shimla (HP), India
3General Surgeon Incharge, Distt Hospital Bilaspur (HP), India
*Address for Correspondence: Dr. Pawan Sharma, General Surgeon Incharge, Department of Surgery, Civil Hospital,
Rohru, Shimla, HP, India
Received: 17 September 2016/Revised: 11 October 2016/Accepted: 25 October 2016
ABSTRACT- This study was carried out to evaluate laparoscopic retroperitoneal ureterolithotomy (RPUL) as a viable
option to open surgical ureterolithotomy, laparoscopic transperitoneal ureterolithotomy (TPUL) & endoscopic urology and
to assess its place in the spectrum of alternatives for the surgical treatment of ureteric calculi in a tertiary care centre. This
study was conducted on 20 selected patients of single large impacted calculus of size more than 8mm in upper & middle
ureter. It was observed that excessive bleeding was present in only one (5%) of the patients, while need for conversion to
open ureterolithotomy was seen in 8 (40%) cases. No major peri-operative complications were encountered. From our
experience, it can be concluded that this procedure has definitely shown decreased post-operative discomfort, decreased
requirement of post-operative analgesia, better cosmesis, early return to work and less morbidity. RPUL can be considered
as another well-established armamentarium in the armour of laparoscopic surgeons and is recommended as an effective
minimally invasive primary treatment in large, impacted difficult stones in the upper & mid ureter.
Key-words- Retroperitoneal ureterolithotomy (RPUL), Transperitoneal ureterolithotomy (TPUL), Extracorporeal
shockwave lithotripsy (ESWL)
ABSTRACT- Urinary tracts stone diseases are one of the most common afflictions of modern society and it has
witnessed much advancement in its management. Keeping in view various aspects of management we carried out a
comparatively newer study called Transperitoneal Ureterolithotomy. This study was carried out to evaluate Laparoscopic
Transperitoneal Ureterolithotomy (TPUL) as a viable option to open surgical ureterolithotomy, Laparoscopic
Retroperitoneal Ureterolithotomy (RPUL) & endoscopic urology and to assess its place in the spectrum of various surgical
interventions for ureteric calculi in a tertiary care center. This study was conducted on 25 selected patients of a single large
impacted calculus of size more than 10mm in upper and middle ureter. It was observed that conversion to open
ureterolithotomy was observed in 4 cases and excessive bleeding in one case. No major perioperative complications were
seen. The procedure has definitely shown decreased post-operative discomfort, decreased requirement of post-operative
analgesia, better cosmesis, early return to work and less morbidity.
Key-words- Transperitoneal ureterolithotomy (TPUL), Retroperitoneal ureterolithotomy (RPUL), Extracorporeal
shockwave lithotripsy (ESWL), Open surgical ureterolithotomy
PUJ obstruction is a restriction of urine flow from the renal pelvis to the ureter. It can be congenital or acquired, with congenital being one of the most common causes of antenatal hydronephrosis. Diagnosis involves ultrasonography, VCUG, diuretic renography and other imaging modalities to determine severity and presence of associated issues. Treatment depends on severity but typically involves surgical intervention like open or laparoscopic pyeloplasty to resect and reanastomose the obstructed segment if drainage is significantly impaired or renal growth is poor. Postoperative follow up with imaging is important to monitor repair.
This retrospective study evaluated 26 dogs that underwent fluoroscopic wire-guided nasojejunal tube placement between 2006 and 2010. The primary diagnosis in 60% of dogs was pancreatitis. The technique involved passing a wire through the nose and stomach to guide placement of a feeding tube in the jejunum. Transpyloric passage was achieved in 92.3% of dogs and jejunal access in 78.2% overall. Success at jejunal placement improved over time, with 100% success in the later half of the study. Complications included mild bleeding in 2 dogs and tube migration in 2 dogs due to sneezing. The median feeding duration was 3.3 days. This technique provides a minimally invasive
Evaluation of Obstructive Uropathy with Computed Tomography Urography and Mag...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Endoscopic ultrasound (EUS)-guided biliary interventions can be performed when endoscopic retrograde cholangiopancreatography (ERCP) fails or is not possible due to inaccessible papilla. Various EUS biliary drainage techniques exist with similar success rates but different risks of complications. EUS allows biliary access and stent placement via multiple routes without needing to access the papilla. The procedure involves using EUS to puncture and access the desired bile duct, placing a guidewire, dilating the tract if needed, and placing plastic or metal stents under endoscopy and fluoroscopy guidance. Success rates are high but risks include bleeding, bile leaks, cholangitis, and stent issues.
This document discusses urinary tract obstruction, specifically ureteropelvic junction obstruction (UPJO). It covers the causes, evaluation, and surgical treatment options for UPJO, with a focus on laparoscopic pyeloplasty. Key points include that UPJO can be congenital or acquired, and indications for intervention include symptoms, impaired renal function, stones or infection. Laparoscopic pyeloplasty is a less invasive alternative to open surgery that provides comparable success rates while reducing morbidity. The procedure involves mobilizing the colon, dissecting the ureter, and performing a dismembered pyeloplasty reconstruction.
This study evaluated the safety and efficacy of percutaneous nephrolithotomy (PCNL) guided solely by ultrasonography in over 700 cases over 5 years. Access to the pelvicalyceal system was successful in all cases using ultrasonography. The overall stone-free rate was 87.4% and complications were minor, with a low 16% rate. The study demonstrated that PCNL can be performed safely and effectively using only ultrasonography guidance, avoiding the risks of radiation exposure from fluoroscopy.
Dr Pawan Sharma1*, Dr D K Verma2, Dr Raj Kumar3
1General Surgeon Incharge, Civil Hospital Rohru, Shimla (HP), India
2Professor of Surgery, IGMC Shimla (HP), India
3General Surgeon Incharge, Distt Hospital Bilaspur (HP), India
*Address for Correspondence: Dr. Pawan Sharma, General Surgeon Incharge, Department of Surgery, Civil Hospital,
Rohru, Shimla, HP, India
Received: 17 September 2016/Revised: 11 October 2016/Accepted: 25 October 2016
ABSTRACT- This study was carried out to evaluate laparoscopic retroperitoneal ureterolithotomy (RPUL) as a viable
option to open surgical ureterolithotomy, laparoscopic transperitoneal ureterolithotomy (TPUL) & endoscopic urology and
to assess its place in the spectrum of alternatives for the surgical treatment of ureteric calculi in a tertiary care centre. This
study was conducted on 20 selected patients of single large impacted calculus of size more than 8mm in upper & middle
ureter. It was observed that excessive bleeding was present in only one (5%) of the patients, while need for conversion to
open ureterolithotomy was seen in 8 (40%) cases. No major peri-operative complications were encountered. From our
experience, it can be concluded that this procedure has definitely shown decreased post-operative discomfort, decreased
requirement of post-operative analgesia, better cosmesis, early return to work and less morbidity. RPUL can be considered
as another well-established armamentarium in the armour of laparoscopic surgeons and is recommended as an effective
minimally invasive primary treatment in large, impacted difficult stones in the upper & mid ureter.
Key-words- Retroperitoneal ureterolithotomy (RPUL), Transperitoneal ureterolithotomy (TPUL), Extracorporeal
shockwave lithotripsy (ESWL)
ABSTRACT- Urinary tracts stone diseases are one of the most common afflictions of modern society and it has
witnessed much advancement in its management. Keeping in view various aspects of management we carried out a
comparatively newer study called Transperitoneal Ureterolithotomy. This study was carried out to evaluate Laparoscopic
Transperitoneal Ureterolithotomy (TPUL) as a viable option to open surgical ureterolithotomy, Laparoscopic
Retroperitoneal Ureterolithotomy (RPUL) & endoscopic urology and to assess its place in the spectrum of various surgical
interventions for ureteric calculi in a tertiary care center. This study was conducted on 25 selected patients of a single large
impacted calculus of size more than 10mm in upper and middle ureter. It was observed that conversion to open
ureterolithotomy was observed in 4 cases and excessive bleeding in one case. No major perioperative complications were
seen. The procedure has definitely shown decreased post-operative discomfort, decreased requirement of post-operative
analgesia, better cosmesis, early return to work and less morbidity.
Key-words- Transperitoneal ureterolithotomy (TPUL), Retroperitoneal ureterolithotomy (RPUL), Extracorporeal
shockwave lithotripsy (ESWL), Open surgical ureterolithotomy
PUJ obstruction is a restriction of urine flow from the renal pelvis to the ureter. It can be congenital or acquired, with congenital being one of the most common causes of antenatal hydronephrosis. Diagnosis involves ultrasonography, VCUG, diuretic renography and other imaging modalities to determine severity and presence of associated issues. Treatment depends on severity but typically involves surgical intervention like open or laparoscopic pyeloplasty to resect and reanastomose the obstructed segment if drainage is significantly impaired or renal growth is poor. Postoperative follow up with imaging is important to monitor repair.
This retrospective study evaluated 26 dogs that underwent fluoroscopic wire-guided nasojejunal tube placement between 2006 and 2010. The primary diagnosis in 60% of dogs was pancreatitis. The technique involved passing a wire through the nose and stomach to guide placement of a feeding tube in the jejunum. Transpyloric passage was achieved in 92.3% of dogs and jejunal access in 78.2% overall. Success at jejunal placement improved over time, with 100% success in the later half of the study. Complications included mild bleeding in 2 dogs and tube migration in 2 dogs due to sneezing. The median feeding duration was 3.3 days. This technique provides a minimally invasive
Evaluation of Obstructive Uropathy with Computed Tomography Urography and Mag...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
The role of ercp in diseases of the biliary tract and pancreasThorsang Chayovan
This document provides guidelines from the American Society for Gastrointestinal Endoscopy (ASGE) on the role of endoscopic retrograde cholangiopancreatography (ERCP) in diseases of the biliary tract and pancreas. It was developed using an evidence-based methodology including a literature review. The guidelines are intended to apply to all physicians performing GI endoscopy. ERCP is described as useful for diagnosing and treating conditions like gallstones, biliary strictures, pancreatic disease, and leaks or injuries to the biliary tract. Outcomes of ERCP for various conditions are discussed along with appropriate patient selection and techniques.
A presentation about Intravenous Urography (Also known as Intravenous Pyeography).
The presentation contains 41 slides, and is divided into 4 parts :
1 - Introduction.
2 - The procedure.
3 - Examples for abnormal findings.
4 - Studies comparing IVU accuracy with KUB & USG with CT Scan.
This presentation was prepared and presented by me in the tutorials of the Radiology Department of Sebha Medical Center.
Ivu is a radiological investigation for visualization and assessment of the urinary tract.This presentation covers brief anatomy of urinary tract, indication and contraindication,contrast media dose and administration, routine and modified ivu procedure,its complication,ctivu and some abnormalities in the urinary tract.
Litotrissia percutanea laparoscopica nel rene pelvico casi cliniciMerqurio
This document describes a novel technique of laparoscopically assisted percutaneous pyelolithotomy for treating kidney stones in pelvic kidneys. The technique was used in 3 patients with large pelvic kidney stones who were not suitable candidates for standard percutaneous or laparoscopic approaches. The procedure involves using laparoscopy to expose the renal pelvis, then inserting a needle percutaneously into the pelvis under direct visualization. The tract is dilated and a nephroscope is used to remove stones without needing to incise or suture the pelvis. This approach provides direct access to the pelvis without risks of standard percutaneous or laparoscopic techniques. All 3 patients were successfully treated with no complications and no
This study evaluated 59 cats that underwent perineal urethrostomy surgery for feline lower urinary tract disease (FLUTD) at a university veterinary clinic. Early complications within 4 weeks of surgery occurred in 25.4% of cats, most commonly urethral stricture formation. Late complications after at least 4 months included recurring urinary tract infections in 28.2% of cats. Despite frequent complications, 32.2% of cats had no long-term issues, though recurring FLUTD symptoms still occurred in 23% of cats. Overall, the surgery provided a good quality of life for most cats, according to their owners.
UPJ obstruction is most commonly caused by intrinsic stenosis of the proximal ureter. It occurs in approximately 1 in 500 live births, with males and left kidneys more commonly affected. Ultrasound is used to diagnose and monitor hydronephrosis, while diuretic renography can determine if obstruction is present and assess renal function. Surgical correction via pyeloplasty is indicated if renal function is impaired or decreasing, with the Anderson-Hynes dismembered pyeloplasty being the most common procedure performed. Non-operative management with antibiotics may be appropriate if drainage is adequate on functional studies.
- The document presents updated national clinical guidelines for managing palatally ectopic maxillary canines from the Faculty of Dental Surgery at the Royal College of Surgeons of England.
- It describes five treatment strategies supported by levels of evidence: interceptive extraction of the deciduous canine, surgical exposure and orthodontic alignment, surgical removal of the ectopic canine, autotransplantation, and observation with no active treatment.
- The guidelines emphasize the importance of early diagnosis and management of ectopic canines to avoid complex treatment, damage to adjacent teeth, and potential litigation issues from treatment delays.
Long-Term Outcomes of Endoscopic Treatment for Bile Duct Stones in Patients A...JohnJulie1
This study evaluated long-term outcomes of endoscopic treatment for bile duct stones in 211 patients aged 85 years or older. Patients underwent either complete stone removal (group C, n=148) or incomplete stone removal with stent insertion (group I, n=63). Group I had a significantly higher proportion of patients with dementia. Complete stone removal had a longer procedure time but removed significantly smaller stones. Overall survival was significantly higher in group C, but disease-specific survival was similar between groups. The study concluded that endoscopic treatment can be safely performed in elderly patients and advanced age should not preclude complete stone removal.
Long-Term Outcomes of Endoscopic Treatment for Bile Duct Stones in Patients A...JapaneseJournalofGas
This study evaluated long-term outcomes of complete endoscopic stone removal versus incomplete stone removal with stent placement in 211 elderly patients aged 85 years or older with bile duct stones. Patients who underwent complete stone removal had a significantly higher overall survival rate but similar disease-specific survival rate compared to those who underwent incomplete stone removal. The proportion of patients with dementia was higher in the incomplete removal group. Complete stone removal can be safely performed in elderly patients, and advanced age should not preclude attempting full stone clearance.
Endoscopic retrograde cholangiopancreatography (ERCP) is an invasive procedure used to diagnose and treat pancreatic and biliary diseases. While it provides both diagnostic and therapeutic benefits, complications can occur in approximately 5-10% of cases. The most common complication is pancreatitis, occurring in 3-5% of cases, which usually causes abdominal pain and nausea but resolves within a few days. Other potential complications include perforation, bleeding, cholangitis, and cholecystitis. Careful patient selection and preventative measures like pancreatic duct stenting and antibiotic prophylaxis in high risk cases can help reduce the risk of complications.
Interventional radiology has evolved from providing purely diagnostic information to offering minimally invasive therapeutic alternatives to treat abdominal, thoracic, and vascular disorders. Procedures such as biopsies, drainages, angioplasty and stenting can now replace conventional surgery in many cases. Common interventional radiology procedures include liver biopsies, ERCP, PTC, percutaneous nephrostomies, gastrostomies, angioplasty and stenting of vessels. These procedures help diagnose and treat conditions affecting many organ systems such as the liver, bile ducts, kidneys, blood vessels and gastrointestinal tract.
The ureters are tubular structures that transport urine from the kidneys to the bladder. They have multiple layers including epithelium, smooth muscle, and adventitia. Sites of natural narrowing include the ureteropelvic junction (UPJ) and ureterovesical junction. UPJ obstruction is most common in boys and on the left side. It can be caused by intrinsic narrowing at the UPJ or extrinsic compression. Surgical intervention is considered if renal function declines or symptoms develop. Treatment options include open or laparoscopic pyeloplasty, endopyelotomy, or ureterocalycostomy depending on the specifics of each case.
This document summarizes a study evaluating 47 cats with critical urogenital disorders causing abdominal pain. Feline urologic syndrome (FUS) was diagnosed in 18 cats, urinary bladder rupture in 2 cats, polycystic kidney disease in 1 cat, uterine rupture in 1 cat, and closed cervix pyometra in 25 cats. Diagnosis was based on clinical signs, radiography, ultrasonography, bloodwork, and urinalysis. Cats received fluid therapy, antibiotics, and analgesics. Surgical interventions like cystostomy, cystorrhaphy, percutaneous cyst aspiration, and ovariohysterectomy were performed. Most cats recovered well with prompt diagnosis and treatment, though one cat with F
The document discusses guidelines for treating kidney stones. It recommends considering treatment for stones over 15 mm, stones under 15 mm if observation is not preferred, or if the stone has persisted for over 2-3 years. Factors such as patient preference, comorbidities, profession, and ability to travel should also be considered. Treatment options depend on stone size, with percutaneous nephrolithotomy recommended for stones over 2 cm and shock wave lithotripsy or ureteroscopy for smaller stones. The document provides details on the techniques and outcomes of these procedures.
Laparoscopic management of a huge trichobezoar in a teenage girl presenting w...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Liver trauma is an important cause of morbidity and mortality in Pakistan. This study analyzed 113 patients who underwent surgery for liver trauma at a teaching hospital from 2003-2010. Most patients were young males injured in road traffic accidents. Over 80% presented with low blood pressure and over half had other organ injuries as well. The majority had grade I or II liver injuries. The most common surgery was packing the liver with abdominal packing. Post-operative complications occurred in nearly a quarter of patients, with an in-hospital mortality rate of 9.7%. Liver trauma predominantly affects young males and improved emergency response is needed to reduce complications.
This document discusses the diagnosis and management of kidney stones (urolithiasis). It covers the epidemiology, types, diagnosis, and treatment options for kidney stones. For diagnosis, it recommends non-contrast CT scanning as the most sensitive test. For treatment, it describes medical expulsive therapy using drugs to help pass small stones, as well as minimally invasive procedures like ESWL, PNL, and ureteroscopy for larger stones. Factors like stone size, location, and composition are considered when selecting a treatment approach.
Radiological methods such as intravenous urograms (IVUs), ultrasound, CT, MRI, and retrograde/antegrade urography are used to study the urinary system and diagnose diseases. IVUs provide anatomical images of the kidneys and pelvicalyceal systems while ultrasound is useful for differentiating renal cysts from tumors. CT and MRI are valuable for detecting small renal cell carcinomas, urinary tract stones, and other conditions. Emergent conditions like testicular torsion, bladder rupture, renal trauma, and ureteral obstruction can be diagnosed using these radiological techniques.
The application of nanotechnology, microfluidics, bioreactors with kidney cells, and miniaturized sorbent systems to regenerate dialysate makes clinical reality seem closer than ever before. Finally, stem cells hold much promise, But more far realistic. In summary, nephrology is at an exciting crossroad with the application of innovative and novel technologies to RRT that hold considerable promise for the near future. Bioartificial Kidney as an ideal form of RRT would mimic the functions of natural kidneys and be affordable to the patient
This document provides an abstract program for the 25th Annual ACVIM Forum held in Seattle, WA from June 6-9, 2007. It lists 99 oral presentations given over the four days, organized by topic area (e.g. oncology, infectious disease, cardiology, etc.). The presentations include research studies on diseases and conditions in small animals, horses, food animals, and topics related to veterinary internal medicine specialties.
This document describes a case study of a Miniature Dachshund that was diagnosed with a ventricular septal defect (VSD) and aortic regurgitation. Echocardiography revealed a defect between the ventricles and a thickened aortic valve prolapsing into the defect. Cardiac catheterization confirmed a supracristal VSD with aortic regurgitation. Despite medication, the dog's left ventricular dimensions worsened over time. The dog ultimately underwent surgery to close the VSD using cardiopulmonary bypass, which improved the condition and controlled further valve deterioration.
The role of ercp in diseases of the biliary tract and pancreasThorsang Chayovan
This document provides guidelines from the American Society for Gastrointestinal Endoscopy (ASGE) on the role of endoscopic retrograde cholangiopancreatography (ERCP) in diseases of the biliary tract and pancreas. It was developed using an evidence-based methodology including a literature review. The guidelines are intended to apply to all physicians performing GI endoscopy. ERCP is described as useful for diagnosing and treating conditions like gallstones, biliary strictures, pancreatic disease, and leaks or injuries to the biliary tract. Outcomes of ERCP for various conditions are discussed along with appropriate patient selection and techniques.
A presentation about Intravenous Urography (Also known as Intravenous Pyeography).
The presentation contains 41 slides, and is divided into 4 parts :
1 - Introduction.
2 - The procedure.
3 - Examples for abnormal findings.
4 - Studies comparing IVU accuracy with KUB & USG with CT Scan.
This presentation was prepared and presented by me in the tutorials of the Radiology Department of Sebha Medical Center.
Ivu is a radiological investigation for visualization and assessment of the urinary tract.This presentation covers brief anatomy of urinary tract, indication and contraindication,contrast media dose and administration, routine and modified ivu procedure,its complication,ctivu and some abnormalities in the urinary tract.
Litotrissia percutanea laparoscopica nel rene pelvico casi cliniciMerqurio
This document describes a novel technique of laparoscopically assisted percutaneous pyelolithotomy for treating kidney stones in pelvic kidneys. The technique was used in 3 patients with large pelvic kidney stones who were not suitable candidates for standard percutaneous or laparoscopic approaches. The procedure involves using laparoscopy to expose the renal pelvis, then inserting a needle percutaneously into the pelvis under direct visualization. The tract is dilated and a nephroscope is used to remove stones without needing to incise or suture the pelvis. This approach provides direct access to the pelvis without risks of standard percutaneous or laparoscopic techniques. All 3 patients were successfully treated with no complications and no
This study evaluated 59 cats that underwent perineal urethrostomy surgery for feline lower urinary tract disease (FLUTD) at a university veterinary clinic. Early complications within 4 weeks of surgery occurred in 25.4% of cats, most commonly urethral stricture formation. Late complications after at least 4 months included recurring urinary tract infections in 28.2% of cats. Despite frequent complications, 32.2% of cats had no long-term issues, though recurring FLUTD symptoms still occurred in 23% of cats. Overall, the surgery provided a good quality of life for most cats, according to their owners.
UPJ obstruction is most commonly caused by intrinsic stenosis of the proximal ureter. It occurs in approximately 1 in 500 live births, with males and left kidneys more commonly affected. Ultrasound is used to diagnose and monitor hydronephrosis, while diuretic renography can determine if obstruction is present and assess renal function. Surgical correction via pyeloplasty is indicated if renal function is impaired or decreasing, with the Anderson-Hynes dismembered pyeloplasty being the most common procedure performed. Non-operative management with antibiotics may be appropriate if drainage is adequate on functional studies.
- The document presents updated national clinical guidelines for managing palatally ectopic maxillary canines from the Faculty of Dental Surgery at the Royal College of Surgeons of England.
- It describes five treatment strategies supported by levels of evidence: interceptive extraction of the deciduous canine, surgical exposure and orthodontic alignment, surgical removal of the ectopic canine, autotransplantation, and observation with no active treatment.
- The guidelines emphasize the importance of early diagnosis and management of ectopic canines to avoid complex treatment, damage to adjacent teeth, and potential litigation issues from treatment delays.
Long-Term Outcomes of Endoscopic Treatment for Bile Duct Stones in Patients A...JohnJulie1
This study evaluated long-term outcomes of endoscopic treatment for bile duct stones in 211 patients aged 85 years or older. Patients underwent either complete stone removal (group C, n=148) or incomplete stone removal with stent insertion (group I, n=63). Group I had a significantly higher proportion of patients with dementia. Complete stone removal had a longer procedure time but removed significantly smaller stones. Overall survival was significantly higher in group C, but disease-specific survival was similar between groups. The study concluded that endoscopic treatment can be safely performed in elderly patients and advanced age should not preclude complete stone removal.
Long-Term Outcomes of Endoscopic Treatment for Bile Duct Stones in Patients A...JapaneseJournalofGas
This study evaluated long-term outcomes of complete endoscopic stone removal versus incomplete stone removal with stent placement in 211 elderly patients aged 85 years or older with bile duct stones. Patients who underwent complete stone removal had a significantly higher overall survival rate but similar disease-specific survival rate compared to those who underwent incomplete stone removal. The proportion of patients with dementia was higher in the incomplete removal group. Complete stone removal can be safely performed in elderly patients, and advanced age should not preclude attempting full stone clearance.
Endoscopic retrograde cholangiopancreatography (ERCP) is an invasive procedure used to diagnose and treat pancreatic and biliary diseases. While it provides both diagnostic and therapeutic benefits, complications can occur in approximately 5-10% of cases. The most common complication is pancreatitis, occurring in 3-5% of cases, which usually causes abdominal pain and nausea but resolves within a few days. Other potential complications include perforation, bleeding, cholangitis, and cholecystitis. Careful patient selection and preventative measures like pancreatic duct stenting and antibiotic prophylaxis in high risk cases can help reduce the risk of complications.
Interventional radiology has evolved from providing purely diagnostic information to offering minimally invasive therapeutic alternatives to treat abdominal, thoracic, and vascular disorders. Procedures such as biopsies, drainages, angioplasty and stenting can now replace conventional surgery in many cases. Common interventional radiology procedures include liver biopsies, ERCP, PTC, percutaneous nephrostomies, gastrostomies, angioplasty and stenting of vessels. These procedures help diagnose and treat conditions affecting many organ systems such as the liver, bile ducts, kidneys, blood vessels and gastrointestinal tract.
The ureters are tubular structures that transport urine from the kidneys to the bladder. They have multiple layers including epithelium, smooth muscle, and adventitia. Sites of natural narrowing include the ureteropelvic junction (UPJ) and ureterovesical junction. UPJ obstruction is most common in boys and on the left side. It can be caused by intrinsic narrowing at the UPJ or extrinsic compression. Surgical intervention is considered if renal function declines or symptoms develop. Treatment options include open or laparoscopic pyeloplasty, endopyelotomy, or ureterocalycostomy depending on the specifics of each case.
This document summarizes a study evaluating 47 cats with critical urogenital disorders causing abdominal pain. Feline urologic syndrome (FUS) was diagnosed in 18 cats, urinary bladder rupture in 2 cats, polycystic kidney disease in 1 cat, uterine rupture in 1 cat, and closed cervix pyometra in 25 cats. Diagnosis was based on clinical signs, radiography, ultrasonography, bloodwork, and urinalysis. Cats received fluid therapy, antibiotics, and analgesics. Surgical interventions like cystostomy, cystorrhaphy, percutaneous cyst aspiration, and ovariohysterectomy were performed. Most cats recovered well with prompt diagnosis and treatment, though one cat with F
The document discusses guidelines for treating kidney stones. It recommends considering treatment for stones over 15 mm, stones under 15 mm if observation is not preferred, or if the stone has persisted for over 2-3 years. Factors such as patient preference, comorbidities, profession, and ability to travel should also be considered. Treatment options depend on stone size, with percutaneous nephrolithotomy recommended for stones over 2 cm and shock wave lithotripsy or ureteroscopy for smaller stones. The document provides details on the techniques and outcomes of these procedures.
Laparoscopic management of a huge trichobezoar in a teenage girl presenting w...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Liver trauma is an important cause of morbidity and mortality in Pakistan. This study analyzed 113 patients who underwent surgery for liver trauma at a teaching hospital from 2003-2010. Most patients were young males injured in road traffic accidents. Over 80% presented with low blood pressure and over half had other organ injuries as well. The majority had grade I or II liver injuries. The most common surgery was packing the liver with abdominal packing. Post-operative complications occurred in nearly a quarter of patients, with an in-hospital mortality rate of 9.7%. Liver trauma predominantly affects young males and improved emergency response is needed to reduce complications.
This document discusses the diagnosis and management of kidney stones (urolithiasis). It covers the epidemiology, types, diagnosis, and treatment options for kidney stones. For diagnosis, it recommends non-contrast CT scanning as the most sensitive test. For treatment, it describes medical expulsive therapy using drugs to help pass small stones, as well as minimally invasive procedures like ESWL, PNL, and ureteroscopy for larger stones. Factors like stone size, location, and composition are considered when selecting a treatment approach.
Radiological methods such as intravenous urograms (IVUs), ultrasound, CT, MRI, and retrograde/antegrade urography are used to study the urinary system and diagnose diseases. IVUs provide anatomical images of the kidneys and pelvicalyceal systems while ultrasound is useful for differentiating renal cysts from tumors. CT and MRI are valuable for detecting small renal cell carcinomas, urinary tract stones, and other conditions. Emergent conditions like testicular torsion, bladder rupture, renal trauma, and ureteral obstruction can be diagnosed using these radiological techniques.
The application of nanotechnology, microfluidics, bioreactors with kidney cells, and miniaturized sorbent systems to regenerate dialysate makes clinical reality seem closer than ever before. Finally, stem cells hold much promise, But more far realistic. In summary, nephrology is at an exciting crossroad with the application of innovative and novel technologies to RRT that hold considerable promise for the near future. Bioartificial Kidney as an ideal form of RRT would mimic the functions of natural kidneys and be affordable to the patient
This document provides an abstract program for the 25th Annual ACVIM Forum held in Seattle, WA from June 6-9, 2007. It lists 99 oral presentations given over the four days, organized by topic area (e.g. oncology, infectious disease, cardiology, etc.). The presentations include research studies on diseases and conditions in small animals, horses, food animals, and topics related to veterinary internal medicine specialties.
This document describes a case study of a Miniature Dachshund that was diagnosed with a ventricular septal defect (VSD) and aortic regurgitation. Echocardiography revealed a defect between the ventricles and a thickened aortic valve prolapsing into the defect. Cardiac catheterization confirmed a supracristal VSD with aortic regurgitation. Despite medication, the dog's left ventricular dimensions worsened over time. The dog ultimately underwent surgery to close the VSD using cardiopulmonary bypass, which improved the condition and controlled further valve deterioration.
Este documento proporciona información sobre anestesia y analgesia en perros y gatos. Explica los fármacos utilizados para premedicación, inducción anestésica y mantenimiento anestésico, así como analgésicos intraoperatorios. Detalla esquemas de dosis comunes para diferentes tipos de procedimientos y pacientes. Los principales fármacos discutidos incluyen opiáceos, benzodiacepinas, agonistas alfa-2, ketamina e isoflurano.
Guia Practica Analgesia y Anestesia.pdfleroleroero1
El documento presenta cuatro casos de protocolos anestésicos y analgésicos para diferentes procedimientos quirúrgicos en caninos y felinos. Divide los casos en categorías según el grado de dolor esperado y propone opciones de premedicación, inducción, mantenimiento y recuperación para cada uno, destacando la importancia de adaptar los protocolos a cada paciente.
buprenorfina y medetomidina en gatos.pdfleroleroero1
This study investigated the effects of using different combinations of medetomidine and buprenorphine as preanesthetic medications in cats undergoing ovariohysterectomy. Forty cats were divided into four groups receiving different doses of medetomidine alone or in combination with buprenorphine. The results showed that cats receiving 30 μg/kg medetomidine with 20 μg/kg buprenorphine required significantly less isoflurane to maintain anesthesia compared to cats receiving medetomidine alone. Heart rate was significantly lower and oxygen saturation was slightly lower in cats receiving the highest dose of medetomidine and buprenorphine. All groups receiving medetomidine and buprenorphine experienced significantly
This document appears to be a collection of page numbers without any accompanying text. It consists of page numbers from 2 through 11 but provides no other context or information to summarize.
complicaciones en toracotmías en ghatos.pdfleroleroero1
Lateral thoracotomy is commonly used to access the thoracic cavity in dogs and cats for surgical treatment of diseases. This study reviewed 83 cases (70 dogs and 13 cats) that underwent lateral thoracotomy. The most common indication was treatment of a vascular anomaly like a patent ductus arteriosus. Overall survival to discharge was high at 87%, though cats had lower survival than dogs. Younger animals and those undergoing vascular procedures like PDA ligation had higher survival than those undergoing lung or esophageal surgery. Post-operative complications within 2 weeks were reported in 47% of cases, but long-term complications in survivors were rare.
1) The document describes a novel axial pattern flap for nasal and facial reconstruction in dogs. The flap is based on the commissure of the lip and receives blood supply from the angularis oris artery and other arteries.
2) Cadaver studies and dye infusion showed the flap has a reliable blood supply from three direct cutaneous arteries. The flap survived with good results in four clinical cases to reconstruct large facial or nasal defects.
3) The flap provides sufficient skin to reconstruct large defects involving the nose or face. It has a reliable blood supply and versatile design that allows it to be used for various reconstruction needs in dogs.
Laboratorios Richmond División Veterinaria es una empresa argentina dedicada al desarrollo y producción de medicamentos y equipamiento veterinario. Cuenta con instalaciones de investigación, desarrollo y producción que cumplen con los estándares GMP. Exporta sus productos a varios países de América Latina, África y Asia, ofreciendo tratamientos para una variedad de especies animales.
This study evaluated the effect of preoperative intrathecal administration of a low dose of morphine on intraoperative fentanyl requirements in dogs undergoing spinal surgery. Eighteen dogs undergoing cervical or thoracolumbar laminectomy were randomly assigned to receive intrathecal morphine (MG group) or no treatment (CG group). The MG group had significantly lower hourly fentanyl consumption and lower predicted plasma fentanyl concentrations compared to the CG group. This suggests that a low dose of preoperative intrathecal morphine has a sparing effect on intraoperative fentanyl requirements in dogs undergoing spinal surgery. No adverse effects were observed from the intrathecal morphine administration.
This study evaluated the effects of postoperative ketamine administration on pain control and feeding behavior in dogs undergoing mastectomy. Twenty-seven dogs undergoing mastectomy were randomly assigned to receive either placebo, low-dose ketamine, or high-dose ketamine intravenously at the end of surgery and as a 6-hour infusion. Pain levels, opioid requirements, sedation, and food intake were evaluated and compared between groups. The high-dose ketamine group showed significantly improved feeding behavior 20 hours after surgery compared to the low-dose and placebo groups, but opioid requirements did not differ significantly between groups.
This study evaluated the effects of acepromazine (a sedative) on cardiovascular changes induced by dopamine in anesthetized dogs. The researchers found that:
1) Acepromazine prevented the normal return of systemic vascular resistance to baseline levels during higher dopamine doses and reduced the magnitude of arterial pressure increases from dopamine.
2) However, acepromazine did not modify dopamine's ability to increase cardiac index and oxygen delivery, which are beneficial effects.
3) Previous acepromazine administration reduces dopamine's efficacy as a vasopressor agent under isoflurane anesthesia in dogs, but does not alter its other beneficial hemodynamic effects.
recuperación en hipotermia anestesia.pdfleroleroero1
Lower core body temperatures were associated with longer recovery times from general anesthesia in dogs undergoing routine sterilization surgery. Oesophageal temperatures at the end of surgery averaged 36.8°C, with lower temperatures correlated with significantly slower recoveries. Premedication with acepromazine and morphine also significantly increased recovery times compared to dogs that were not premedicated. The choice of induction or maintenance anesthetic agent did not affect recovery time. Hypothermia during general anesthesia can slow recovery through multiple mechanisms, such as decreasing anesthetic requirements and impairing drug metabolism.
This document summarizes a study on the survival characteristics and prognostic variables of dogs with myxomatous mitral valve disease (MMVD), the most common heart disease in dogs. The study included 558 dogs of varying breeds and severity of MMVD. Clinical exams, echocardiograms, and follow-up phone interviews with owners were conducted to evaluate survival times and prognostic factors. Variables found to be associated with reduced survival in univariate analysis included older age, syncope, increased heart rate and dyspnea, higher ISACHC heart failure class, diuretic use, increased end-systolic volume, enlarged left atrium, and higher transmitral flow velocities. Multivariate analysis identified syncope, enlarged left atrium
Este documento presenta información sobre fisiología cardiovascular, respiratoria y del sistema nervioso central. En tres oraciones: 1) Detalla parámetros hemodinámicos como presiones arteriales, índice cardíaco y resistencias vasculares. 2) Explica conceptos como contenido de oxígeno arterial y venoso, transporte de oxígeno y ecuaciones relacionadas a la ventilación. 3) Describe características del flujo sanguíneo cerebral y su regulación, así como parámetros del líquido cefalorraquídeo.
This study evaluated the effects of ephedrine and dopamine on cardiovascular parameters in anesthetized dogs experiencing hypotension. Twelve healthy dogs undergoing orthopedic surgery were randomly assigned to treatment with either ephedrine or dopamine if their mean arterial pressure dropped below 60 mmHg under isoflurane anesthesia. Both drugs improved cardiac output and oxygen delivery, but ephedrine only transiently increased blood pressure while dopamine maintained blood pressure and total peripheral resistance at a higher infusion rate. The study concluded that while both drugs were effective at improving hemodynamics, dopamine provided more sustained blood pressure support.
This document provides guidelines for the recognition, assessment, and treatment of pain in cats and dogs. It discusses the physiology and pathophysiology of pain, as well as methods for assessing acute and chronic pain. Guidelines are provided for managing pain associated with various procedures and conditions through the use of analgesics like opioids, NSAIDs, alpha2 agonists, and local anesthetics. Non-pharmacological approaches like rehabilitation, nutrition, and massage are also addressed. The document aims to help veterinarians effectively recognize and minimize pain in small animal patients.
Este documento describe las bases neuroanatómicas del dolor, incluyendo las vías periféricas y centrales de la transmisión del impulso nociceptivo. También discute el reconocimiento y tratamiento farmacológico del dolor en pequeños animales.
This study compared sevoflurane and isoflurane for maintaining anesthesia in 108 dogs undergoing surgical or diagnostic procedures. Dogs were randomly assigned to receive either sevoflurane (group S) or isoflurane (group I). Both groups had similar heart rates, respiratory rates, blood pressures, temperatures, and times to recovery. However, end-tidal carbon dioxide levels were higher in group S from 30-60 minutes after induction. Sevoflurane required higher vaporizer settings throughout but no adverse events occurred. The study concluded that sevoflurane was a suitable volatile anesthetic for maintaining routine clinical anesthesia in dogs.
El documento describe diferentes técnicas de anestesia general a campo en rumiantes, incluyendo consideraciones sobre la fisiología de los rumiantes y fármacos utilizados. Se enfatiza la importancia del monitoreo anestésico para prevenir complicaciones respiratorias y cardiovasculares comunes en rumiantes en decúbito.
STUDIES IN SUPPORT OF SPECIAL POPULATIONS: GERIATRICS E7shruti jagirdar
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Congestive Heart failure is caused by low cardiac output and high sympathetic discharge. Diuretics reduce preload, ACE inhibitors lower afterload, beta blockers reduce sympathetic activity, and digitalis has inotropic effects. Newer medications target vasodilation and myosin activation to improve heart efficiency while lowering energy requirements. Combination therapy, following an assessment of cardiac function and volume status, is the most effective strategy to heart failure care.
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Giloy in Ayurveda - Classical Categorization and SynonymsPlanet Ayurveda
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The biomechanics of running involves the study of the mechanical principles underlying running movements. It includes the analysis of the running gait cycle, which consists of the stance phase (foot contact to push-off) and the swing phase (foot lift-off to next contact). Key aspects include kinematics (joint angles and movements, stride length and frequency) and kinetics (forces involved in running, including ground reaction and muscle forces). Understanding these factors helps in improving running performance, optimizing technique, and preventing injuries.
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j.1476-4431.2011.00628.x.pdf
1. State-of-the-Art-Review
Ureteral obstructions in dogs and cats: a review
of traditional and new interventional diagnostic
and therapeutic options
Allyson C. Berent, DVM, DACVIM
Abstract
Objective – To describe and review both traditional and newer diagnostic and therapeutic options for canine
and feline ureteral obstructions currently being performed clinically in veterinary medicine.
Data Sources – A Medline search with no date restrictions was used for this review.
Human Data Synthesis – The human literature would support the use of minimally invasive endourological
techniques for the treatment of nearly all causes of ureteral obstructions, whenever possible. This typically
includes extracorporeal shockwave lithotripsy, intracorporeal lithotripsy via retrograde ureteroscopy or ante-
grade percutaneous nephroureterolithotomy, ureteral stenting, percutaneous nephrostomy tube placement,
and laparoscopic endopyelotomy. Typically open surgery is only suggested in cases of ureteral or gyne-
cological malignancy when en bloc resection is considered a good option, or when various methods of
endourological techniques have failed.
Veterinary Data Synthesis – The veterinary literature is scarce on the use of interventional endourological
techniques for the treatment of ureteral obstructions and has been growing over the last 5 years. The current
literature reports the use of extracorporeal shockwave lithotripsy for ureteral stones, as well as the use of ureteral
stents for the treatment of trigonal obstructive transitional cell carcinoma, ureterolithiasis, and ureteral strictures.
Traditional surgical interventions, like ureterotomy, ureteronephrectomy, and ureteral reimplantation is more vastly
reported and accepted. This review will focus on new clinical data using interventional endourological techniques
for ureteral obstructions.
Conclusions – Various treatment options for ureteral obstructions are now available for veterinary patients,
and the trend away from traditional surgical techniques will hopefully be followed now that they are
technically and clinically available for dogs and cats.
(J Vet Emerg Crit Care 2011; 21(2): 86–103) doi: 10.1111/j.1476-4431.2011.00628.x
Keywords: interventional endoscopy, interventional radiology, lithotripsy, nephrostomy tubes, ureteral stents,
ureteral stricture
Introduction
Ureteral obstructions can be difficult to diagnose and
treat in veterinary medicine. The increasing incidence of
ureteral obstructions in veterinary practices, combined
with the invasiveness and morbidity associated with
traditional surgical techniques, makes the use of newer
interventional options appealing. Interventional radio-
logic (IR) and interventional endoscopic (IE) techniques
have enabled clinicians to simultaneously diagnose and
treat ureteral disease in an expedited and minimally in-
vasive manner. The technology involved in these tech-
niques includes the use of fluoroscopy, often with flexible
and rigid endoscopy, for ureteral visualization and to
access various parts of the body. This review will focus
on the application of both IR and IE as tools to diagnose
and manage ureteral obstructions and aid in an algorith-
mic approach to these types of cases. It is important to
understand that most of the data pertaining to IR/IE
treatment of ureteral obstructions are new and still con-
sidered investigational in nature. A large proportion of
this review article is based on the author’s experience,
opinions, and data which have only been published
and presented in abstract form. Traditional therapeutic
options will be reviewed in addition to new alternatives
in dealing with these challenging cases.
The author declares no conflict of interest.
Address correspondence and reprint requests to
Dr. Allyson C. Berent, The Animal Medical Center, 510 E. 62nd St,
New York, NY 10065, USA.
Email: allyson.berent@amcny.org
Submitted August 16, 2010; Accepted January 27, 2011.
From The Animal Medical Center, 510 E. 62nd St, New York, NY 10065.
Journal of Veterinary Emergency and Critical Care 21(2) 2011, pp 86–103
doi:10.1111/j.1476-4431.2011.00628.x
& Veterinary Emergency and Critical Care Society 2011
86
2. Equipment
Various flexible and rigid endoscopes are needed for
the following endourologic ureteral procedures. Rigid
cystoscopy is used for female (dog or cat) ureteral in-
tervention. Ureteral access is possible in a retrograde
fashion in most female patients via IR techniques. Rigid
endoscope diameters range from 1.9 to 7.5 mm. Flexible
ureteroscopes (7.5–8.2-Fr) are used for cystoscopic ac-
cess in male dogs and ureteroscopy in both male and
female dogs, when possible. Different types of intra-
corporeal lithotrites and lasers are available including:
holmium:YAG, diode, ultrasonic, pneumatic, and elec-
trohydraulic. These are typically used for stone disease
or tumor ablation when treating ureteral obstructions.
In addition, extracorporeal shock wave lithotripsy
(ESWL) has great application for ureteroliths in dogs
and sometimes, but less commonly, cats.1–3
A traditional fluoroscopic C-arm is sufficient for visu-
alization and ureteral intervention. A mobile C-arm has
the ability to move the image intensifier and gain various
tangential views of the renal pelvis and ureter. Ultra-
sonography is useful for percutaneous renal access in
order to cannulate the ureter in an antegrade manner, or
for the placement of a nephrostomy tube. This can also be
done under direct fluoroscopic guidance when the renal
pelvis is already opacified with contrast. Various guide-
wires and catheters are also needed for each procedure,
and a discussion of these can be found elsewhere.4
Uret-
eral stents, which are available in numerous dimensions,
are soft polyurethane-type catheters that have a double
pigtail multifenestrated design. They can be easily re-
moved after resolution of ureteral disease if necessary,
but are often considered long-term treatment options.
Additional interventional techniques that will be dis-
cussed for the management of ureteral disease include
the placement of nephrostomy tubes and the use of a
subcutaneous ureteral bypass (SUB).
Etiology
Ureterolithiasis is the most common cause of ureteral ob-
structions in both dogs and cats,5,6
though trigonal ne-
oplasia,a,7
ureteral strictures (congenital or acquired),b
dried solidified blood clots/calculi8
or other tumor types
have also been reported.9
Greater than 98% of feline, and
over 50% of canine ureteroliths were recently docu-
mented to be composed of calcium oxalate.5,6,10–12
These
types of stones do not dissolve medically and either need
to pass spontaneously, be removed, or managed, to per-
mit urine passage. Once medical management fails (tra-
ditionally this involves, eg, IV fluid therapy, mannitol
continuous rate infusions [CRI], and a-adrenergic block-
ade, amitriptyline, glucagon), partial obstructions were
traditionally tolerated and often left untreated (benign
neglect) due to the risk:benefit ratio of attempted surgical
removal. If there is a complete ureteral obstruction, de-
compression of the renal pelvis was typically encouraged.
This approach to management has more recently changed
in the author’s practice and immediate treatment of par-
tial ureteral obstructions is typically recommended.
The physiologic response to a ureteral obstruction is
very complex both before and following its relief. Fol-
lowing a ureteral obstruction studies in normal dogs have
demonstrated that ureteral pressures increase immedi-
ately and can take over 24 hours after obstruction relief
for the pressure to decrease.13
After this increase in pres-
sure renal blood flow diminishes to 40% of normal over
the first 24 hours and drops to 20% of normal by 2
weeks.14,15
The excessive pressure is transmitted to the
entire nephron and a decrease in glomerular filtration
rate (GFR) occurs via concurrent vasoactive mediator re-
lease, leukocyte influx, and subsequent fibrosis.14
The
contralateral kidney will have an increase in the GFR in
response. The longer the ureter remains obstructed, the
more damage occurs, which may be irreversible depend-
ing on severity and duration of the obstruction. In a study
of normal dogs, it was found that after 7 days of ob-
struction the GFR was permanently diminished by 35%,
and when the obstruction lasted for 14 days the GFR was
diminished by 54%.13–18
These numbers were obtained in
a canine model with complete obstruction, without pre-
existing azotemia, chronic interstitial nephritis, or chronic
obstructions, so extrapolation of a worse outcome might
be expected in dogs and cats that are obstructed, making
aggressive and timely intervention imperative. It was also
documented in these studies that it took over 4 months to
get the maximal return to function.16–18
Interestingly, in
contrast to the irreversibility of a complete obstruction,
partial obstructions resulted in less severe destruction
with greater return of function after the obstruction is
relieved. In 1 dog model it was found that the GFR re-
turned to normal after a partial obstruction was present
for 4 weeks.13
Knowing that many patients are partially
obstructed with concurrent renal compromise, eg, chronic
renal disease (CKD), aggressive management and reso-
lution is recommended to improve overall outcome.
The normal diameter of the canine ureter based on
computed tomography (CT) measurements ranges from
1.3 to 2.7mm (3.9–8.1-Fr).19
The normal internal diam-
eter of the feline ureter is approximately 0.4 mm (1.2-Fr),
whereas the outside diameter reaches 1 mm (3-Fr).20–24
The ureter sits in the retroperitoneal space connecting
the renal pelvis to the urinary bladder. It is lined with
transitional cell epithelium and composed of several
layers of smooth muscle surrounding the mucosal layer,
allowing the peristalsis of the ureter and urine propul-
sion from the kidney to the urinary bladder.20,21
In the
dog and cat the ureteropelvic junction is covered by re-
nal parenchyma. Once the ureter exits the kidney it
& Veterinary Emergency and Critical Care Society 2011, doi: 10.1111/j.1476-4431.2011.00628.x 87
Image-guided interventions in ureteral obstructions
3. passes dorsally. The right ureter typically passes lateral
to the caudal vena cava, whereas the left ureter is usually
lateral to the aorta. In the case where the ureter is seen to
pass dorsal to the caudal vena cava, this is termed a
circumcaval (or retrocaval) ureter. In a normal cat, as the
ureter passes caudally, it passes ventrally, enters the lat-
eral ligament of the bladder and then the distal end
curves resulting in a ‘J-shaped’ hook, entering the dorsal
aspect of the bladder neck at the ureterovesicular junc-
tion (UVJ).22
In cats the UVJ is typically found in the
proximal urethra at the junction of the trigone.
Ureteral interventions in people
In human urology the development and improvements in
ureteroscopy, ureteral stenting, ESWL, laser lithotripsy,
laparoscopy, and percutaneous nephroureterolithotomy
(PCNUL) have almost eradicated the need for open uret-
eral surgery for stone disease, strictures, trauma, neoplasia,
and congenital anomalies.25–35
Currently, ureteroscopy is
the first line modality for the evaluation and treatment of
ureteral neoplasia, upper tract essential hematuria, ureteral
calculi 45mm, and evaluation for ureteral obstructions.
Ureteroliths o5mm have a 98% chance of spontaneous
passage with medical management alone (eg, a-blockade).
For larger stones, or those that do not pass spontaneously,
ESWL is effective in 50–81% of cases, though most of
the literature suggests this number is closer to 50–
67%.25–27,33,35
Ureteroscopy has a near 100% success rate
when a holmium:YAG laser lithotripsy is used.25,26,34
PCNUL has been successful for large proximal impacted
ureteral stones.7
Ureteral stenting was first introduced in
1967 for management of people with malignant ureteral
obstructions.30
They are still widely used to treat both be-
nign and malignant obstructive disease and this is consid-
ered standard-of-care in many instances. There has been
documented success in stent placement for distal malig-
nant obstructions of 496% when placed in an antegrade
manner when nephrostomy access is obtained through the
kidney, versus only 50% when placed in a retrograde
manner.30
Ureteral stenting for stone disease is typically
done after ureteroscopy for the management of postscop-
ing spasm and edema, and in children it has been per-
formed before ureteroscopy to allow for passive ureteral
dilation, immediate ureteral bypass, future ureteroscopy,
and spontaneous stone passage.33
With this understanding
a similar approach is starting to be used in veterinary
medicine over the past 5 years in a few veterinary facilities.
History and clinical presentation
Feline patients with ureteral obstruction(s) typically pres-
ent with vague signs associated with vomiting, lethargy,
a decreased appetite, and acute or chronic weight loss.5
If
the patient is severely azotemic then signs of uremia may
be present such as polyuria, polydipsia, vomiting, ano-
rexia, oral ulcerations, weakness. Unless there are con-
current bladder or urethral stones, or a trigonal mass,
signs of dysuria are not commonly observed. Concurrent
urinary tract infections are not as common in cats (ap-
prox 33%)4
as in dogs (77%),12
and ureteral colic can be
associated with signs of dysuria or stranguria, but this
appears to be less common in cats than dogs. Pain on
palpation of the affected kidney is more commonly seen
in acute obstructions.
Clinical presentation in dogs with a ureteral obstruc-
tion is typically associated with dysuria (incontinence,
stranguria, hematuria, polyuria, pollakiuria) and signs of
systemic illness (eg, vomiting, inappetance, depression,
lethargy). Most dogs (77%) with a ureteral obstruction
have associated pyelonephritis and cystitis. This is per-
haps why more dogs have generalized signs of systemic
illness.12
Dramatic signs of lower urinary tract disease are
more commonly associated with ureteral colic, cystitis,
or concurrent lower urinary tract disease (eg, trigonal
tumor, urethral or bladder stones, polyps, masses).
Diagnosis
On physical examination it is common to palpate 1 en-
larged kidney and 1 small kidney in cats. In dogs renal
pain is more common and is typically associated with
the concurrent pyelonephritis and capsular inflamma-
tion. Pallor and associated anemia is common in cats,
and evidence of a heart murmur is often auscultated.
Biochemical parameters: Cats are often anemic (48%)
at diagnosis and this is either due to concurrent CKD or
from excessive blood sampling during previous hospi-
talizations.5
Dogs often have a moderate to severe neu-
trophilia associated with concurrent pyelonephritis and
44% of dogs with ureterolithiasis-induced obstructions
were reported to have some degree of thrombocytopenia,
which can be quite severe (o40,000 platelets). The
thrombocytopenia may be secondary to sepsis or a
secondary immune-mediated thrombocytopenia.12
Azo-
temia is common at the time of diagnosis (83% of cats and
50% of dogs were azotemic with a unilateral obstruc-
tion).5,6,12
The degree of azotemia does not appear to be
associated with outcome if early decompression is un-
dertaken. Hyperphosphatemia was documented in 54%,
hyperkalemia in 35%, hypercalcemia in 14%, and hypo-
calcemia in 22% of cats with ureteral obstructions.5,6
On
urinalysis crystals were observed in the urine of 29% of
cats (amorphous crystals and calcium oxalate being most
common). Urinary tract infections were documented in
8% of cats in 1 study6
and over 30% of cats in another
study,c
whereas 77% of dogs were documented to have
positive stone or urine bacterial cultures.12
Imaging: Bilateral ureteral obstructions were docu-
mented in 19% of cats5,6
and 12.5% of dogs.12
& Veterinary Emergency and Critical Care Society 2011, doi: 10.1111/j.1476-4431.2011.00628.x
88
A.C. Berent
4. Radiopaque calculi (Figure 1) are typically visible in
patients with calculi-induced obstructions. In some pa-
tients an enema is necessary in order to better visualize
the entire ureter and associated renal pelvis. The com-
bination of radiographs and ultrasound is preferred in
the diagnosis of ureteral obstructions. The benefit of the
radiographs is to document stone size, number, loca-
tion, and the presence of concurrent nephrolithiasis.
These are often underestimated with ultrasound.
Ultrasound is ideal for the documentation of hydro-
ureter, hydronephrosis, and the exact location of the
obstructive lesion. If a trigonal tumor is presently caus-
ing the ureteral obstruction then a hydroureter would
be expected to extend to the level of the UVJ. If hydro-
ureter is present and very proximal, with no evidence
of a shadowing stone at the junction of normal and
abnormal ureter, then one might expect a ureteral stric-
ture to be present. In a recent study 60% of cats with a
ureteral stricture had evidence of peri-ureteral hyper-
echoic tissue at the stricture site on ultrasound.b
Iden-
tifying concurrent nephroliths and other ureteroliths is
vital in therapeutic decision making when considering
traditional surgery, ureteral stenting, or ESWL. One
study documented 62% of cats had concurrent neph-
roliths and 9% cystic calculi, whereas 50% of canine
patients had concurrent nephroliths.5,6,12
Another key
piece of information is knowing the exact diameter of
the dilated renal pelvis based on the ultrasound. It is
important to know which interventional option is best
for each patient and ensure that the loop of a locking-
loop pigtail nephrostomy tube or ureteral stent fits
inside the renal pelvis if that modality is being consid-
ered. The sensitivity for abdominal radiographs for fe-
line ureteral calculi was 81% (versus 88% in dogs) and
for abdominal ultrasound was 77% (versus 100% in
dogs).12
In combination the sensitivity of both radiog-
raphy and ultrasound was 90% in cats.5,6
Percutaneous antegrade pyelography: Percutaneous
antegrade pyelography provides good visualization of
the renal pelvis and ureter, and allows localization of
the ureteral obstruction and aids in determining
whether a complete or partial obstruction is present.36
In brief, the animal is anesthetized, or heavily sedated,
and the area over the kidney is clipped and aseptically
prepared. Using ultrasound guidance and a 22-G IV
catheter the renal pelvis is approached through the
greater curvature of the kidney. The needle is attached
to a 3-way stopcock and extension set. Once inside the
renal pelvis, urine is collected for bacterial culture and
urinalysis and iohexola
is injected (comprising 50% of
the urine volume that was removed). Images should be
obtained immediately and again at 5 and 15 minutes.
Ideally, this procedure should be performed under
fluoroscopic guidance, which allows visualization of
the filling of the ureter and the point of obstruction in
real time. In a study of 11 cats the sensitivity and spec-
ificity was excellent in the cases where the study could
be interpreted.36
Forty-four percent of the studies had
evidence of leakage and 30% was not diagnostic, mak-
ing its use somewhat more limited.36
With the im-
provement in ultrasound imaging, the confidence of
obstruction based on ultrasound and radiographs, the
more aggressive treatment of partial obstructions, as
well as the need for pyelography during treatment
(ureteral stenting, nephrostomy tube placement, or SUB
placement), the use of purely diagnostic antegrade
pyelography has declined tremendously in the author’s
practice, and is instead performed intraoperatively
during obstruction relief (Figure 1).
Retrograde ureteropyelography is performed via cystos-
copy and fluoroscopy by cannulating the UVJ and in-
jecting contrast.d
This procedure allows for irrigation of
contrast in a retrograde manner in order to document
ureteral patency, space occupying lesions, stone dis-
ease, tortuosity of the ureter, and the ureteral diameter.
This is seemingly more accurate than IV pyelography
(IVP), allowing for ureteral distension and higher con-
trast concentrations during ureteral irrigation without
the dilutional effect observed with an IVP and the po-
tential risk of contrast-induced nephropathy. The con-
trast agent remains in the renal collection system and is
not injected intravascularly, having no ill effect on the
nephrons. This procedure is also less invasive than an-
tegrade pyelography, eliminating the need for needle
access and the risk of subsequent bleeding or urinary
leakage through the renal parenchyma if a ureteral ob-
structive lesion persists (Figure 1).
CT: Computed tomography can be performed pre-
operatively when traditional surgical options are
anticipated if the stone number and location is not
clear based on radiographs and ultrasound. IV contrast
administered during the CT scan can aid in concurrent
differentiation of partial or complete obstructions. IVP
is often not useful in animals with ureteral obstructions
due to the poor filling of an obstructed kidney and the
nephrotoxicity risk of the contrast material that is being
filtered by the kidneys during the nephrogram phase,
particularly considering a significant number of both
dogs and cats are azotemic at the time of diagnosis. The
risk is theoretical at this point but should be considered.
In certain instances an IVP might be indicated. With the
advent of ureteral stenting, the location of the stones is
slightly less important if the entire ureter will be by-
passed by a stent, and most of the stones will not ul-
timately be removed. This is not the case when
traditional surgical therapy is being performed.
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5. GFR studies/scintigraphy: The GFR of individual
kidneys can be measured by technetium Tc 99 dieth-
ylenetriamine pentacetic acid scintigraphy. The GFR of
an obstructed kidney is most often reduced, and the
predictability of return to function based on scinti-
graphy is often unclear, potentially significantly under-
estimating postrelief renal function. The measurement
of the GFR of the contralateral kidney may assist in the
decision whether to treat unilateral or bilateral obstruc-
tions, or potentially perform a nephrectomy if abso-
lutely necessary (not typically recommended).22
Treatment
There is a paucity of information reported in the literature
on the treatment of canine or feline ureteral obstructions
aside from a large surgical case series in cats (153 cases)6
and 1 small surgical case series in dogs (16 cases).12
Other
reports are often based on anecdotal experience or a sub-
set of patients from this larger case series.
Medical management: Medical management should
be initiated immediately following diagnosis of a uret-
eral obstruction, as stabilization is often required and a
majority of cats will present with concurrent kidney
disease and azotemia. Medical management alone has
been shown to be effective in a minority of cats with
stone disease in 1 study,5
and there are no reports in
dogs. Only 17% of patients were reported to have
movement of their ureteral stones to either complete or
partial passage with aggressive medical management.6
It is important to remember that movement to a partial
obstruction is not considered resolution of the condi-
tion, and progressive renal damage will likely still en-
sue, albeit at a slower rate. Because there is a small
chance of complete stone passage (typically under
10%), medical management should always be consid-
ered before any more invasive intervention.6
Dogs may
not always present azotemic, but because over 75% of
dogs with a ureteral obstruction had concurrent urinary
tract infections broad spectrum antimicrobial therapy is
indicated.12
It is very important that if medical man-
agement is not successful in relieving the obstruction
within 48–72 hours, as documented via serial radio-
graphs, blood work, and ultrasound examinations,
more aggressive interventions should be considered
in order to avoid excessive loss of renal function.
Medical management should consist of aggressive IV
fluid therapy, being careful to monitor central venous
pressures, body weight, electrolyte concentrations, and
hydration status. It is not uncommon for patients, par-
ticularly cats, to become fluid overloaded both before
and after any ureteral intervention. This is typically
seen preoperatively during a diuresis period or post-
operatively during high IV fluid therapy rates. Care
should be taken to prevent excessive fluid volumes and
monitor hydration status very carefully. The fluid ther-
apy protocol typically recommended by the author
includes administering a maintenance rate of fluids (eg,
Figure 1: Imaging in animals with ureteral obstructions. (A) Lat-
eral abdominal radiograph showing multiple stones (white arrow)
in the ureter of a cat. (B) Ultrasound image of a canine proximal
ureter and renal pelvis showing multiple stones in the proximal
ureter just past the ureteropelvic junction (UPJ). (C) Aventrodorsal
radiograph in a feline patient after a percutaneous antegrade
pyelogram with a proximal ureteral obstruction (stricture-black
arrow). (D) A ventrodorsal projection during a retrograde ureter-
opyelogram using fluoroscopic and cystoscopic guidance in a cat.
White arrow is the open-ended ureteral catheter.
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6. 50–60 mL/kg/d) using 0.45% saline mixed with 2.5%
dextrose and then a replacement fluid (typically avoid-
ing saline if possible due to sodium load) to correct
hydration status and promote diuresis (eg, 45–75 mL/
kg/d). Again, careful monitoring of fluid therapy is
very important. In addition to IV fluid therapy the use
of an osmotic diuretic is often recommended. For pa-
tients that do not have any cardiac compromise, a CRI
of mannitol is typically chosen by the author. The
author starts with a bolus at 0.25–0.5 g/kg over 20–30
minutes followed by a CRI at 1 mg/kg/min for 24
hours. If after 24 hours there is no evidence of im-
provement based on imaging this is discontinued.
Other medical considerations include amitriptyline,37
a-adrenergic blockade (prazosin or tamsulosin),38
or
glucagon therapy.e
In cats only anecdotal evidence ex-
ists regarding the medical management strategies dis-
cussed. One study evaluated the response of normal
canine ureters and compared various spasmolytics.38
In
people, a-1 adrenergic antagonists, eg, tamsulosin (a-
1a/1d adrenergic antagonist), was the treatment of
choice for the expulsion of small ureteral stones. It is a
very potent spasmolytic and is very effective in reliev-
ing a ureteral obstruction when stones are distal and
o5 mm in diameter.39
A study in dogs comparing var-
ious antispasmotics including a-adrenergic antagonists
(tamsulosin, prazosin [a-1 non-selective–adrenergic an-
tagonist], an experimental b-2/b-3 adrenergic agonist,
verapamil [a calcium channel blocker], and papaverine
[a phosphodiesterase inhibitor]), showed that the b-
adrenergic agonist had the most efficacious ureteral
relaxant abilities, and tamsulosin was the second most
effective.39
Prazosin had little effect, and was actually
shown that in high concentrations it enhanced sponta-
neous contractions.38
This suggests that further inves-
tigation into the use of a b-adrenergic agonist or
tamsulosin in dogs and cats with ureteral obstructions
is warranted. Amitriptyline is a potent urinary smooth
muscle relaxer mediated by the opening of voltage-
gated potassium channels. One study evaluating
amitriptyline in cats with urethral obstructions demon-
strated that amitriptyline was effective in relieving ure-
thral obstructions and relaxing the muscle of normal
human and porcine ureteral segments.37
This has since
been extrapolated for use in canine and feline ureteral
obstructions. The recommended dose is 1 mg/kg, PO,
per day but no documented clinical evidence has been
reported for its use in veterinary ureteral disease.37
Glucagon is another medical option which theoretically
causes relaxation of the ureteral smooth muscle, pro-
moting passage of ureteral calculi. An abstract evalu-
ating the use of glucagon for ureteral obstructions in 25
catse
demonstrated that glucagon improved urine out-
put in previously oliguric cats but there was no doc-
umented short- or long-term benefit for the ureteral
obstruction.e
Major side effects associated with glu-
cagon include vomiting, diarrhea, dyspnea, and tachy-
pnea. The dose of glucagon reportedly used is 0.1 mg/
cat, IV, every 12 hours for up to 4 doses; however, many
clinicians would recommend against its use, or recom-
mend its use with caution. Another study evaluated
glucagon and ritodrine in a canine model of ureteral
obstruction.40
This study demonstrated a reduction in
intraluminal pressure of the ureter and a reduction in
the peristalsis rate, but the effect was not particularly
prolonged, and was considered clinically irrelevant.40
When medical management fails or the patient is un-
stable (eg, hyperkalemic, excessively overhydrated, or
becoming oliguric) then immediate intervention should
be considered. If immediate resolution (via ureterotomy,
ureteral reimplantation, ureteral stenting, or SUB) is not
possible then the 2 best options are either to place a
nephrostomy tubef
or initiate intermittent hemodialysis
or continuous renal replacement therapy (CRRT). The
author typically recommends immediate renal pelvis
decompression over hemodialysis or CRRT if the patient is
stable to undergo anesthesia and the operator is comfort-
able placing the draining tube. By relieving the obstruc-
tion several goals are accomplished: (1) improvement of
azotemia and electrolyte status, (2) prevention of further
nephron damage from the increased hydrostatic pressure,
(3) alleviation of the ureteral colic caused by the obstruc-
tion, (4) enabling the potential for retrograde migration of
the obstructing stone after ureteral decompression, and
(5) allowing time for a postobstructive diuresis to occur
through the nephrostomy catheter (which is a larger di-
ameter) rather than a smaller diameter ureteral stent or
edematous ureteral surgical site.
Nephrostomy tube placement: A nephrostomy tube
(Figure 2) will rapidly and effectively relieve a ureteral
obstruction, as well as enable the determination of
whether adequate renal function remains before sub-
jecting a patient to a prolonged anesthesia for definitive
ureteral surgery. The catheter recommended for this
procedure is a locking-loop pigtail catheter.g
A study
using a dog model for ureteral obstruction demon-
strated that after a nephrostomy tube was placed 75%
of the dogs passed an implanted artificial steel ball,
which was the stone model, into the urinary bladder.41
A smooth metal ball should pass much easier than an
irregular calculus, but these data may suggest that by
relieving the increased ureteral and renal pelvic pres-
sure the excessive ureteral spasm and edema created by
the stone may be relieved and encourage stone passage.
This is speculative, but possible. In a recent series of 19
dogs and cats, locking-loop nephrostomy tube place-
ment was reported.f
No leakage occurred in any of
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7. these patients, but 1 dog accidentally removed the tube
at home while running out of the crate 5 days after
placement.f
This dog did not have a nephropexy as his
tube was placed percutaneously, and no ill effects were
noted from this incident.f
It is recommended that nephrostomy tubes should be
placed percutaneously in dogs and surgically in cats
due to the mobility of the feline kidney and greater risk
for leakage without a surgical nephropexy. The loop on
the catheter is approximately 10 mm in diameter so this
procedure is reserved for dogs and cats that have a
renal pelvis 410 mm. If the entire loop is not securely
situated inside the renal pelvis then leakage can occur.
The author typically use a 6-Fr catheterg
in dogs and a
5-Fr catheterh
in cats. Percutaneously, this procedure is
performed with ultrasound, fluoroscopic guidance, or
Figure 2: Nephrosotmy tube placement. Seldinger-technique displaying the placement of a locking-loop pigtail catheter over a
guidewire inside the renal pelvis of a feline patient. (A) A pigtail catheter over a guidewire showing it is straight to start. (B) Once the
wire is removed the loop starts to form. (C) Once the string is locked in the loop tightens. (D) Representing the catheter over the
guidewire inside the renal pelvis after a pyelogram is performed. (E) The loop of the pigtail is advanced over the wire as depicted in
(B). (F) The lock is formed inside the renal pelvis, as depicted in (C). (G) One-stab technique showing the sharp trocar inside the
stylette of the locking-loop pigtail catheter. (H) A percutaneous pyelogram in a cat with a proximal ureteral stricture. (I) A locking-
loop pigtail catheter being advanced into the renal pelvis with the sharp trocar (white arrow) through the greater curvature of the
kidney. (J) The locking-loop pigtail catheter in place and locked inside the renal pelvis.
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8. both. With ultrasound alone a ‘one-stab’ technique can
be performed. A stab incision is made through the skin
in the location of puncture. The locking-loop pigtail
catheter is straightened by the hollow stylette. Then the
sharp trocar is placed within the hollow stylette (which
come together as a set). This sharp trocar is used to
puncture the greater curvature of the kidney with care-
ful ultrasound guidance. Large vessels should be
avoided with color-flow Doppler when possible. Once
the catheter is seen inside the renal pelvis the sharp
trocar is removed. Now the hollow stylette is carefully
withdrawn from the catheter as the pigtail catheter is
advanced into the renal pelvis. Once the catheter is seen
to start forming a curl the locking string is gently pulled
tight to encourage the pigtail to form and lock inside
the renal pelvis. Once the catheter is in place urine
should be removed from the catheter and emptying of
the renal pelvis should be documented on ultrasound.
At this time a pyelogram can be performed to confirm
that no leakage has occurred. The catheter is securely
sutured to the skin by purse-string suture followed by
finger trap suture pattern. The tube should be tacked to
the skin in 3–4 separate locations using surgical tape or
serial finger traps to secure the tube from any possible
traction to the kidney. The tube should then be wrapped
and secured carefully around the abdomen. This should
remain in place for 2–4 weeks for tract formation, or
the hole can be closed surgically if a laparotomy for
definitive resolution is subsequently performed. If the
tube is placed surgically, which is recommended in cats,
a surgical nephropexy is concurrently performed and the
tube can be removed as soon as the ureteral obstruction is
permanently relieved.
The ‘Seldinger-technique’ for nephrostomy tube
placement requires both ultrasound and fluoroscopic
guidance. For this procedure a pyelocentesis and uretero-
pyelogram is performed using a renal access needlei
un-
der ultrasound guidance. Under fluoroscopic guidance,
an angled guidewirej
is passed through the needle and
coiled into the dilated renal pelvis. The locking-loop pig-
tail catheter is then straightened out with the hollow tro-
car. The renal access needle is removed, and the
nephrostomy tube set is advanced over the guidewire
into the renal pelvis. Once the catheter is observed via
fluoroscopy to be inside the renal pelvis, the catheter is
advanced off the hollow stiff stylette and the curl is
formed over the wire inside the renal pelvis. Once the
curl is in the renal pelvis entirely the pigtail is locked
and the catheter and hollow stylette are removed. The
catheter is secured to the body wall as described above.
The tube should be tested with a pyelogram to ensure
that no leakage is present or that there is no resistance to
drainage. The entire system is then attached to a closed
gravity drainage collection system. This allows for exter-
nal renal drainage, elimination of excessive hydrostatic
pressure, and patient stabilization before a more perma-
nent fixation (eg, ureterotomy, ureteral reimplantation,
ureteral stent placement, ureteral bypass). During ne-
phrostomy tube placement the guidewire maybe be able
to be advanced down the entire ureter around the ob-
struction. If it bypasses the obstruction, and through and
through access is obtained, a ureteral stent can be placed
as detailed later in this review.
Dialysis: Dialysis, including initiate intermittent
hemodialysis and CRRT, may be useful to stabilize pa-
tients with ureteral obstruction. In particular, patients
with severe hyperkalemia or life-threatening volume
overload (ie, pulmonary edema) may benefit from these
types of treatment. Dialysis can make the patient more
stable for anesthesia for a definitive procedure (eg, ure-
terotomy or ureteral stent placement). While placing a
dual lumen catheter for dialysis may require sedation, it
is generally a quick procedure with less morbidity than
surgery or percutaneous nephrostomy tube placement.
The optimal treatment protocol will depend on the spe-
cifics of the case. Because many of these patients suffer
from volume overload and marginal hypotension, slow
gradual removal of the fluid over several hours (eg,
6–24 h) may be desirable. If definitive care is not im-
mediately available, dialysis can be performed daily or
continuously until the procedure can be scheduled.42
Surgical management: Traditional intervention has
been accomplished surgically via ureterotomy, ureteral
reimplantation, ureteronephrectomy, and at times renal
transplantation. Kyles et al5,6
reported 2 retrospective
studies involving over 150 cats.5,6
There were various
procedure-associated complications (over 30%) and the
mortality rates ranged from 18% to over 30%, depend-
ing on the type of procedure performed or management
necessary (eg, concurrent nephrostomy tubes or hemo-
dialysis).5,6
These studies not only included cats that
had a ureterotomy or ureteral reimplantation, but also
those that had renal transplantation or ureteronephrec-
tomy procedures. Considering most cats with a ureteral
obstruction are not considered candidates for uretero-
nephrectomy (with the majority [480%] being azote-
mic), and a renal transplantation should be reserved for
patients with irreversible renal azotemia, not necessar-
ily postrenal azotemia, the outcome for the type of pa-
tients we see clinically is likely different than the larger
series reported previously.5,6
The studies published by
Kyle and colleagues were collaborations from 2 uni-
versities with extensive experience in ureteral surgery
when compared with most surgical practices or insti-
tutions, as active renal transplantation programs ex-
isted and microsurgical expertise was available at that
time. The morbidity and mortality may be higher in
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9. environments where operating microscopes and micro-
surgical expertise is not as readily available. These were
also cases that were considered ‘surgical candidates,’
where more recently the large number of stones com-
monly seen in a feline ureter and renal pelvisc
make
surgical intervention alone challenging, if not some-
times impossible (Figure 1).
Depending on the site of obstruction, the number of
stones obstructing, and the reason for the obstruction, the
type of surgery considered may vary. A ureteronephrec-
tomy would be the least complicated procedure with the
least number of procedure-associated complications
when compared with other ureteral surgical options. Pa-
tients who are nonazotemic and have a normal GFR to
the contralateral kidney would be the only candidates for
this procedure. Knowing that over 30% of older cats will
develop chronic kidney disease43,44
with time, and many
cats will eventually develop a stone in the contralateral
kidney/ureter, removing 1 of the kidneys rather than
treating the underlying ureteral disease is less than ideal
and cannot not be recommended. There is also evidence
from the limited literature that over 50% of cats and
nearly 40% of dogs will remain azotemic after treatment
of a ureteral obstruction, further supporting the need to
preserve all renal function when possible and avoiding
ureteronephrectomy.c,6,12
A ureterotomy or ureteral reimplantation are the 2 most
commonly performed traditional surgical techniques for
the treatment of ureteral obstructions in dogs and cats. It
is very important to be sure that all stones are removed
during this surgery as stones o1mm in diameter may be
difficult to palpate digitally at the time of surgery and can
result in surgical site obstruction. Finally, if the obstruction
is very proximal then a nephrocystopexy and ureteral re-
implantation or renal descensus and psoas cystopexy may
be considered.22
Many of the associated complications with surgery are
due to site edema, recurrence of a ureteral obstruction
from stones that pass from the renal pelvis to the surgery
site, stricture formation, and ureterotomy-associated or
nephrostomy tube-associated urine leakage.b,5,6
In the
study by Kyles et al5
over 10% of cats that survived the
these surgical complications required a second surgical
procedure during the same visit and 30% were subse-
quently euthanized or died for serial complications.6
Of
the large number of cats in that study, a relatively small
number had long-term imaging follow-up, and 40% of
those that were followed had evidence of a recurrence of a
ureteral obstruction, from either further stone formation
or passage of a previous nephrolith. Eighty-five percent of
the cats that had stone recurrence had evidence of
nephrolithiasis at the time of the first ureteral surgery.6
The number of animals that did not have stone recurrence
with prior nephrolithiasis was not evident in that study. In
spite of all of the surgical concerns, the survival rates were
dramatically higher for cats that had intervention per-
formed when compared with those treated with medical
management alone.
Finding a less invasive alternative that results in im-
mediate decompression and stabilization of associated
azotemia, addresses all stones in both the kidney and
ureter to prevent future obstructions, preventing reob-
struction, stricture or leakage, and concurrently allows
patency to be established would be ideal. In people, min-
imally invasive treatments have largely replaced open
surgery.25–35,45,46
The placement of a double pigtail ureteral
stent, either minimally invasively (IR technique) or surgi-
cally assisted, could potentially circumvent the complica-
tions of surgery alone (eg, leakage, stricture, reobstruction),
prevent nephroliths from causing future obstructions, and
quickly and efficiently stabilize the patient while decreas-
ing renal pelvic pressure and stopping the cycle of pres-
sure-induced nephron death and renal fibrosis.
Interventional management: As already described,
nephrostomy tube placement is considered an interven-
tional procedure, requiring fluoroscopy, ultrasound, or
both. Ureteral stenting (Figures 3–5) has been performed
for a variety of disorders in both dogs and cats.a,b,c
This
procedure has been performed successfully in over 150
cases in the author’s practice to date. The goals of uret-
eral stenting are 5-fold: (1) to divert urine from the renal
pelvis into the urinary bladder to bypass a ureteral
obstruction, (2) to encourage passive ureteral dilation
(for ureteral stenosis/strictures, multiple ureteral stones,
prevent reobstruction, encourage stone passage, or future
ureteroscopy), (3) to decrease surgical tension on the
ureter after/during surgery (especially resection and
anastomosis) and prevent postoperative leakage and
edema, (4) to aid in extracorporeal shockwave lithotripsy
for large obstructive ureteroliths or nephroliths that
could result in serial ureteral obstructions if the stones
do not completely pass down the ureter passively, a term
called Steinstrasse,45
and (5) to prevent the migration of
nephroliths resulting in future ureteral obstruction. The
main type of ureteral stent used in veterinary medicine is
an indwelling double pigtail ureteral stentk
(Figure 3).
The double pigtail stent is completely intracorporeal and
can remain in place for numerous months-years if nec-
essary (recommended for o3–6 mo in people but has
been left in place for over 4 y in dogs and cats). In many
circumstances in the author’s practice this is currently
considered a long-term treatment option for various
causes of ureteral obstructions in both dogs and cats.a,b,c,7
It is important to realize that ureteral stenting in dogs
and cats should still be considered investigational and
that the data below are solely based on the experience of
1 group of investigators.
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10. The first report of ureteral stent placement was in 1967
in a person suffering from a malignant obstruction.28
Be-
cause of the presence of the tumor at the UVJ, access
through an antegrade percutaneous approach is typically
performed, in order to gain access down the ureter. There
are few veterinary studies or clinical cases reported in
dogs or cats with ureteral stents.a,b,c,7
Stents have been placed successfully as a long-term
treatment option in veterinary patients, contrary to our
human counterparts. Ureteral stents are most often
placed cystoscopically in dogs and, when possible, in fe-
male cats. This is done in a retrograde manner through
the ureteral orifice at the UVJ using cystoscopic and flu-
oroscopic guidance. They can also be placed antegrade,
through the renal pelvis percutaneously or surgically.
Surgical stent placement is most common in cats and this
is accomplished via pyelocentesis (antegrade), a cysto-
tomy to access the UVJ (retrograde), or through an ure-
terotomy (antegrade or retrograde).
The retrograde technique (Figure 4) typically uses
cystoscopy concurrently with fluoroscopy. An angled
hydrophilic guidewirej
is advanced into the distal ureter
from the UVJ. The wire is advanced up the distal ureter
and an open-ended ureteral catheterl
is advanced over
this wire to the distal ureter for a retrograde uretero-
pyelogram to aid in identifying any lesions, stones, or
filling defects in the ureter or renal pelvis. Once the ure-
terogram is performed the wire is readvanced up the
ureter and care is taken to bypass the obstruction and
gain access into the renal pelvis. The catheter is then
withdrawn and an indwelling double pigtail ureteral
stentk
is placed over the guidewire with 1 curl remaining
in the renal pelvis in front of the obstruction and the
other curl is pushed into the urinary bladder with the
entire shaft sitting in the ureteral lumen.
The antegrade technique (Figure 5) requires percuta-
neous or surgical pyelocentesis with a renal access nee-
dlei
or over-the needle IV catheter (18-G in dogs; 22-G in
cats). This can be performed using ultrasound, flu-
oroscopy, or via surgical palpation for guidance. The
guidewire is passed down the ureter guided by an ure-
teropyelogram, into the urinary bladder and out the
Figure 3: Feline double pigtail ureteral stents. (A) The double pigtail ureteral stent. Notice that 1 pigtail curls inside the renal pelvis and
the shaft courses down the ureteral lumen with the distal pigtail coiling inside the urinary bladder. The black catheter between the stents
is a tapered ureteral dilator that is used to aid in stent placement. (B) Notice the multiple fenestrations on the loop or shaft of the stent.
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11. urethra to have through-and-through access (flossed). This
is the typical approach for a trigonal-induced malignant
ureteral obstruction when the ureteral orifice cannot be
identified cystoscopically, or for small male dogs and male
or female cats where cystoscopy for retrograde ureteral
access is not possible. The stent is then placed in a ret-
rograde fashion over the wire, as described above, to keep
the hole in the kidney as small as possible. These proce-
dures can also be done intraoperatively when surgical
success is in question, leakage is a concern, or obstructive
neoplasia is found. Indwelling drainage is an ideal, long
term, and safe option.
At this time the success rate for ureteral stent place-
ment is 98% in dogs (n584) and 94% in cats
(n562). This has improved tremendously since the
development of a smaller diameter and different material
feline ureteral stent. This can be typically accomplished
noninvasively with fluoroscopy and cystoscopy with or
without ultrasound in most dogs, and with surgical
assistance and fluoroscopy in most cats.
One abstract on ureteral stenting in cats, where the first
47 obstructed feline ureteral units were reported (with
various types of stents)c
approximately 20% of the
obstructions were due to ureteral strictures (half due to a
previous ureteral surgery and the other half due to a
circumcaval ureter), and approximately 80% were due to
ureterolithiasis (calcium oxalate or dried solidified blood
clots). Approximately 75% of patients had evidence of
nephrolithiasis at the time of stent placement, the median
number of stones in the obstructed ureter were 6, and
approximately 10% were bilaterally obstructed. Over 80%
of patients in this population would have required 2 or
more ureterotomies to correct the ureteral obstruction,
and the majority were considered nonsurgical candidates.
Over 90% of the cats were azotemic at presentation (me-
dian creatinine 398mmol/L [ 4.5mg/dL]), while ap-
proximately 40% remained azotemic after stent placement
(median creatinine 220mmol/L [ 2.5mg/dL]).
Complications were separated into 4 categories includ-
ing procedural (during the ureteral stent placement),
peri-operative (within the first week typically during
hospitalization), short term (1wk to 1 mo) and long term
(41 mo). There were relatively few identified procedure
related complications. In patients requiring a concurrent
ureterotomy, when leakage of urine postoperatively was
anticipated, a closed-suction abdominal drain was typ-
ically placed. Leakage was rare, and when occurred typ-
ically resolved within 24 hours. No patient required a
second surgery for leakage once a stent was in place.
Peri-operative reobstruction was not seen. The peri-
operative mortality rate was under 10%, and the cause of
death or euthanasia in this patient population was due to
nonurinary causes, eg, congestive heart failure, pan-
creatitis. No patient was deemed to have died from the
Figure 4: Retrograde ureteral stent placement in a dog. (A) Cystoscopy being performed under fluoroscopic guidance as a guidewire
(black arrow) is being advanced up the ureter at the ureterovesicular junction through the working channel of the cystoscope. An
open-ended ureteral catheter is advanced over the guidewire (white arrow) for a retrograde ureteropyelogram to aid in stent
placement. (B) Guidewire being advanced up the ureter to the level of the renal pelvis (white asterisk). (C) The guidewire (black thin
arrow) being coiled inside the renal pelvis (white asterisk) as the ureteral stent (thick black arrows) is being advanced over the
guidewire through the cystoscope. (D) The double pigtail stent is pushed into the urinary bladder through the cystoscope so that each
loop is indwelling inside the patient.
Veterinary Emergency and Critical Care Society 2011, doi: 10.1111/j.1476-4431.2011.00628.x
96
A.C. Berent
12. procedure or as a complication from ureteral disease.
Only approximately 5% of cats did not have a significant
improvement in the serum creatinine concentration after
ureteral decompression with a stent. Those few patients
went on to either succumb to renal azotemia or receive a
renal transplantation.
Figure 5: Antegrade ureteral stent placement in a cat with bilateral nephrostomy tubes. (A) Percutaneous nephrostomy access via
an antegrade ureteropyelogram. A guidewire (black arrow) (0.018 in.) being advanced through the nephrostomy catheter and is
advanced down the ureter, around the stones, under fluoroscopic guidance. This patient also has a pigtail nephrostomy tube. (B)
Guidewire (black arrow) being advanced down the ureter. (C) Guidewire being advanced through the ureterovesicular junction and
out the urethra in a male cat. (D) The guidewire is through-and-through and is straight from the renal pelvis out the urethra. (E) The
open-ended ureteral dilator (white arrow heads) is being advanced over the guidewire in a retrograde manner. (F) Double pigtail
ureteral stent (white arrow) being advanced inside the renal pelvis and coiled inside the urinary bladder. (G) A lateral radiograph
after stent placement (white arrows) in feline patient after the nephrostomy tube was removed, bypassing the multiple ureteroliths
and nephroliths.
Veterinary Emergency and Critical Care Society 2011, doi: 10.1111/j.1476-4431.2011.00628.x 97
Image-guided interventions in ureteral obstructions
13. There were few short-term (from 2wk to 1 mo) com-
plications documented including dysuria (in a minority
of cats and this was typically self-limiting within 2–14 d
of onset). Patients that failed to improve received a short
course of glucocorticoids and signs improved in nearly
all of them. The long-term (41 mo postoperative) com-
plications were less serious and included pollakiuria
( 17%), stent migration ( 5%), ureteritis ( 3%), tissue
in-growth on the stent ( 7%), chronic mild hematuria
( 10%), ureterovesicular reflux ( 1%), and urinary tract
infections ( 20%). All of these complications were rare
but clients should be aware of the risks. Nearly all of
these complications were manageable with either med-
ical therapy or a minor outpatient procedure, and none
were deemed related to patient mortality.
Stent encrustation is the major complication observed in
people but this has not been appreciated in the veterinary
patients. Typically, stent mineralization in people is asso-
ciated with encrustation and is indicated on abdominal
radiographs as mineralization of the stent material cover-
ing it with stone debris. This makes it become obstructed
and extremely difficult to remove. This has not been ob-
served in any of the canine or feline stented patients on
routine radiography. Interestingly, the ureters remained
patent long term in nearly all cats with the longest stent in
place for over 4 years. No patient to date is deemed to
have died of ureteral-related disease and to date only 5%
of cats died of progressive CKD within the time span of
this study (median 4380d; as most are still alive).
The complications observed in dogs were few in all
time periods (peri-operative, short- and long term). These
included stent migration (o5%), stent occlusion (o5%),
urinary tract infections (o10%). Dysuria is much less
common in dogs than in cats after stent placement and
both species are typically glucocorticoid responsive
if necessary.
These preliminary data would suggest that ureteral
stenting in both dogs and cats are safe and effective re-
sulting in immediate decompression of the renal collection
system. Few major procedural or peri-operative compli-
cations occurred, particularly in dogs, but the learning
curve was steep. The equipment has dramatically im-
proved over the past 4 years making stent placement less
complicated and faster. In cats long-term stent exchange
or manipulation may be necessary if a ureteral reaction or
stent migration occurs, but this is relatively uncommon.
All owners should be prepared for ‘stent upkeep.’ Readers
should understand that feline ureteral stent placement is
technically challenging and care should be taken before
attempting this procedure in practice.
A new device called SUB (Figure 6) is currently under
investigation for the treatment of feline ureteral obstruc-
tions when stent placement is either not possible or has
failed. The placement of nephrostomy tubes, as described
above, is useful when renal pelvic drainage is required.
The biggest limitation is the externalized drainage,
requiring careful management and hospitalization to pre-
vent infection and dislodgement. The development of an
indwelling ureteral bypass device using a combination of
locking-loop nephrostomy and locking-loop cystostomy
catheters allows a nephrostomy tube to remain indwell-
ing. In people, a different type of ureteral bypass has been
demonstrated to improve the quality of life and reduce the
complication rates when compared with externalized
nephrostomy tubes, and have remained in situ long term
when compared with the chronic encrustations seen with
indwelling ureteral stents.47,48
This device is placed with fluoroscopic and surgical
assistance using a similar Seldinger technique as de-
scribed above for surgical nephrostomy tube placement.
Once a nephrostomy and cystostomy tube are in place a
nephropexy and cystopexy are performed and both cath-
eters are carefully tunneled under the skin and attached
onto a special port. Once both catheters are secured to the
port system the device is tested by flushing it with con-
trast material under fluoroscopic guidance ensuring no
leakage is present. Finally, the port is secured to the ven-
tral body wall to prevent migration or dislodgement. It is
Figure 6: The placement of a subcutaneous ureteral bypass (SUB). (A) A lateral radiograph of a cat with a unilateral SUB and a
contralateral ureteral stent. There is a nephrostomy catheter and cystostomy catheter connected to a vascular access port SC using
a male-to-male adaptor port (white arrow). (B) Surgical picture of the SUB that is being secured SC to the port (yellow arrow).
(C) Injection of the SUB using fluoroscopic guidance through the SC port (white). Notice a Huber needle being used to inject the port
resulting in a nephrogram, cystogram and ureterogram. Because of contralateral stent patency there is contrast filling the contralateral
renal pelvis.
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98
A.C. Berent
14. important to remember that this device can be accessed in
the future for either sampling or flushing the system, and
this should only be done using a Huber needle. Care
should be taken in performing a cystocentesis and that
this should never be performed from the side of the SUB
and should only be performed using ultrasound guid-
ance. The need for SUB flushing through the port is rarely
necessary, but can be performed using a 22-G Huber nee-
dle.m
The skin over the port should be clipped of fur and
asceptically prepared. A Huber needle on an extension set
with a 3-way stopcock is used with 1 empty syringe for
urine sampling and 1 syringe filled with 50% contrast
material. Under fluoroscopic guidance the port can be
flushed and evacuated to ensure no encrustation is pres-
ent and full patency is maintained (Figure 6).
The author has performed this procedure in 20 cats
to date for various reasons, most commonly for prox-
imal ureteral strictures. In a recent abstractn
all patients
were assessed for patency, and with median follow-up
period of 1 year, all were deemed patent and all
patients had a decrease in the creatinine concentration.
No SUB was seen to encrust or obstruct and they were
well tolerated. With this procedure there were a few
peri-operative complications including nephrostomy
site leakage due to the breakdown of the nephropexy,
leakage at the junction of 1 catheter to the port, and
SUB occlusion with a blood clot, which was relieved
with the infusion of 1 mg of tissue plasminogen acti-
vator. Leaking catheters were able to be salvaged by
securing the catheter with stronger suture material (3-0
polydioxonone) and sterile tissue glue.o
With this
adaptation no further leakage has been documented
in cases thus far. To this point there were no short- or
long-term complications in this small patient popula-
tion. Overall, the use of a SUB for cats with a ureteral
obstruction can be considered a functional option
when other traditional therapies have failed or are
contraindicated. The author considers this a salvage
procedure as complications are not common, but can
be severe if they occur and are typically procedure
related. Further investigation into the use of this device
in both cats and dogs is underway.
After placement of any device a 2-week course of a
broad spectrum antimicrobial therapy is typically rec-
ommended. Routine urinary tract ultrasonography and
radiography focusing on the renal pelvis diameter,
stent location, ureteral diameter, and SUB catheters are
performed to assure there is no evidence of migration,
occlusion, or encrustation. Bacterial urine cultures
should be obtained every 3 months for the first year
then every 6 months thereafter. Based on guidelines in
people, ureteral stents are traditionally meant to be re-
moved whenever possible and this has been extrapo-
lated to veterinary medicine as well. This is often the
case for dogs but not cats. Long-term complications
with ureteral stenting in both dogs and cat, if they oc-
cur, are typically minor, and should be anticipated and
monitored for.
Extracorporeal shock-wave lithotripsy is another
minimally invasive alternative for the removal of uret-
eral calculi.1–3
ESWL delivers external shockwaves
through a water medium directed under fluoroscopic
guidance in 2 planes. The stone is shocked anywhere
from 1,000 to 3,500 times at different energy levels to
allow for implosion and powdering. The debris is then
left to pass down the ureter into the urinary bladder
over a 1–2-week period (Figure 7). This procedure can
be performed safely for ureteroliths smaller than 5 mm
in dogs and 3–5 mm in cats. For larger stone burdens
an indwelling double pigtailed ureteral stent is placed
before ESWL to aid in stone debris passage, ureteral
imaging, and immediate relief of the ureteral obstruc-
tion. For stones of larger sizes, or those imbedded in
the ureteral mucosa, other minimally invasive options
like a PCNUL may be necessary.
PCNUL is a minimally invasive procedure where an
antegrade nephroureteroscopy is performed via renal
access.25–27
The endoscope is advanced over a guide-
wire wire, down the ureter and ureteroscopic evalua-
tion is performed. If a stone is present a stone basket
can be used to remove the stone through the access
sheath, or broken with the laser lithotrite. This is rarely
necessary in veterinary medicine.
Ureteroscopy is possible in dogs larger than approx-
imately 20 kg. This procedure is difficult to perform in
dogs through a normal ureteral orifice, as the ureter in
a normal dog is o2 mm and the smallest ureteroscope
is approximately 2.5 mm. Ureteral access is obtained
via cystoscopy, as described above with a guidewire
being advanced into the renal pelvis (Figure 8). The
flexible ureteroscope is then advanced over the guide-
wire into the ureter under fluoroscopic and endoscopic
guidance. Once the cause of the obstruction is identi-
fied it can then be treated appropriately (eg, laser
lithotripsy for stone disease or balloon dilation for a
ureteral stricture).
Postoperative management: Postoperative care is
critically important in patients with ureteral obstruc-
tions. All patients should be monitored carefully. Cats
are at particularly high risk of developing severe post-
obstructive diuresis (sometimes exceeding 4100 mL/h
of urine production) and therefore are at a high risk for
fluid overload. In the author’s experience, the majority
of patients that develop congestive heart failure after
their procedure (usually 2–5 d later) have a normal
echocardiogram before anesthesia. For this reason all
cats are treated as if they have heart disease, or at a high
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Image-guided interventions in ureteral obstructions
15. risk of fluid overload, and are monitored with central
venous pressures, serial body weights, and urine out-
put measurements to ensure they are not becoming
fluid overloaded. The fluid rate is kept as conservative
as possible to ensure proper hydration, cardiovascular
stability, and improving azotemia. Care is taken to
maintain an appropriate fluid balance using enteral
hydration when possible (ie, via feeding tubes). Our
recommendation is to place an esophagostomy tube in
all cats with ureteral obstruction during their decom-
pressive procedure. They are maintained on enteral
water, if tolerated, during hospitalization at 60–
120 mL/kg/d. If the urine production is above this rate
then they are given 0.45% saline with 2.5% dextrose at
60 mL/kg/d IV. If the urine production exceeds the
combination of this volume then they are further
matched with a balanced electrolyte replacement fluid.
Electrolyte and creatinine concentrations are followed
carefully to prevent the development of hyponatremia.
As long as the patient is cardiovascularly stable, and
Figure 8: Retrograde ureteroscopy in a female dog. (A) Using cystoscopic guidance the ureter is cannulated with a guidewire and
ureteral catheter for a retrograde ureteropyelogram. (B) A guidewire (black arrows) is up the ureter as a ureteral dilator (white
arrowhead) is advanced over the guidewire to aid in acceptance of the ureteroscope. (C) Ureteral dilator traveling up the ureter
(white arrow). (D) Ureteroscope (white arrows) that is up the ureter and inside the renal pelvis.
Figure 7: Extracorporeal shock wave lithotripsy (ESWL) in a dog with multiple ureteroliths. (A) The ESWL machine with the dog in
lateral recumbency under general anesthesia. The dry lithotrite is sitting above the dog’s ureter. (B) A lateral radiograph of the
calcium oxalate ureteroliths before ESWL. (C) A lateral radiograph after a ureteral stent and ESWL was performed. Notice
the ureteral stent traveling from the renal pelvis, down the ureter, and into the urinary bladder preventing a ureteral obstruction as
the ureteroliths fragment and pass.
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100
A.C. Berent
16. the creatinine is continually declining, then the author’s
recommendation is to try and keep the patient fluid
intake slightly under the estimated or quantified urine
output (3–5%) to prevent overhydration. These recom-
mendations are based on the author’s experience as
currently, there is no evidence-based literature to for-
mulate a treatment protocol.
Follow-up management: Persistent azotemia is a
widespread problem after a successful intervention
(over 40–50% of cats and 25–50% of dogs)c,p,6,12
and
careful monitoring for renal disease progression, reob-
struction, urinary tract infections, hypertension, hyper-
phosphatemia, and device malfunction is necessary.
Fortunately, the persistent azotemia is typically within
the IRIS Stages 1–2 chronic kidney disease, allowing a
relatively long survival time. Initial reevaluation after an
intervention is typically at 1–2 week intervals, then at 1
month, and every 2–3 months thereafter for 1–2 years,
then every 6 months thereafter. Typical evaluation en-
tails a CBC, biochemical profile, thyroid hormone con-
centration (cat), urinalysis, urine bacterial culture, urine
protein:creatinine ratio (cats), blood pressure, abdominal
radiograph, and abdominal sonography focusing on the
urinary tract. Appropriate management of CKD is often
necessary and may involve diet changes, the use of
phosphorus binders, antacids, potassium citrate (for cal-
cium oxalate stone formers), and angiotensin-converting
enzyme inhibitor if proteinuria is present.49,50
Prognosis: The prognosis for renal recovery and
persistence of patency after a ureteral obstruction is re-
lieved is variable depending upon the chronicity of the
obstruction, the species, the cause for the obstruction,
the method of fixation, the degree of obstruction, and
the postoperative care. Considering the data in normal
dogs demonstrate a dramatic loss of renal function
within 7 days16,18
and little recovery is seen after 40
days,18
timing appears to be critically important for re-
nal recovery and a ureteral obstruction should be
treated as an emergency. The data also suggest that re-
covery can take weeks to months to occur, so being
patient and giving the kidney time for recovery is nec-
essary.16,18
The author has noted dramatic improve-
ments in creatinine concentrations 4–6 months after
ureteral decompression. The resolution of hydroureter
and hydronephrosis is typically observed quickly after
resolution of the obstruction and should be followed
routinely.a,22
Interestingly, in the over 75 cats that had
ureteral stents placed in the author’s practice, only 5%
of them did not experience a dramatic return of renal
function. There was no clear documented risk factor
(eg, renal pelvis size, kidney size, renal Doppler flow on
ultrasonography, presence of anemia, degree of azote-
mia, chronicity of obstruction) that was predictive of
renal outcome and ultimate stable creatinine concen-
trations in this large group of cats.c
In the 16 dogs reported after surgical management of
ureteral calculi12
the median survival time was 904
days (range 2–1,876) and the mortality rate was 25%.12
An additional 2 dogs required a second surgery. With
the advent of ESWL for canine ureteroliths the out-
comes are superior in the limited number of cases re-
ported with an extremely low morbidity and mortality
rate. In one study of 32 dogs with renal or ureteral
calculi there was a 90% success rate, although 30% of
dogs required more than 1 ESWL treatment.3
In the
author’s experience, with concurrent ureteral stenting,
o15% of dogs required a second treatment.
In the 153 cats reported,6
of which 89 had a surgical
intervention and 52 had medical management alone,
there was an approximately 30% major postoperative
complication rate (eg, leakage, stricture, reobstruction)
and approximately 20% peri-operative mortality rate.
Thirty-three percent of cats treated medically died within
1 month of hospitalization. The mortality rate was as
high as 39% for those patients requiring hemodialysis or
a nephrostomy tube placement before surgery. Postoper-
atively 40% of cats had a ureteral obstruction recurrence,
and 86% of these cats had nephroliths at the time of the
first surgery, suggesting that nephrolithiasis could pre-
dispose patients to future ureteral obstructions.6
The current recommended treatment in our practice
is ESWL for dogs with ureteral obstructions (with or
without a concurrent ureteral stent) and a ureteral stent
in cats if they have concurrent nephroliths, multiple
ureteroliths, are considered a poor surgical candidate,
or have a history of previous stone surgery. These op-
tions are associated with the lowest morbidity and
mortality rates to date. For cats with ureteral strictures,
particularly those at the ureteropelvic junction, a SUB
is typically recommended if traditional surgical treat-
ment is declined.
Conclusions
The ureter is a frustrating area to gain access to for both
diagnostic and therapeutic purposes. With the recent
advances in veterinary interventional endourologic
techniques,a,b,c,e,f,n,1–3
diagnosis and treatment has
become less invasive and can often take place simul-
taneously. Proper training and the availability of
specialized equipment is required to help these proce-
dures become more available in the future. With these
new modalities in veterinary medicine, it is hoped that
better alternatives for these problematic conditions will
be identified, as has been the case in human medicine.
Ureteral diversion is the current treatment of choice in
human medicine and is becoming similar in our prac-
Veterinary Emergency and Critical Care Society 2011, doi: 10.1111/j.1476-4431.2011.00628.x 101
Image-guided interventions in ureteral obstructions
17. tice as well. It is important to remain cognizant that
much of the data in this review are still largely consid-
ered investigational but the future for these techniques
clearly holds great promise.
Footnotes
a
Berent A, Weisse C, Bagley D, Casale P. Ureteral stenting for benign and
malignant disease in dogs and cats (abstr). Vet Surgery 2007; 36(6): E1–
E29.
b
Zaid M, Berent A, Weisse C, et al. Feline ureteral strictures: 10 cases
(abstr). Am Coll Vet Intern Med 2010; 24:660–795.
c
Berent A, Weisse C, Bagley D, et al. Ureteral stenting for feline ureteral
obstructions: technical and clinical outcomes (abstr). Renal Week 2010.
d
Forman MA, Francey T, Fischer JR, et al. Use of glucagon in the
management of acute ureteral obstruction in 25 cats (abstr). Am Coll Vet
Intern Med 2004; 18(3): 375–460.
e
Berent A, Weisse C, Bagley D, et al. The use of locking-loop
nephrostomy tubes for ureteral obstructions in dogs and cats (abstr).
Am Coll Vet Surgeons 2010; 39:E30.
f
Berent A, Weisse C, Bagley D. The use of a subcutaneous ureteral bypass
for feline ureteral obstructions: 13 cases (abstr). World Congress
Endourol 2010.
g
Omnipaque, Iohexol 240mg/mL, GE Healthcare, Princeton, NJ.
h
Infiniti 6-Fr Locking loop drainage catheter, Infiniti Medical LLC,
Malibu, CA.
i
Dawson Meuller 5-Fr Locking loop drainage catheter, Cook Medical,
Bloomington, IN.
j
Disposable Trocar Needle, 18-G 15 cm, Cook Medical.
k
Angle-tipped hydrophilic 0.035 in. guidewire, Infiniti Medical LLC.
l
Vet Stent, Double pigtail Ureteral stent, Infiniti Medical LLC.
m
Open-ended ureteral catheter, Cook Medical.
n
Huber needle, 22-G, Access Technololgy, Skokie, IL.
o
Sterile cyanoacrylate, Abbott Animal Health, Abbott Park, IL.
p
Berent A, Weisse C, Bagley D, et al. Ureteral stenting for obstructive
ureterolithiasis (abstr). Am Coll Vet Inter Med 2009.
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