This document provides an overview of nutritional genomics, which combines molecular biology, genetics, and nutrition. Nutritional genomics examines how diet, nutrients, and food components interact with an individual's genetic makeup to influence health and disease. It discusses key concepts like nutrigenomics, which focuses on how nutrients affect genes and metabolic processes, and nutrigenetics, which examines how genetic variations influence interactions between diet and health. The document also outlines some tools and techniques used in nutritional genomics, such as analyzing single nucleotide polymorphisms to understand individual responses to nutrients.
Nutrigenomics is the application of genomics to nutritional research to understand how foods and dietary components influence gene expression. It studies the interactions between nutrition, genes, and health on a genome-wide scale. The goals of nutrigenomics are to identify dietary signals, understand how they interact with genes and signaling pathways, characterize target genes, and use this information to develop personalized diets that can help prevent diseases. Future applications include using nutrigenomics approaches to better understand polygenic diseases and create customized diets based on an individual's genetic profile.
This document discusses nutrigenomics, which is the study of how genes are affected by nutrients and dietary components. It covers how individual genetic variations influence nutrient metabolism and disease risk, with the goal of developing personalized diets. Key applications of nutrigenomics discussed include cardiovascular disease, bone health, diabetes, Alzheimer's, and cancer. Advances in high-throughput omics technologies and bioinformatics are enabling more comprehensive analysis of gene-diet interactions.
This presentation discusses nutrigenomics, which is the study of how genes interact with nutrition, especially in preventing and treating disease. Nutrigenomics is driven by new technological tools that provide a more complex understanding of how food components interact with biochemical networks. The presentation emphasizes the identification of novel biomarkers for inflammatory diseases and the role of the human microbiome. It also discusses nutrigenetics, nutrigenomics, and epigenetics in personalized nutrition approaches. Individual genetic profiles affect nutrient requirements and responses to diet and lifestyle interventions. Advances in genetic science are enabling more personalized nutrition solutions to emerging public health problems by reducing nutrition-related disease risk and prevalence through approaches like nutrigenomics, metabolomics, and functional food
This document discusses nutrigenomics, which examines how diet interacts with an individual's genes and health. It describes how macronutrients and micronutrients can influence gene expression and molecular pathways related to energy homeostasis, nutrient absorption, cell proliferation, growth, immunity and normal body function. Specific examples are given of how fatty acids and glucose impact liver and adipose gene expression related to metabolism. The document also outlines techniques used in nutrigenomics research like RT-PCR, microarrays, and reporter systems that allow analysis of gene expression and regulation in response to dietary components.
Nutrigenetics: Possibilities and limitations in the treatment of overweight...Diana Gessner
1) The document discusses nutrigenetics and its potential role in treating overweight and obesity. It outlines several candidate genes associated with obesity like FTO and genes involved in the leptin/melanocortin pathway.
2) Large genome-wide studies have identified hundreds of genetic loci associated with obesity but genetics only accounts for a small percentage of BMI variation. Environmental factors are still the major driver of obesity.
3) While leptin therapy reduced weight in leptin-deficient individuals, it did not significantly reduce weight in common obesity cases. Further research is still needed to determine nutrigenetic approaches for obesity treatment and prevention.
This document discusses nutrigenomics, which is defined as the study of how foods and their constituents affect gene expression. It provides definitions of nutrigenomics and related terms like nutrigenetics, epigenetics, and single nucleotide polymorphisms (SNPs). The document also examines how nutrigenomics research can provide insights into gene-diet interactions and their relationships to diseases like cancer, cardiovascular disease, obesity, and type 2 diabetes. Finally, it discusses some advantages and disadvantages of nutrigenomics as well as future directions for this area of research.
This document provides an overview of nutritional genomics, which combines molecular biology, genetics, and nutrition. Nutritional genomics examines how diet, nutrients, and food components interact with an individual's genetic makeup to influence health and disease. It discusses key concepts like nutrigenomics, which focuses on how nutrients affect genes and metabolic processes, and nutrigenetics, which examines how genetic variations influence interactions between diet and health. The document also outlines some tools and techniques used in nutritional genomics, such as analyzing single nucleotide polymorphisms to understand individual responses to nutrients.
Nutrigenomics is the application of genomics to nutritional research to understand how foods and dietary components influence gene expression. It studies the interactions between nutrition, genes, and health on a genome-wide scale. The goals of nutrigenomics are to identify dietary signals, understand how they interact with genes and signaling pathways, characterize target genes, and use this information to develop personalized diets that can help prevent diseases. Future applications include using nutrigenomics approaches to better understand polygenic diseases and create customized diets based on an individual's genetic profile.
This document discusses nutrigenomics, which is the study of how genes are affected by nutrients and dietary components. It covers how individual genetic variations influence nutrient metabolism and disease risk, with the goal of developing personalized diets. Key applications of nutrigenomics discussed include cardiovascular disease, bone health, diabetes, Alzheimer's, and cancer. Advances in high-throughput omics technologies and bioinformatics are enabling more comprehensive analysis of gene-diet interactions.
This presentation discusses nutrigenomics, which is the study of how genes interact with nutrition, especially in preventing and treating disease. Nutrigenomics is driven by new technological tools that provide a more complex understanding of how food components interact with biochemical networks. The presentation emphasizes the identification of novel biomarkers for inflammatory diseases and the role of the human microbiome. It also discusses nutrigenetics, nutrigenomics, and epigenetics in personalized nutrition approaches. Individual genetic profiles affect nutrient requirements and responses to diet and lifestyle interventions. Advances in genetic science are enabling more personalized nutrition solutions to emerging public health problems by reducing nutrition-related disease risk and prevalence through approaches like nutrigenomics, metabolomics, and functional food
This document discusses nutrigenomics, which examines how diet interacts with an individual's genes and health. It describes how macronutrients and micronutrients can influence gene expression and molecular pathways related to energy homeostasis, nutrient absorption, cell proliferation, growth, immunity and normal body function. Specific examples are given of how fatty acids and glucose impact liver and adipose gene expression related to metabolism. The document also outlines techniques used in nutrigenomics research like RT-PCR, microarrays, and reporter systems that allow analysis of gene expression and regulation in response to dietary components.
Nutrigenetics: Possibilities and limitations in the treatment of overweight...Diana Gessner
1) The document discusses nutrigenetics and its potential role in treating overweight and obesity. It outlines several candidate genes associated with obesity like FTO and genes involved in the leptin/melanocortin pathway.
2) Large genome-wide studies have identified hundreds of genetic loci associated with obesity but genetics only accounts for a small percentage of BMI variation. Environmental factors are still the major driver of obesity.
3) While leptin therapy reduced weight in leptin-deficient individuals, it did not significantly reduce weight in common obesity cases. Further research is still needed to determine nutrigenetic approaches for obesity treatment and prevention.
This document discusses nutrigenomics, which is defined as the study of how foods and their constituents affect gene expression. It provides definitions of nutrigenomics and related terms like nutrigenetics, epigenetics, and single nucleotide polymorphisms (SNPs). The document also examines how nutrigenomics research can provide insights into gene-diet interactions and their relationships to diseases like cancer, cardiovascular disease, obesity, and type 2 diabetes. Finally, it discusses some advantages and disadvantages of nutrigenomics as well as future directions for this area of research.
Nutrigenomics is the science that examines the response of individuals to food compounds using post-genomic and related technologies (e.g. genomics, transcriptomics, proteomics, metabol/nomic etc.). The long-term aim of nutrigenomics is to understand how the whole body responds to real foods using an integrated approach termed 'systems biology'. The huge advantage in this approach is that the studies can examine people (i.e. populations, sub-populations - based on genes or disease - and individuals), food, life-stage and life-style without preconceived ideas.
This document provides an overview of Galvus (vildagliptin) and discusses pancreatic islet dysfunction in type 2 diabetes. It notes that both insufficient insulin production and excessive glucagon secretion from alpha cells contribute to hyperglycemia in type 2 diabetes. The document reviews evidence that beta cell function deteriorates over time in type 2 diabetes despite stable insulin sensitivity, and that early glycemic control can reduce complications and have long-term legacy effects on cardiovascular outcomes compared to late control.
This document discusses medical nutrition therapy for diabetes, including nutrition assessment goals, recommendations, considerations for special populations like those who are overweight or have type 1, type 2, or gestational diabetes. It covers assessing nutrition needs, monitoring carbohydrates, meal planning strategies like portion control and carbohydrate counting, and basic follow-up nutrition advice and resources for patients. The conclusion questions if a perfect eating plan exists for diabetes management.
The document discusses the role of nutrition in cardiovascular disease. It outlines nutrition guidelines for conditions like hypercholesterolemia and hypertriglyceridemia. Nutrition therapy aims to lower total and LDL cholesterol through a diet low in saturated fat and cholesterol. Enteral or parenteral nutrition support may be needed for patients with congestive heart failure or after cardiac surgery to meet increased calorie and protein needs and avoid weight loss. Nutrition also plays a role in managing cardiovascular risk factors in diabetes.
the new emerging field of science that is nutrigenomics can deal with the issues of health and improve out health with the simple tools by understanding the risk and the baic genome of a person
The document discusses liver disease and nutrition. It begins by reviewing the functions of the liver and various liver diseases. It then discusses nutritional features of end-stage liver disease and nutritional assessment and management guidelines. Specific topics covered include neurological symptoms associated with liver disease, nutritional assessment tools for patients with end-stage liver disease, daily energy expenditure calculation methods, progression of liver disease, and ESPEN guidelines on enteral and parenteral nutrition for various liver diseases.
Nutrigenomics is an emerging scientific discipline that studies the effects of foods and dietary components on gene expression. It explores how nutrients and bioactive compounds in food can turn genes on and off and influence our health. Some key points covered in the document include:
- Nutrigenomics uses tools from fields like genetics, molecular biology, and genomics to study nutrient-gene interactions.
- Certain nutrients consumed during critical periods of development can modulate gene imprinting and influence long-term health outcomes.
- Omega-3 fatty acids from foods like fish have been shown to downregulate genes associated with heart disease and upregulate genes related to cardiovascular health.
- Nutrigenomics research is providing insights into personalized
Nutrigenomics attempts to study how nutrition influences gene expression and metabolic pathways. It examines the dietary signatures - patterns of gene, protein, and metabolite expression - produced in cells and tissues in response to specific nutrients. Nutrigenomics seeks to understand how these signatures impact homeostasis and may help identify early biomarkers for conditions like insulin resistance. It takes a holistic approach using omics technologies like transcriptomics, proteomics, and metabolomics. Nutrigenomics also examines how genetics and environment interact to influence nutritional needs and responses.
A ketogenic diet involves drastically reducing carbohydrate intake and replacing it with fat to induce a metabolic state called ketosis where the body burns fat for energy instead of carbohydrates. This can help reduce blood sugar and insulin levels and cause significant weight loss, especially from the abdominal area. To enter ketosis, one must limit net carbs to 20-50 grams per day by eating foods low in carbs like meat, fish, eggs, non-starchy vegetables, nuts and seeds, and high-fat dairy while avoiding foods high in carbs like grains, fruits, legumes, and sugar. Benefits of a keto diet include reduced appetite, weight loss, improved cholesterol levels, lower blood pressure and reduced risk
This document discusses medical nutrition therapy for diabetes. It outlines the major components of diabetes treatment as management of diabetes through nutrition recommendations and interventions. It describes expected outcomes of medical nutrition therapy for diabetes such as reductions in A1C and LDL-C. The document discusses nutrition therapy strategies for type 1 and type 2 diabetes, including carbohydrate intake, fiber, sweeteners, and glycemic index. It provides guidelines on integrating insulin therapy with dietary and activity patterns and adjusting insulin doses based on carbohydrate intake.
Intermittent fasting and metabolic syndromefathi neana
Dr. Fathi Neana discusses metabolic syndrome and its impact on the musculoskeletal system. Metabolic syndrome is reaching epidemic proportions and is associated with obesity, diabetes, gout, and other conditions that can cause surgical difficulties and complications. Intermittent fasting is presented as a potential strategy for correcting metabolic abnormalities and managing conditions associated with metabolic syndrome like type 2 diabetes.
Nutrigenomics is the study of how nutrients and foods affect gene expression. It examines the interactions between an individual's genetics, diet, and health. The summary discusses three key areas:
1. Nutrigenomics research focuses on preventing chronic diseases like cancer, cardiovascular disease, and obesity by deactivating disease signaling pathways through nutrient supplements.
2. Specific nutrients can prevent these diseases. For example, polyunsaturated fatty acids can prevent cancer by regulating genes involved in cell growth, inflammation, and proliferation.
3. Personalized nutrition is an outcome of nutrigenomics and can be used to promote health through prevention and treatment of diseases, weight control, and immunity improvement.
The document discusses the relationship between nutrition and cancer prevention. Some key points:
- One third of cancer deaths in the US are attributed to lifestyle factors like nutrition.
- Epidemiological studies link certain foods like fruits/vegetables to lower cancer risk, while high fat diets and obesity are associated with higher risks.
- Specific foods like fiber, carotenoids, and lycopene from plants may protect against cancer through antioxidant effects and influencing hormone levels/cell growth.
- While supplements like beta-carotene require more research, diets high in a variety of plant-based foods are recommended for cancer prevention.
Importance of nutritional management during hospitalizationBushra Tariq
The document discusses the importance of nutritional management for hospitalized patients. It notes that up to 50% of hospitalized patients experience some degree of malnutrition. Providing adequate nutrition support through enteral or parenteral nutrition can improve patient outcomes, reduce recovery time, and lower healthcare costs. The document provides guidelines for estimating caloric and protein needs for critically ill patients and recommends early enteral nutrition within 24-48 hours when possible to support gut health and integrity.
This document provides an overview of a continuing medical education (CME) program on the use of vildagliptin in managing type 2 diabetes mellitus (T2DM). The presentation covers the global burden of diabetes, pathophysiology of T2DM, limitations of current oral therapies, the incretin system, and the mechanisms and effects of DPP-4 inhibitors like vildagliptin. It discusses how vildagliptin improves pancreatic beta cell function and glucose control by prolonging the actions of incretins GLP-1 and GIP. The presentation also highlights the differences between incretin mimetics and DPP-4 inhibitors.
This document discusses the relationship between nutrition and mental health. It provides an overview of common medications used to treat mental health conditions like depression and anxiety. It emphasizes using a whole-foods, nutrient-dense diet and supplements like omega-3, multivitamins, and herbal remedies as part of an integrative approach to mental health. Testing methods and resources for making healthy food choices are also outlined. The document is presented by Dr. Ric Saguil to promote an alternative perspective on mental health treatment focusing on nutrition and lifestyle factors.
This document discusses obesity rates in upstate New York from 2004 to 2008. It finds that obesity among adults in the region increased dramatically during this period. The counties with the highest obesity rates each year tended to be Chautauqua, Chemung, Franklin, Seneca, and Yates counties. Obesity is linked to numerous health issues like heart disease, diabetes, and cancer. The document recommends eating healthier foods, daily exercise, and potentially surgery as ways to reduce obesity.
The document discusses low-carbohydrate ketogenic diets and their role in weight loss. It explains that low-carb diets induce ketosis, using fat and protein for fuel instead of carbohydrates. This leads to initial rapid weight loss from water loss. Long-term weight loss is achieved through fat loss if the diet is nutritionally complete and exercise is maintained. However, very low carb intake may cause side effects like increased uric acid and decreased cognitive function if not medically supervised long-term.
This document provides information on carbohydrate counting for diabetes management. It defines carbohydrate counting as a method to calculate grams of carbohydrates consumed. The goals are to maintain consistent carb intake, increase dietary flexibility, and manage blood glucose. Carbohydrates are broken down into glucose and absorbed into the bloodstream. Foods like fruits, starches, grains and milk contain carbs. Counting carbs involves identifying carb-containing foods and determining servings equal to 15 grams of carbs. Tools like mobile apps, food labels and visual guides can help estimate carb amounts. Physical activity also impacts blood sugar, so carb intake may need adjustment based on activity level and intensity.
Inadequate long-chain omega-3 fatty acid status has a substantial impact on our health. Human RCT, observational, in vitro and in vivo animal studies all demonstrate that omega-3 fats from fish improve inflammatory regulation and its associated conditions. Yet, due to inconsistency in findings, the validity of omega-3 fatty acids as ‘treatments’ has been brought into question in the reporting of studies. To date, few studies have monitored the correlation between omega-3 dose, subsequent cellular enrichment of these fatty acids and clinical outcomes.
In this webinar, Dr Bailey presents the latest evidence for the importance of a biomarker-based, personalised approach to omega-3 treatment – one that significantly improves consistency in clinical outcomes and offers an antidote to the ‘one-size fits all’ approach that is responsible for significant individual variations in response in many published studies.
The document discusses nutrigenomics and nutrigenetics. It begins with important terms related to omics fields like genomics, nutrigenomics, and epigenetics. It then provides a basic understanding of nutrigenomics and nutrigenetics, including how genetic diversity and environmental factors affect nutrient metabolism and health outcomes. The goals of nutrigenomics are discussed, including customizing nutrition based on an individual's genetics. Experimental approaches like genomics, transcriptomics and metabolomics are used to study these fields. Examples are provided on how nutrigenomics has clarified roles of specific dietary factors and potential applications in disease prevention.
Nutrigenomics is the science that examines the response of individuals to food compounds using post-genomic and related technologies (e.g. genomics, transcriptomics, proteomics, metabol/nomic etc.). The long-term aim of nutrigenomics is to understand how the whole body responds to real foods using an integrated approach termed 'systems biology'. The huge advantage in this approach is that the studies can examine people (i.e. populations, sub-populations - based on genes or disease - and individuals), food, life-stage and life-style without preconceived ideas.
This document provides an overview of Galvus (vildagliptin) and discusses pancreatic islet dysfunction in type 2 diabetes. It notes that both insufficient insulin production and excessive glucagon secretion from alpha cells contribute to hyperglycemia in type 2 diabetes. The document reviews evidence that beta cell function deteriorates over time in type 2 diabetes despite stable insulin sensitivity, and that early glycemic control can reduce complications and have long-term legacy effects on cardiovascular outcomes compared to late control.
This document discusses medical nutrition therapy for diabetes, including nutrition assessment goals, recommendations, considerations for special populations like those who are overweight or have type 1, type 2, or gestational diabetes. It covers assessing nutrition needs, monitoring carbohydrates, meal planning strategies like portion control and carbohydrate counting, and basic follow-up nutrition advice and resources for patients. The conclusion questions if a perfect eating plan exists for diabetes management.
The document discusses the role of nutrition in cardiovascular disease. It outlines nutrition guidelines for conditions like hypercholesterolemia and hypertriglyceridemia. Nutrition therapy aims to lower total and LDL cholesterol through a diet low in saturated fat and cholesterol. Enteral or parenteral nutrition support may be needed for patients with congestive heart failure or after cardiac surgery to meet increased calorie and protein needs and avoid weight loss. Nutrition also plays a role in managing cardiovascular risk factors in diabetes.
the new emerging field of science that is nutrigenomics can deal with the issues of health and improve out health with the simple tools by understanding the risk and the baic genome of a person
The document discusses liver disease and nutrition. It begins by reviewing the functions of the liver and various liver diseases. It then discusses nutritional features of end-stage liver disease and nutritional assessment and management guidelines. Specific topics covered include neurological symptoms associated with liver disease, nutritional assessment tools for patients with end-stage liver disease, daily energy expenditure calculation methods, progression of liver disease, and ESPEN guidelines on enteral and parenteral nutrition for various liver diseases.
Nutrigenomics is an emerging scientific discipline that studies the effects of foods and dietary components on gene expression. It explores how nutrients and bioactive compounds in food can turn genes on and off and influence our health. Some key points covered in the document include:
- Nutrigenomics uses tools from fields like genetics, molecular biology, and genomics to study nutrient-gene interactions.
- Certain nutrients consumed during critical periods of development can modulate gene imprinting and influence long-term health outcomes.
- Omega-3 fatty acids from foods like fish have been shown to downregulate genes associated with heart disease and upregulate genes related to cardiovascular health.
- Nutrigenomics research is providing insights into personalized
Nutrigenomics attempts to study how nutrition influences gene expression and metabolic pathways. It examines the dietary signatures - patterns of gene, protein, and metabolite expression - produced in cells and tissues in response to specific nutrients. Nutrigenomics seeks to understand how these signatures impact homeostasis and may help identify early biomarkers for conditions like insulin resistance. It takes a holistic approach using omics technologies like transcriptomics, proteomics, and metabolomics. Nutrigenomics also examines how genetics and environment interact to influence nutritional needs and responses.
A ketogenic diet involves drastically reducing carbohydrate intake and replacing it with fat to induce a metabolic state called ketosis where the body burns fat for energy instead of carbohydrates. This can help reduce blood sugar and insulin levels and cause significant weight loss, especially from the abdominal area. To enter ketosis, one must limit net carbs to 20-50 grams per day by eating foods low in carbs like meat, fish, eggs, non-starchy vegetables, nuts and seeds, and high-fat dairy while avoiding foods high in carbs like grains, fruits, legumes, and sugar. Benefits of a keto diet include reduced appetite, weight loss, improved cholesterol levels, lower blood pressure and reduced risk
This document discusses medical nutrition therapy for diabetes. It outlines the major components of diabetes treatment as management of diabetes through nutrition recommendations and interventions. It describes expected outcomes of medical nutrition therapy for diabetes such as reductions in A1C and LDL-C. The document discusses nutrition therapy strategies for type 1 and type 2 diabetes, including carbohydrate intake, fiber, sweeteners, and glycemic index. It provides guidelines on integrating insulin therapy with dietary and activity patterns and adjusting insulin doses based on carbohydrate intake.
Intermittent fasting and metabolic syndromefathi neana
Dr. Fathi Neana discusses metabolic syndrome and its impact on the musculoskeletal system. Metabolic syndrome is reaching epidemic proportions and is associated with obesity, diabetes, gout, and other conditions that can cause surgical difficulties and complications. Intermittent fasting is presented as a potential strategy for correcting metabolic abnormalities and managing conditions associated with metabolic syndrome like type 2 diabetes.
Nutrigenomics is the study of how nutrients and foods affect gene expression. It examines the interactions between an individual's genetics, diet, and health. The summary discusses three key areas:
1. Nutrigenomics research focuses on preventing chronic diseases like cancer, cardiovascular disease, and obesity by deactivating disease signaling pathways through nutrient supplements.
2. Specific nutrients can prevent these diseases. For example, polyunsaturated fatty acids can prevent cancer by regulating genes involved in cell growth, inflammation, and proliferation.
3. Personalized nutrition is an outcome of nutrigenomics and can be used to promote health through prevention and treatment of diseases, weight control, and immunity improvement.
The document discusses the relationship between nutrition and cancer prevention. Some key points:
- One third of cancer deaths in the US are attributed to lifestyle factors like nutrition.
- Epidemiological studies link certain foods like fruits/vegetables to lower cancer risk, while high fat diets and obesity are associated with higher risks.
- Specific foods like fiber, carotenoids, and lycopene from plants may protect against cancer through antioxidant effects and influencing hormone levels/cell growth.
- While supplements like beta-carotene require more research, diets high in a variety of plant-based foods are recommended for cancer prevention.
Importance of nutritional management during hospitalizationBushra Tariq
The document discusses the importance of nutritional management for hospitalized patients. It notes that up to 50% of hospitalized patients experience some degree of malnutrition. Providing adequate nutrition support through enteral or parenteral nutrition can improve patient outcomes, reduce recovery time, and lower healthcare costs. The document provides guidelines for estimating caloric and protein needs for critically ill patients and recommends early enteral nutrition within 24-48 hours when possible to support gut health and integrity.
This document provides an overview of a continuing medical education (CME) program on the use of vildagliptin in managing type 2 diabetes mellitus (T2DM). The presentation covers the global burden of diabetes, pathophysiology of T2DM, limitations of current oral therapies, the incretin system, and the mechanisms and effects of DPP-4 inhibitors like vildagliptin. It discusses how vildagliptin improves pancreatic beta cell function and glucose control by prolonging the actions of incretins GLP-1 and GIP. The presentation also highlights the differences between incretin mimetics and DPP-4 inhibitors.
This document discusses the relationship between nutrition and mental health. It provides an overview of common medications used to treat mental health conditions like depression and anxiety. It emphasizes using a whole-foods, nutrient-dense diet and supplements like omega-3, multivitamins, and herbal remedies as part of an integrative approach to mental health. Testing methods and resources for making healthy food choices are also outlined. The document is presented by Dr. Ric Saguil to promote an alternative perspective on mental health treatment focusing on nutrition and lifestyle factors.
This document discusses obesity rates in upstate New York from 2004 to 2008. It finds that obesity among adults in the region increased dramatically during this period. The counties with the highest obesity rates each year tended to be Chautauqua, Chemung, Franklin, Seneca, and Yates counties. Obesity is linked to numerous health issues like heart disease, diabetes, and cancer. The document recommends eating healthier foods, daily exercise, and potentially surgery as ways to reduce obesity.
The document discusses low-carbohydrate ketogenic diets and their role in weight loss. It explains that low-carb diets induce ketosis, using fat and protein for fuel instead of carbohydrates. This leads to initial rapid weight loss from water loss. Long-term weight loss is achieved through fat loss if the diet is nutritionally complete and exercise is maintained. However, very low carb intake may cause side effects like increased uric acid and decreased cognitive function if not medically supervised long-term.
This document provides information on carbohydrate counting for diabetes management. It defines carbohydrate counting as a method to calculate grams of carbohydrates consumed. The goals are to maintain consistent carb intake, increase dietary flexibility, and manage blood glucose. Carbohydrates are broken down into glucose and absorbed into the bloodstream. Foods like fruits, starches, grains and milk contain carbs. Counting carbs involves identifying carb-containing foods and determining servings equal to 15 grams of carbs. Tools like mobile apps, food labels and visual guides can help estimate carb amounts. Physical activity also impacts blood sugar, so carb intake may need adjustment based on activity level and intensity.
Inadequate long-chain omega-3 fatty acid status has a substantial impact on our health. Human RCT, observational, in vitro and in vivo animal studies all demonstrate that omega-3 fats from fish improve inflammatory regulation and its associated conditions. Yet, due to inconsistency in findings, the validity of omega-3 fatty acids as ‘treatments’ has been brought into question in the reporting of studies. To date, few studies have monitored the correlation between omega-3 dose, subsequent cellular enrichment of these fatty acids and clinical outcomes.
In this webinar, Dr Bailey presents the latest evidence for the importance of a biomarker-based, personalised approach to omega-3 treatment – one that significantly improves consistency in clinical outcomes and offers an antidote to the ‘one-size fits all’ approach that is responsible for significant individual variations in response in many published studies.
The document discusses nutrigenomics and nutrigenetics. It begins with important terms related to omics fields like genomics, nutrigenomics, and epigenetics. It then provides a basic understanding of nutrigenomics and nutrigenetics, including how genetic diversity and environmental factors affect nutrient metabolism and health outcomes. The goals of nutrigenomics are discussed, including customizing nutrition based on an individual's genetics. Experimental approaches like genomics, transcriptomics and metabolomics are used to study these fields. Examples are provided on how nutrigenomics has clarified roles of specific dietary factors and potential applications in disease prevention.
An extensive literature review on Nutrigenetics -A new trajectory in obesity...nutritionistrepublic
Obesity is a multifactorial disease influenced by genes and environment. Various genes involved in appetite, metabolism, and fat storage have been identified that can cause differential responses to diet. Nutrigenetics examines how genetic variations affect the interaction between diet and disease, with the goal of developing personalized diets. One study found that patients who received nutrigenetic testing and were given a personalized diet based on their genetic profile lost more weight and better maintained reductions in BMI and blood glucose levels over time compared to a control group without genetic testing. While nutrigenetics shows promise for developing targeted weight loss strategies, challenges remain in fully characterizing gene-diet interactions and implementing testing in clinical practice.
Quisper launch: 2. Personalised nutrition - Jo GoosensQuisper
Introduction to personalized nutrition from the Quisper launch event: Quality information services for personalized nutrition and lifestyle advice ( www.quisper.eu) developed during the FP7 funded QuaLiFY project.
Three trends are influencing workplace health and performance in Australia: 1) Life expectancy is increasing but health expectancy is decreasing, with the average person living their last years with disabilities. 2) Obesity rates are high, with over two-thirds of men and over half of women overweight or obese. 3) The population is aging, with one-fifth of Australians expected to be over 65 by 2020. Understanding the interaction between genes and lifestyle/environmental factors is important for preventing disease and improving occupational health. Personalized nutrition, exercise and lifestyle plans based on genetic profiles have the potential to help people maximize their health and longevity. One woman lost over 10kg and saw improvements in inflammation and biological age after following a personalized program based on her
This document discusses nutrition and genomics. It begins with an introduction to nutrigenomics, which examines how foods affect genetic expression and how an individual's genetics influence nutrient metabolism and response. It then covers nutrigenetics, nutrigenomics, and nutritional epigenomics, and how bioactive food components can influence genetic and epigenetic events. Problems in the field include food variability and the complex relationship between genes and disease. However, future potential includes developing personalized dietary interventions to prevent disease and validating product claims.
This document presents information about glutamine in nutrition management. It discusses glutamine as the most abundant amino acid in the body, which can be synthesized and is not essential to the diet. It serves various functions including protein synthesis, acid-base regulation, and as an energy source. The document outlines glutamine producers, consumers, dietary sources, metabolism, medical uses including for cancer and HIV/AIDS patients, and roles in cellular protection, gut barrier function, immune modulation, and oxidative stress. The document also discusses glutamine supplementation for athletes to boost performance and recovery.
The document discusses gene-environment interactions related to obesity. It provides the example of the Pima Indians, noting that the Pimas in Arizona have experienced an obesity epidemic in recent decades due to lifestyle changes including a higher fat diet and more sedentary lifestyle compared to their genetic relatives in Mexico who maintain a traditional diet and active lifestyle and have lower obesity rates. While genetics play a role in obesity susceptibility, the rapid increase in obesity cannot be explained by genetics alone and is likely due to environmental factors, with certain genetic profiles making individuals more vulnerable to weight gain in obesogenic environments.
Energy balance is the difference between energy intake through food consumption and energy expenditure. An imbalance where intake exceeds expenditure over time leads to weight gain as excess calories are stored as fat. Most obese individuals do not have abnormal reductions in metabolic rate. Weight regain is prevented when energy intake is reduced to match expenditures set by the body's new size and composition after weight loss.
Nutrigenomics is the study of how nutrients and other food components interact with an individual's genome to affect gene expression. It examines how diet influences cellular processes and looks at individual variability in responses to foods based on genetic makeup. The main concepts are that specific diets can modulate health and disease by impacting gene expression, genetic polymorphisms influence disease risk and diet response, and personalized diets may help reduce risk for genetically predisposed individuals. Key applications of nutrigenomics include understanding how diet relates to obesity, type 2 diabetes, cardiovascular disease, cancer, and other chronic health conditions by studying gene-diet interactions and genetic variations.
to download this presentation from this link
https://mohmmed-ink.blogspot.com/2020/12/obesity.html
obesity, causes, diagnosis, complications, treatment, prevention.
The document discusses obesity in children and adolescents. It states that 1 in 5 children are overweight or obese, and the number of obese children has more than tripled since 1985. About 80% of obese adolescents will become obese adults. Changing societal factors like increased availability of unhealthy foods, larger portions, and decreased physical activity are contributing to rising obesity rates in children. Obesity can lead to health issues like type 2 diabetes, heart disease, and liver problems. Maintaining a healthy diet and being physically active are important to prevent obesity and promote overall wellness.
Art is a creative expression that stimulates the senses or imagination according to Felicity Hampel. Picasso believed that every child is an artist but growing up can stop that creativity. Aristotle defined art as anything requiring a maker and not being able to create itself.
Service providers who receive high nutrition risk referrals, particularly Registered Dietitians, need to be knowledgeable about general and clinical pediatric nutrition as well as counselling skills for working with families and children.
This is the second of five self-directed training modules available in PowerPoint presentations that have been developed and evaluated to respond to this need
This document discusses several studies on the impact of agricultural interventions on nutrition outcomes. It finds:
1. Interventions that increased access to animal source foods like milk, meat and eggs led to improvements in child growth, cognitive development, and nutritional status.
2. A study in Ghana that provided microcredit loans, nutrition education and promoted small livestock saw reductions in food insecurity and improvements in height, weight, and intake of proteins, calcium, zinc and iron.
3. Home garden projects in Bangladesh that grew nutrient-rich plants and supported small livestock led to increased vegetable production, income, food security and consumption of micronutrient-rich foods for over 5 million people.
This document discusses nutrigenomics and nutrigenetics, which are two related but distinct fields that examine the relationship between genetics and nutrition. Nutrigenomics looks at how foods and nutrients influence gene expression, while nutrigenetics focuses on how genetic variations impact an individual's response to specific foods and nutrients. The document provides examples of how knowledge in these fields can help identify personalized diets and nutritional interventions tailored to one's genetic profile that may help prevent or treat chronic diseases like obesity, cardiovascular disease, and cancer. It also discusses some specific genetic disorders like lactose intolerance and phenylketonuria where restricting certain foods can benefit affected individuals.
The document discusses the American Dietetic Association's position that a total diet approach, which focuses on overall eating patterns over time rather than individual foods, is most important for healthy eating. It emphasizes eating a variety of nutrient-dense foods in moderation. The document also discusses how federal nutrition guidance like the Dietary Guidelines for Americans supports this total diet approach. Finally, it discusses challenges communicating nutrition information to the public and strategies for effective nutrition education campaigns.
The document discusses risk factors for eating disorders including biological, psychological, developmental, and social factors. It separates risk factors into eating-specific (direct) factors and generalized (indirect) factors. Some key eating-specific biological risks include genetics, appetite regulation, and gender. Key psychological risks include poor body image, maladaptive eating attitudes, and overvaluation of appearance. Developmental risks include identifications with body-concerned relatives/peers and trauma affecting bodily experience. Social risks include maladaptive family attitudes toward eating/weight and peer/cultural pressures regarding thinness. The document aims to provide an overview of various risk factors to better understand the development and prevention of eating disorders.
This document provides recommendations and tools for healthy eating. It discusses concepts like nutrient density, energy density, and desirable nutrition status. Tools for assessing nutrition status include anthropometric, biochemical, clinical, and dietary assessments. Principles of sensible eating include moderation, variety, and balance. The document also outlines the process of nutrition research from observations to theories and different types of research studies. Main nutrition education tools in the US include the Dietary Guidelines and MyPlate, which provide recommendations on nutrients and foods to increase or reduce based on age, gender and other factors. Food labels are also an important practical tool for evaluating foods.
We Are More Than What We Eat Dietary Interventions Depend on Sex and Genetic ...InsideScientific
To learn more visit: https://insidescientific.com/webinar/we-are-more-than-what-we-eat-dietary-interventions-depend-on-sex-and-genetic-background/
Despite evidence that sex and genetic background are key factors in the response to diet, most studies of how diet regulates metabolic health and even longevity in mice examine only a single strain and sex.
Using multiple strains and both male and female mice, Dr Lamming's team has found that improvements in metabolic health and in longevity in response to reduced levels of protein or specific amino acids strongly depend on sex and strain. While some phenotypes were conserved across strains and sexes, including increased glucose tolerance and energy expenditure, they observed high variability in adiposity, insulin sensitivity, and circulating hormones. Using a multi-omics approach, they identified mega-clusters of differentially expressed hepatic genes, metabolites, and lipids associated with each phenotype, gaining new insight into role of the energy balance hormone FG21 in the response to protein restriction.
1. Nutrigenomics is the study of how nutrients and other food components influence gene expression and health. It seeks to understand how an individual's genetic makeup determines their response to different diets.
2. Specific dietary components can modulate the balance between health and disease by directly or indirectly impacting gene expression. An individual's genetic profile, including polymorphisms in nutrient-regulated genes, affects their risk of diseases.
3. Personalized diets tailored to one's genotype may help lower disease risk in genetically predisposed groups by accounting for how genetics influence the body's response to different nutrients.
Nutrigenomics is the study of how nutrients and other food components influence gene expression and health. It considers how an individual's genetic makeup influences their response to different diets. The main concepts are that specific diets can modulate health by influencing gene expression, genetic factors affect disease risk, and personalized diets based on genetics may lower risk. Improper diets are linked to disease risk, while certain foods and chemicals can alter gene expression or genome structure. An individual's response depends on their genetic profile, like single nucleotide polymorphisms. Nutrigenomics studies seek to develop personalized diets to prevent diseases based on genetic risk factors.
Nutrigenomics the latest area of nutrition researchRamabhau Patil
Nutrigenomics is the study of how genes interact with nutrients and how this affects health. It seeks to develop personalized nutrition solutions and diets tailored to each person's DNA. While still a young science, nutrigenomics may ultimately enable personalized dietary advice and its impact on public health is expected to be significant over the next decade. Different people can respond very differently to the same diet depending on their genetic makeup, so nutrigenomics aims to determine the specific nutrient needs of individuals based on their genetic profiles.
This document discusses nutrition for cancer patients. It covers how cancer and cancer treatments can affect nutritional needs and eating habits. Some key points:
1) Cancer and treatments can cause changes in appetite, taste, digestion and the body's use of nutrients. This can lead to weight loss or gain and nutritional deficiencies.
2) Surgery, radiation and chemotherapy can directly impact eating and digestion depending on the treatment area. Common side effects include mouth sores, nausea, vomiting and diarrhea.
3) The document provides tips to address common nutritional problems like ensuring adequate calorie and protein intake during treatment, managing taste changes, and dealing with side effects like weight loss or appetite changes.
4) It also discusses
This document discusses obesity, including its definition, classification, causes, health risks, diagnosis, and management. Obesity is defined as excess body fat accumulation that negatively impacts health, and is classified using body mass index (BMI), waist circumference, and waist-to-hip ratio. Causes include genetic, environmental, and behavioral factors. Health risks associated with obesity include increased risk of diabetes, cardiovascular disease, respiratory issues, cancers, and mental health conditions. Treatment involves lifestyle modifications focusing on diet and exercise, as well as potential medication options to help with weight loss.
This document provides guidance on nutrition counseling. It discusses factors that influence malnutrition and outlines the Essential Nutrition Actions which include exclusive breastfeeding for 6 months, adequate complementary feeding starting at 6 months, appropriate nutrition care for sick children, and adequate intake of vitamins and minerals. It also discusses developing nutrition care plans, counseling on diet and nutrition for various groups like pregnant women, children, and those who are ill. Key messages include eating a variety of nutrient-dense foods, maintaining hygiene and sanitation, managing symptoms through diet, and taking medicines as prescribed.
XNN001 Lecture 2 The epidemiology of nutrition and physical activityramseyr
This document discusses the epidemiology of physical activity and nutrition in Australia. It finds that 28% of Australian adults are obese and chronic conditions account for 80% of the disease burden. National health and nutrition surveys collect self-reported data on diet, physical activity, and health indicators but methods vary over time. Nutrient intake data suggests most Australians do not meet fruit and vegetable recommendations. National physical activity guidelines recommend 30 minutes per day for adults and 60 minutes for children.
Nutrigenomics is the study of how nutrients and bioactive food components influence gene expression and how genetic variations affect individual responses to specific foods or nutrients. It seeks to understand how diet influences health and disease risk based on a person's genetic makeup. Key concepts include that specific diets can modulate health by influencing gene expression, genetic polymorphisms affect disease risk and response to diet, and personalized diets based on genetics may lower disease risk. Nutrigenomics research is providing insights into relationships between nutrition, genes, and chronic diseases like obesity, cardiovascular disease, and cancer.
This document is Stanley Lee's mySNP DNA Wellness Report, which analyzes his genetic variations to provide information about how his body processes nutrients and which nutrients he may need more of. The report finds that Stanley has a slightly high risk of impaired caffeine metabolism, meaning he is likely a slower caffeine metabolizer and may experience side effects from caffeine more easily. It also finds he has a slightly high risk of deficiencies in certain vitamins and minerals like vitamin B1, B12, iron, selenium, zinc, and monounsaturated fats. The report provides dietary and lifestyle recommendations based on these genetic results.
Nutrigenomics is the study of how nutrients and other food components influence gene expression. It seeks to understand how nutrition impacts homeostasis at the cellular and genetic levels. The main concepts are that specific diets can modulate health and disease by affecting gene expression, an individual's genetic makeup influences their response to diet and disease risk, and personalized diets based on genetics may lower risk. Nutrigenomics examines how nutrients directly or indirectly regulate genes and how genetic variations impact nutrient metabolism and disease. It studies relationships between diet, genes and chronic diseases like obesity, diabetes, cancer and cardiovascular disease.
The document discusses preventive nutrition and its role in promoting health and preventing disease. Preventive nutrition aims to help people live long, healthy lives through nutrition. It involves making dietary changes and lifestyle modifications to increase well-being, energy levels, and disease resistance. Small changes can help reduce the risk of degenerative diseases like heart disease, cancer, and diabetes. Preventive nutrition follows principles of diversity, balance and moderation in the diet. It can benefit those with conditions like allergies, heart disease risks, digestive issues, and more.
Similar to Introduction to nutrigenetics by geneobe (20)
Hypertension and it's role of physiotherapy in it.Vishal kr Thakur
This particular slides consist of- what is hypertension,what are it's causes and it's effect on body, risk factors, symptoms,complications, diagnosis and role of physiotherapy in it.
This slide is very helpful for physiotherapy students and also for other medical and healthcare students.
Here is summary of hypertension -
Hypertension, also known as high blood pressure, is a serious medical condition that occurs when blood pressure in the body's arteries is consistently too high. Blood pressure is the force of blood pushing against the walls of blood vessels as the heart pumps it. Hypertension can increase the risk of heart disease, brain disease, kidney disease, and premature death.
Health Tech Market Intelligence Prelim Questions -Gokul Rangarajan
The Ultimate Guide to Setting up Market Research in Health Tech part -1
How to effectively start market research in the health tech industry by defining objectives, crafting problem statements, selecting methods, identifying data collection sources, and setting clear timelines. This guide covers all the preliminary steps needed to lay a strong foundation for your research.
This lays foundation of scoping research project what are the
Before embarking on a research project, especially one aimed at scoping and defining parameters like the one described for health tech IT, several crucial considerations should be addressed. Here’s a comprehensive guide covering key aspects to ensure a well-structured and successful research initiative:
1. Define Research Objectives and Scope
Clear Objectives: Define specific goals such as understanding market needs, identifying new opportunities, assessing risks, or refining pricing strategies.
Scope Definition: Clearly outline the boundaries of the research in terms of geographical focus, target demographics (e.g., age, socio-economic status), and industry sectors (e.g., healthcare IT).
3. Review Existing Literature and Resources
Literature Review: Conduct a thorough review of existing research, market reports, and relevant literature to build foundational knowledge.
Gap Analysis: Identify gaps in existing knowledge or areas where further exploration is needed.
4. Select Research Methodology and Tools
Methodological Approach: Choose appropriate research methods such as surveys, interviews, focus groups, or data analytics.
Tools and Resources: Select tools like Google Forms for surveys, analytics platforms (e.g., SimilarWeb, Statista), and expert consultations.
5. Ethical Considerations and Compliance
Ethical Approval: Ensure compliance with ethical guidelines for research involving human subjects.
Data Privacy: Implement measures to protect participant confidentiality and adhere to data protection regulations (e.g., GDPR, HIPAA).
6. Budget and Resource Allocation
Resource Planning: Allocate resources including time, budget, and personnel required for each phase of the research.
Contingency Planning: Anticipate and plan for unforeseen challenges or adjustments to the research plan.
7. Develop Research Instruments
Survey Design: Create well-structured surveys using tools like Google Forms to gather quantitative data.
Interview and Focus Group Guides: Prepare detailed scripts and discussion points for qualitative data collection.
8. Sampling Strategy
Sampling Design: Define the sampling frame, size, and method (e.g., random sampling, stratified sampling) to ensure representation of target demographics.
Participant Recruitment: Plan recruitment strategies to reach and engage the intended participant groups effectively.
9. Data Collection and Analysis Plan
Data Collection: Implement methods for data gathering, ensuring consistency and validity.
Analysis Techniques: Decide on analytical approaches (e.g., statistical
Research, Monitoring and Evaluation, in Public Healthaghedogodday
This is a presentation on the overview of the role of monitoring and evaluation in public health. It describes the various components and how a robust M&E system can possitively impact the results or effectiveness of a public health intervention.
NURSING MANAGEMENT OF PATIENT WITH EMPHYSEMA .PPTblessyjannu21
Prepared by Prof. BLESSY THOMAS, VICE PRINCIPAL, FNCON, SPN.
Emphysema is a disease condition of respiratory system.
Emphysema is an abnormal permanent enlargement of the air spaces distal to terminal bronchioles, accompanied by destruction of their walls and without obvious fibrosis.
Emphysema of lung is defined as hyper inflation of the lung ais spaces due to obstruction of non respiratory bronchioles as due to loss of elasticity of alveoli.
It is a type of chronic obstructive
pulmonary disease.
It is a progressive disease of lungs.
The facial nerve, also known as cranial nerve VII, is one of the 12 cranial nerves originating from the brain. It's a mixed nerve, meaning it contains both sensory and motor fibres, and it plays a crucial role in controlling various facial muscles, as well as conveying sensory information from the taste buds on the anterior two-thirds of the tongue.
At Malayali Kerala Spa Ajman, Full Service includes individualized care for every client. We specifically design each massage session for the individual needs of the client. Our therapists are always willing to adjust the treatments based on the client's instruction and feedback. This guarantees that every client receives the treatment they expect.
By offering a variety of massage services, our Ajman Spa Massage Center can tackle physical, mental, and emotional illnesses. In addition, efficient identification of specific health conditions and designing treatment plans accordingly can significantly enhance the quality of massaging.
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This particular slides consist of- what is hypotension,what are it's causes and it's effect on body, risk factors, symptoms,complications, diagnosis and role of physiotherapy in it.
This slide is very helpful for physiotherapy students and also for other medical and healthcare students.
Here is the summary of hypotension:
Hypotension, or low blood pressure, is when the pressure of blood circulating in the body is lower than normal or expected. It's only a problem if it negatively impacts the body and causes symptoms. Normal blood pressure is usually between 90/60 mmHg and 120/80 mmHg, but pressures below 90/60 are generally considered hypotensive.
nursing management of patient with Empyema pptblessyjannu21
prepared by Prof. BLESSY THOMAS, SPN
Empyema is a disease of respiratory system It is defines as the accumulation of thick, purulent fluid within the pleural space, often with fibrin development.
Empyema is also called pyothorax or purulent pleuritis.
It’s a condition in which pus gathers in the area between the lungs and the inner surface of the chest wall. This area is known as the pleural space.
Pus is a fluid that’s filled with immune cells, dead cells, and bacteria.
Pus in the pleural space can’t be coughed out. Instead, it needs to be drained by a needle or surgery.
Empyema usually develops after pneumonia, which is an infection of the lung tissue. it is mainly caused due in infectious micro-organisms. It can be treated with medications and other measures.
CHAPTER 1 SEMESTER V COMMUNICATION TECHNIQUES FOR CHILDREN.pdfSachin Sharma
Here are some key objectives of communication with children:
Build Trust and Security:
Establish a safe and supportive environment where children feel comfortable expressing themselves.
Encourage Expression:
Enable children to articulate their thoughts, feelings, and experiences.
Promote Emotional Understanding:
Help children identify and understand their own emotions and the emotions of others.
Enhance Listening Skills:
Develop children’s ability to listen attentively and respond appropriately.
Foster Positive Relationships:
Strengthen the bond between children and caregivers, peers, and other adults.
Support Learning and Development:
Aid cognitive and language development through engaging and meaningful conversations.
Teach Social Skills:
Encourage polite, respectful, and empathetic interactions with others.
Resolve Conflicts:
Provide tools and guidance for children to handle disagreements constructively.
Encourage Independence:
Support children in making decisions and solving problems on their own.
Provide Reassurance and Comfort:
Offer comfort and understanding during times of distress or uncertainty.
Reinforce Positive Behavior:
Acknowledge and encourage positive actions and behaviors.
Guide and Educate:
Offer clear instructions and explanations to help children understand expectations and learn new concepts.
By focusing on these objectives, communication with children can be both effective and nurturing, supporting their overall growth and well-being.
Digital Health in India_Health Informatics Trained Manpower _DrDevTaneja_15.0...DrDevTaneja1
Digital India will need a big trained army of Health Informatics educated & trained manpower in India.
Presently, generalist IT manpower does most of the work in the healthcare industry in India. Academic Health Informatics education is not readily available at school & health university level or IT education institutions in India.
We look into the evolution of health informatics and its applications in the healthcare industry.
HIMMS TIGER resources are available to assist Health Informatics education.
Indian Health universities, IT Education institutions, and the healthcare industry must proactively collaborate to start health informatics courses on a big scale. An advocacy push from various stakeholders is also needed for this goal.
Health informatics has huge employment potential and provides a big business opportunity for the healthcare industry. A big pool of trained health informatics manpower can lead to product & service innovations on a global scale in India.
R3 Stem Cell Therapy: A New Hope for Women with Ovarian FailureR3 Stem Cell
Discover the groundbreaking advancements in stem cell therapy by R3 Stem Cell, offering new hope for women with ovarian failure. This innovative treatment aims to restore ovarian function, improve fertility, and enhance overall well-being, revolutionizing reproductive health for women worldwide.
Solution manual for managerial accounting 18th edition by ray garrison eric n...rightmanforbloodline
Solution manual for managerial accounting 18th edition by ray garrison eric noreen and peter brewer_compressed
Solution manual for managerial accounting 18th edition by ray garrison eric noreen and peter brewer_compressed
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2. + =
have control
today
THE ENVIRONMENT YOUR GENES YOUR HEALTH
http://www.niehs.nih.gov/health/topics/science/gene-env/
The Diet- Gene Interaction
NATURE VS NURTURE
3. Genetic information serves as an additional tool
for assessment for dietetic professionals
Diet
Physical activity
Anthropometric
data
Biomedical data
Genetic data
4. Nutri +genetics = (the study of interaction
between nutrients & genes)
• AIMS TO UNRAVEL THE
INTERACTIONS BETWEEN NUTRIENTS
AND GENES.
• IT IS MORE SPECIFIC IN NATURE.
INDIVIDUALS VARY IN THEIR
NUTRIENT METABOLISM AND
RESPONSE TO DIET.
• IT HOLDS THE POTENTIAL TO PROVIDE
BETTER NUTRITIONAL ADVICE TO
PREVENT OR TO OVERCOME DISEASE
RISKS.
5. The Personalised Nutrition Approach
In this personalised nutrition approach:
• We analyse genetic variations found in human DNA called single nucleotide polymorphisms
(SNPs). Almost all of DNA are the same (99.9%) and 0.1% is different and that is due to these
SNPs.
• These SNPs are common genetic variations, some of these variations have no effect while
others are known to be very important for health status and disease risk.
• The variations can affect gene function, altering the way nutrients are metabolised. This can
have a detrimental effect on the body, influencing human phenotype – the observable,
physical characteristic of a person.
6. Personalised nutrition approach
One size fit’s all approach is not effective
ADIPOQ gene:
AA genotype carriers do not benefit by
consuming MUFA rich foods and they are at
increased risk of obesity, when they consume
more than ( >13% of the total calories) from
MUFA.
CC genotype carriers benefit by consuming
MUFA rich foods.
Based on the type of genetic variation, dietary
recommendations are designed.
7. A vitamin deficiency can be caused by
either insufficient intake, or by the body’s
ability to metabolise it because of a
genetic variation – via the action of an
SNP.
For example, vitamin B12 deficiency is
highly prevalent among Indians. By
knowing their genetic make up, more
specific recommendations can be given.
Personalised nutrition approach:
Helps to get thorough understanding of the gene-diet
interactions.
8. Personalised Nutrition Approach:
Is based on genetic makeup and not on generalised population-based data
North Indians are more lactose tolerant
than western & South Indians.
Differences are seen even within same
ethnicity/ population.
9. “One Size fit all” approach is helpful but not
effective to combat chronic lifestyle diseases
Human health is the result of constant interaction between genes and environmental factors which are our diets and lifestyle. We are 97 to 99% genetically identical and the fundamental processes of food metabolism in every human body are the same. This is why eating healthy and staying active are beneficial to everyone. However, the 1 to 3% genome difference among us makes us respond differently to different types of food. This is why personalized diets are necessary. One size doesn’t fit all is the concept behind personalised nutrition. A mismatch between genes and diet would inevitably lead to detrimental effects on our health. These effects over a period of time manifest as a chronic disease(gbhealthwatch.com).
How many of you here are diabetic/ hypertensive/ high cholesterol or a cardiac ailment?
Let’s have a look at the global and also Indian scenario on the NCD’s which are nothing but the non communicable diseases which are nothing but lifestyle related diseases to put in simpler terms.