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Introduction to
NEUROLOGY
Dr. WALID REDA ASHOUR
ASSISST. PROFESSOR OF
NEUROLOGY
INTRODUCTION
WHAT IS NEUROLOGY?
Neurology is the branch of medicine that
deals with diseases of the nervous system.
MAJOR DIVISIONS
NERVOUS
SYSTEM
CENTRAL
NERVOUS
SYSTEM
PERIPHERAL
NERVOUS
SYSTEM
CENTRAL NERVOUS SYSTEM
1. Cerebrum
2. Brain stem
3. Cerebellum
CNS
Intracranial
part
Spinal
part
1- Spinal cord
2- Cauda equina
I- INTRACRANIAL PART
1- CEREBRUM
Two (2) cerebral hemispheres.
Connected to:
1. Each other by CORPUS CALLOSUM.
2. Brain stem by CEREBRAL PEDUNCLES.
- Outer gray matter (cerebral cortex) contains certain
areas with specific functions.
- Inner white matter composed of nerve fibers
conducting impulses TO & FROM cerebral cortex
EACH cerebral hemisphere divided into :
FOUR ( 4 ) LOBES:
1. Frontal
2. Parietal
3. Temporal
4. Occipital
2- Brain stem
Formed of :
1- Midbrain
2- Pons
3- Medulla
Connected to:
1. Cerebral hemisphere
by cerebral peduncles
2. Cerbellum by cerebellar
peduncles
BRAIN STEM contains motor nuclei of cranial
nerves:
• 3 & 4 in MIDBRAIN
• 5, 6 &7 in PONS
• 9, 10, 11 & 12 in MEDULLA
N.B. 1, 2 & 8
are sensory nerves have no
motor nuclei
NAMES OF CRANIAL NERVES
• 1 Olfactory
• 2 Optic
• 3 Oculomotor
• 4 Trochlear
• 5 Trigeminal
• 6 Abducent
• 7 Facial
• 8 Vestibulocochlear
• 9 Glossopharyngeal
• 10 Vagus
• 11 Accessory
• 12 Hypoglossal
CLASSIFICATION OF CRANIAL NERVES
• SENSORY : contain only sensory fibers
1- Olfactory
2- Optic
8- Vestibulocochlear
• MOTOR : contain only motor fibers
3- Oculomotor
4- Trochlear
6- Abducent
11- Accessory
12- Hypoglossal
• MIXED : contain both sensory and motor fibers
5- Trigeminal
7- Facial
9- Glossopharyngeal
10- Vagus
Sensory cranial nerves
N. Name Function Assessment
1 Olfactory Smell Examination of
smell
2 Optic Vision Acuity, field &
fundus
8 Vestibular
part
Equilibrium Caloric and
rotational chair
Cochlear
part
Hearing Watch test,
Weber test
Motor cranial nerves
N. Name Function Assessment
3 Oculomotor Motor to superior, inferior and
medial recti; inferior oblique
& levator palpebrae superioris
Ptosis, pupil, eye
movements &
squint
Parasympathetic to sphincter
papillae and ciliary muscle
4 Trochlear Motor to superior oblique Look to opposite
shoulder
6 Abducent Motor to lateral rectus Lateral eye
movement
11 Accessory Motor to sternocleidomastoid
and trapezius
Elevaton of
shoulders and
neck rotation
12 Hypoglossal Motor to muscles of tongue Tongue
movements
Mixed cranial nerves
N. Name Function Assessment
5 Trigeminal Muscles of
mastication &
sensations of face
Face sensations &
power of muscles of
mastication
7 Facial Muscles of facial
expression & taste
sensation in ant. 1/3
of tongue
Muscles of facial
expression & taste
sensation in ant. 1/3 of
tongue
10 Vagus Sensation and
movements of
Larynx, pharynx,
thoracic and
abdominal organs
Palatal and pharyngeal
reflexes & movements of
uvula
9 Glossopharyngeal Taste in post 2/3 of
tongue & gen.
sensation
Taste & general
sensation and
pharyngeal reflex
3- CEREBELLUM
• Behind the brain stem
• Formed of : * Medline vermis
* Two cerebellar
hemispheres
• Composed of :
Outer grey matter and inner
white matter
MB
Pons C
MO
n Superior peduncle connects cerebellum with MIDBRAIN.
n Middle peduncle connects cerebellum with PONS.
n Inferior peduncle connects cerebellum with MEDULLA
OBLONGATA
CEREBELLAR PEDUNCLES
Left
Hemisphere
right
hemisphere
CEREBELLAR HEMISPHERES AND VERMIS
Cerebellar Hemispheres are the two bilateral structures.
Vermis is the unpaired midline structure between
the two hemispheres.
VERMIS
II- SPINAL PART
1- SPINAL CORD
• Inside spinal canal
• End at lower border of L1 vertebra.
• Its lowermost 3 segments S3,4,5 = Conus.
• The above 4 segments L4,5 & S1,2 = Epiconus.
• Inner grey matter (cells) surrounded by
white matter.
SPINAL CORD
SPINAL CORD TRACTS
• White matter contains ascending and
descending nerve fibers (TRACTS):
1- ASCENDING
• Lateral & Ventral spinothalamic.
• Gracile & Cuneate.
• Spinocerebellar.
• Lissauer’s.
2- DESCENDING
• Corticospinal (pyramidal).
• Reticulospinal, vestibulospinal, tectospinal, rubrospinal &
olivospinal
2- CAUDA EQUINA
• Collection of LUMBOSACRAL ROOTS which
fills the lower part of the spinal canal below
L1 vertebra.
THE MOTOR SYSTEM
Motor pathway
UPPER MOTOR NEURON
(pyramidal system)
* Originates in motor area 4 & premotor area 6
* Terminates at the anterior horn cells (AHCs)
of the different levels of the spinal cord.
* It supplies the opposite side of the body.
LOWER MOTOR NEURON
• Formed of AHCs & Peripheral motor nerves
(which transmit the motor impulses to the
voluntry muscles).
EXTRA PYRAMIDAL SYSTEM
• Originates from centers at various levels of CNS
mainly the BASAL GANGLIA.
• It controls the opposite side of the body.
CEREBELLAR SYSTEM
• Composed of Neo, Archi & Paleo- cerebellum.
• It co-ordinates the movements of the same side of
the body.
UMNL LMNL
Tone Increased, with
‘clasp knife’ quality
Decreased
Clonus Present Absent
Fasciculations Absent Present
Muscle Wasting Absent, but disuse
atrophy eventually
results
Present (within 2-3
weeks)
Tendon Reflexes Increased. Extensor
plantar reflexes.
Decreased or
absent. Flexor
plantar reflexes.
Distribution Whole limbs, with
more weakness in
the upper limb
extensors and lower
limb flexors
Specific muscle
groups affected (e.g.
in the distribution of
a spinal segment, or
just the proximal
muscles, etc.)
Thank you

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Introduction to Neurology

  • 1. Introduction to NEUROLOGY Dr. WALID REDA ASHOUR ASSISST. PROFESSOR OF NEUROLOGY
  • 2.
  • 4. WHAT IS NEUROLOGY? Neurology is the branch of medicine that deals with diseases of the nervous system.
  • 7. 1. Cerebrum 2. Brain stem 3. Cerebellum CNS Intracranial part Spinal part 1- Spinal cord 2- Cauda equina
  • 9. 1- CEREBRUM Two (2) cerebral hemispheres. Connected to: 1. Each other by CORPUS CALLOSUM. 2. Brain stem by CEREBRAL PEDUNCLES. - Outer gray matter (cerebral cortex) contains certain areas with specific functions. - Inner white matter composed of nerve fibers conducting impulses TO & FROM cerebral cortex
  • 10. EACH cerebral hemisphere divided into : FOUR ( 4 ) LOBES: 1. Frontal 2. Parietal 3. Temporal 4. Occipital
  • 11. 2- Brain stem Formed of : 1- Midbrain 2- Pons 3- Medulla Connected to: 1. Cerebral hemisphere by cerebral peduncles 2. Cerbellum by cerebellar peduncles
  • 12. BRAIN STEM contains motor nuclei of cranial nerves: • 3 & 4 in MIDBRAIN • 5, 6 &7 in PONS • 9, 10, 11 & 12 in MEDULLA N.B. 1, 2 & 8 are sensory nerves have no motor nuclei
  • 13. NAMES OF CRANIAL NERVES • 1 Olfactory • 2 Optic • 3 Oculomotor • 4 Trochlear • 5 Trigeminal • 6 Abducent • 7 Facial • 8 Vestibulocochlear • 9 Glossopharyngeal • 10 Vagus • 11 Accessory • 12 Hypoglossal
  • 14. CLASSIFICATION OF CRANIAL NERVES • SENSORY : contain only sensory fibers 1- Olfactory 2- Optic 8- Vestibulocochlear • MOTOR : contain only motor fibers 3- Oculomotor 4- Trochlear 6- Abducent 11- Accessory 12- Hypoglossal • MIXED : contain both sensory and motor fibers 5- Trigeminal 7- Facial 9- Glossopharyngeal 10- Vagus
  • 15. Sensory cranial nerves N. Name Function Assessment 1 Olfactory Smell Examination of smell 2 Optic Vision Acuity, field & fundus 8 Vestibular part Equilibrium Caloric and rotational chair Cochlear part Hearing Watch test, Weber test
  • 16. Motor cranial nerves N. Name Function Assessment 3 Oculomotor Motor to superior, inferior and medial recti; inferior oblique & levator palpebrae superioris Ptosis, pupil, eye movements & squint Parasympathetic to sphincter papillae and ciliary muscle 4 Trochlear Motor to superior oblique Look to opposite shoulder 6 Abducent Motor to lateral rectus Lateral eye movement 11 Accessory Motor to sternocleidomastoid and trapezius Elevaton of shoulders and neck rotation 12 Hypoglossal Motor to muscles of tongue Tongue movements
  • 17. Mixed cranial nerves N. Name Function Assessment 5 Trigeminal Muscles of mastication & sensations of face Face sensations & power of muscles of mastication 7 Facial Muscles of facial expression & taste sensation in ant. 1/3 of tongue Muscles of facial expression & taste sensation in ant. 1/3 of tongue 10 Vagus Sensation and movements of Larynx, pharynx, thoracic and abdominal organs Palatal and pharyngeal reflexes & movements of uvula 9 Glossopharyngeal Taste in post 2/3 of tongue & gen. sensation Taste & general sensation and pharyngeal reflex
  • 18. 3- CEREBELLUM • Behind the brain stem • Formed of : * Medline vermis * Two cerebellar hemispheres • Composed of : Outer grey matter and inner white matter
  • 19. MB Pons C MO n Superior peduncle connects cerebellum with MIDBRAIN. n Middle peduncle connects cerebellum with PONS. n Inferior peduncle connects cerebellum with MEDULLA OBLONGATA CEREBELLAR PEDUNCLES
  • 20. Left Hemisphere right hemisphere CEREBELLAR HEMISPHERES AND VERMIS Cerebellar Hemispheres are the two bilateral structures. Vermis is the unpaired midline structure between the two hemispheres. VERMIS
  • 22. 1- SPINAL CORD • Inside spinal canal • End at lower border of L1 vertebra. • Its lowermost 3 segments S3,4,5 = Conus. • The above 4 segments L4,5 & S1,2 = Epiconus. • Inner grey matter (cells) surrounded by white matter.
  • 24. SPINAL CORD TRACTS • White matter contains ascending and descending nerve fibers (TRACTS): 1- ASCENDING • Lateral & Ventral spinothalamic. • Gracile & Cuneate. • Spinocerebellar. • Lissauer’s. 2- DESCENDING • Corticospinal (pyramidal). • Reticulospinal, vestibulospinal, tectospinal, rubrospinal & olivospinal
  • 25. 2- CAUDA EQUINA • Collection of LUMBOSACRAL ROOTS which fills the lower part of the spinal canal below L1 vertebra.
  • 28. UPPER MOTOR NEURON (pyramidal system) * Originates in motor area 4 & premotor area 6 * Terminates at the anterior horn cells (AHCs) of the different levels of the spinal cord. * It supplies the opposite side of the body.
  • 29. LOWER MOTOR NEURON • Formed of AHCs & Peripheral motor nerves (which transmit the motor impulses to the voluntry muscles).
  • 30. EXTRA PYRAMIDAL SYSTEM • Originates from centers at various levels of CNS mainly the BASAL GANGLIA. • It controls the opposite side of the body. CEREBELLAR SYSTEM • Composed of Neo, Archi & Paleo- cerebellum. • It co-ordinates the movements of the same side of the body.
  • 31. UMNL LMNL Tone Increased, with ‘clasp knife’ quality Decreased Clonus Present Absent Fasciculations Absent Present Muscle Wasting Absent, but disuse atrophy eventually results Present (within 2-3 weeks) Tendon Reflexes Increased. Extensor plantar reflexes. Decreased or absent. Flexor plantar reflexes. Distribution Whole limbs, with more weakness in the upper limb extensors and lower limb flexors Specific muscle groups affected (e.g. in the distribution of a spinal segment, or just the proximal muscles, etc.)
  • 32.