Spinal Tumors: approach and managementAmit Agrawal
The spinal cord consists of
Central canal surrounded by an H-shaped gray matter region containing neurons
Outer myelinated nerve tracts, termed white matter, surround the central gray matter
Central canal is lined with ependymal cells
Astrocytes support gray matter neurons and white matter axons
Spinal Tumors: approach and managementAmit Agrawal
The spinal cord consists of
Central canal surrounded by an H-shaped gray matter region containing neurons
Outer myelinated nerve tracts, termed white matter, surround the central gray matter
Central canal is lined with ependymal cells
Astrocytes support gray matter neurons and white matter axons
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Contents
Knee Joint anatomy with Diagrams
Anatomical Components of Knee
Anatomy of Patella
Innervations of the Knee
Knee Movements
Osteoarthritis in the Knee
Management of Disorders in Knee joint
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
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Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
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is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
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Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
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Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
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O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
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Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
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These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
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5. Describe the cough and sneeze reflexes
Study Resources:
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2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
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The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
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2. Reasons for pelvic injuries:
Road accident
Catatrauma
Lethality at
fractures of the pelvis
is
5-35.8%
(John T., 2005)
3. Bone ring formed by two iliac bones, sacrum and coccyx.
The main ligaments that bind bone structures:
sacroiliac (anterior, posterior and interosseous),
sacroiliac, sacroiliac, sacrospinous
4. Classification of pelvic injuries by AO / ASI
"Stability - instability"
continuity - the continuity of the pelvic ring and the state of the ligaments of the
sacroiliac joints.
Type A includes stable injuries without violating the continuity of the pelvic ring
Type B - rotational-unstable injuries.With a violation of the continuity of the
anterior or posterior pelvic ring.
To type C (the most difficult) - vertically - unstable damages.With a violation of
the continuity of the anterior and posterior pelvic ring.
5.
6. Type A
stable
Marginal fractures of the iliac
wing, upper or lower spine,
the edge of the sciatic
hump, the edge of the
sacrum and coccyx
7.
8. Type В
Rotationally unstable
Ruptures of the pubic
symphysis or fractures
of the anterior pelvis
of the "open book"
type + rupture of the
ventral sacroiliac
ligaments,
damage to both
sacroiliac joints.
9.
10.
11.
12. Type C Vertically unstable
A combination of
vertically rotational
unstable injury on one
side of the pelvis and
rotational unstable injury
on the other, bilateral
vertically rotational
unstable pelvic injuries.
17. Traumatic shock
30% -in unstable pelvic fractures
100% - with pelvic fractures + fractures of large
segments of the musculoskeletal system + damage
to internal organs
The patient's life depends on the
duration and scope of treatment at all
stages of medical care
Mortality is 73.27% in the first 3 days.
.
18. Stage Systolic
BP
Volume of
blood loss
Algover’s
Index
HR/SPB
Consciousness
I 90 До1 0,8-1 +
II 70-90 1 – 1,5 1,1-1,5 +
III 50-70 1,5-2 1,6 + - (sopor)
IV terminal -
Traumatic shock
19. Type A No shock, little blood loss
Factors in the development of
shock are:
concomitant multiple,
combined and combined
injuries, blood loss,
pain factor;
late and inadequate first aid.
Type B, C (about 31% traumatic shock)
20. The adequacy of anti-shock treatment
depends on:
from the timeliness of treatment (at the
scene, transportation)
from the speed of hospitalization - during
the first ("golden") hour from the moment
of injury.
21. Treatment of traumatic shock:
1.Stop bleeding
2. Ensuring airway patency (airway, laryngeal mask)
3. Artificial lung ventilation
4. Catheterization of peripheral veins
5. Restoration of cardiac activity (hydrocortisone,
epinephrine, norepinephrine).
6. Anesthesia
7. Restoration of BCC (transfusion of warm solutions),
8. Warming up the victim
9. Immobilization of the cervical spine.
22. Treatment of traumatic shock:
10. Immobilization of both halves of the pelvis by corset
fixation (hammock), frame-pneumatic orthosis
11. The correct position of the patient - on a semi-soft
surface of the burden in a semi-sitting position with
moderately bent in the hip joints of the lower
extremities, with fixation of the latter and the torso.
12. Pelvic anesthesia according to Selivanov-
Shkolnikov.
24. In the admission department (surgeon, traumatologist, neurosurgeon, resuscitator, urologist and
others).
• In the anti-shock ward of the department the resuscitator provides:
• monitoring of vital functions, adequacy of external respiration
• (if necessary, conducts tracheal intubation, mechanical ventilation)
• ECG
• the next laboratory assistant takes a general blood test to determine hematocrit and sugar.
• correction of infusion therapy - intravenous injection depending on the degree of shock
• 500 ml of warm physiological saline, 500 ml of solution, hydroxyethyl starch (voluven,
KhNPP-sterile, gecodesis) or 250 ml of hyperHNPP are introduced,
• 4 ml of dicynon, 10 ml of calcium chloride
• 250 mg of hydrocortisone.
• catheterization of the bladder is performed.
25. Examination: multislice computed tomography of the pelvis
and other damaged areas of the body (MS CT)
or radiography of the pelvis and damaged segments of the
body, chest.
Ultrasound of the parenchymal organs of the abdominal
cavity and retroperitoneal space.
In the intensive care unit for a full range of
intensive care.
NB. MRI and CT of the brain are performed
only after stabilization of the general condition
of the patient.
Type A (stable) Type B/C (unstable)
In traumatological department
26. After resuscitation:
First turn:
urgent medical and diagnostic surgical interventions:
thoracentesis, laparocentesis. In cases of intra-abdominal
bleeding, laparotomy and hemostasis are performed.
Unstable pelvic injuries of one-moment repositioning of the
pelvic halves and fixation of the pelvis by means of a Hanz frame
or external fixation devices (Extrafocal apparatus).
27. At the second stage of treatment after correction of the
general condition of the patient of operation:
osteosynthesis of bones of large segments, mainly by
external fixation devices,
blocking intramedullary rods (nailing)
to ensure the conditions of adequate bed rest, prevention
of hypodynamic disorders due to the forced position of
the patient, which is important for the prevention of
complications.
28. At the third stage (the average term of the third
stage is 12-14 days) the final traumatological
correction of the pelvic fracture is performed by
open repositioning and internal fixation with
shaped plates and screws.
31. Hanging in a hammock
Options for conservative treatment
of unstable pelvic fractures:
32. Beller tires, Volkovich position, skeletal traction
Options for conservative treatment of
unstable pelvic fractures:
33. Fractures of the acetabulum of the pelvis.
Classification:
fractures of the posterior edge or roof of the
acetabulum without dislocation
fractures of the posterior edge or roof of the
acetabulum with dislocation of the femur;
fracture of the bottom of the acetabulum with
central dislocation of the femur;
horizontal fracture of the iliac bone at the level of
the acetabulum.
41. There are two support complexes in the spine - anterior and
posterior.
42. Stable and unstable
Unstable - damage to the posterior fixation
complex (arches, arcuate joints, spinous and
transverse processes) and ligaments.
There is a tendency to displace the vertebrae
with the threat of compression of the
neurovascular formations of the spinal canal.
44. Damage by the nature of the violation of the structures
of the spine
1. Damage to the communication device
2. Fractures of vertebral bodies
3. Damage to the intervertebral discs with rupture of
the fibrous ring and displacement of the pulpal
nucleus.
4. Fractures of the posterior half-ring of the vertebrae
(arches, joints, transverse or spinous processes).
5. Subluxations, dislocations and fractures-dislocations
of vertebrae
6.Traumatic spondylolisthesis.
47. X-ray examination of the cervical spine is performed in
two projections: anterior-posterior and lateral
Dislocations in the atlanto-occipital joint.
49. Conservative treatment of stable injuries
At unstable fractures in cervical department of a backbone and in case of
deformation of the channel of a backbone operative treatment
anterior corporodesis - open reposition from the anterior access with fixation of
the damaged segment of the spine by bone autografts.
50. Trauma to the thoracic and lumbar spine
the main mechanism of action of forces on the
spine -
compression (A),
stretching (B)
rotational - axial torsion (C).
The vertebrae are most often damaged
in the most motor part of the spine
- from X thoracic to III lumbar.
51. The most informative
computed tomography,
MRI
which make it possible to obtain accurate information
about the condition of all structures of the examined
vertebra, spinal canal and disc.
53. Treatment of stable fractures of the thoracic
spine
Functional method - on the recliner
54. Functional method of treatment of compression
fractures of the vertebrae, proposed by Gorynevskaya
and Dreving (1932).
In the first period (2 - 10th day) reach the maximum reclination of the spine and
prescribe therapeutic gymnastics of a general hygienic nature and exercises
for the upper extremities and feet.
The second period begins on the 10th and lasts until the 25th day. In addition to general
hygienic exercises in this period appoint active movements of the upper extremities with a
gradual connection to the active movements of the lower extremities, back muscles by lifting
the pelvis, torso, exercises in the supine position. Assign massage of the upper and lower
extremities.
The third period is the 25th-60th day after the injury. In addition to the exercises of the second
period, intensive exercises are prescribed to strengthen the muscles of the back and
abdomen. Under no circumstances should torso flexion exercises be prescribed. Patients
raise the torso and pelvis, resting on elbows and knees, crawl on the bed. Prescribe back
muscle massage.
The fourth period covers 60-90 days after injury. The victims continue to perform the exercises
of the third period, as well as learn to get out of bed, then - to walk, maintaining a posture, and
gradually increase the time spent on their feet, join an active social life.
55. Complicated closed spinal injuries:
• Concussion of the spinal cord
• Spinal cord injury
• Compression of the spinal cord
56. Emergency medical care:
Careful release of the victim from under blockages, cars, etc.
Immobilization of the cervical spine with a rigid splint, orthosis
(Kendrick) - complete, reliable - immobilization on the principle of
"only 1 time".
Resumption of respiration (if necessary, carefully - air duct).
Methylprednisolone 30 mg / kg is administered intravenously for
the first 8 hours, then 15 mg / kg every 6 hours, then 5 mg / kg
every 48 hours for 48 hours.
Correction of bradycardia, low blood pressure: atropine sulfate,
dopamine, rheopolyglucin, polyglucin, hypertonic (3-7%) NaCl
solution - BCC recovery.
57. Emergency medical care:
6. Simultaneous transfer of the patient - on the principle of
"head-neck-chest - a single whole" on a semi-rigid stretcher with
a roller placed under the knees and fixation of the victim.
7. Hospitalization in a horizontal position.
8. Furosemidum 40mg. intravenously or intravenously, piracetam
5.0 intravenously, cerebrolysin 15-30 ml intravenously, vitamin E.
5 ml intravenously, diphenine 500 mg intravenously, analgesics,
sedatives
9. Return of the patient every 2 hours.
10. Catheterization of the bladder
11. Ventilation through a mask.
12. Hospitalization in the neurosurgical department.