The document summarizes key aspects of spinal anatomy and injuries. It describes the characteristics of the cervical, thoracic, lumbar, and sacral regions. Common mechanisms of spinal injury include falls, motor vehicle crashes, and blunt or penetrating trauma. Signs suggestive of spinal injury include neck pain or tenderness, numbness, weakness, and loss of bowel or bladder control. Evaluation involves physical exam including motor and sensory function tests. Imaging with x-rays, CT, and MRI is used for diagnosis. Management principles focus on immobilization, resuscitation, corticosteroid administration in some cases, and surgery for unstable injuries with neurological deficits.
Cervical Hybrid Arthroplasty by Pablo Pazmino MDPablo Pazmino
This video explains Cervical Arthroplasty in combination with a fusion. When people have more than one cervical disc which has degenerated or which has sustained a traumatic rupture they may need a procedure to address both levels. These herniations may begin to affect the surrounding nerves and/or spinal cord. This video highlights the history, epidemiology, and treatment options both conservative and surgical. If you or someone you know needs to be seen in regards to Cervical Herniations/ Radiculopathy at multiple levels feel free to look us up online www.beverlyspine.com or call toll free 1-8SPINECAL-1
Neck Pain and Arm Pain : Cervical Radiculopathy by Pablo Pazmino MDPablo Pazmino
This video explains Cervical Radiculopathy and Cervical Herniations. When herniations begins to affect the nerves and spinal cord this is called Cervical Radiculopathy. This video highlights the history, epidemiology, and treatment options both conservative and surgical. If you or someone you know needs to be seen in regards to Cervical Herniation/Radiculopathy feel free to look us up online www.beverlyspine.com or www.santamonicaspine.com OR call toll free 1-8SPINECAL-1
The dimensions of healthcare quality refer to various attributes or aspects that define the standard of healthcare services. These dimensions are used to evaluate, measure, and improve the quality of care provided to patients. A comprehensive understanding of these dimensions ensures that healthcare systems can address various aspects of patient care effectively and holistically. Dimensions of Healthcare Quality and Performance of care include the following; Appropriateness, Availability, Competence, Continuity, Effectiveness, Efficiency, Efficacy, Prevention, Respect and Care, Safety as well as Timeliness.
Antibiotic Stewardship by Anushri Srivastava.pptxAnushriSrivastav
Stewardship is the act of taking good care of something.
Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms.
WHO launched the Global Antimicrobial Resistance and Use Surveillance System (GLASS) in 2015 to fill knowledge gaps and inform strategies at all levels.
ACCORDING TO apic.org,
Antimicrobial stewardship is a coordinated program that promotes the appropriate use of antimicrobials (including antibiotics), improves patient outcomes, reduces microbial resistance, and decreases the spread of infections caused by multidrug-resistant organisms.
ACCORDING TO pewtrusts.org,
Antibiotic stewardship refers to efforts in doctors’ offices, hospitals, long term care facilities, and other health care settings to ensure that antibiotics are used only when necessary and appropriate
According to WHO,
Antimicrobial stewardship is a systematic approach to educate and support health care professionals to follow evidence-based guidelines for prescribing and administering antimicrobials
In 1996, John McGowan and Dale Gerding first applied the term antimicrobial stewardship, where they suggested a causal association between antimicrobial agent use and resistance. They also focused on the urgency of large-scale controlled trials of antimicrobial-use regulation employing sophisticated epidemiologic methods, molecular typing, and precise resistance mechanism analysis.
Antimicrobial Stewardship(AMS) refers to the optimal selection, dosing, and duration of antimicrobial treatment resulting in the best clinical outcome with minimal side effects to the patients and minimal impact on subsequent resistance.
According to the 2019 report, in the US, more than 2.8 million antibiotic-resistant infections occur each year, and more than 35000 people die. In addition to this, it also mentioned that 223,900 cases of Clostridoides difficile occurred in 2017, of which 12800 people died. The report did not include viruses or parasites
VISION
Being proactive
Supporting optimal animal and human health
Exploring ways to reduce overall use of antimicrobials
Using the drugs that prevent and treat disease by killing microscopic organisms in a responsible way
GOAL
to prevent the generation and spread of antimicrobial resistance (AMR). Doing so will preserve the effectiveness of these drugs in animals and humans for years to come.
being to preserve human and animal health and the effectiveness of antimicrobial medications.
to implement a multidisciplinary approach in assembling a stewardship team to include an infectious disease physician, a clinical pharmacist with infectious diseases training, infection preventionist, and a close collaboration with the staff in the clinical microbiology laboratory
to prevent antimicrobial overuse, misuse and abuse.
to minimize the developme
Global launch of the Healthy Ageing and Prevention Index 2nd wave – alongside...ILC- UK
The Healthy Ageing and Prevention Index is an online tool created by ILC that ranks countries on six metrics including, life span, health span, work span, income, environmental performance, and happiness. The Index helps us understand how well countries have adapted to longevity and inform decision makers on what must be done to maximise the economic benefits that comes with living well for longer.
Alongside the 77th World Health Assembly in Geneva on 28 May 2024, we launched the second version of our Index, allowing us to track progress and give new insights into what needs to be done to keep populations healthier for longer.
The speakers included:
Professor Orazio Schillaci, Minister of Health, Italy
Dr Hans Groth, Chairman of the Board, World Demographic & Ageing Forum
Professor Ilona Kickbusch, Founder and Chair, Global Health Centre, Geneva Graduate Institute and co-chair, World Health Summit Council
Dr Natasha Azzopardi Muscat, Director, Country Health Policies and Systems Division, World Health Organisation EURO
Dr Marta Lomazzi, Executive Manager, World Federation of Public Health Associations
Dr Shyam Bishen, Head, Centre for Health and Healthcare and Member of the Executive Committee, World Economic Forum
Dr Karin Tegmark Wisell, Director General, Public Health Agency of Sweden
CRISPR-Cas9, a revolutionary gene-editing tool, holds immense potential to reshape medicine, agriculture, and our understanding of life. But like any powerful tool, it comes with ethical considerations.
Unveiling CRISPR: This naturally occurring bacterial defense system (crRNA & Cas9 protein) fights viruses. Scientists repurposed it for precise gene editing (correction, deletion, insertion) by targeting specific DNA sequences.
The Promise: CRISPR offers exciting possibilities:
Gene Therapy: Correcting genetic diseases like cystic fibrosis.
Agriculture: Engineering crops resistant to pests and harsh environments.
Research: Studying gene function to unlock new knowledge.
The Peril: Ethical concerns demand attention:
Off-target Effects: Unintended DNA edits can have unforeseen consequences.
Eugenics: Misusing CRISPR for designer babies raises social and ethical questions.
Equity: High costs could limit access to this potentially life-saving technology.
The Path Forward: Responsible development is crucial:
International Collaboration: Clear guidelines are needed for research and human trials.
Public Education: Open discussions ensure informed decisions about CRISPR.
Prioritize Safety and Ethics: Safety and ethical principles must be paramount.
CRISPR offers a powerful tool for a better future, but responsible development and addressing ethical concerns are essential. By prioritizing safety, fostering open dialogue, and ensuring equitable access, we can harness CRISPR's power for the benefit of all. (2998 characters)
CHAPTER 1 SEMESTER V - ROLE OF PEADIATRIC NURSE.pdfSachin Sharma
Pediatric nurses play a vital role in the health and well-being of children. Their responsibilities are wide-ranging, and their objectives can be categorized into several key areas:
1. Direct Patient Care:
Objective: Provide comprehensive and compassionate care to infants, children, and adolescents in various healthcare settings (hospitals, clinics, etc.).
This includes tasks like:
Monitoring vital signs and physical condition.
Administering medications and treatments.
Performing procedures as directed by doctors.
Assisting with daily living activities (bathing, feeding).
Providing emotional support and pain management.
2. Health Promotion and Education:
Objective: Promote healthy behaviors and educate children, families, and communities about preventive healthcare.
This includes tasks like:
Administering vaccinations.
Providing education on nutrition, hygiene, and development.
Offering breastfeeding and childbirth support.
Counseling families on safety and injury prevention.
3. Collaboration and Advocacy:
Objective: Collaborate effectively with doctors, social workers, therapists, and other healthcare professionals to ensure coordinated care for children.
Objective: Advocate for the rights and best interests of their patients, especially when children cannot speak for themselves.
This includes tasks like:
Communicating effectively with healthcare teams.
Identifying and addressing potential risks to child welfare.
Educating families about their child's condition and treatment options.
4. Professional Development and Research:
Objective: Stay up-to-date on the latest advancements in pediatric healthcare through continuing education and research.
Objective: Contribute to improving the quality of care for children by participating in research initiatives.
This includes tasks like:
Attending workshops and conferences on pediatric nursing.
Participating in clinical trials related to child health.
Implementing evidence-based practices into their daily routines.
By fulfilling these objectives, pediatric nurses play a crucial role in ensuring the optimal health and well-being of children throughout all stages of their development.
Deep Leg Vein Thrombosis (DVT): Meaning, Causes, Symptoms, Treatment, and Mor...The Lifesciences Magazine
Deep Leg Vein Thrombosis occurs when a blood clot forms in one or more of the deep veins in the legs. These clots can impede blood flow, leading to severe complications.
Telehealth Psychology Building Trust with Clients.pptxThe Harvest Clinic
Telehealth psychology is a digital approach that offers psychological services and mental health care to clients remotely, using technologies like video conferencing, phone calls, text messaging, and mobile apps for communication.
3. Cervical
Small vertebral bodies (lesser
weight bearing)
Extensive joint surfaces
allows greater ROM (rot, flex,
ext)
Thoracic
Rib bearing vertebrae
Designed to remain stiff
(minimal flex, ext)
Lumbar
Weight-bearing vertebrae,
houses cauda equine. (min
rot)
Sacral
Transmits weight of body to
the pelvis.
(no motion)
Anatomy
4. Anatomy
Spinal nerve roots pass out
intervertebral foramen
C1-7 exit above
C8-L5 exit below
Spinal nerve: ventral (motor), dorsal
(sensor)
Sensoric cells in dorsal
Motoric cells in Ventral horn
Cauda equina
formed by L & S nerve in the spinal canal
before exiting
5. Mechanism of injury
Direct injury
Penetrating injuries to the spine, particularly from
firearms and knives
Indirect injury
Most common cause of significant spinal damage
Fall from a height spinal column collapses in
vertical axis
Forces: axial compression, flexion, lateral
compression, flexion-rotation, shear, flexion-
distraction and extension
Eisenstein S, Marsy WE. Injuries of the spine. Apley’s System of Orthopaedics and Fractures. 9th edition. 2010
6. •Motorcycle crashes
•Falls
• Hangings
• Blunt trauma
• Penetrating trauma to the head, neck
• Gunshot wounds
• Any unresponsive trauma patient
Suspicious: A Spine Injury?
7. Stable vs
Unstable
Treat as unstable until proven otherwise
Stable injuries
Vertebral components will not be displaced by normal
movements.
Little risk of neural damage
Unstable injuries
There is a significant risk of displacement and consequent
damage – or further damage – to the neural tissues
Eisenstein S, et al. Injuries of the spine. Apley’s System of Orthopaedics and Fractures. 9th edition. 2010
8. Clinical Evaluation
Injuries of the vertebral column tend to cluster
at the junctional areas:
Craniocervical junction (occiput to C2)
Cervicothoracic junction (C7-T1)
Thoracolumbar junction (T11-L2).
Eisenstein S, Marsy WE. Injuries of the spine. Apley’s System of Orthopaedics and Fractures. 9th edition. 2010
9. Diagnosis
KEY POINTS:
Every patient with a blunt injury above the clavicle, a head
injury or loss of consciousness should be considered to have a
cervical spine injury until proven otherwise
Every patient who is involved in a fall from a height or a high-
speed deceleration accident should similarly be considered to
have a thoracolumbar injury
Consider the presence of a vertebral column injury in all
patients with multiple injuries
Lesser injuries also should arouse suspicion if they are
followed by pain in the neck or back or neurological
symptoms in the limbs
Eisenstein S, Marsy WE. Injuries of the spine. Apley’s System of Orthopaedics and Fractures. 9th edition. 2010
10. Signs & Symptoms Suggestive of Spine Trauma
• Respiratory distress
• Tenderness at the site of injury on spinal column
• Pain along the spinal column with movement
• Deformity of the spine (rare)
• Numbness, weakness or tingling in the arms or legs
• Loss of sensation or paralysis in the upper or lower extremity
• Incontinence or loss of bowel or bladder control
Eisenstein S, Marsy WE. Injuries of the spine. Apley’s System of Orthopaedics and Fractures. 9th edition. 2010
11. A general physical examination is done with the patient
supine
ABC!
Spinal shock & neurogenic shock
Neurogenic shock
Peripheral vessels dilate hypotension, but the heart doesn’t
respond by increasing its rate
Paralysis, warm and well-perfused peripheral areas,
bradycardia and hypotension with a low diastolic blood
pressure.
Spinal shock occurs when the spinal cord fails temporarily
following injury
Below the level of the injury, the muscles are flaccid, the
reflexes absent and sensation is lost
Eisenstein S, Marsy WE. Injuries of the spine. Apley’s System of Orthopaedics and Fractures. 9th edition. 2010
12. Diagnosis : physical
exam
Head
Head: laceration, contusion, and palpate for facial fracture
Ear canal: inspect to rule out leakage of spinal fluid or blood
The spinous processes should be palpated from the upper cervical to
the lumbosacral region. A painful spinous process may indicate a
spinal injury
Neck
Any complaint of pain or tenderness indicative of a spinal injury
collar immobilization
Neck motion only after the patient reports no pain or tenderness
during examination of the neck
An assistant should hold the neck steady in a neutral position
Eisenstein S, Marsy WE. Injuries of the spine. Apley’s System of Orthopaedics and Fractures. 9th edition. 2010
13. Diagnosis : physical
exam
Sensory examination:
Sensation to light touch
Pinprick sensibility
Motor strength
Physiological and pathological reflexes
Motor and sensory evaluation of the rectum
and perirectal area
Incontinence of the bowel or bladder suggest a
significant spinal injury
Eisenstein S, Marsy WE. Injuries of the spine. Apley’s System of Orthopaedics and Fractures. 9th edition. 2010
15. Sacral Sparing
Definitions of complete and incomplete SCI are
based on the above ASIA definition with sacral-
sparing.
Complete - Absence of sensory and motor
functions in the lowest sacral segments
Incomplete - Preservation of sensory or
motor function below the level of injury,
including the lowest sacral segments
Oleson CV, et al. Principles of spine trauma care. Rockwood and Green’s Fractures in Adults, 7th
edition. 2010
16. Evaluating Sacral Sparing
Perform a rectal examination to check motor function or sensation at the anal
mucocutaneous junction. The presence of either is considered sacral-
sparing.
Sacral sparing may include the triad of perianal sensation, rectal tone, and
great toe flexion
Oleson CV, et al. Principles of spine trauma care. Rockwood and Green’s Fractures in Adults,
7th edition. 2010
17. Imaging
X-ray examination (in secondary survey) of the spine
is mandatory for:
All accident victims complaining of pain or stiffness
in the neck or back or peripheral paraesthesiae
All patients with head injuries or severe facial
injuries
Patients with rib fractures or severe seat-belt
bruising
Severe pelvic or abdominal injuries
Accident victims who are unconscious
Elderly people
Patients with known vertebral pathology (e.g.
ankylosing spondylitis)
18. Imaging
Minimum of movement and manipulation
Apart from AP and lateral views:
Open-mouth views: C1 and C2
CT structural damage of individual vertebrae and
displacement of bone fragments into the vertebral
canal
MRI IV discs, ligamentum flavum and neural
structures
indicated for all patients with neurological signs
and those who are considered for surgery
19. Compression Fracture
Subtypes of compression fractures:
Type A:
Fracture of both endplates
Type B:
Fracture of superior endplate
Type C:
Fracture of inferior endplate
Type D:
Both endplates intact
20. Burst Fracture
•Type A
Fracture of both end-
plates
•Type B
Fracture of the superior
end-plate
•Type C
Fracture of the inferior
end-plate
•Type D
Burst rotation
•Type E
Burst lateral flexion
23. Classification of Neurological
Function
Sensory Motor
A Absent Absent
B Present Absent
C Present Active but not useful
(grade 2-3)
D Present Active and useful
(grade 4)
E Normal Normal
Frankel Classification Grading System
24. ASIA Impairment Scale
ASIA
Grade
Clinical state (below level of injury)
A Complete Complete: no sensory or motor function preserved in
sacral segments S4 – S5
B Sensory
incomplete
Incomplete: sensory, but no motor function in sacral
segments
C Motor
incomplete
Incomplete: motor function preserved below level and
power graded < 3
D Motor
incomplete
Incomplete: motor function preserved below level and
power graded 3 or more
E Normal Normal: sensory and motor function normal
28. Principles of Diagnosis and Initial
Management
Early management
ABCD then assessment of spinal injury
The spine immobilized until the patient has
been resuscitated and other life-threatening
injuries have been identified and treated
Immobilization is abandoned only when
spinal injury has been excluded by clinical
and radiological assessment
Eisenstein S, et al. Injuries of the spine. Apley’s System of Orthopaedics and Fractures. 9th
edition. 2010
29. Initial Temporary Immobilization
Quadruple immobilization
Backboard, sandbags, forehead tape, semirigid collar
Scoop stretcher, spine board, log-roll
Eisenstein S, et al. Injuries of the spine. Apley’s System of Orthopaedics and Fractures. 9th
edition. 2010
30. Corticosteroid
National Acute Spinal Cord Injury Study I, II, and III Protocols
Methylprednisolone bolus 30mg/kg infusion 5.4mg/kg/h
Infusion for 24h if bolus given within 3 hours of injury
Infusion for 48h if bolus given within 3-8 hours after injury
No benefit if >8h
> 8 hr the consensus is clear that there is no indication for steroid
use
Oleson CV, et al. Principles of spine trauma care. Rockwood and Green’s Fractures in Adults, 7th
edition. 2010
31. Principles of definitive treatment
The objectives of treatment:
To preserve neurological function;
To minimize a perceived threat of neurological
compression;
To stabilize the spine;
To rehabilitate the patient.
The indications for urgent surgical stabilization are:
An unstable fracture with progressive neurological deficit
and/or MRI signs of likely further neurological deterioration
Controversially an unstable fracture in a patient with
multiple injuries
Eisenstein S, et al. Injuries of the spine. Apley’s System of Orthopaedics and Fractures. 9th
edition. 2010
33. Surgical
The only consistent indication for surgical
treatment skeletal disruption in the
presence of a progressive neurological
deficit.
Unstable injuries
LEVEL
CORRESPONDING STRUCTURE
C2-3
Mandible
C3
Hyoid cartilage
C4-5
Thyroid cartilage
C6
Cricoid cartilage
C7
Vertebral prominence
T3
Spine of scapula
T7
Xiphoid, tip of scapula
T10
Umbilicus
L1
End of spinal cord
L3
Aorta bifurcation
L4
Iliac creast
COMPRESSION FRACTURE: It is a failure under compression of the anterior column. The middle column is intact and acts as a hinge. There may be a partial failure of the posterior column, indicating the tension forces at that level. Competent middle column prevents the fracture from subluxation or compression of the neural elements by retropulsion of the fragments of the posterior wall into the canal.
Four subtypes of compression fractures can be identified:
Type A - involvement of both end plates
Type B - involvement of superior end plate
Type C - inferior end plate
Type D - buckling of anterior cortex w/ both end plates intact.
BURST FRACTURE: The burst fracture results from failure under axial load of both the anterior and the middle columns originating at the level of one or both end-plates of the same vertebra. Five different types of burst fractures can be described (see the picture below).Type A: Fracture of both end-plates. The bone is retropulsed into the canal.
Type B: Fracture of the superior end-plate. It is common and occurs due to a combination of axial load with flexion.
Type C: Fracture of the inferior end-plate.
Type D: Burst rotation. This fracture could be misdiagnosed as a fracture-dislocation. The he mechanism of this injury is a combination of axial load and rotation.
Type E: Burst lateral flexion. This type of fracture differs from the lateral compression fracture in that it presents an increase of the interpediculate distance on anteroposterior roentgenogram.