The Significance of Bacterial and Fungal Coinfection in the Setting of Viral ...Texas Children's Hospital
Keystone ECMO meeting 2018: To better characterize the frequency of bacterial and/or fungal coinfections in patients with viral pneumonias placed on ECMO and to understand their impact on mortality.
The Significance of Bacterial and Fungal Coinfection in the Setting of Viral ...Texas Children's Hospital
Keystone ECMO meeting 2018: To better characterize the frequency of bacterial and/or fungal coinfections in patients with viral pneumonias placed on ECMO and to understand their impact on mortality.
Need To Protect Childbearing Age Girls against Rubellapaperpublications3
Abstract: Rubella, though a mild skin infection but show disastrous effects during pregnancy and causes damage to fetus. The disease is vaccine- preventable diseases can manifest with severe Teratogenic effects in fetus known as congenital rubella syndrome (CRS) due to primary maternal infection such as heart disorders, blindness, deafness or other life threatening organ disorders. During pregnancy, explore to disease can lead to disastrous results such as bad obstetric history (BOH), repeated pregnancy loss (RPL) or may cause deformities in fetuses whereas it also responsible for infertility and maternal mortality. In the study124 teenage girls and 176 women of different background were selected, out of them 3.23% girls and 11.36 % women were found susceptible and were at risk to have Rubella infection. In the study it was detected that immunity against Rubella was decreasing with increasing age, i.e. the vaccination in childbearing age should be included in schedule.
Need To Protect Childbearing Age Girls against Rubellapaperpublications3
Abstract: Rubella, though a mild skin infection but show disastrous effects during pregnancy and causes damage to fetus. The disease is vaccine- preventable diseases can manifest with severe Teratogenic effects in fetus known as congenital rubella syndrome (CRS) due to primary maternal infection such as heart disorders, blindness, deafness or other life threatening organ disorders. During pregnancy, explore to disease can lead to disastrous results such as bad obstetric history (BOH), repeated pregnancy loss (RPL) or may cause deformities in fetuses whereas it also responsible for infertility and maternal mortality. In the study124 teenage girls and 176 women of different background were selected, out of them 3.23% girls and 11.36 % women were found susceptible and were at risk to have Rubella infection. In the study it was detected that immunity against Rubella was decreasing with increasing age, i.e. the vaccination in childbearing age should be included in schedule.
In this presentation, an overview regarding the causes, risk factors, complications and symptoms related to cellular as well as physiological changes seen in pneumonia is to be discussed.
Childhood demyelinating syndromes
In the past decade, the number of studies related to demyelinating diseases in children has exponentially increased. Demyelinating disease in children may be monophasic or chronic. Typical monophasic disorders in children are acute disseminated encephalomyelitis and clinically isolated syndromes, including optic neuritis and transverse myelitis. However, some cases of acute disseminated encephalomyelitis or clinically isolated syndrome progress to become chronic disorders, including multiple sclerosis and neuromyelitis optica. This review summarizes the current knowledge on monophasic and chronic demyelinating disorders in children, focusing on an approach to diagnosis and management.
Epidemic, Endemic, and Pandemic Occurrence of Disease(s)One aspect.docxelishaoatway
Epidemic, Endemic, and Pandemic Occurrence of Disease(s)
One aspect of epidemiology is the study of the epidemic, endemic, and pandemic occurrence of disease(s).
Some critics may argue diseases and conditions such as bird flu are endemic in many countries, and some may argue human immunodeficiency virus (HIV) or AIDS is a series of epidemics.
Research about the various epidemic, endemic, and pandemic occurrence of disease(s).
Based on your research and understanding, answer the following questions:
At what point does a disease become an epidemic, endemic, or pandemic? What are the parameters that define each of these states of a disease's effect?
Do you agree that bird flu, HIV, or AIDS could be described as a series of epidemics? Why or why not?
Should we study epidemiology and disease control as a complement to the provision of healthcare services? Why or why not?
Disease control has evolved since the discoveries and achievements of these epidemiological pioneers
—
Hippocrates, John Snow, Pasteur, and Koch. Explain the impact of at least one major historical contribution on the current status of epidemiological practices. How can history potentially shape and impact our future work in public health and clinical medicine? Explain.
***PLEASE.... Zero Plagiarims and cited references.....lthanks
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
3. Introduction
Very rare but could be serious
Complicated and challenging diagnostic process
PCR from CSF?
Wright PF, Webster RG. Orthomyxoviruses. In: Knipe DM, Howley PM. Field’s virology, 4th ed. Philadelphia: Lippincott Raven, 2001: 1533–79
Meijer, W. J., Linn, F. H., Wensing, A. M., Leavis, H. L., van Riel, D., GeurtsvanKessel, C. H., ... & Murk, J. L. (2016). Acute influenza virus-associated encephalitis and encephalopathy in adults: a challenging
diagnosis. JMM Case Reports, 3(6).
4. Epidemiology
mainly affect children (Gu et al., 2013)
Incidence: 0.21 per million population per year (Hjalmarsson et al., 2009)
IAE appears to have increased after the 2009 H1N1 influenza A virus pandemic,
with an estimated 12 per million of symptomatic 2009 H1N1 cases (Glaser et al.,
2012; Gu et al., 2013)
Influenza virus has been identified as the (possible) pathogen in 5–9 % of cases
(Glaser et al., 2006; Koskiniemi et al., 2001; Rantalaiho et al., 2001).
5. Pathogenesis
Inflammation & infection
Elevated concentrations of cytokines and anti-influenza antibodies in CSF
The presence of avian influenza virus receptors and human influenza virus
receptors on neurons, astrocytes and epithelial cells in the brain
Meijer, W. J., Linn, F. H., Wensing, A. M., Leavis, H. L., van Riel, D., GeurtsvanKessel, C. H., ... & Murk, J. L. (2016). Acute influenza virus-associated encephalitis and encephalopathy in adults: a challenging
diagnosis. JMM Case Reports, 3(6).
6. Meijer, W. J., Linn, F. H., Wensing, A. M., Leavis, H. L., van Riel, D., GeurtsvanKessel, C. H., ... & Murk, J. L. (2016). Acute influenza virus-associated encephalitis and encephalopathy in adults: a challenging
diagnosis. JMM Case Reports, 3(6).
7. Prevention and Treatment
Influenza vaccination in healthy adults has an efficacy of 59–83 % in preventing
influenza infection (Osterholm et al., 2012).
Antiviral agents
Immunomodulatory therapy (corticosteroids)
Meijer, W. J., Linn, F. H., Wensing, A. M., Leavis, H. L., van Riel, D., GeurtsvanKessel, C. H., ... & Murk, J. L. (2016). Acute influenza virus-associated encephalitis and encephalopathy in adults: a challenging
diagnosis. JMM Case Reports, 3(6).
8. Prognosis
Full recovery in 61 %
Recovery in patients with brain abnormality: 24 %
Recovery in patients without brain abnormality: 60 %
Meijer, W. J., Linn, F. H., Wensing, A. M., Leavis, H. L., van Riel, D., GeurtsvanKessel, C. H., ... & Murk, J. L. (2016). Acute influenza virus-associated encephalitis and encephalopathy in adults: a challenging
diagnosis. JMM Case Reports, 3(6).
9. Summary
Rare but serious
In immunocompetent patients
Inflammatory and infection
PCR in CSF
Prevention by vaccine
Treatment: Antiviral agents and immunomodulatory therapy (corticosteroid)
Prognosis depend on imaging lesions