A proton pump inhibitor (PPI) used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. It is available in strengths of 5, 10, and 20 mg.

1. ILAPRAZOLE

2. The stomach functions to store, dissolve, and partial breakdown macromolecules. The
glands of the stomach secrete a strong acid, hydrochloric acid (HCl), and protein-
digesting enzymes. The stomach acid also serves to kill bacteria entering the organ.

3. GASTRIC PARIETAL CELL
The majority of stomach
parietal cells reside in the
corpus. Parietal cells secrete
HCl in response to gastrin from
G cells, histamine from ECL
cells, or acetylcholine (ACh)
from the vagus nerve. It can
also be stimulated by protein
ingestion, distension of the
stomach, or even the thought of
food.

6. Gastric Acid ( Hcl ) associated
disorders and disease

8. Acid-related Diseases
Acid-related diseases involve a variety of disorders that can affect the
esophagus, stomach and duodenum.
DYSPEPSIA
GERD
Peptic Ulcer Disease
Duodenal Ulcers
Gastric Ulcers & NSAID-induced
Mucosal Injury
Helicobacter pylori & NSAID Use
Stress-related Mucosal Disease

11. Omeprazole
Lansoprazole
Pantoprazole
Esomeprazole
Rabeprazole
Dexlansoprazole
Ilaprazole

13. Ilaprazole
Ilaprazole is developed by IL-YANG Pharmaceutical (Korea),

14. ADIZA 10 MG Abbott 79.90/- (Max Retail Price)
ILADAC Cadila (Alidac Fortiza) 80/- (Max Retail Price)
ILADAY Mankind 69.0/- (Max Retail Price)
ILAGATE Astraea
ILAGATE-DSR Astraea 10's (97 INR)
ILAPRO Ajanta 80./- (Max Retail Price)
CHEKCID 10 MG Aristo 69.50 (Max Retail Price)

15. REFERENCES:-
1. http://www.medscape.com/viewarticle/705418_5
2. http://www.ncbi.nlm.nih.gov/pubmed/15496215
3. http://refluxdefense.com/images/Pathology-Low-Acid-Level-Diseases.gif
4. http://www.google.co.in/imgres?
imgurl=http://refluxdefense.com/images/Pathology-Low-Acid-Level-
Diseases.gif&imgrefurl=http://refluxdefense.com/heartburn_GERD_articles/side
-effects-antacids-and-acid-
blockers.html&h=662&w=666&tbnid=7pEcZyPxb2e_YM:&zoom=1&docid=k220
6-TU18oVmM&ei=oElDVebYEuGsmAW24oH4Bg&tbm=isch&client=firefox-
a&ved=0CBwQMygAMAA
5.http://pathology2.jhu.edu/beweb/images/ppi.gif
6. http://www.refluxy.com/proton-pump-inhibitors.html
7. http://www.iosrjournals.org/iosr-jdms/papers/Vol13-issue1/Version-
7/D013170712.pdf
8. www.cimsasia.com/India/drug/info/