Hutchinson's pupil is named after Sir Jonathan Hutchinson and refers to a dilated, unreactive pupil caused by compression of the oculomotor nerve due to an intracranial mass lesion. Hutchinson's triad is a common presentation of congenital syphilis consisting of interstitial keratitis, Hutchinson incisors, and eighth nerve deafness. Hutchinson's sign refers to a skin lesion on the tip of the nose that precedes herpes zoster ophthalmicus due to shared innervation of the cornea and nose tip. Hutchinson's disease, also known as Abercrombie's tumour, involves a malignant tumor that often metastasizes to the liver, lungs, and bones. Pro

1. HUTCHINSON’S - INTERESTING FACTS
1. HUTCHINSON'S PUPIL ( NAMED AFTER SIR JONATHAN HUCHINSON (1828–1913).)
• THE PUPIL ON THE SIDE OF AN INTRACRANIAL MASS LESION IS DILATED
AND UNREACTIVE TO LIGHT, DUE TO COMPRESSION OF THE OCULOMOTOR NERVE ON THAT
SIDE
2. HUTCHINSON'S TRIAD
• IT IS A COMMON PATTERN OF PRESENTATION FOR CONGENITAL SYPHILIS
CONSISTS OF THREE PHENOMENA:
INTERSTITIAL KERATITIS,
HUTCHINSON INCISORS,
EIGHTH NERVE DEAFNESS
3. HUTCHINSON'S SIGN
• A SKIN LESION ON THE TIP OF THE NOSE PRECEDES THE DEVELOPMENT OF OPHTHALMIC HERPES
ZOSTER.
OCCURS BECAUSE THE NASOCILIARY BRANCH OF THE TRIGEMINAL NERVE INNERVATES BOTH
THE CORNEA AND THE TIP OF THE NOSE.
4. HUTCHISON'S DISEASE
(ABERCROMBIE'S TUMOUR , HUTCHISON'S SYNDROME/TUMOUR,PARKER'S SYNDROME,PEPPER’S
DISEASE,SMITH’S SYNDROME)
THIS SYNDROME CONSISTS OF A MALIGNANT TUMOR, OFTEN METASTASING TO THE LIVER, LUNGS, AND BONES.
5. PROGERIA ( "HUTCHINSON–GILFORD PROGERIA SYNDROME”)
• EXTREMELY RARE, SEVERE, GENETIC CONDITION WHEREIN SYMPTOMS RESEMBLING ASPECTS
OF AGING ARE MANIFESTED AT AN EARLY AGE.
• IT IS A GENETIC CONDITION THAT OCCURS AS A NEW MUTATION AND IS NOT USUALLY INHERITED