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HPV VACCINATION
Dr Nupur Gupta
NATURAL HISTORY OF HPV INFECTION
HPV TYPES
HPV & CERVICAL CANCER
HPV & CANCER
HPV & OTHER CANCERS
PRIMARY PREVENTION
QUADRIVALEN
T
HPV 6,11,16,18
BIVALENT
HPV 16,18
WHO NEEDS IT & WHAT IS THE DOSE?
 9 to 14 years, 2 doses (CDC)
 15 to 26 years, three doses (CDC)
 9 to 45 years (US FDA)
WHO SHOULDN’T GET THE VACCINE?
 PREGNANCY
 SEVERELY ILL
 REACTION AT ITS LAST
DOSE
ANY SIDE EFFECTS?
 COMMON – SORENESS, SWELLING AT INJECTION SITE
 OCCASIONAL – N, V, DIZZINESS, FAINTING
IS IT EFFECTIVE IF YOU ARE SEXUALLY
ACTIVE?
 YES
 PROTECTION FROM OTHER STRAINS
 BUT CANNOT TREAT EXISTING HPV INFECTION
WHAT TO DO IF YOU ARE NOT IN
RECOMMENDED VACCINE AGE GROUP?
 REGULAR PAP
 USE CONDOMS (ORAL, VAGINAL OR ANAL SEX)
 AVOID SMOKING
 WARNING SIGN: POSTCOITAL OR POSTMENOPAUSAL
BLEEDING
DO WOMEN STILL NEED PAP TEST?
 YES
 IT HASN’T REPLACED PAP TESTS
SECONDARY PREVENTION: EARLY DETECTION
SCREENING GUIDELINES
VACCINE + SCREEN
 COMBINING HPV VACCINE WITH SCREENING
WILL HAVE THE GREATEST IMPACT ON REDUCING THE
FUTURE BURDEN OF CERVICAL CANCER
MYTHS RELATED TO HPV
HPV IS RARE
 Accounts for maximum number of STIs worldover
HPV is transmitted through AIR
 Infected skin or mucus membrane – mouth, anus, cervix,
vagina or penis
Only one type of HPV causes cancer
 Low Risk (6,11)
 High Risk (16,18, 31,33, 45,52,58)
If you're not having sex, don't worry about it
 Any genital contact can spread an HPV infection, so anyone
with a sexual history could be at risk.
Having more sexual partners, and having sex at an earlier
age, could increase the overall risk.
Vaccine wont work if infected with HPV
 Vaccine prevents against other strains even if
infected with one or two strains
Contracting HPV doesn’t mean you will not get
again
 There are more than 100 strains of HPV. Having immunity
to a single strain doesn't preclude a person from being
infected with another.
HUMAN PAPILLOMA VIRUS
HPV vaccination against Cervical Cancer

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HPV vaccination against Cervical Cancer

  • 2. NATURAL HISTORY OF HPV INFECTION
  • 4. HPV & CERVICAL CANCER
  • 6. HPV & OTHER CANCERS
  • 8. WHO NEEDS IT & WHAT IS THE DOSE?  9 to 14 years, 2 doses (CDC)  15 to 26 years, three doses (CDC)  9 to 45 years (US FDA)
  • 9. WHO SHOULDN’T GET THE VACCINE?  PREGNANCY  SEVERELY ILL  REACTION AT ITS LAST DOSE
  • 10. ANY SIDE EFFECTS?  COMMON – SORENESS, SWELLING AT INJECTION SITE  OCCASIONAL – N, V, DIZZINESS, FAINTING
  • 11. IS IT EFFECTIVE IF YOU ARE SEXUALLY ACTIVE?  YES  PROTECTION FROM OTHER STRAINS  BUT CANNOT TREAT EXISTING HPV INFECTION
  • 12. WHAT TO DO IF YOU ARE NOT IN RECOMMENDED VACCINE AGE GROUP?  REGULAR PAP  USE CONDOMS (ORAL, VAGINAL OR ANAL SEX)  AVOID SMOKING  WARNING SIGN: POSTCOITAL OR POSTMENOPAUSAL BLEEDING
  • 13. DO WOMEN STILL NEED PAP TEST?  YES  IT HASN’T REPLACED PAP TESTS
  • 16. VACCINE + SCREEN  COMBINING HPV VACCINE WITH SCREENING WILL HAVE THE GREATEST IMPACT ON REDUCING THE FUTURE BURDEN OF CERVICAL CANCER
  • 18. HPV IS RARE  Accounts for maximum number of STIs worldover HPV is transmitted through AIR  Infected skin or mucus membrane – mouth, anus, cervix, vagina or penis
  • 19. Only one type of HPV causes cancer  Low Risk (6,11)  High Risk (16,18, 31,33, 45,52,58) If you're not having sex, don't worry about it  Any genital contact can spread an HPV infection, so anyone with a sexual history could be at risk. Having more sexual partners, and having sex at an earlier age, could increase the overall risk.
  • 20. Vaccine wont work if infected with HPV  Vaccine prevents against other strains even if infected with one or two strains Contracting HPV doesn’t mean you will not get again  There are more than 100 strains of HPV. Having immunity to a single strain doesn't preclude a person from being infected with another.

Editor's Notes

  1. Even if you already have one strain of HPV, you could still benefit from the vaccine because it can protect you from other strains that you don't yet have. However, none of the vaccines can treat an existing HPV infection. The vaccines protect you only from specific strains of HPV you haven't been exposed to already