Archaeological evidence shows that herbal medicine dates back 60,000 years to the Paleolithic age. Some of the earliest written records of herbal medicine include a 5000-year-old Sumerian clay slab mentioning 250 plants and Egypt's Ebers Papyrus from 1550 BC describing over 700 plant-based compounds. Ancient Greek, Chinese, Indian, and Arab cultures also documented medicinal plants in early herbals and texts, with the Sushruta Samhita from 6th century BC India describing 700 medicinal plants. Throughout history, monasteries, physicians, and civilizations identified healing properties of plants and passed this knowledge between societies, upgrading old uses and discovering new ones to develop herbal medicine
Ethnobotany and Ethnopharmacology-Approaches of Traditional Medicine Studies, Traditional use & management of medicinal plants in Asian countries, Application of Ethnobotany to community conservation and medicinal plant resource management
The importance of medicinal plants in the treatment of a variety of human ailments man has been dependent on the higher plants as a source of food and medicine.
The term “herbal drugs” denotes plants or plant parts that have been converted into phytopharmaceuticals by means of simple processes involving harvesting, drying, and storage.
Ethnobotany and Ethnopharmacology-Approaches of Traditional Medicine Studies, Traditional use & management of medicinal plants in Asian countries, Application of Ethnobotany to community conservation and medicinal plant resource management
The importance of medicinal plants in the treatment of a variety of human ailments man has been dependent on the higher plants as a source of food and medicine.
The term “herbal drugs” denotes plants or plant parts that have been converted into phytopharmaceuticals by means of simple processes involving harvesting, drying, and storage.
medicinal properties of Terminallia chebula(harro) with its habit and habbitat,microscopic character, macroscopic character and plant have pharmacological properties like antioxidant,anticancer, cardioprotective activity,antidaibetic,antibactarial,antifungal,antiviral and anti-infammatrory properties.
The term "traditional medicine" refers to ways of protecting and restoring health that existed before the arrival of modern medicine. As the term implies, these approaches to health belong to the traditions of each country, and have been handed down from generation to generation. Traditional systems in general have had to meet the needs of the local communities for many centuries as a primary health care system.
Standardization of herbal drugs refers to “confirmation of its identity and determination of its quality, purity and detection of nature of adulterant by various parameters”.
unani or Unani medicine (Urdu: طب یونانی tibb yūnānī) is the term for Perso-Arabic traditional medicine, practiced in Mughal India and in Muslim culture in South Asia and modern day Central Asia. The term is derived from Arabic Yūnānī "Greek", as the Perso-Arabic system of medicine was in turn based on the teachings of the Greek physicians Hippocrates and Galen.The medical tradition of medieval Islam was introduced to India by the 13th century with the establishment of the Delhi Sultanate and it took its own course of development during the Mughal Empire , influenced by Indian medical teachings of Sushruta and Charaka.
Nutraceuticals chapter of Advance Pharmacognosy 1 of M Pharm syllabus.
This presentation involves Introduction to Nutraceuticals,
Classification of Nutraceuticals, Herbs as a food, Inorganic /mineral supplements, brief benefits of vitamin supplements, digestive enzymes and its example, use of cereals and Grains, importance of Antioxidants and Polyunsaturated fatty acids, an example of formulation and standardization of Multivitamin Tablets, what all regulatory requirement we need to manufacture Nutraceuticals and FSSAI guidelines for Nutraceuticals, sources- mediinal use - marker compound of some usually used Nutraceuticals.
Medicinal plants history A Lecture By Mr Allah Dad Khan Former DG Agriculture...Mr.Allah Dad Khan
Medicinal plants history A Lecture By Mr Allah Dad Khan Former DG Agriculture Extension Khyber Pakhtun Khwa Province & Visiting Professor Agriculture University Peshawar Pakistan
medicinal properties of Terminallia chebula(harro) with its habit and habbitat,microscopic character, macroscopic character and plant have pharmacological properties like antioxidant,anticancer, cardioprotective activity,antidaibetic,antibactarial,antifungal,antiviral and anti-infammatrory properties.
The term "traditional medicine" refers to ways of protecting and restoring health that existed before the arrival of modern medicine. As the term implies, these approaches to health belong to the traditions of each country, and have been handed down from generation to generation. Traditional systems in general have had to meet the needs of the local communities for many centuries as a primary health care system.
Standardization of herbal drugs refers to “confirmation of its identity and determination of its quality, purity and detection of nature of adulterant by various parameters”.
unani or Unani medicine (Urdu: طب یونانی tibb yūnānī) is the term for Perso-Arabic traditional medicine, practiced in Mughal India and in Muslim culture in South Asia and modern day Central Asia. The term is derived from Arabic Yūnānī "Greek", as the Perso-Arabic system of medicine was in turn based on the teachings of the Greek physicians Hippocrates and Galen.The medical tradition of medieval Islam was introduced to India by the 13th century with the establishment of the Delhi Sultanate and it took its own course of development during the Mughal Empire , influenced by Indian medical teachings of Sushruta and Charaka.
Nutraceuticals chapter of Advance Pharmacognosy 1 of M Pharm syllabus.
This presentation involves Introduction to Nutraceuticals,
Classification of Nutraceuticals, Herbs as a food, Inorganic /mineral supplements, brief benefits of vitamin supplements, digestive enzymes and its example, use of cereals and Grains, importance of Antioxidants and Polyunsaturated fatty acids, an example of formulation and standardization of Multivitamin Tablets, what all regulatory requirement we need to manufacture Nutraceuticals and FSSAI guidelines for Nutraceuticals, sources- mediinal use - marker compound of some usually used Nutraceuticals.
Medicinal plants history A Lecture By Mr Allah Dad Khan Former DG Agriculture...Mr.Allah Dad Khan
Medicinal plants history A Lecture By Mr Allah Dad Khan Former DG Agriculture Extension Khyber Pakhtun Khwa Province & Visiting Professor Agriculture University Peshawar Pakistan
Biography of medicinal plants A Lecture by Mr Allah Dad Khan Former DG Agri E...Mr.Allah Dad Khan
Biography of medicinal plants A Lecture by Mr Allah Dad Khan Former DG Agri Extension KPK/Visiting Professor the University of Agriculture Peshawar Pakistan
History of medicinal plant use A Presentation By Mr Allah Dad Khan Former Di...Mr.Allah Dad Khan
History of medicinal plant use A Presentation By Mr Allah Dad Khan Former Director General Agriculture Extension KPK Province and Visiting Professor the University of Agriculture Peshawar Pakistan
Timeline of Marijuana Legalization.pptxAlice Wilson
The history of marijuana legalization: from the ancient times to the current ones. Get to know about when the beneficial qualities of marijuana were discovered, when and why cannabis was banned and how finally it became legalized in most US states.
Traditional medicine (also known as indigenous or folk medicine) comprises medical aspects of traditional knowledge that developed over generations within the folk beliefs of various societies before the era of modern medicine.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
1. Herbal Cultivation
History of Herbal Medicine
Herbal Medicine refers to the use of plant or plant extracts for medicinal purposes. It is
otherwise known as Phytomedicine.
History of Herbal Medicine
Archaeological evidence indicates that the use of medicinal plants dates back to the
Paleolithic age approximately 60,000 years ago.
The oldest written evidence of herbal medicine has been found on a Sumerian Clay Slab,
approximately 5000 years ago. It comprises 12 methods of drug preparations referring to
over 250 different plants.
Some ancient cultures wrote about plants and their medical uses in books called herbals.
Egypt’s mentioned the herbs in Egyptian medical papyri. Among all papyri, the oldest,
lengthiest, and most important medical papyri is Ebers Papyrus which dates from 1550 BC
and covers more than 700 compounds, mainly of plant origin.
The earliest known Greek herbals came from Theophastrus who wrote: "Historia
Plantarum" having the classification of 500 medicinal plants.
Seeds, likely used for herbalism were found in archaeological sites of Bronze age China
dating from the Shang Dynasty (1600 BC)
Over a hundred of the 224 compounds mentioned in the Huangdi Neijing, an early Chinese
medical text.
The Chinese book on root and grasses “Pen T Sao” written by Emperor Shen Nung Circa in
2500 BC has 365 drugs made of plants.
2. Herbal Cultivation
Benedictine monasteries were the primary source of herbal medical knowledge
in Europe and England during the Early Middle Ages.
A great scholar, Avicenna of the Arabian School wrote ‘The Canon of Medicine’ which
became the standard medical reference work of the Arab world. This book includes a
description of 760 medicinal plants and the medicine that could be derived from them.
In India, the Ayurvedic system of medicine is the oldest system of medicine which dates
back to 4000 BC.
The earliest Sanskrit writings such as the Rig Veda and Atharva Veda are some of the
earliest available documents detailing the medical knowledge that formed the basis of the
Ayurveda system.
Many other herbs and minerals used in Ayurveda were later described by ancient Indian
herbalists such as Charaka and Sushruta during the 1st millennium BC.
The Sushruta Samhita attributed to Sushruta in the 6th century BC describes 700
medicinal plants, 64 preparations from mineral sources, and 57 preparations based on
animal sources.
Siddha's system of medicine is also one of the oldest traditional medicines. It is practiced
mostly in Tamil Nadu. According to the tradition, eighteen Siddhars were supposed to
have contributed to the development of Siddha medicine.
In every period, every successive century from the development of humankind and advanced
civilizations, the healing properties of certain medicinal plants were identified, noted, and
conveyed to the successive generations. The benefits of one society were passed on to another,
which upgraded the old properties, discovered new ones, till the present days. The continuous and
perpetual people's interest in medicinal plants has brought about today's modern and
sophisticated fashion of their processing and usage.
M.Priyadharshana
14/3/2021