DOI:10.21276/ijlssr.2016.2.4.20
ABSTRACT- The present investigation was carried out to the effect of dimethoate on histopathological changes in
kidney of freshwater fish, Garra mullya. Fishes was exposed to sub lethal concentration of dimethoate (0.0238ppm of
96hrs.) for 7, 14, 21 days. Fishes exposed to dimethoate were characterized by loosening of haemopoietic tissue,
uriniferous tubules have lost their original appearance, vacuolated cytoplasm, degeneration in the epithelial cells of renal
tubule, narrowing of the tubular lumen and damaged glomeruli. The lesions in the vital organ might have resulted in
physiological and metabolical dysregulations. In chronic treatment of dimethoate exposure may pose serious threat to fish
health and affect their population. Key-words- Dimethoate, Histopathology, Kidney, Garra mullya
Borane V R*
Department of Zoology Jijamata Arts, Science and Commerce College, Nandurbar, Maharashtra, India
ABSTRACT- The present investigation was carried out to the effect of Dimethoate on histopathological changes in liver
of freshwater fish, Garra mullya using standard methods. Fish was exposed to sub lethal concentration of Dimethoate
(0.0238ppm of 96hrs) for 7, 14, and 21days. Administration of pesticide to determine lesion of liver as indicators of tissue
damage. Histopathological changes in liver ranged from vacuolization, necrosis, fibrosis of perivascular region and
disposition of yellow brown grains at different time of exposure. Liver histology exhibited various abnormalities,
including hyperplasia, nuclear pyknosis, fatty necrosis and degeneration of hepatocytes leading to tumor and syncytium
formation, which are the indicative of carcinogenesis. In chronic treatment of dimethoate exposure may pose serious
threat to fish health and affect their population.
Key-words- Dimethoate, Histopathology, Liver, Garra mullya
The International Journal of Engineering & Science is aimed at providing a platform for researchers, engineers, scientists, or educators to publish their original research results, to exchange new ideas, to disseminate information in innovative designs, engineering experiences and technological skills. It is also the Journal's objective to promote engineering and technology education. All papers submitted to the Journal will be blind peer-reviewed. Only original articles will be published.
The papers for publication in The International Journal of Engineering& Science are selected through rigorous peer reviews to ensure originality, timeliness, relevance, and readability.
DOI: 10.21276/ijlssr.2016.2.4.10
bio-indicators. The present study is focused on the effective use of L. rohita, an economically significant carp as a
bio-indicator of zinc pollution through its several physiological, histopathological biomarkers. Primarily, acute toxicity
test is performed in which the carp fingerlings are exposed to different concentrations (10, 20, 40, 80, 160, 320 ppm) of
zinc sulphate. 96 hour LC50 value is determined to be 100 ppm. It is taken as lethal concentration and the fishes are
exposed to it for a period of 96 hours during which wide range of behavioural abnormalities are evidenced like general
hyperactivity, surfacing activity, hyper-opercular activity, and erratic swimming pattern. It is followed by loss of balance
and convolutions. One fifth of the lethal concentration is taken (i.e., 10 ppm) as sub-lethal concentration and fishes are
exposed to it for a period of 15 days during which growth, behaviour, oxygen consumption, histopathology, hematology
and genotoxicity are studied. Negative growth performance is observed with insignificant length increment up to 0.24 %
and significant weight reduction up to -2.38 %. Wide range of behavioural abnormalities are evidenced which includes,
erratic swimming, hyperactivity, surfacing activity and depression in appetite. Besides, general body discolouration and
haemorrhage are observed as well. Rate of oxygen consumption showed a time dependant decrease which ranged up to
-49.10%. Gills of the fishes are shown to have conspicuous histopathological alterations like lamellar necrosis, lamellar
fusion, lamellar erosion, epithelial lifting and epithelial swelling. Key-words- Bioindicator, L. rohita, Zinc sulphate, Growth, Behaviour, Oxygen Consumption, Histopathology
Non invasive high resolution in vivo imaging of alpha-naphthylisothiocyanate
(ANIT) induced hepatobiliary toxicity in STII medaka
Ron Hardman∗, Seth Kullman, Bonny Yuen, David E. Hinton
Duke University, Nicholas School of the Environment and Earth Sciences, Durham, NC 27708, United States
Assessment on Accumulation of Heavy Metals and its Effect on Liver Tissues of...ijtsrd
Heavy metal pollution is a very serious issue in the present world and is caused by release of toxic substances from industrial and domestic sources into the sea water leading to harm marine organisms. Marine fishes are commonly consumed for its nutritional benefits and thus lead to transfer toxic metals into the food chain. Harpodon nehereus is a common and local fish from west coast of Maharashtra with high consumption rate among local population. Fish organs particularly liver being major site of detoxification shows structural alterations on exposure to pollution stress from their surrounding environment. Histopathological examination provides an indication of organ impairment to evaluate the health status of selected fish and the degree of pollution in marine environment. The present research effort was done to evaluate the concentration of heavy metals and to study histopathological alterations in liver tissues of largely consumed fish Harpodon nehereus collected from Sassoon dock, west Coast of Maharashtra, India. The research was carried out during the post-monsoon season of the year. High accumulation of lead 11.8 ± 8.34 mg kg , copper 20.46 ± 11.06 mg kg and Zinc 286.26 ± 114.5 mg kg were observed in liver tissues. Further histopathological study of present investigation reveals heavy damages in liver tissues of Harpodon nehereus representing that the selected fish is under high threat of pollution stress. Archana Oza | Leena Muralidharan "Assessment on Accumulation of Heavy Metals and its Effect on Liver Tissues of Harpodon Nehereus from Mumbai Coast of Maharashtra, India" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-2 , February 2019, URL: https://www.ijtsrd.com/papers/ijtsrd20250.pdf
Paper URL: https://www.ijtsrd.com/biological-science/zoology/20250/assessment-on-accumulation-of-heavy-metals-and-its-effect-on-liver-tissues-of-harpodon-nehereus-from-mumbai-coast-of-maharashtra-india/archana-oza
Borane V R*
Department of Zoology Jijamata Arts, Science and Commerce College, Nandurbar, Maharashtra, India
ABSTRACT- The present investigation was carried out to the effect of Dimethoate on histopathological changes in liver
of freshwater fish, Garra mullya using standard methods. Fish was exposed to sub lethal concentration of Dimethoate
(0.0238ppm of 96hrs) for 7, 14, and 21days. Administration of pesticide to determine lesion of liver as indicators of tissue
damage. Histopathological changes in liver ranged from vacuolization, necrosis, fibrosis of perivascular region and
disposition of yellow brown grains at different time of exposure. Liver histology exhibited various abnormalities,
including hyperplasia, nuclear pyknosis, fatty necrosis and degeneration of hepatocytes leading to tumor and syncytium
formation, which are the indicative of carcinogenesis. In chronic treatment of dimethoate exposure may pose serious
threat to fish health and affect their population.
Key-words- Dimethoate, Histopathology, Liver, Garra mullya
The International Journal of Engineering & Science is aimed at providing a platform for researchers, engineers, scientists, or educators to publish their original research results, to exchange new ideas, to disseminate information in innovative designs, engineering experiences and technological skills. It is also the Journal's objective to promote engineering and technology education. All papers submitted to the Journal will be blind peer-reviewed. Only original articles will be published.
The papers for publication in The International Journal of Engineering& Science are selected through rigorous peer reviews to ensure originality, timeliness, relevance, and readability.
DOI: 10.21276/ijlssr.2016.2.4.10
bio-indicators. The present study is focused on the effective use of L. rohita, an economically significant carp as a
bio-indicator of zinc pollution through its several physiological, histopathological biomarkers. Primarily, acute toxicity
test is performed in which the carp fingerlings are exposed to different concentrations (10, 20, 40, 80, 160, 320 ppm) of
zinc sulphate. 96 hour LC50 value is determined to be 100 ppm. It is taken as lethal concentration and the fishes are
exposed to it for a period of 96 hours during which wide range of behavioural abnormalities are evidenced like general
hyperactivity, surfacing activity, hyper-opercular activity, and erratic swimming pattern. It is followed by loss of balance
and convolutions. One fifth of the lethal concentration is taken (i.e., 10 ppm) as sub-lethal concentration and fishes are
exposed to it for a period of 15 days during which growth, behaviour, oxygen consumption, histopathology, hematology
and genotoxicity are studied. Negative growth performance is observed with insignificant length increment up to 0.24 %
and significant weight reduction up to -2.38 %. Wide range of behavioural abnormalities are evidenced which includes,
erratic swimming, hyperactivity, surfacing activity and depression in appetite. Besides, general body discolouration and
haemorrhage are observed as well. Rate of oxygen consumption showed a time dependant decrease which ranged up to
-49.10%. Gills of the fishes are shown to have conspicuous histopathological alterations like lamellar necrosis, lamellar
fusion, lamellar erosion, epithelial lifting and epithelial swelling. Key-words- Bioindicator, L. rohita, Zinc sulphate, Growth, Behaviour, Oxygen Consumption, Histopathology
Non invasive high resolution in vivo imaging of alpha-naphthylisothiocyanate
(ANIT) induced hepatobiliary toxicity in STII medaka
Ron Hardman∗, Seth Kullman, Bonny Yuen, David E. Hinton
Duke University, Nicholas School of the Environment and Earth Sciences, Durham, NC 27708, United States
Assessment on Accumulation of Heavy Metals and its Effect on Liver Tissues of...ijtsrd
Heavy metal pollution is a very serious issue in the present world and is caused by release of toxic substances from industrial and domestic sources into the sea water leading to harm marine organisms. Marine fishes are commonly consumed for its nutritional benefits and thus lead to transfer toxic metals into the food chain. Harpodon nehereus is a common and local fish from west coast of Maharashtra with high consumption rate among local population. Fish organs particularly liver being major site of detoxification shows structural alterations on exposure to pollution stress from their surrounding environment. Histopathological examination provides an indication of organ impairment to evaluate the health status of selected fish and the degree of pollution in marine environment. The present research effort was done to evaluate the concentration of heavy metals and to study histopathological alterations in liver tissues of largely consumed fish Harpodon nehereus collected from Sassoon dock, west Coast of Maharashtra, India. The research was carried out during the post-monsoon season of the year. High accumulation of lead 11.8 ± 8.34 mg kg , copper 20.46 ± 11.06 mg kg and Zinc 286.26 ± 114.5 mg kg were observed in liver tissues. Further histopathological study of present investigation reveals heavy damages in liver tissues of Harpodon nehereus representing that the selected fish is under high threat of pollution stress. Archana Oza | Leena Muralidharan "Assessment on Accumulation of Heavy Metals and its Effect on Liver Tissues of Harpodon Nehereus from Mumbai Coast of Maharashtra, India" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-2 , February 2019, URL: https://www.ijtsrd.com/papers/ijtsrd20250.pdf
Paper URL: https://www.ijtsrd.com/biological-science/zoology/20250/assessment-on-accumulation-of-heavy-metals-and-its-effect-on-liver-tissues-of-harpodon-nehereus-from-mumbai-coast-of-maharashtra-india/archana-oza
New Spectrophotometric Determination of Tenofovir Disoproxil Fumaratein Bulk ...IOSRJAC
Two new, selective and sensitive visible spectrophotometric methods (method A and B) have been developed for the estimation of Tenofovir disoproxil fumaratein bulk and in pharmaceutical preparations. Method ‘A’ is based on the reaction with wool fast blue, in the presence of buffer at PH 1.5 to form a colored species with a λmax 590nm. Method B is based on the reaction with tropaeoline -00 dye under acidic condition with a λ max 410nm. Beer’s law is obeyed in the concentration range of 50 to 250µg/ml for both the methods. The methods were extended to pharmaceutical formulations and there was no interference form any common pharmaceutical excepients and diluents. The result of analysis has been validated statistically and by recovery studies.
Heavy Metals in organs and endoparasites of Oreochromisniloticus, Sediment an...iosrjce
IOSR Journal of Environmental Science, Toxicology and Food Technology (IOSR-JESTFT) multidisciplinary peer-reviewed Journal with reputable academics and experts as board member. IOSR-JESTFT is designed for the prompt publication of peer-reviewed articles in all areas of subject. The journal articles will be accessed freely online.
ABSTRACT- Aquatic organisms have been considered to concentrate metals several times greater than environmental levels. Fishes have been used for many decades to evaluate the pollution status of water and thus considered as excellent biological indicator of heavy metals in aquatic environments. Heavy metals are natural tress components of the aquatic environment, but their levels have increased due to domestic, industrial, mining and agricultural activities. These heavy metals when accumulated in the fish tissues, they damage and weaken the mechanisms concerned leading to physiological, pathological and biochemical changes. The lead is non essential element while cobalt is an essential element for living organisms but its presence in fresh water in higher concentration are toxic to organism’s brain, liver, ovary, kidney and gills of the fish. The present study was aimed to investigate the changes due to two heavy metals (lead & cobalt) on the activity of the antioxidant enzyme, Catalase (CAT), Reduced glutathione (GSH), and Lipid peroxidation (LPO) in the brain of Danio rerio during 5, 10, 15 and 20 days of exposure period. For this study adult fishes were exposed to four different concentrations viz., 20, 30, 40 and 50 mg/l of cobalt and 5, 9, 13, and 17 mg/l of lead. Key-words- Zebrafish, Lead, Cobalt, Catalase, LPO, Glutathione, Heavy metals
— The formation, species composition and functional role of red algae were studied in the Black Sea's coastal zone. In sublittoral plant communities, red algae are dominant both by their number of species in the phytocenosis and by their active thallus-the one that ensures their high metabolism. Algae with a large specific surface area of thallus can accumulate heavy metals in higher concentrations. In the paper, we discuss possibilities of using red algae as biomarkers of marine pollution, and as bio filters in the processes of water natural.
Biochemical Alternation In Fresh Water Fishe Labeo Rohita Exposed To The Sodi...iosrjce
Fishes are regarded as an important high grade protein containing food staple of Indian people.
Ever increasing water pollution level, especially sodium fluoride (NaF), in inland freshwater reservoir has
made significant biochemical changes in the life cycle of fishes. In view of this, the investigations on effects of
acute and chronic sodium fluoride toxicity to fish Labeo rohita have been carried out. The changes in glycogen,
protein and lipid content of selected tissues like muscle, liver, gill and kidney were examined. The study
revealed a highest loss of glycogen, protein and lipid percentage in all tissues as compared to control.
combined toxicity and bioconcentration of fluoride and arsenic in african (3)IJEAB
Laboratory experiments were performed to examine the combined toxic effects of two important aquatic contaminants viz., arsenic and fluoride on African catfish, Clarias gariepinus. Additionally, the bio concentration factors (BCFs) of the two contaminants in tissues and blood of catfish were also determined. The LC50 for sodium fluoride and arsenic trioxide were determined to be 619.3 mg L-1, 30.3 mg L-1, respectively. Erratic swimming movements with hyperactivity, loss of equilibrium, augmented air gulping and decreased food consumption were observed in the experimental groups. In co-exposure groups of arsenic and fluoride, the concentration of fluoride in fish tissues increased with increasing water fluoride concentration in the test aquaria with significant differences (P<0.01)><0.05)>0.05) among the exposure groups. Arsenic was observed to exceedingly bioaccumulate and biomagnify in the tissues. Perhaps due to the complex formation of arsenic and fluoride the bio concentration of arsenic in tissues was observed to decrease with increasing water fluoride concentration and vice-versa. The study concludes that fluoride may interfere with the bio-concentration of arsenic.
Chemical communications among plant and animal components are fundamental elements for the functioning and the connectivity of ecosystems. In particular, wound-activated infochemicals trigger specific reactions of invertebrates according to evolutionary constraints, permitting them to identify prey cues, escape predators and optimize their behaviors according to specific life strategies.
Acute Toxicity and Bioaccumulation Patterns of Lead and Zinc in Juveniles of ...iosrjce
Acute toxicity of lead and zinc salts (Pb(NO3)2 and ZnCl2) and their bioaccumulation patterns in
juveniles of Clarias gariepinus was investigated. ZnCl2 with a 96hr LC50 value of 15.301mg/l was found to be
more toxic than Pb(NO3)2 with a 96hr LC50 value of 51.516mg/l. ZnCl2 was bio-accumulated at a faster rate
in the gills and flesh of the fish than Pb(NO3)2 . The amount of ZnCl2 and Pb(NO3)2 bio-accumulated reduced
as the experiment proceeded. Higher levels of ZnCl2 were recorded in the gills than in the flesh of the juvenile
fishes. Essential heavy metals can be more toxic to aquatic organisms than non essential heavy metals when the
former is present in high enough concentrations. Water chemistry, speciation and bio-availability of heavy
metals in surrounding media are major factors that determine rate of accumulation in aquatic organisms.
Studying the expression of proteins in Chrysichthys nigrodigitatus muscle, is essential to understand the biological, physiological and ecological aspects that may be of advantage in ecotoxicology as a tool for biomonitoring the effects of environmental pollution, as well as food safety. This study was aimed to accomplish a systematic characterization of the muscle proteome as well as to identify a putative set of protein biomarkers in C. nigrodigitatus to environmental pollution in Ologe and Badagry lagoons. Fifteen fi sh samples were used
as representative of the population for proteomics analysis. 116 proteins was expressed with 70 up-regulated, 25 down-regulated from Ologe Lagoon and 30 up-regulated, 17 down-regulated proteins from Badagry Lagoon expressed in the muscle of C. nigrodigitatus in response to environmental stressors using iTRAQ, while 8 protein spots from 2-D gels, representing 8 proteins with 2 up-regulated and 6 down-regulated, have been identifi ed using MALDI TOF/TOF MS. Pearson correlation revealed signifi cant correlation (p < 0.05) betwee environmental variables and protein markers. The investigation revealed that the expressed proteins in the muscle of C. nigrodigitatus served as a prognostic tool to assess the fi sh health and pollution status, which was observed that the fi sh were physiologically perturbed by environmental stressors in Ologe and Badagry lagoons.
Evaluation of water quality and toxicityafter exposure of lead nitrate in Cy...Sana_haroon
This presentation is made on the research paper "Evaluation of water quality and toxicityafter exposure of lead nitrate in Cyprinus carpio"
which is written by Paul et., al 2019
Hepatoprotective and antioxidant effects of Azolla microphylla based gold nan...Nanomedicine Journal (NMJ)
Abstract
Objective(s):
Our present study sought to evaluate hepatoprotective and antioxidant effects of methanol extract of Azolla microphylla phytochemically synthesized gold nanoparticles (GNaP) in acetaminophen (APAP) - induced hepatotoxicity of fresh water common carp fish.
Materials and Methods:
GNaP were prepared by green synthesis method using methanol extract of Azolla microphylla. Twenty four fishes weighing 146 ± 2.5 g were used in this experiment and these were divided into four experimental groups, each comprising 6 fishes. Group 1 served as control. Group 2 fishes were exposed to APAP (500 mg/kg) for 24 h. Groups 3 and 4 fishes were exposed to APAP (500 mg/kg) + GNaP (2.5 mg/kg) and GNaP (2.5 mg/kg) for 24 h, respectively. The hepatoprotective and antioxidant potentials were assessed by measuring liver damage, biochemical parameters, ions status, and histological alterations.
Results:
APAP exposed fish showed significant elevated levels of metabolic enzymes (LDH, G6PDH and MDH), hepatotoxic markers (GPT, GOT and ALP), reduced hepatic glycogen, lipids, protein, albumin, globulin, increased levels of bilirubin, creatinine, and oxidative stress markers (TBRAS, LHP and protein carbonyl), altered the tissue enzymes (SOD, CAT, GSH-Px and GST) non-enzyme (GSH), cellular sulfhydryl (T-SH, P-SH and NP-SH) levels, reduced hepatic ions (Ca2+, Na+ and K+), and abnormal liver histology. It was observe that GNaP has reversal effects on the levels of above mentioned parameters in APAP hepatotoxicity.
Conclusion:
Azolla microphylla phytochemically synthesized GNaP protects liver against oxidative damage and tissue damaging enzyme activities and could be used as an effective protector against acetaminophen-induced hepatic damage in fresh water common carp fish.
Impact of Imidacloprid 17.8 SI on Biochemical Parameters of the Fresh Water F...ijtsrd
Use of pesticide in integrated farming in paddy field is recognized as a potential threat in aquatic organisms. The effect of sublethal toxicity of imidacloprid 17.8 SL pesticide on some biochemical parameters of a freshwater fish Catla catla were studied after 24 hr, 48 hr, 72 hr and 96 hr of exposure. The lethal concentration LC50 of imidacloprid 17.8 SL for 96 hr was 4.11 ppm. The study suggests that exposure to imidacloprid 17.8 SL at low concentration results in significant biochemical alterations. The biochemical response of C. catla to the exposure to sub lethal concentrations of imidacloprid 17.8 SL showed a significant decrease p 0.001 of proteins and glycogen in muscle and liver tissues compared to the control group. The observations from the present study showed that, imidacloprid 17.8 SL altered the biochemical composition of the various organs of test fish, due to utilization of biochemical energy to counteract the toxic stress. Sumaiya Ismayil | Aneykutty Joseph "Impact of Imidacloprid 17.8% SI on Biochemical Parameters of the Fresh Water Fish Catla Catla" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-4 | Issue-4 , June 2020, URL: https://www.ijtsrd.com/papers/ijtsrd31088.pdf Paper Url :https://www.ijtsrd.com/biological-science/zoology/31088/impact-of-imidacloprid-178-si-on-biochemical-parameters-of-the-fresh-water-fish-catla-catla/sumaiya-ismayil
New Spectrophotometric Determination of Tenofovir Disoproxil Fumaratein Bulk ...IOSRJAC
Two new, selective and sensitive visible spectrophotometric methods (method A and B) have been developed for the estimation of Tenofovir disoproxil fumaratein bulk and in pharmaceutical preparations. Method ‘A’ is based on the reaction with wool fast blue, in the presence of buffer at PH 1.5 to form a colored species with a λmax 590nm. Method B is based on the reaction with tropaeoline -00 dye under acidic condition with a λ max 410nm. Beer’s law is obeyed in the concentration range of 50 to 250µg/ml for both the methods. The methods were extended to pharmaceutical formulations and there was no interference form any common pharmaceutical excepients and diluents. The result of analysis has been validated statistically and by recovery studies.
Heavy Metals in organs and endoparasites of Oreochromisniloticus, Sediment an...iosrjce
IOSR Journal of Environmental Science, Toxicology and Food Technology (IOSR-JESTFT) multidisciplinary peer-reviewed Journal with reputable academics and experts as board member. IOSR-JESTFT is designed for the prompt publication of peer-reviewed articles in all areas of subject. The journal articles will be accessed freely online.
ABSTRACT- Aquatic organisms have been considered to concentrate metals several times greater than environmental levels. Fishes have been used for many decades to evaluate the pollution status of water and thus considered as excellent biological indicator of heavy metals in aquatic environments. Heavy metals are natural tress components of the aquatic environment, but their levels have increased due to domestic, industrial, mining and agricultural activities. These heavy metals when accumulated in the fish tissues, they damage and weaken the mechanisms concerned leading to physiological, pathological and biochemical changes. The lead is non essential element while cobalt is an essential element for living organisms but its presence in fresh water in higher concentration are toxic to organism’s brain, liver, ovary, kidney and gills of the fish. The present study was aimed to investigate the changes due to two heavy metals (lead & cobalt) on the activity of the antioxidant enzyme, Catalase (CAT), Reduced glutathione (GSH), and Lipid peroxidation (LPO) in the brain of Danio rerio during 5, 10, 15 and 20 days of exposure period. For this study adult fishes were exposed to four different concentrations viz., 20, 30, 40 and 50 mg/l of cobalt and 5, 9, 13, and 17 mg/l of lead. Key-words- Zebrafish, Lead, Cobalt, Catalase, LPO, Glutathione, Heavy metals
— The formation, species composition and functional role of red algae were studied in the Black Sea's coastal zone. In sublittoral plant communities, red algae are dominant both by their number of species in the phytocenosis and by their active thallus-the one that ensures their high metabolism. Algae with a large specific surface area of thallus can accumulate heavy metals in higher concentrations. In the paper, we discuss possibilities of using red algae as biomarkers of marine pollution, and as bio filters in the processes of water natural.
Biochemical Alternation In Fresh Water Fishe Labeo Rohita Exposed To The Sodi...iosrjce
Fishes are regarded as an important high grade protein containing food staple of Indian people.
Ever increasing water pollution level, especially sodium fluoride (NaF), in inland freshwater reservoir has
made significant biochemical changes in the life cycle of fishes. In view of this, the investigations on effects of
acute and chronic sodium fluoride toxicity to fish Labeo rohita have been carried out. The changes in glycogen,
protein and lipid content of selected tissues like muscle, liver, gill and kidney were examined. The study
revealed a highest loss of glycogen, protein and lipid percentage in all tissues as compared to control.
combined toxicity and bioconcentration of fluoride and arsenic in african (3)IJEAB
Laboratory experiments were performed to examine the combined toxic effects of two important aquatic contaminants viz., arsenic and fluoride on African catfish, Clarias gariepinus. Additionally, the bio concentration factors (BCFs) of the two contaminants in tissues and blood of catfish were also determined. The LC50 for sodium fluoride and arsenic trioxide were determined to be 619.3 mg L-1, 30.3 mg L-1, respectively. Erratic swimming movements with hyperactivity, loss of equilibrium, augmented air gulping and decreased food consumption were observed in the experimental groups. In co-exposure groups of arsenic and fluoride, the concentration of fluoride in fish tissues increased with increasing water fluoride concentration in the test aquaria with significant differences (P<0.01)><0.05)>0.05) among the exposure groups. Arsenic was observed to exceedingly bioaccumulate and biomagnify in the tissues. Perhaps due to the complex formation of arsenic and fluoride the bio concentration of arsenic in tissues was observed to decrease with increasing water fluoride concentration and vice-versa. The study concludes that fluoride may interfere with the bio-concentration of arsenic.
Chemical communications among plant and animal components are fundamental elements for the functioning and the connectivity of ecosystems. In particular, wound-activated infochemicals trigger specific reactions of invertebrates according to evolutionary constraints, permitting them to identify prey cues, escape predators and optimize their behaviors according to specific life strategies.
Acute Toxicity and Bioaccumulation Patterns of Lead and Zinc in Juveniles of ...iosrjce
Acute toxicity of lead and zinc salts (Pb(NO3)2 and ZnCl2) and their bioaccumulation patterns in
juveniles of Clarias gariepinus was investigated. ZnCl2 with a 96hr LC50 value of 15.301mg/l was found to be
more toxic than Pb(NO3)2 with a 96hr LC50 value of 51.516mg/l. ZnCl2 was bio-accumulated at a faster rate
in the gills and flesh of the fish than Pb(NO3)2 . The amount of ZnCl2 and Pb(NO3)2 bio-accumulated reduced
as the experiment proceeded. Higher levels of ZnCl2 were recorded in the gills than in the flesh of the juvenile
fishes. Essential heavy metals can be more toxic to aquatic organisms than non essential heavy metals when the
former is present in high enough concentrations. Water chemistry, speciation and bio-availability of heavy
metals in surrounding media are major factors that determine rate of accumulation in aquatic organisms.
Studying the expression of proteins in Chrysichthys nigrodigitatus muscle, is essential to understand the biological, physiological and ecological aspects that may be of advantage in ecotoxicology as a tool for biomonitoring the effects of environmental pollution, as well as food safety. This study was aimed to accomplish a systematic characterization of the muscle proteome as well as to identify a putative set of protein biomarkers in C. nigrodigitatus to environmental pollution in Ologe and Badagry lagoons. Fifteen fi sh samples were used
as representative of the population for proteomics analysis. 116 proteins was expressed with 70 up-regulated, 25 down-regulated from Ologe Lagoon and 30 up-regulated, 17 down-regulated proteins from Badagry Lagoon expressed in the muscle of C. nigrodigitatus in response to environmental stressors using iTRAQ, while 8 protein spots from 2-D gels, representing 8 proteins with 2 up-regulated and 6 down-regulated, have been identifi ed using MALDI TOF/TOF MS. Pearson correlation revealed signifi cant correlation (p < 0.05) betwee environmental variables and protein markers. The investigation revealed that the expressed proteins in the muscle of C. nigrodigitatus served as a prognostic tool to assess the fi sh health and pollution status, which was observed that the fi sh were physiologically perturbed by environmental stressors in Ologe and Badagry lagoons.
Evaluation of water quality and toxicityafter exposure of lead nitrate in Cy...Sana_haroon
This presentation is made on the research paper "Evaluation of water quality and toxicityafter exposure of lead nitrate in Cyprinus carpio"
which is written by Paul et., al 2019
Hepatoprotective and antioxidant effects of Azolla microphylla based gold nan...Nanomedicine Journal (NMJ)
Abstract
Objective(s):
Our present study sought to evaluate hepatoprotective and antioxidant effects of methanol extract of Azolla microphylla phytochemically synthesized gold nanoparticles (GNaP) in acetaminophen (APAP) - induced hepatotoxicity of fresh water common carp fish.
Materials and Methods:
GNaP were prepared by green synthesis method using methanol extract of Azolla microphylla. Twenty four fishes weighing 146 ± 2.5 g were used in this experiment and these were divided into four experimental groups, each comprising 6 fishes. Group 1 served as control. Group 2 fishes were exposed to APAP (500 mg/kg) for 24 h. Groups 3 and 4 fishes were exposed to APAP (500 mg/kg) + GNaP (2.5 mg/kg) and GNaP (2.5 mg/kg) for 24 h, respectively. The hepatoprotective and antioxidant potentials were assessed by measuring liver damage, biochemical parameters, ions status, and histological alterations.
Results:
APAP exposed fish showed significant elevated levels of metabolic enzymes (LDH, G6PDH and MDH), hepatotoxic markers (GPT, GOT and ALP), reduced hepatic glycogen, lipids, protein, albumin, globulin, increased levels of bilirubin, creatinine, and oxidative stress markers (TBRAS, LHP and protein carbonyl), altered the tissue enzymes (SOD, CAT, GSH-Px and GST) non-enzyme (GSH), cellular sulfhydryl (T-SH, P-SH and NP-SH) levels, reduced hepatic ions (Ca2+, Na+ and K+), and abnormal liver histology. It was observe that GNaP has reversal effects on the levels of above mentioned parameters in APAP hepatotoxicity.
Conclusion:
Azolla microphylla phytochemically synthesized GNaP protects liver against oxidative damage and tissue damaging enzyme activities and could be used as an effective protector against acetaminophen-induced hepatic damage in fresh water common carp fish.
Impact of Imidacloprid 17.8 SI on Biochemical Parameters of the Fresh Water F...ijtsrd
Use of pesticide in integrated farming in paddy field is recognized as a potential threat in aquatic organisms. The effect of sublethal toxicity of imidacloprid 17.8 SL pesticide on some biochemical parameters of a freshwater fish Catla catla were studied after 24 hr, 48 hr, 72 hr and 96 hr of exposure. The lethal concentration LC50 of imidacloprid 17.8 SL for 96 hr was 4.11 ppm. The study suggests that exposure to imidacloprid 17.8 SL at low concentration results in significant biochemical alterations. The biochemical response of C. catla to the exposure to sub lethal concentrations of imidacloprid 17.8 SL showed a significant decrease p 0.001 of proteins and glycogen in muscle and liver tissues compared to the control group. The observations from the present study showed that, imidacloprid 17.8 SL altered the biochemical composition of the various organs of test fish, due to utilization of biochemical energy to counteract the toxic stress. Sumaiya Ismayil | Aneykutty Joseph "Impact of Imidacloprid 17.8% SI on Biochemical Parameters of the Fresh Water Fish Catla Catla" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-4 | Issue-4 , June 2020, URL: https://www.ijtsrd.com/papers/ijtsrd31088.pdf Paper Url :https://www.ijtsrd.com/biological-science/zoology/31088/impact-of-imidacloprid-178-si-on-biochemical-parameters-of-the-fresh-water-fish-catla-catla/sumaiya-ismayil
if your doing fish dissection and need some anatomical information then go through my slides.
in this i have written fish anatomy with its physiological implications
Effects of Fenitrothion on some histo-architecture of freshwater fish Channa ...IOSR Journals
The presence of insecticide in the environment, due to extensive use in agriculture is of potential toxicological concern for fish. Histotoxicological studies have been widely used as biomarkes in the evaluation of the health of fish exposed to the pesticides studies. In the present study the hazardous effect of the organophosphate insecticide, Fenitrothion on the histology of the fresh water fish (Channa punctatus) after exposure for 21 days was investigated. Fish used in the experiment was nearly similar weight and length. The treated groups were compared with the control group for the histological changes in the selected tissue (kidney, liver and heart) and marked changes were observed.
IOSR Journal of Pharmacy and Biological Sciences(IOSR-JPBS) is an open access international journal that provides rapid publication (within a month) of articles in all areas of Pharmacy and Biological Science. The journal welcomes publications of high quality papers on theoretical developments and practical applications in Pharmacy and Biological Science. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
IOSR Journal of Pharmacy (IOSRPHR), www.iosrphr.org, call for paper, research...iosrphr_editor
IOSR Journal of Pharmacy (IOSRPHR), www.iosrphr.org, call for paper, research paper publishing, where to publish research paper, journal publishing, how to publish research paper, Call for research paper, international journal, publishing a paper, call for paper 2012, journal of pharmacy, how to get a research paper published, publishing a paper, publishing of journal, research and review articles, Pharmacy journal, International Journal of Pharmacy, hard copy of journal, hard copy of certificates, online Submission, where to publish research paper, journal publishing, international journal, publishing a paper
DEVELOPMENT OF MATHEMATICAL MODEL TO PREDICT THE TRANSPORT OF E.COLI IN A NAT...IAEME Publication
Development of mathematical model to predict the rate of microbial depositions (E.coli) in a natural pond has been carried out. The models were developed to monitor the rate of concentration at different periods, with respect to the length of the pond at various sample station. Results of the theoretical values were compared with the experimental analysis. The analysis was thoroughly done to determine the physiochemical parameters of the pond. Microbial traces were found from the experimental analysis at different periods up to hundred days. The developed model compared favourably well with the experimental values. The values explain the rate of microbial growth and level of lag phase condition. The growth rate of the microbes were found to be higher because there is high deposition of substrate for growth and energy, while at some periods it degrades showing that the substrates have reduced in concentration including the inhibition from the pH. In some cases when the microbes developed lag phase condition it may be as a result of other environmental factors. Finally, the growth rates are between fifty and hundred days, showing that there is constant regeneration of the microbes including other environmental factors.
Changes in the Hematology Parameters of Freshwater Fish Channa striatus Expos...BRNSS Publication Hub
In the present study was sublethal concentrations of propargite pesticide administered to freshwater fish C. striatus for 96 hours propargite exposure is 0.34 parts per million (ppm) based on the period of (0.034ppm), (1.02ppm), 15 and 30 days about significantly (P > 0.05) in hematological parameters alterations was recorded. The hematological analysis showed significant (P > 0.05) reduction in red blood cell count, hemoglobin value, packed cell volume, mean corpuscular hemoglobin (MCH), MCH concentration, and mean corpuscular volume. The parameters such as total white blood cells increased when induced toxic content. The present study indicated marked changes in the blood of C. striatus after exposure to propargite pesticide.
One of the six lectures composing 'Exploring Ocean, Explore the Planet Earth' online course offered by Blue Green Foundation Bangladesh & Octophin. The training was attended by participants from 40 countries. The presentation is organized in three sections: (i) the good- describing what benefits we get from the Ocean, (ii) the bad- bad things happening to the ocean because of human activities, e.g. climate change and their impacts on the sea, (iii) the ugly- very bad things that are happening to the sea due to anthropogenic activities, pollution and their impacts on ocean life forms are discussed in this section.
DOI: 10.21276/ijlssr.2016.2.3.13
ABSTRACT- The present investigation was carried out to the effect of Fenvalerate on haematological parameters in
freshwater fish Channa marulius using standard methods. Fish was exposed to (1/4th LC50) sub lethal concentration of
Fenvalerate (0.086ppm) for 96h.The blood sample were obtained from both, control and experimental fish and assayed
haematological parameters (Total Erythrocytes count, TEC; Total Leucocytes count, TLC; Haemoglobin, Hb; Packed cell
volume, PCV; Mean corpuscular volume, MCV; Mean Corpuscular Haemoglobin and Mean Corpuscular Haemoglobin
Concentration; MCHC). The result revealed that TEC, Hb percentage, PCV and MCHC counts were significantly
decreased, whereas TLC, MCV and MCH increased slightly in experimental fish. The study has thus indicated marked
changes in blood of Channa marulius after exposure to Fenvalerate.
Key-words- Fenvalerate, Hematology, Channa marulius, Haemoglobin, Sub lethal
Environmental conditions and zooplankton community structure in five ponds in...Innspub Net
The degradation of surface water quality in Cameroon is linked to the absence of a functional waste management strategy. For such a strategy to be efficient, a general understanding of aquatic ecosystems will be of importance, these management strategies are particularly lacking in the eastern part of the country. To better understand and appreciate the ecosystems in the town of Bertoua, five ponds where chosen for the physicochemical and zooplankton communities analysis. Sampling on these ponds was conducted from March 2016 to April 2017 on a monthly basis. Samples for physicochemical analysis were collected at 20cm below water surface at the middle of each pond and measured were done following the recommendations of Rodier and Alpha. Biological samples were collected by filtering 50 liters of water through a 64µm mesh opening sieve. Identification was done using standard methods and identification keys. One-way ANOVA analysis was conducted to assess the potential differences between the different ponds base monthly observations. Although they are all hypereutrophic, with regard to the values of the physicochemical parameters, the five ponds showed no significant difference between them but, the structure of the zooplankton community remains very diverse. 118 zooplankton species have been identified in the five ponds. The distribution of zooplankton in these hydrosystems was mainly governed by the presence of organic matter. This study sheds light on the status and biological diversity of ponds in eastern Cameroon, data on which to rely to develop management strategies.
ABSTRACT- The present study was conducted to investigate the effect of cadmium chloride on Histoarchiteceture of head kidney of fresh water fish Heteropneustes fossilis. The fishes were exposed to 0.5 ppm of cadmium chloride for 21 days. The most remarkable changes in head kidney, due to cadmium chloride were lysed condition of interrenal and chromaffin cells. The traces of cytoplasm had dark brown to black coloured cytoplasm. Most of cells are deformed and necrotic condition. Their size was significant at (P< 0.01 and 0.001) increased after cadmium chloride. All these changes will be recovered by herbal compound i.e. Ashwagandha. The damaged tissues were recovered in already treated group.
Key-words- Ashwagandha, Cadmium chloride, Chromaffin cells, Heteropneustes fossilis, Histopathology, Interrenal cells
Standard water quality requirements and management strategies for fish farmin...eSAT Journals
A study on standard water quality requirements and management strategies suitable for fish farming is presented. The water quality criteria studied based on physical, chemical and biological properties of water include temperature, turbidity, total suspended solids (TSS), total dissolved solid (TDS), nitrate- nitrogen, pH, biochemical oxygen demand (BOD) and total hardness. Water samples from Otamiri River in Imo state, Nigeria, were analyzed based on the afore-mentioned criteria to assess its suitability as a source of water for fish farming. The results of the analysis compared with international standards revealed that the river temperature of 26.90C, nitrate-nitrogen value of 0.015 mg/l and total suspended solids of 18.60 mg/l fall within the acceptable range for fish farming. However, the pH of 5.82, total hardness of 5.8 mg/l, total dissolved solids of 13.60 mg/l and biochemical oxygen demand of 0.6 mg/l all differed slightly from the standard recommended values. This study will aid fish farmers on the necessary treatment needed to effectively use water from this source for fish farming.
Keywords: Water quality criteria, Otamiri River, biochemical oxygen demand, total suspended and total dissolved solids.
E-screen assay validation: evaluation of estrogenic activity by MCF7 cell cul...Agriculture Journal IJOEAR
— Natural and synthetic estrogens have been detected in rivers, lakes and estuaries in many parts of the world. Primary sources of these compounds are domestic and industrial effluents, which are not deleted after the water treatment. Estrogen has been the endocrine disruptor most researched to be very active biologically and be the etiologic agent of diverse types of cancer and other conditions such as endometriosis, precocious puberty, feminization, masculinization, sterility. In this context, we use water of 36 natural reservoirs or dams, in a bioassay to characterize their estrogenicity in culture of MCF7 cells and obtained high concentration of estrogen in samples taken in Ibiúna and Equestrian Santo Amaro / SP. However, certain concentration in our samples for most water samples from different regions was very close to the limit of quantification by bioassay and estrogen was in fmol. It has been shown that e-screen assay with MCF7 cells is a sensitive and stable tool for quantitative analysis of estrogenicity of water and can easily be developed and implemented for routine for estrogen quantification also in animal food and man, aqueous and plastics etc. Keywords— endocrine disrupters, estrogen, breast cancer cells, (MCF7) bioassay: E-screen assay
Lead Acetate Induced histopathological Changes in Kidney Tissue of RatIOSRJAVS
One of the pollutants that can effect on the life of living animates is lead in different ways; it has toxic problem for human and animals and is gathered in the tissues and guide to harmful effects in their. The current study was carry out to investigate the histological effects caused by lead in the rat. The study was performed on 30 rat, they were divided into 3 groups. The first group was control group that received distilled water. The second groups were orally administered lead acetate 9 mg/l of body weight for 10 days. The third groups were orally administered solution of lead. The rats were anesthetized, the kidney were removed for histological studies. Histological changes which observed in the kidney were fatty degeneration, destruction tubules, and congestion within connective tissue, hemorrhage and infiltration of inflammatory cells. In this study, harmful toxic effects observed in kidney of rats.
Similar to Histopathological Impact of Dimethoate on the Kidney of Freshwater Fish, Garra mullya (Sykes) (20)
Background: Cancer is a disease caused when cells divide uncontrollably and spread into the surrounding tissue. Changes to DNA cause cancer. It is one of the most common and largest killer diseases in the world. It usually affects physically, and the disease can alter one’s perspective on life and personality. Many treatment options are there to treat cancer. Among them, chemotherapy treatment may have more side effects like lethargy, esophagitis, nausea, vomiting, Fatigue, and insomnia, the most common problems among chemotherapy patients in India. Methods: A quasi-experimental study with a sample size of 60, out of which 30 subjects were in the experimental group and 30 were in the control group. A convenient sampling method was used to select the subjects. A structured questionnaire tool was used to collect the data. Result: The result of the study showed that, during pre-test in the study group, among 30 subjects 3(10%) had moderate Fatigue, 22(73.33%) had severe Fatigue, 5(16.67%) had worst Fatigue and 12(40%) had moderate insomnia, 18(60%) had severe insomnia and in control group among 30 subjects, 6(20%) had moderate Fatigue, 13(43.33%) had severe Fatigue, 11(36.67%) had a worst fatigue, and 14(46.67%) had moderate insomnia, 16(53.33%) had severe insomnia. With post-test, in experimental group, 14(46.67%) had no fatigue, 16(53.33%) had mild fatigue, 14(46.67%) had no insomnia, 16(53.33%) had mild insomnia, and in control group, 6(20%) had moderate fatigue, 13(43.33%) had extreme fatigue, 11(36.67%) had worst fatigue, and 14(46.67%) had moderate insomnia, 16(53.33%) had severe insomnia. Conclusion: The study concluded that clients who were receiving chemotherapy had fatigue and insomnia problems. The Warm water foot bath therapy is very effective in clients undergoing chemotherapy in reducing Fatigue and insomnia. A positive correlation between pre-test and post-test was found by using the Mann-Whitney test.
Key-words: Cancer, Chemotherapy, Foot bath, Health, Warm water
Background: Alcohol has long been a global social and medical issue. According to W.H.O report. Total 3.3 million people die from
alcohol abuse annually. Alcoholic liver disease (A.L.D.) ranges from steatosis to liver cirrhosis. Chronic heavy drinkers get hepatitis
or cirrhosis 15 20% of the time
Methods: This study was c onducted in the general medicine inpatient department at PGIMER & C . in Bhubaneswar, Odisha,
Indi a. All hospitali z ed patients with liver illness who had previously t aken alcohol were screened. Each patient's alcohol
consumption, including native alcoholic beverages, was recorded. To support the diagnosis, all standard and extra examination s
were carri ed out. The modified Kuppuswamy scale was used to determine s s ocioeconomic class.
Results: The study comprised 186 participants with a median age of 46. The gender ratio was 3:1, with 139 (74.7%) men. Urban
populations have a greater prevalence of alcohol ic liver disease (60.75%) than rural populations (39.24%). The l ower
s ocioeconomic c lass (50.53%) has the highest rate of alcoholic liver disease. Men drink more (>700 gm/wk) and married people
drink more. A woman who drinks 140 280 grams per week for 10 1 5 years is more likely to develop alcoholic liver disease than a
man who drinks >700 grams per week for 15 years.
Conclusions: In this study, we conclude d that the prevalence of A .L. about S .E. is of utmost importance in developing
population based st r ategies that effectively educate individuals on the need to modify their drinking habits. This is crucial to
mitigate the occurrence of alcohol consumption and its associated repercussions.
Key-words: Socioeconomic status, Hospitalized Patients, Alcoholic Liver Disease
Background: One of the most common disorders in this age group, abnormal uterine bleeding (AUB), is the primary cause of most gynaecological problems in adolescents. Unfortunately, epidemiological data on AUB in teenagers is scarce, especially in the Indian subcontinent. The PALM-COEIN classification, where PALM stands for structural reasons and COEIN for functional causes, was employed in this single-center prospective observational study to evaluate the relative contributions of several etiological factors in AUB. To comprehend the etiological, dermographic, and therapeutic factors affecting menorrhagia in patients going through adolescence. Methods: Enrollment for females with AUB between 10 and 19 occurred between January and December 2022. A thorough history, physical examination, and laboratory evaluation, which in every case comprised standard testing, hormone analysis, and abdominal and pelvic ultrasonography were used to determine the cause of AUB. MRIs and CT scans were performed when needed. Results: There were 190 patients enrolled in total. Functional factors comprised the predominant aetiology of AUB among adolescent females: Adenomyosis=01 (0.52%), Polyp=1 (0.52%). Coagulopathy=2 (1.05%), Leomyoma=01 (0.52%), Malignancy=1 (0.52%), and PALM=4 (2.11%). COEIN=186 (97.89%), ovulation disorder=175 (92.15%), endometrial=01 (0.52%), iatrogenic=6 (3.15%), non-specified=2 (1.05%), and iatrogenic=6 (3.15%). Conclusion: The most frequent cause of AUB in the adolescent population is ovulatory abnormalities. Even though they are extremely rare, structural factors must be ruled out. A helpful technique for evaluating patients with AUB systematically is the PALM-COEIN classification.
Key-words: PALM-COEIN, Leiomyoma, AUB, Polycystic ovarian syndrome, Hormonal therapy
Derived from the bacterium Proteus vulgaris , chondroitin ABC lyase is an enzyme that can be used in treating proteoglycans that
affect neural activity (communication, plasticity). Chondroitinase can be used for vision abnormalities and spinal injuries. The
biological activity of chondroitinase is due to its ability to act on chondroitin sulfate proteoglycans (CSPGs) which are required for
normal functioning. Th is study aim s to examine various types and routes of administration of Chondr oitina se e n zymes. There is an
increasing application of chondro itin sulfate proteoglycans in spinal cord injury, vit reous attachment, and the management of
various carcinogenic conditions. Research must be done to create an effective chondroitinase delivery mech anism so that the
pharmacological activity seen in vitro and in preclinical research may be applied in the clinic. More studies are required to widen
the application of chondroitinase in therapeutics. In this review, chondroitinase ABC, B, and C are all di scuss ed. T he routes of
administration like caudal or ros tral, intracerebroventricular, hydrogels, and intrath ecal have been detailed. The current review
article highlights the different medical uses for chondroitinase, drug delivery methods for the enzym e, and chondroitinase
dispersion across bacteria. In conclusion, this study can reduce the chance of edema by the intracerebroventric ular route.
However, it is not effective for people due to the gyrencephalic anatomy of brain
Key-words: Chondroitinase, Chondroitin, Chondroitin Sulfate Proteoglycans, Spinal Injuries, Ocular Abnormalities, Proteoglycans
Background: Maturing is a widespread peculiarity. Advanced age is not in itself a sickness however is an ordinary piece of human existence length. A guardian, like wise called a career, home wellbeing assistant or individual consideration assistant, is the individual answerable for furnishing their clients with day-to-day private consideration and help with exercises. Methods: Exploration approach: unmistakable methodology research plan: graphic study research plan. The setting of the review: provincial areas of Bagalkot region. Information assortment strategy: organized polls test. The example was chosen by an arbitrary inspecting procedure. The analyst arbitrarily chose Shirur town as a provincial setting and was chosen for enrolment of subjects. Results: The information score of guardians was 41.06%, with mean and SD of 12.32±3.925. These discoveries uncover those guardians had normal information for advanced-age medical conditions. The mentality score of guardians was 73.73%, with a mean and SD of 110.6±11.008. These discoveries uncovers that parental figures have concur capable demeanour in regards to the advanced age medical conditions. Conclusion: At last, a critical co-connection between the information and demeanour at 0.001 the discoveries uncovers that there is a moderate positive relationship between the information and disposition of the advanced age medical issues.
Key-words: Assess, Care Giver, Health Problems, Knowledge, Old Age
Background: Adolescent is one of the most rapid phases of human development. Anemia is a deficiency in the number of RBC in your body. RBC carry oxygen around your body using a particular protein called hemoglobin. Normal hemoglobin level in adolescent girls 13-15 g/dl. According to WHO, the hemoglobin level 10- 11.9 g/dl is considered mild anemia, 7-9 g/dl is considered moderate, and less than 7 g/dl is called severe anemia. Methods: The present study is pre-experimental among 60 adolescent girls, using a disproportional stratified random technique. One experimental group of clients was selected without randomization and no control group was used. The data was collected by using the structured close-ended knowledge questionnaire. The data was analyzed using descriptive and inferential statistics regarding mean, frequency distribution, percentage, paired table t-test and chi-square test. Results: The overall findings reveal that the post-test knowledge mean score 26.24% with SD±5.94, which was 72% of the total score was more when compared to the pre-test knowledge mean score 12.98 with SD 5.94, which was 36.83% of total score. The calculated t-value of 24.91 was much higher than the table t-value 1.96 for the hypothesis. Conclusion: The study provides that VATP on knowledge regarding the preparation and use of moringa juice in managing anemia among adolescent girls was the scientific, logical and cost-effective strategy.
Key-words: Adolescent girls, Knowledge, VATP, Effectiveness, Socio-demographic variables.
Background: The research demonstrates that water birth comports and loosens mothers actually and intellectually. The buoyance lessens body weight and permits free development and situating to the mother. Buoyance and warm water upgrade uterine withdrawal and better blood flow, which builds uterine muscles' oxygenation, diminishes the mother's torment and increases maternal oxygenation of the child. Submersion of water assists with decreasing circulatory strain and additionally gives security, which hinders uneasiness or dread. Methods: The current review pre-trial study with 50, 4th-year B.Sc. Nursing is chosen through basic arbitrary methods. One gathering pre-test without control bunch configuration was utilized. Information was gathered through a self-directed, organized, shut, finished information survey. Data was examined by involving distinct and inferential measurements concerning mean rate by conveyance, matched "t" test, and Chi-square test for affiliation. Results: The pre-test reveals that out of 50 BSc 4th-year nursing students, the highest pre-test (62%) of BSc 4th-year nursing students had poor knowledge. Overall, the post-test knowledge score (22.6±4.19), 70.62% of the total score, was more than the pre-test knowledge score (8.76±3.95), 23.3%. The effectiveness of the assisted teaching programme, in this area, the mean knowledge score was 13.84 with SD±0.24, which was 43.25% of the total score. Hence, it indicates that the video-assisted teaching program effectively enhanced the knowledge of BSc 4th-year nursing students. Conclusion: This study concluded that video-assisted teaching programmes on knowledge regarding waterbirth among B.Sc 4th year Nursing students was the scientific, logical and cost-effective strategy.
Key-words: Effectiveness, Fourth year B.Sc. Nursing students, Knowledge, VATP, Water birth
Background: Post-menopausal women experience many physical, emotional, and mental symptoms during the post-menopausal period, and reflexology has grown into a complex therapeutic modality and has a range of effects. Reflexology will help put hormones back into a normal state and act like a process of emotional cleansing, relieving stress and restoring harmony to the body and soul. Hence, foot reflexology seems to be effective in treating post-menopausal symptoms. Methods: In the present study, pre-experimental i.e. one group pretest-posttest design, was adopted. The study was conducted on 30 post-menopausal women to assess their knowledge regarding foot reflexology. Samples were selected by using a convenient sampling technique. Data was collected using a structured knowledge questionnaire and analyzed using descriptive and inferential statistics. Results: The mean percentage of the pre-test score was 28%, and the post-test score was 76.65%. The mean and the standard deviation of the pre-test score were 5.60±1.71, and the mean and the standard deviation of the post-test score were 15.33±1.15. The total mean and standard deviation are 9.73±2.07 by comparing the pre-test and post-test scores. Hence, it was found that there is a significant difference between pre-test and post-test knowledge scores of post-menopausal women regarding foot reflexology. No significant association was found between post-test knowledge scores and socio-demographic variables on foot reflexology. Conclusion: The study concluded that a planned teaching program on knowledge regarding foot reflexology for post-menopausal women was a scientific, logical, and cost-effective strategy to reduce post-menopausal symptoms.
Key-words: Effectiveness, Foot reflexology, Post-menopausal women, Planned teaching program, Socio-demographic variables
Background: A 51-year-old woman had left lower abdomen pain for 18 hours with nausea and vomiting. Prior CT scans suggested pelvic neoplasms. Our hospital's emergency CT showed an enlarged uterus with cystic shadows, right adnexal cysts, and stomach fluid. Physical examination revealed left lower abdomen discomfort. A gynaecological examination revealed a painful, firm pelvic mass of 151210 cm. Further diagnosis is underway. Method: The patient underwent emergency exploratory laparotomy, discovering a twisted, swollen left ovary with a 540° rotation, classified as a benign cyst. It was found that the patient had congenital upper vaginal atresia and bilateral initial uteri. Pain was reduced after surgery, thanks to symptomatic treatment. An abnormal karyotype of 46, XX,1qh+ was found during genetic testing. Result: Fallopian tubes, uterus, and vagina develop from the embryonic accessory mesonephric duct. MRKH syndrome is caused by bilateral accessory mesonephric duct dysplasia and disappearance of the uterus or vagina. MRKH has three types, with Type 1 lacking uterus or vagina. Due to ovarian cyst torsion, this Type 1 MRKH with double initial uterus and upper vaginal atresia needed left adnexa resection. Genetic testing showed a typical female karyotype. MRKH's complex aetiology incorporates chromosomal abnormalities, emphasizing early cytogenetic evaluation for personalized treatment and fertility assistance. Conclusion: Early cytogenetic testing for MRKH syndrome patients is crucial for determining the underlying cause and guiding personalized treatment plans to restore reproductive function and improve quality of life.
Key-words: Double primordial uterus; MRKH syndrome; Upper vaginal atresia; Torsion of left ovarian cyst pedicle
Background: Cell phones have advanced to the degree of becoming a necessary piece of individuals' lives. Cell phones are utilised for correspondence, diversion, efficiency, interpersonal interaction, and gaming. In addition to supplanting the conventional cells, cell phones have likewise supplanted personal computers and numerous other comparative gadgets. Individuals these days feel indistinguishable from their cell phones. In lined with the rising improvement of innovation and excessive utilisation of cell phones, one of the significant issues that scientists have noticed and are chipping away at is cell phone addiction. Methods: It was a graphic study directed among 100 nursing students aged 19-22 in B.V.V.S. Institute of Nursing Sciences Bagalkot. Information was gathered utilising a structured knowledge questionnaire to survey socio-demographic information. The Stanford Sleepiness Scale (Alertness Test) was utilised to evaluate the classroom alertness of the nursing students and the Cell phone Addiction Scale-Short Version (SAS-SV) was utilised to assess the cell addiction of the nursing students. Results: An association was found between the year of studying and the classroom alertness of students (χ2 =3.9102) p<0.05. There was a significant negative correlation between cell phone addiction and classroom alertness of the nursing students, p<0.05. The r-value obtained was 0.80. Thus, the correlation between the two factors is seen as statistically significant. Conclusion In the wake of acquiring the consequences of the current work the scientist s saw a negati ve relationship between cell
pho ne addiction and the class room alertness of the students.
Key-words: Addiction, Alertness, Cell phone, Classroom, Phone addiction
Background: Chemical changes occur in the epididymis when the testicular sperm grows. When sperm and seminal fluids mix during ejaculation, a substance called semen is formed. The cervical mucus of a fertilized egg screens out the best possible sperm. For infertility, Intra Cytoplasmic Sperm Injection (ICSI) can be necessary. Test sperm that are DNA efficient, normal, and motile using Swim Up. Sperm could be damaged by reactive oxygen species that are produced during centrifugation. All infertility treatments should take these factors into account. Methods: The in vitro fertilization (ICSI) procedure was administered to fifty male patients who were 35 years old or younger and tested positive for normozoospermia, asthenozoospermia, and oligozoospermia. After obtaining informed consent, a Swim-Up was performed using both the full semen and a washed pellet. With sperm obtained from both methods, six Metaphase-2 stages of oocytes (MII oocytes) were implanted in each patient. A Tri-gas Bench-top incubator was used to put each injected oocyte in its 37°C setting. Results: The study showed that the age differences were insignificant (p=0.722), but significant variations emerged in sperm concentration before processing (p=1.030) and after (p=1.064). Sperm morphology differences were evident before processing (p=0.004) and after (p=0.002). No significant differences were noted in the number of Day 3 cleavage stage embryos. Conclusion: The study concluded that there is no significant difference between the two techniques regarding sperm washing efficiency.
Key-words: Sperm preparation methods, Swim-up, Centrifugation, ICSI, Fertilization, Day 3 Embryo
Background: The third most common musculoskeletal symptom in orthopaedic clinical practice is a sore shoulder, which can cause significant morbidity. It has been reported that 7–27% of the general population has it, and 36–66% of overhead arm athletes have it. Pathophysiology includes functional, degenerative, and mechanical factors. Most shoulder pain is subacromial pain syndrome (SAPS), often known as ‘shoulder impingement syndrome’. Impingement hypothesis: shoulder joint structures mechanically clash. SAPS accounts for 36–48% of shoulder discomfort. Methods: This observational study was conducted in the Department of Orthopaedics, MKCG Medical College and Hospital, Berhampur, among Eastern Indian outpatients. The study included adult patients (ages 18–75) of both sexes who presented to MKCG Medical College and Hospital's OPD with shoulder pain from December 2020 to November 2022 and were diagnosed with Shoulder Impingement Syndrome (SIS). Thorough histories and clinical exams were done. The Department of Radiology, MKCG Medical College and Hospital, Berhampur, performed conventional shoulder MRIs on the selected participants. Results: Most cases and controls were Type-II (43.3%), followed by Type-I (28.3% and 30%, 29.2% of the total group). The study's least common acromial shape was type-IV, seen in 5% of cases and 10% of controls (7.5% of the sample). Fisher's exact test showed no significant connection between subacromial impingement and acromial shape (p=0.65). With a p-value of 0.045, cases had a significantly greater acromial width (8.12±2.16 mm) than controls (7.51±0.81 mm). Conclusion: Sub-acromial impingement was unrelated to acromion morphology. There was no correlation between acromial morphology and rotator cuff injuries.
Key-words: Shoulder Impingement Syndrome, Acromion Morphology, MRI
Impact of Acceptance and Mindfulness-Based Intervention as an Add-on Treatment for Skin Diseases-Acne, Eczema and Psoriasis
http://dx.doi.org/10.21276/SSR-IIJLS.2020.6.5.2
Seasonal Incidence and Varietal Response of Gram against Helicoverpa armigera (Hubner) at Talwandi Sabo, Punjab
http://dx.doi.org/10.21276/SSR-IIJLS.2020.6.4.3
More from SSR Institute of International Journal of Life Sciences (20)
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.