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KILLED VACCINES
Presented by
K.Balachander
18MIM07
Vaccine
The term vaccine is derived from the Latin word, vacca
(meaning cow), because cowpox was used to prevent
smallpox. Vaccination is the deliberate attempt to prevent
disease by “teaching” the immune system to employ
acquired immune mechanisms. In the 21st century, vaccines
are also being used to enhance existing immune
mechanisms with the development of vaccines as
treatments, so-called therapeutic vaccination.
History
The first vaccine was introduced by
British physician Edward Jenner,
who in 1796 used the
cowpox virus (vaccinia) to confer
protection against smallpox, a
related virus, in humans.
Killed / Inactivated Vaccine
• Inactivated vaccines are those that contain organisms that have
been killed or inactivated with heat or chemicals. Inactivated
vaccines elicit an immune response, but the response often is
less complete than with attenuated vaccines. Because
inactivated vaccines are not as effective at fighting infection as
those made from attenuated microorganisms, greater quantities
of inactivated vaccines are administered. Vaccines
against rabies, polio (the Salk vaccine), some forms
of influenza, and cholera are made from inactivated
microorganisms.
Adverse reactions associated with
inactivated whole-cell vaccines
Thank You…………

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Heat killed vaccine

  • 2. Vaccine The term vaccine is derived from the Latin word, vacca (meaning cow), because cowpox was used to prevent smallpox. Vaccination is the deliberate attempt to prevent disease by “teaching” the immune system to employ acquired immune mechanisms. In the 21st century, vaccines are also being used to enhance existing immune mechanisms with the development of vaccines as treatments, so-called therapeutic vaccination.
  • 3. History The first vaccine was introduced by British physician Edward Jenner, who in 1796 used the cowpox virus (vaccinia) to confer protection against smallpox, a related virus, in humans.
  • 4. Killed / Inactivated Vaccine • Inactivated vaccines are those that contain organisms that have been killed or inactivated with heat or chemicals. Inactivated vaccines elicit an immune response, but the response often is less complete than with attenuated vaccines. Because inactivated vaccines are not as effective at fighting infection as those made from attenuated microorganisms, greater quantities of inactivated vaccines are administered. Vaccines against rabies, polio (the Salk vaccine), some forms of influenza, and cholera are made from inactivated microorganisms.
  • 5.
  • 6. Adverse reactions associated with inactivated whole-cell vaccines