This document discusses the transition from Local Involvement Networks (LINks) to Local HealthWatch organizations and the role of HealthWatch England. Key points:
1) Local HealthWatch organizations will replace LINks and have an expanded role, including a seat on health and wellbeing boards to influence decisions.
2) HealthWatch England will be an independent consumer champion located within the Care Quality Commission to represent patients nationally and provide leadership to Local HealthWatch.
3) Pathfinder programs and action learning sets will help support the transition from LINks to Local HealthWatch and allow sharing of best practices.
Kate White, manager of Superhighways presented to the HWB meeting outlining how Superhighways will be managing the outcomes through its digital inclusion training programme
Kate White, manager of Superhighways presented to the HWB meeting outlining how Superhighways will be managing the outcomes through its digital inclusion training programme
Across England local Healthwatch are working to find out what people want from health and care services and to make sure that those who run services hear these views.
We’ve pulled together 28 stories from our 2016 Healthwatch Network Awards of how peoples views are helping to improve NHS and social care services across England.
This is the Plenary Presentation of CheyLeaphy Heng, Program Team Manager, Rainbow Community Kampuchea (RoCK) on the plenary topic: "UPR as an advocacy strategy for SOGIE-SC issues in Cambodia". This presentation was part of the 14th session of #APCRSHR10 Virtual, on the theme of "Sexual orientation and gender identity and SRHR in Asia Pacific".
Chair: Dr Chivorn Var, Convener of APCRSHR10 and Executive Director of Reproductive Health Association of Cambodia (RHAC)
Plenary Speaker: CheyLeaphy Heng, Program Team Manager, Rainbow Community Kampuchea (RoCK) | "UPR as an advocacy strategy for SOGIE-SC issues in Cambodia"
ABSTRACT PRESENTERS:
* Saroj Tamang | Male-to-Female Transgender Community barrier and challenges in access of Sexual Health Services
* Saritha P Viswan | A review of transgender issues in India
* Sobo Malik | Limited Access to Health Rights Resulting in Increase Self Medication
* Ciptasari Prabhawanti | Sexual Identity, Sexual Orientation, Sexual Risk and Condom Use Behaviors of Clients of Transgender Sex Workers in Jakarta, Indonesia
For further information, visit www.bit.ly/apcrshr10virtual14
Conference website: www.apcrshr10cambodia.org or check out www.bit.ly/apcrshr10virtual
Thanks
MRC/HIVAN KZN AIDS Forum - 30/10/12 - Challenges and Opportunities for HIV/AI...info4africa
This presentation was given on 30/10/12 at the MRC/HIVAN KZN AIDS Forum.
Co-presented by Kwazi Mbatha (CEGAA Researcher/Trainer) and Mlungisi Vila kasi (TAC Community Mobiliser - uMgungundlovu), this talk was facilitated by Judith King (CEGAA Communications and Advocacy Manager).
For more information on CEGAA please visit their website: http://www.cegaa.org/
Integrated data to support service redesign decision making 19 01 2016 finalNHS Improving Quality
Integrated data to support service redesign decision making
Leeds LTC Year of Care Commissioning Early Implementer Site
Tricia Cable, Year of Care Lead
Alison Phiri, Business Intelligence Manager
Mohini Chauhan, Year of Care Commissioning Manager
Read the final report of The Parliamentary Review about the future of health and social care in Wales. Parliamentary Review published a report which is produced in 12 months focused on the sustainability of health and social care in Wales.
https://gov.wales/topics/health/nhswales/review/?lang=en
An Innovative Management System Responds to the Needs of Tanzania's Most Vuln...JSI
APHA International Health Poster Session - HIV/AIDS
The Government of Tanzania is working to address a critical challenge faced by child protection and HIV practitioners: How to implement a systematic response that engages both community and facility based providers in a connected system to ensure most vulnerable children (MVC) and their families holistically receive social welfare, protection services, and HIV related needs.
The USAID Community Health and Social Welfare system Strengthening Program (CHSSP), implemented by JSI Research & Training Institute, Inc., collaborated with the Tanzania Department of Social Welfare to design, and finalize a National Integrated Case Management System (NICMS). This document sets forth a harmonized, standardized, and systematic structure for the care and protection of MVC and their families, with the goal of improving access to and integration of protection, social welfare, and health services, including HIV continuum of care. The NICMS is responsive to MVC needs including HIV-specific social issues and includes: strengthening bi-directional linkages and referrals between social welfare, Protection, and HIV clinical providers; Coordinating civil society organizations dealing with MVC; strengthening MVC committees and ensure supportive supervision at all levels. All components ultimately contribute towards expanding access to HIV care and treatment services, enhancing ART retention and adherence, improving referrals and linkages.
Recommendations/Conclusions: NICMS is a valuable initiative to serve MVC holistically, and has successfully integrated the Tanzanian health social welfare and Protection sectors to provide services across the continuum of care.
Learning Disabilities: Share and Learn Webinar – 27 April 2017NHS England
Creating a Dynamic Approach to Risk Stratification (including dynamic risk registers)
This webinar aims to share learning to help TCPs in developing a dynamic approach to risk stratification (which includes a developing dynamic risk register). The webinar provides the latest guidance from the national Transforming Care Programme and a real life example of how a TCP has approached the problem on the ground.
This webinar covers some of the same material as one run previously for North region TCPs on dynamic risk registers but also builds on that material with the latest guidance.
Strengthening Community Capacity for Effective Advocacy: A Strategy Developme...Humentum
Robert Musoke, PATH Uganda; Bernard Byagageire, PATH Uganda; Jennifer Gaberu, PATH Uganda. Presentation made during Humentum's Capacity for Humanity conference, February 2018.
Six principles for engaging people and communitiesJeremy Taylor
Slides presented at King's Fund on 1 November 2016. How to make real the vision in the Five Year Forward View of "a new relationship with patients and communities"? We know a lot about the "what" and the "who" of implementation. But the "how" is still a mess. What high impact actions would make a difference to driving this agenda? I offer some thoughts. These slides are not entirely self-explanatory without the accompanying talk. Please feel free to get in touch to explore further!
Session Two: Barriers to investment in research to find a disease modifying therapy or cure for dementia.
Dr. Luc Truyen, MD, PhD, VP Neuroscience External Affairs and Chair, Johnson&Johnson, Global Fight against !lzheimer’s Disease
Across England local Healthwatch are working to find out what people want from health and care services and to make sure that those who run services hear these views.
We’ve pulled together 28 stories from our 2016 Healthwatch Network Awards of how peoples views are helping to improve NHS and social care services across England.
This is the Plenary Presentation of CheyLeaphy Heng, Program Team Manager, Rainbow Community Kampuchea (RoCK) on the plenary topic: "UPR as an advocacy strategy for SOGIE-SC issues in Cambodia". This presentation was part of the 14th session of #APCRSHR10 Virtual, on the theme of "Sexual orientation and gender identity and SRHR in Asia Pacific".
Chair: Dr Chivorn Var, Convener of APCRSHR10 and Executive Director of Reproductive Health Association of Cambodia (RHAC)
Plenary Speaker: CheyLeaphy Heng, Program Team Manager, Rainbow Community Kampuchea (RoCK) | "UPR as an advocacy strategy for SOGIE-SC issues in Cambodia"
ABSTRACT PRESENTERS:
* Saroj Tamang | Male-to-Female Transgender Community barrier and challenges in access of Sexual Health Services
* Saritha P Viswan | A review of transgender issues in India
* Sobo Malik | Limited Access to Health Rights Resulting in Increase Self Medication
* Ciptasari Prabhawanti | Sexual Identity, Sexual Orientation, Sexual Risk and Condom Use Behaviors of Clients of Transgender Sex Workers in Jakarta, Indonesia
For further information, visit www.bit.ly/apcrshr10virtual14
Conference website: www.apcrshr10cambodia.org or check out www.bit.ly/apcrshr10virtual
Thanks
MRC/HIVAN KZN AIDS Forum - 30/10/12 - Challenges and Opportunities for HIV/AI...info4africa
This presentation was given on 30/10/12 at the MRC/HIVAN KZN AIDS Forum.
Co-presented by Kwazi Mbatha (CEGAA Researcher/Trainer) and Mlungisi Vila kasi (TAC Community Mobiliser - uMgungundlovu), this talk was facilitated by Judith King (CEGAA Communications and Advocacy Manager).
For more information on CEGAA please visit their website: http://www.cegaa.org/
Integrated data to support service redesign decision making 19 01 2016 finalNHS Improving Quality
Integrated data to support service redesign decision making
Leeds LTC Year of Care Commissioning Early Implementer Site
Tricia Cable, Year of Care Lead
Alison Phiri, Business Intelligence Manager
Mohini Chauhan, Year of Care Commissioning Manager
Read the final report of The Parliamentary Review about the future of health and social care in Wales. Parliamentary Review published a report which is produced in 12 months focused on the sustainability of health and social care in Wales.
https://gov.wales/topics/health/nhswales/review/?lang=en
An Innovative Management System Responds to the Needs of Tanzania's Most Vuln...JSI
APHA International Health Poster Session - HIV/AIDS
The Government of Tanzania is working to address a critical challenge faced by child protection and HIV practitioners: How to implement a systematic response that engages both community and facility based providers in a connected system to ensure most vulnerable children (MVC) and their families holistically receive social welfare, protection services, and HIV related needs.
The USAID Community Health and Social Welfare system Strengthening Program (CHSSP), implemented by JSI Research & Training Institute, Inc., collaborated with the Tanzania Department of Social Welfare to design, and finalize a National Integrated Case Management System (NICMS). This document sets forth a harmonized, standardized, and systematic structure for the care and protection of MVC and their families, with the goal of improving access to and integration of protection, social welfare, and health services, including HIV continuum of care. The NICMS is responsive to MVC needs including HIV-specific social issues and includes: strengthening bi-directional linkages and referrals between social welfare, Protection, and HIV clinical providers; Coordinating civil society organizations dealing with MVC; strengthening MVC committees and ensure supportive supervision at all levels. All components ultimately contribute towards expanding access to HIV care and treatment services, enhancing ART retention and adherence, improving referrals and linkages.
Recommendations/Conclusions: NICMS is a valuable initiative to serve MVC holistically, and has successfully integrated the Tanzanian health social welfare and Protection sectors to provide services across the continuum of care.
Learning Disabilities: Share and Learn Webinar – 27 April 2017NHS England
Creating a Dynamic Approach to Risk Stratification (including dynamic risk registers)
This webinar aims to share learning to help TCPs in developing a dynamic approach to risk stratification (which includes a developing dynamic risk register). The webinar provides the latest guidance from the national Transforming Care Programme and a real life example of how a TCP has approached the problem on the ground.
This webinar covers some of the same material as one run previously for North region TCPs on dynamic risk registers but also builds on that material with the latest guidance.
Strengthening Community Capacity for Effective Advocacy: A Strategy Developme...Humentum
Robert Musoke, PATH Uganda; Bernard Byagageire, PATH Uganda; Jennifer Gaberu, PATH Uganda. Presentation made during Humentum's Capacity for Humanity conference, February 2018.
Six principles for engaging people and communitiesJeremy Taylor
Slides presented at King's Fund on 1 November 2016. How to make real the vision in the Five Year Forward View of "a new relationship with patients and communities"? We know a lot about the "what" and the "who" of implementation. But the "how" is still a mess. What high impact actions would make a difference to driving this agenda? I offer some thoughts. These slides are not entirely self-explanatory without the accompanying talk. Please feel free to get in touch to explore further!
Session Two: Barriers to investment in research to find a disease modifying therapy or cure for dementia.
Dr. Luc Truyen, MD, PhD, VP Neuroscience External Affairs and Chair, Johnson&Johnson, Global Fight against !lzheimer’s Disease
Session Four: Exploring the financial mechanisms that can be harnessed to increase investment in
dementia.
Mr. George Vradenburg, Convenor, The Global CEO Initiative on Alzheimer's and Chairman of USAgainstAlzheimer’s & World Dementia Council Member
Significance of Questions on Doctrine - Herbert E. DouglassprimesteCuvantul
May 11, 2013 - Sacramento Central SDA Church - Dr. Herb Douglass spoke about the significance of the book that divided the Adventists after 1957.
Multumesc fratelui Douglass pentru fisierul PPT!
, "We have now before us the alpha of this danger. The omega will be of a most startling nature." Selected Messages, vol.1, 197
What is the Omega?
•In the context of the alpha crisis, Ellen White describes a vision about the soon coming omega apostasy among Adventists. "The enemy of souls has sought to bring in the supposition that a great reformation was to take place among Seventh-day Adventists, and that this reformation would consist in giving up the doctrines which stand as the pillars of our faith, and engaging in a process of reorganization. Were this reformation to take place, what would result? The principles of truth that God in His wisdom has given to the remnant church, would be discarded. Our religion would be changed. The fundamental principles that have sustained the work for the last fifty years would be accounted as error. A new organization would be established. Books of a new order would be written. A system of intellectual philosophy would be introduced. The founders of this system would go into the cities, and do a wonderful work. The Sabbath of course, would be lightly regarded, as also the God who created it. Nothing would be allowed to stand in the way of the new movement. The leaders would teach that virtue is better than vice, but God being removed, they would place their dependence on human power, which, without God, is worthless. Their foundation would be built on the sand, and storm and tempest would sweep away the structure." Selected Messages, vol. 1, 204, 205.
A reformation inspired by the devil was to take place, and it would consist "in giving up the doctrines which stand as the pillars of our faith."
What are the pillars of our Adventist faith? They are as follows:
•The nature of Christ
•The sanctuary service
•The spirit of prophecy
•The Three Angels' Messages (exposing the papacy, Babylon, ecumenism, explaining the Sabbath-Sunday-question, exalting the law of God, etc.)
•The state of the dead and the exposure of spiritualism
"I was shown three steps—the First, Second, and Third Angels' Messages. Said my accompanying angel, 'Woe to him who shall move a block or stir a pin of these messages. The true understanding of these messages is of vital importance. The destiny of souls hangs upon the manner in which they are received.' I was again brought down through these messages, and saw how dearly the people of God had purchased their experience. It had been obtained through much suffering and severe conflict. God had led them along step by step, until He had placed them upon a solid, immovable platform. I saw individuals approach the platform and examine the foundation. Some with rejoicing immediately stepped upon it. Others commenced to find fault with the foundation. They wished improvements made, and then the platform would be more perfect, and the people much happier. Some stepped off the platform to examine it and declared it to be laid wrong. But I saw that nearly all sto
Los capítulos en este libro fueron primeramente publicados como artículos de revista. Estos artículos tenían la intención, no de fijar tiempos, sino que alertar a los lectores sobre la posibilidad de que ya hu-biésemos entrado o que estemos justo entrando en el tiempo del zarandeo.
Información acerca de este triste tiempo de gran apostasía en la IASD1 ha estado a nuestra disposición durante muchos años. Descripciones detalladas nos son familiares y están en muchos libros del Espíritu de Profecía. Podemos haber leído estas predicciones pero tal vez no nos hemos detenido lo suficiente como para meditar en ellas.
Sitio Web - https://ministeriopalmoni.wordpress.com/
Facebook - https://www.facebook.com/MinisterioPalmoni
Twitter - https://twitter.com/MinistryPalmoni
Google Plus - https://plus.google.com/114003190106843997086
YouTube: https://www.youtube.com/channel/UCMSebXBYNLXP4ZRG36fgOjQ
Slideshare: http://www.slideshare.net/MinisterioPalmoni
Wikia: http://es.ministeriopalmoni.wikia.com
Realising the Value Stakeholder Event -Workshop: How does the system support Nesta
Workshop D - How does the system support communities/individuals and how could it do it better?
The levers and drivers that national bodies put in place and how these are used locally have a significant impact on working in partnership with communities and patients. These levers and drivers include regulation, targets, outcomes measures, financial flows, annual contracting cycles, clinical standards, workforce training and revalidation etc.
This workshop will draw upon your experience and evidence to address two questions:
How these levers and drivers get in the way of working in partnership with patients and communities?
What is the best blend of approaches to support commissioners and providers locally to harness the energy of patients and communities
Guidance for commissioners of financially, environmentally, and socially sust...JCP MH
This guide supports commissioners, local health authorities and providers to think broadly, but practically, about building sustainable, resilient communities that have the potential, over time, to reduce mental ill health.
Sustainable commissioning involves making sure services make the most effective use of financial, environmental and social resources. This includes commissioning services that support secondary (reducing relapse) and tertiary (improving rehabilitation) prevention. It is these aspects, rather than primary preventative measures, that are the focus for this guide. The issue of primary prevention is discussed in the Guidance for commissioning public mental health services.
This guide has been written by a group of experts in mental health and sustainability, in consultation with service users and patients, and strengthened by input from a local government and public health perspective. The content is primarily evidence-based but ideas deemed to be best practice by expert consensus have also been included.
By the end of this guide, readers should:
- understand the concept of sustainability in mental health care, and how using this commissioning framework can create sustainable services
- be aware of the legislation relating to sustainability that the NHS is required to meet
- understand what sustainable commissioning looks like in practice
- understand how and why improving the sustainability of mental health interventions will contribute to achieving the aims of both the mental health, public health, NHS, and social care strategies, as well as improving quality and productivity
- be able to commission sustainable mental health services and interventions.
Find out more and download all the guides published by the Joint Commissioning Panel for Mental Health at http://www.jcpmh.info.
NHS pathway towards an Integrated Care System.pptxMark Da Rocha
This presentation is about the milestone the NHS achieved here in the UK on 1st July 2022 on its roadmap to provide Integrated Care at a local level, nationally in the UK.
Mark Da Rocha is a Healthcare Projects specialist working in the NHS in the UK.
Presentation by Jo Ward, North West Social Prescribing Network Co-Chair: Social Prescribing Network and creative health agenda at the Health, wellbeing and the environment event on Monday 28 January 2019 at The Isla Gladstone Conservatory, Liverpool
Creating digital tools for mental health and employment support: the discover...Department of Health
This report maps out the needs of potential users of an online mental health and work assessment and support service, suggests key user groups and presents a set of design principles for any a potential future service.
Creating digital tools for mental wellbeing and employment support: pre-alpha...Department of Health
This slide-deck reports on the second phase user research and testing. It presents refined design briefs that can be used to inform future alpha stages and design of a future service. These are themed according to the three core user groups identified in the first phase:
(i) finding work
(ii) in and out of work
(iii) managing work.
Further information on:
- user testing details
- mock-ups of potential digital tools for people finding work
- mock-ups of potential digital tools for people moving in and out of work
- mock-ups of potential digital tools for people managing work
Global Dementia Legacy Event: Canada & France: Dr Etienne Hirsch & Dr Yves Jo...Department of Health
Session Five: The next goal – towards Canada, France, Japan and the United States.
Canada & France: Dr Etienne Hirsch, Director, Institute for Neurosciences, Cognitive sciences, Neurology and Psychiatry at INSERM and the French alliance for life and health science Aviesan & Dr Yves Joanette CIHR, Scientific Director, Canadian Institutes of Health Research (CIHR), Institute of Aging & World Dementia Council Member
Feature presentation - The economic case for action
Professor Martin Knapp, Director, Health &
Personal Social Services Research Unit, London School of Economics & Kings College London
Session Four: Exploring the financial mechanisms that can be harnessed to increase investment in
dementia.
Professor Andrew Lo, MIT Sloan Professor of Finance
Marc Wortman, Executive Director, Alzheimer’s Disease International (ADI) Department of Health
Session Three: To explore ways in which we can increase investment in innovation. Part 2 presents a case study of innovation across the globe and the need to continue global collaboration
Marc Wortman, Executive Director, Alzheimer’s Disease International (ADI)
Session Three: To explore ways in which we can increase investment in innovation. Part 2 presents a case study of innovation across the globe and the need to continue global collaboration
DY Suharya, Executive Director of Alzheimer's Indonesia
Session Three: To explore ways in which we can increase investment in innovation. Part 2 presents a case study of innovation across the globe and the need to continue global collaboration
Dr. Maria C. Carrillo, Vice President, Alzheimer’s Association US
Session 3: To explore ways in which we can increase investment in innovation. In part 1 panellists will highlight ways in which they are seeking to tackle barriers and find solutions, including through big data, patient involvement in clinical trials and social investment.
Mr. Stephen Johnston, Co-Founder, Aging2.0 & Partner, Generator Ventures
Session 3: To explore ways in which we can increase investment in innovation. In part 1 panellists will highlight ways in which they are seeking to tackle barriers and find solutions, including through big data, patient involvement in clinical trials and social investment.
Mr. Tom Wright CBE, Group CEO, Age UK
Session Two: Barriers to investment in research to find a disease modifying therapy or cure for dementia
Dr Neil Buckholtz , Director of Neuroscience, the National Institute on Aging (NIA), National Institutes of Health (NIH)
Global Dementia Legacy Event: Ms Inez Jabalpurwala, President and CEO, Brain ...Department of Health
Session Two: Barriers to investment in research to find a disease modifying therapy or cure for dementia
Ms Inez Jabalpurwala, President and CEO, Brain Canada Foundation
Global Dementia Legacy Event: Raj Long, Senior Regulatory OfficerDepartment of Health
Session Two: Barriers to investment in research to find a disease modifying therapy or cure for dementia.
Raj Long, Senior Regulatory Officer – Integrated Development, Global Health at the Bill & Melinda Gates Foundation & World Dementia Council Member
Session Two: Barriers to investment in research to find a disease modifying therapy or cure for dementia.
Elisabetta Vaudano DVM PhD, Coordinator Scientific Pillar, Principal Scientific Manager, Innovative Medicines Initiative
Session Two: Barriers to investment in research to find a disease modifying therapy or cure for dementia.
John Ryan, Acting Director of the European Commission Public Health Directorate
Session Two: Barriers to investment in research to find a disease modifying therapy or cure for dementia.
Professor Lefkos Middleton, Professor of Neurology, Neuroepidemiology and Ageing Research at School of Public Health, Imperial College London
Dr Shekhar Saxena, Director of the Department of Mental Health and Substance Abuse at World Health Organization (WHO) & Technical Advisor to the World Dementia Council
HOT NEW PRODUCT! BIG SALES FAST SHIPPING NOW FROM CHINA!! EU KU DB BK substit...GL Anaacs
Contact us if you are interested:
Email / Skype : kefaya1771@gmail.com
Threema: PXHY5PDH
New BATCH Ku !!! MUCH IN DEMAND FAST SALE EVERY BATCH HAPPY GOOD EFFECT BIG BATCH !
Contact me on Threema or skype to start big business!!
Hot-sale products:
NEW HOT EUTYLONE WHITE CRYSTAL!!
5cl-adba precursor (semi finished )
5cl-adba raw materials
ADBB precursor (semi finished )
ADBB raw materials
APVP powder
5fadb/4f-adb
Jwh018 / Jwh210
Eutylone crystal
Protonitazene (hydrochloride) CAS: 119276-01-6
Flubrotizolam CAS: 57801-95-3
Metonitazene CAS: 14680-51-4
Payment terms: Western Union,MoneyGram,Bitcoin or USDT.
Deliver Time: Usually 7-15days
Shipping method: FedEx, TNT, DHL,UPS etc.Our deliveries are 100% safe, fast, reliable and discreet.
Samples will be sent for your evaluation!If you are interested in, please contact me, let's talk details.
We specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on. Products are exported to USA, Canada, France, Korea, Japan,Russia, Southeast Asia and other countries.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
6. From LINks to Local HealthWatch – continuing LINk functions and acquiring new functions LOCAL HEALTHWATCH ‘ local consumer voice for health and social care’ Influencing Help shape the planning of health and social care services signposting Help people access and make choices about care advisory Advocacy for individuals making complaints about healthcare Strong LOCAL consumer voice on views and experiences to influence better health and social care outcomes Respected, authoritative, influential, credible and very visible within the community from 2013/14 seat on the health and wellbeing board Joint Strategic Needs Assessment and Joint Health and Wellbeing Strategy scrutinising quality of service provision informing the commissioning decision-making process empowering people - helping people understand choice providing local, evidence based information representing the collective voice
7.
8. Strengthening the collective voice of patients and the public ‘ Local champion voice’ Local HealthWatch Community groups, Voluntary organisations ‘ National champion voice’ Monitor Carers health and well being board Local authority HealthWatch England The public and patient voice - their views and experiences - influencing better health and social care outcomes Older people Working age individuals Mental health Disability groups … others BME groups OSC / scrutiny function NHS Commissioning Board DH – Secretary of State CQC GP consortia Providers Ombudsman Arrangements will ensure sharing of information to involve, consult and protect the public advisory influencing continuous dialogue