Dr. Ashok Kumar Kapoor discusses coronary heart disease (CHD) and strategies for prevention and diagnosis. Some key points:
- CHD is a leading cause of death worldwide, responsible for over 6 million deaths per year. Risk factors include age, family history, smoking, diabetes, hypertension, and high cholesterol.
- Symptoms of a heart attack can include chest pain or pressure, sweating, jaw pain, and breathlessness. Early diagnosis is important through methods like electrocardiograms, stress tests, echocardiograms, and coronary angiography.
- Lifestyle changes can help prevent CHD, such as a healthy diet, regular exercise, maintaining a healthy weight, reducing stress,
High prevalence of hypertension in older persons (nearly one of two subjects aged >60 years). It is a significant and often asymptomatic chronic disease. HTN is a major cause of morbidity and mortality among aged. Hypertension in older adults is generally defined by SBP ≥ 140 mmHg or DBP ≥ 90 mmHg over two clinic visits (systolodiastolic HTN)
Isolated systolic hypertension (ISH): SBP of ≥140 with a DBP of <90 mm Hg.
The recognition and treatment of HTN should be a priority among elderly. Controlled, RCTs have shown that treatment of hypertension decreases the incidence of complications in older adults.
High prevalence of hypertension in older persons (nearly one of two subjects aged >60 years). It is a significant and often asymptomatic chronic disease. HTN is a major cause of morbidity and mortality among aged. Hypertension in older adults is generally defined by SBP ≥ 140 mmHg or DBP ≥ 90 mmHg over two clinic visits (systolodiastolic HTN)
Isolated systolic hypertension (ISH): SBP of ≥140 with a DBP of <90 mm Hg.
The recognition and treatment of HTN should be a priority among elderly. Controlled, RCTs have shown that treatment of hypertension decreases the incidence of complications in older adults.
High blood pressure is also known as hypertension. Blood pressure is the amount of force exerted against the walls of the arteries as blood flows through them.
High blood pressure: Symptoms, Causes and controlCyrilDsouza9
High blood pressure (HBP) is common among senior citizens in the United States and is a serious condition that can significantly increase the probability of having coronary heart disease, a heart attack, stroke, kidney failure, and other health problems and risks.
In literal terms, "blood pressure" is the force of blood pushing against arterial walls while the heart pumps out blood. A large force over a long period of time is called HBP and it can cause extensive damage to the body.
It is very important that senior citizens understand what their blood pressure means and how they can effectively prevent and, if necessary, treat HBP.
People who participate in the elder care of senior citizens should also be familiar with HBP and how they can encourage behaviors that facilitate healthy blood movement.
On May 7, 2016, St. Paul's Hospital's Pacific Adult Congenital Heart Disease (PACH) Clinic invited patients and their families to learn more about navigating life as an adult with congenital heart disease. Over 150 participants attended the clinic.
We aim at providing a comprehensive Cardiac Care experience, by combining medical management, interventional cardiology, cardiac surgery and non-interventional options along with customized Cardiac Rehabilitation programs, making it the choice best heart hospital in Mumbai. For more information visit us on https://bit.ly/2MXUQTQ
Watch Best yoga for heart blockage preferred by Best cardiologist in Hyderabad for heart patients.
Heart is the important organ in the body and is the reason for human life. According to the best cardiologist in Hyderabad there is a rapid increase in heart diseases with the increase in technology and changes in life style irrespective of age, gender and region.
For more information vistit https://www.plus100years.com/how-to-do-best-yoga-for-heart-blockage/
Lifestyle Modification For The Prevention of Heart DiseaseAdarsha Neupane
Here's a Presentation made by GROUP C on Lifestyle Modification For The Prevention of Heart Disease. This slide was created for Problem Based Learning (PBL) wrap up session Held At Kathmandu University- Birat Medical College Teaching Hospital (BMCTH).
feel free to Download and share this slide. You can leave comments for further improvement on other presentations. Thankyou. Cheers!
High blood pressure is also known as hypertension. Blood pressure is the amount of force exerted against the walls of the arteries as blood flows through them.
High blood pressure: Symptoms, Causes and controlCyrilDsouza9
High blood pressure (HBP) is common among senior citizens in the United States and is a serious condition that can significantly increase the probability of having coronary heart disease, a heart attack, stroke, kidney failure, and other health problems and risks.
In literal terms, "blood pressure" is the force of blood pushing against arterial walls while the heart pumps out blood. A large force over a long period of time is called HBP and it can cause extensive damage to the body.
It is very important that senior citizens understand what their blood pressure means and how they can effectively prevent and, if necessary, treat HBP.
People who participate in the elder care of senior citizens should also be familiar with HBP and how they can encourage behaviors that facilitate healthy blood movement.
On May 7, 2016, St. Paul's Hospital's Pacific Adult Congenital Heart Disease (PACH) Clinic invited patients and their families to learn more about navigating life as an adult with congenital heart disease. Over 150 participants attended the clinic.
We aim at providing a comprehensive Cardiac Care experience, by combining medical management, interventional cardiology, cardiac surgery and non-interventional options along with customized Cardiac Rehabilitation programs, making it the choice best heart hospital in Mumbai. For more information visit us on https://bit.ly/2MXUQTQ
Watch Best yoga for heart blockage preferred by Best cardiologist in Hyderabad for heart patients.
Heart is the important organ in the body and is the reason for human life. According to the best cardiologist in Hyderabad there is a rapid increase in heart diseases with the increase in technology and changes in life style irrespective of age, gender and region.
For more information vistit https://www.plus100years.com/how-to-do-best-yoga-for-heart-blockage/
Lifestyle Modification For The Prevention of Heart DiseaseAdarsha Neupane
Here's a Presentation made by GROUP C on Lifestyle Modification For The Prevention of Heart Disease. This slide was created for Problem Based Learning (PBL) wrap up session Held At Kathmandu University- Birat Medical College Teaching Hospital (BMCTH).
feel free to Download and share this slide. You can leave comments for further improvement on other presentations. Thankyou. Cheers!
Deliverable 3 - Confidence Intervals
Dear Nelda,
same feedback. Your #5 is good.
A couple of errors.
We don't use STDEVA.
You need to use cell references. You cannot copy and paste the values if you have the calculated ones.
Check your calculations for the confidence intervals. Again, avoid rounding the numbers. The critical value is incorrect.
Get in touch with Allisha if anything is unclear.
Running Head: THE IMPACT OF CHRONIC ILLNESS 1
THE IMPACT OF CHRONIC ILLNESS 2
The Impact of Chronic Illness
Student name
Professor
Professor
Course
Date of submission
According to the data analysis model that was used, the patient exhibited and illustrated system that that clearly outlined a heart condition. Therefore the questionnaire helped in a significant way to establish the situation and mitigation that could be put in place to handle the development of the illness. In most cases, chronic heart diseases come along with another related state that attacks the condition. They include obesity, high blood pleasure, and massive consumption of alcohol, which risk an individual to attracting top changes of a heart attack. The patient has been attending regular checkups since the mass body weight was increasing beyond far beyond the bar (Stephen Buetow, 2011). To prove that he was suffering from heart disease the first evaluation platform was enquiring about the level of blood pleasure. Unfortunately, the test showed immersive levels of blood pleasure since it was at stage two, giving a 140 greater systolic. This was determined after the patient blood test had electrolytes, a high level of nitrogen, and more a high level of keratinizing. This test was a process that has been done in less than 12 months before the day of determination. This was the first day when the patient has experienced such a high level of blood pleasure and had not begun taking medication.
Nevertheless, the taking of medication would play a significant role in regulating the condition. In a broad scope, the patient exhibited a diuretic condition; it has a great connection to the kidney. As a result, chlorthalidone, indapamide, and metazine would help in handling the illness and stabilizing blood pleasure (Ashley Welch, 2018).
After establishing that the patient had a heart condition, and it was getting worse, the family member was in a position to convince purse upon his acceptance and the diagnosis processes. From a professional point of view, one of the primary reasons that were igniting the condition was poor diets, as indicated in the questionnaire, there was a need to manage foods as it was the primary source of cholesterol that was affecting the regular running of the heart. The worse of it all was that the patient did not participate in a vigorous activity that would enable the burring of excessive carioles that have excessively been taken. C.
Heart disease life expectancy: Heart disease is the main cause of death in Western countries, but it’s not all doom and gloom. In this article, you’ll learn about how to treat heart disease by looking at the different stages and treatments for heart disease, as well as the various ways you can reduce your risk.
Life expectancy after 1st heart attack: Heart disease life expectancy
If you have heart disease, your life expectancy may be shorter than if you don’t have heart disease. This is because heart disease is a leading cause of death in the United States.
There are several factors that can affect your life expectancy after a heart attack. These include the type and severity of your heart attack, how quickly you received treatment for your heart attack, and your overall health.
However, there are some things you can do to increase your life expectancy after a heart attack. These include getting regular exercise, eating a healthy diet, and maintaining a healthy weight.
You also need to get timely medical care after a heart attack. If you don’t receive timely medical care, your chances of dying from your heart attack will be greater. Heart disease life expectancy.
Life expectancy after heart attack in 20s
If you have suffered a heart attack, your life expectancy may be reduced by up to 15 years. This is according to a study that was published in the British Medical Journal. Heart disease life expectancy
The study looked at data from more than 200,000 people who had suffered a heart attack. It found that those who survived the attack had a life expectancy that was 15 years shorter than those who died as a result of the attack.
The study also found that the length of time spent in hospital after the heart attack was a significant factor in determining life expectancy. People who spent less than two weeks in hospital had a life expectancy that was six years shorter than those who spent longer periods in hospital. Heart disease life expectancy.
If you have suffered a heart attack, it is important to speak to your doctor as soon as possible about your health prospects. There are treatments available that can help you survive and enjoy a long and healthy life.
Life expectancy with coronary artery disease
The life expectancy for those with coronary artery disease (CAD) has increased in recent years, but it is still not as good as that of those without the condition. In fact, the average life expectancy for someone with CAD is now around 78 years. This improvement is due to a number of factors, including better treatments and improvements in lifestyle. However, there is still a lot of work to be done to improve the life expectancy of those with CAD.
One important area of focus is reducing the risk of heart attack and stroke. By understanding your risk factors and taking steps to reduce them, you can help ensure a longer life. Additionally, continuing education about heart health is important for all individuals, regardless of their risk factors.
There is a chance you are already aware of the importance of Exercise and ‘staying fit’ for keeping your weight in control. But the benefits of exercise are far more than this!
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
HOT NEW PRODUCT! BIG SALES FAST SHIPPING NOW FROM CHINA!! EU KU DB BK substit...GL Anaacs
Contact us if you are interested:
Email / Skype : kefaya1771@gmail.com
Threema: PXHY5PDH
New BATCH Ku !!! MUCH IN DEMAND FAST SALE EVERY BATCH HAPPY GOOD EFFECT BIG BATCH !
Contact me on Threema or skype to start big business!!
Hot-sale products:
NEW HOT EUTYLONE WHITE CRYSTAL!!
5cl-adba precursor (semi finished )
5cl-adba raw materials
ADBB precursor (semi finished )
ADBB raw materials
APVP powder
5fadb/4f-adb
Jwh018 / Jwh210
Eutylone crystal
Protonitazene (hydrochloride) CAS: 119276-01-6
Flubrotizolam CAS: 57801-95-3
Metonitazene CAS: 14680-51-4
Payment terms: Western Union,MoneyGram,Bitcoin or USDT.
Deliver Time: Usually 7-15days
Shipping method: FedEx, TNT, DHL,UPS etc.Our deliveries are 100% safe, fast, reliable and discreet.
Samples will be sent for your evaluation!If you are interested in, please contact me, let's talk details.
We specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on. Products are exported to USA, Canada, France, Korea, Japan,Russia, Southeast Asia and other countries.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
263778731218 Abortion Clinic /Pills In Harare ,ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group of receptionists, nurses, and physicians have worked together as a teamof receptionists, nurses, and physicians have worked together as a team wwww.lisywomensclinic.co.za/
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
3. Definitions of Health
“the condition of being Sound in Body, Mind or spirit,
especially freedom from physical disease or pain”
(Webster ) “soundness of body or mind: that condition
in which its functions are duly and efficiently
discharged”
Getwell Medical Center
4. WHO Definition of Health?
WHO definition of Health
“Health is a state of complete physical, mental and social
wellbeing and not merely an absence of disease or
infirmity” + ability to lead a “socially and economically
productive life”
Getwell Medical Center
6. Incidence of Coronary Heart Disease
• Worldwide 6 to 7 million Deaths.
• In U.S.A, 12 million Americans have CAD.
• 800,000 new Heart Attacks a year and 450,000
recurrent
• UK - 300,000
• INDIA - 2.5 million
• UAE - 10 to 12,000
• Women develop the disease later by 10 years.
• Sudden Death above 35 y-80% are due to Heart attack.
Getwell Medical Center
7. HEART ATTACK (MYOCARDIAL INFARCTION)
• A heart attack is caused by a blood clot
obstructing a coronary artery-muscle death.
• Chest Pain occurs because of the dying muscle.
Electrical instability causes V. Fibrillation and
sudden Death.
Getwell Medical Center
8. Heart Attack Symptoms
• Chest pressure
• Sweating
• Jaw pain
• Heart burn
• Arm pain
• Indigestion
• Back Pain
• Nausea
• Breathlessness
Getwell Medical Center
9. Risk Factors
• Age
• Gender
• Family history
• High Blood Lipids – Cholesterol
• Tri LDL
• Smoking
• Hypertension
• Diet
• Diabetes Mellitus
• Sedentary
• High stress-type A
• Homocys
• Fibrinogen etc
Getwell Medical Center
10. Coronary Angiogram
Digital Image Processing
RCA RCA LCX
Getwell Medical Center
11. Rotabalator and Stenting
Long standing Hypertension
Hyperlipidemia
Chr. Stable Angina
Twice Balloon Angioplasty
C.S 47, F
Getwell Medical Center
12. DIAGNOSIS OF CHD-EARLY AND ACCURATE
SCREENING FOR CHD:
1. AGE: After crossing 35
2. Family History
3. Smokers
4. Diabetes Mellitus
5. Hypertension
6. Obese
7. High Blood Lipids
8. Stressful, sedentary life.
Getwell Medical Center
13. DIAGNOSIS OF CHD
RESTING ECG:
Recorded by ECG machine.
Can be done at home in emergency.
Any doubtful chest discomfort-do it.
May be normal in 40% of the cases.
Chest Pain-ALWAYS DO IT.
Getwell Medical Center
14. STRESS TEST
• Exercise Test-done
on Treadmill or
Bicycle.
• Best screening
test.
• Negative test with
good exercise.
• Tolerance rules out
significant CHD.
Getwell Medical Center
15. ECHOCARDIOGRAPHY
• Evaluates Heart
structure and
function.
• Can localize areas
of heart attack.
• Stress Echo can
improve the
diagnostic value of
stress test.
• Options of color,
Doppler, 2D and
even 3D study.
Getwell Medical Center
16. CORONARY ANGIOGRAPHY
The Gold Standard for the diagnosis of CHD.
Invasive procedure.
A plastic tube passed into the heart and dye is
injected.
Film taken and studied for coronary Blockages.
Getwell Medical Center
17. HOW TO PREVENT A HEART ATTACK
TIPS:
Healthy life style,
Regular exercise: 20 to 30 minutes of Walking,
cycling or on a treadmill.
Maintain Ideal Weight.
Open air exercise.
Getwell Medical Center
18. Prevention
Eat Healthy food:
• Plenty of fresh fruits, green vegetables, Salads-
High Fibre diet.
• Avoid oily , Fried foods, cheese butter, ghee and
creams.
• Avoid excess of alcohol.
Getwell Medical Center
19. Life-Style Assessment
Scoring: Record the number of checkmarks (0 to 5) for
each of the twelve areas. Add up the numbers to
determine your total score.
48 to 60 Healthier than average life-style
30 to 47 Average life -style
0 to 29 Below average: need for improvement
If you scored less than 3 in any one area, there is a
need for improvement in that area
Getwell Medical Center
20. STRESS & condition, a response to a physical threat or
Stress is a common
ITS MANAGEMENT
psychological distress, that generates a host of chemical and hormonal
reactions in the body. In essence, the body prepares to fight or flee,
pumping more blood to the heart and muscles and shutting down all
non-essential functions. As a temporary state, this reaction serves the
body well to defend itself. However, when the stress reaction is
attenuated, the normal physical functions that have been either
exaggerated or shut down become dysfunctional.
Getwell Medical Center
21. Stress is pervasive, life threatening.
• An estimated 75% to 90% of visits to primary-care
physicians are for stress-related complaints.
• In 2002, people in the United States alone bought
nearly $17.2 billion worth of antidepressants and anti-
anxiety drugs, up more than 10 percent from 2001.
• According the Centers for Disease Control, adult use of
antidepressants almost tripled from 1988 to 1994 and
1999 to 2000.
• A Harvard study showed individuals who lived in a
state of high anxiety were four and a half times more
likely to suffer sudden cardiac death than non-anxious
individuals.
Getwell Medical Center
22. Take the Stress Test
See if any of the following symptoms apply to you or someone you know:
Irritability: Shorter fuse these days, the little things make you angrier?
Sense of humor: Laughing less, too serious?
Worry: Reliving or projecting future anxious emotional experiences?
Depressed, resigned over the way things are?
Excessiveness: Eating, drinking too much, too many mood-altering stimulants?
Forgetfulness: Can’t remember little things lately, have mental gridlock?
Aches and pains: Recurring headaches, frequent gastrointestinal distress,
tension in face, jaw, shoulders, back or chest?
Nervousness: Talking faster, more than in the past?
Fatigue: Feeling run-down a lot? Tired, but can’t get restful sleep?
Illness: Suffering allergies, colds, flu and other ailments more often?
Time pressure: Often feel as if there is not enough time, too much to do?
If you answered yes to three or more of these questions, there’s a good chance
you are experiencing some degree of chronic stress, but take heart: You can
control your stress and HeartMath will help.
Getwell Medical Center
23. A HeartMath Tip: Take five minutes several times a
day, whether or not you’re feeling especially stressed,
to try these simple steps adapted from the HeartMath
Attitude Breathing® tool.
Focus on your heart as you breathe in.
Concentrate on a positive feeling or attitude as you
breathe out.
Lock in this new feeling as you continue to breathe it
in and out through your heart.
As you become adept at using this HeartMath tool,
select new feelings and to help you “de-stress”
Getwell Medical Center
24. Benefits of Stress Reduction
• Improved health, feeling of well-being and quality of life
• Improved intuition, memory and cognitive function
• More energy during the day, restful sleep at night
• More heartfelt feelings like love, appreciation and kindness
• Less impatience, irritability, fits of anger
Getwell Medical Center
25. Smoking - The Facts
Cigarette Smoking contains the following
Nocotine
Tar
Carbon monoxide
Many Disease are caused by Smoking.
Smoking affect other people
Getwell Medical Center
26. Is it ever too late to quit?
No, it's never too late to quit. Quit smoking now to start feeling these benefits.
• 20 minutes after quitting:
Your blood pressure drops back to normal.
The temperature in your hands and feet returns to normal.
• 8 hours after quitting:
• The carbon monoxide (a gas that can be toxic) in your blood drops to
normal.
• 24 hours after quitting:
Your chance of having a heart attack goes down.
• 2 days after quitting:
You can taste and smell things better.
• 2 weeks to 3 months after quitting:
You have better blood flow.
Your lungs are working better.
Getwell Medical Center
27. • 1 to 9 months after quitting:
Coughing, sinus congestion, fatigue, and shortness of breath decrease.
Your lungs start to function better, lowering your risk of lung infections.
• 1 year after quitting:
You reduce your risk for heart disease by half.
• 5 to 15 years after quitting:
Your risk of having a stroke is the same as someone who never smoked.
• 10 years after quitting:
Your risk of lung cancer is nearly the same as someone who never smoked.
Your risk of cancer of the mouth, throat, esophagus, bladder, kidney, and
pancreas also decrease.
• 15 years after quitting:
Your risk of heart disease is now the same as someone who has never
smoked.
Getwell Medical Center
28. CHOLESTROL
• Low fat, low cholesterol diet
• Exercise
• STATINS
Getwell Medical Center
29. Exercise
Exercise can help your body in many ways. Aside from helping you to keep a healthy body
weight, exercise increases your mobility, protects against bone loss, reduces your stress levels,
and helps you feel better about yourself. And, research has shown that people who exercise are
less likely to develop heart disease, high blood pressure, and high cholesterol levels
Before you start an exercise program
• You are taking a prescription medicine.
• You have ever had any kind of heart problem, especially a heart attack.
• You have diabetes.
• You have problems with your bones or joints.
• You have high blood pressure and do not take medicine for it.
• You have a family history of coronary artery disease.
• You are a man over 45 or a woman over 50, and you are not used to doing even moderate
levels of exercise.
• You smoke.
• You are very overweight
Getwell Medical Center
30. What kind of exercise should I do?
There are 3 categories of exercises:
Cardiovascular
Strength-building
Flexibility
Cardiovascular exercise is also known as aerobic exercise
For example, walking, jogging, swimming, and cycling are aerobic activities.
Strength-building and flexibility exercises are known as anaerobic exercise.
Cardiovascular Exercise
A simple definition of cardiovascular exercise is any exercise that raises your
heart rate to a level where you can still talk, but you start to sweat a little.
Getwell Medical Center
31. CONCLUSION
In the conclusion , I can only say that in spite of fast and stressful life the
lifestyle needs to be healthy.
Prevention is better than cure
The state of art modern technology and the early diagnosis can make all the
difference in the form of life and death.
Genetic manipulation and thus producing new coronary artery is the ultimate
goal.
Getwell Medical Center