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BASICS OF CATHLAB
HARDWARE
• DR HASIT JOSHI SIR
• DR TARUN MADAN SIR
• DR RIYAZ SIR
• DR NIKUL SIR
• COMPONENTS OF GUIDEWIRE
• PROPERTIES OF AN IDEAL GUIDEWIRE
• TYPES OF GUIDEWIRES
COMPONENTS OF GUIDEWIRE
•Central core composed of stainless steel or nitinol.
•Distal tip – made of stainless steel /platinum/tungsten.
•Coating -Silicone, Polytetrafluroethylene (PTFE) or hydrophilic
substances
CROSS SECTION OF A
GUIDEWIRE
CENTRAL CORE
• Basic component of the guidewire.
• Contributes to trackability, torquability and push
transmission.
• Support provided by the guidewire depends on
strength of material constituting the central core and
its thickness.
• When the core extends to the tip, it is called a
unibody guidewire.
CORE
CORE MATERIAL
Stainless steel
•Strong
•Flexible
•Better torqueability
•Greater tactile feedback
Nitinol
• Elastic
• No shape retention
when bend
• Less torqueability
• Less tactile feedback
TIP STYLE
COVERS
RADIOPAQUE TIP
Platinum coils placed at wire tip( distal 2 – 3 cm)
provide visibilty (radio opaque)
PROPERTIES OF AN IDEAL
GUIDEWIRE
• Push transmission or steerability
Ability of a guidewire tip to be delivered to the desired position
in a vessel.
• Torque transmission
Ability to transmit rotational forces from operators hand to the tip
of guidewire.
Increased core thickness increases torquability.
Trackability : Ability to advance interventional devices on the
guidewire.
Flexibility:
Ability to bend with direct pressure.
Minimize vascular trauma.
Tip elasticity:
Shape memory retention of the distal tip throughout the entire
procedure.
Tip visibility and markers:
Allows for visualization of distal tip in the vessel lumen.
Help in estimation of lesion length and choosing length of
balloon catheters and stents.
Durability of the wire: kink resistance(wire can be used for
multiple lesions)
Tactile feedback: feel of the wire tip
Prolapse tendency:
Tendency of the guidewire tip to kink once passed into a vessel.
Common with floppy tip guidewires.
Problem when lesions are very tight or lesions are in angulated
vessels.
After crossing the lesion, beneficial – reduces the possibility of
guide wire trauma to distal vessel.
TYPES OF GUIDEWIRES
•Depending on the tip load the guidewires can be classified as
balanced, extra support or floppy.
•Tip load is defined as the force needed to bend a wire when
exerted on a straight guide wire tip, at 1 cm from the tip.
•As tip load increases, the wire becomes stiffer
– provides more support
– more prone to perforation.
TIP LOAD
BALANCED GUIDEWIRES
•Tip load range between 0.5 and 0.9 g.
•Balance between flexibility, support and steerability.
•Constitute the bulk of use in any cath. lab -also called
frontline guidewires or workhorse guidewires.
EXTRA-SUPPORT GUIDEWIRES
•Extra-support guidewires are designed for cases where
additional support is needed for device delivery.
•Include intravascular tortuosity , calcification, noncompliance,
previously deployed stents or when bulky devices are used.
• The tip load is more than 0.9g.
FLOPPY WIRES
• Soft guidewires are useful in negotiating a tortuous anatomy.
• May lack body support for device tracking.
• Once lesion is crossed, soft guidewire may be exchanged with
a extra support guidewire.
• Extra support guidewires provide enhanced tracking of
balloons and stents.
Diameter: 0.36mm(0.014 inch)
Spring coil length:11cm
Guide wire length:180/300cm
Tip: Straight/J
Diameter:0.23mm(0.009 inch)/0.36mm(0.014 inch)
Spring coil length:11cm
Guide wire length:190/300cm
Tip: Straight
Diameter: 0.36mm(0.014 inch)
Spring coil length:4cm
Guide wire length:180/300cm
Tip: Straight/J
WHISPER GUIDE WIRE
Tip load:0.8/1/1.2 gm
Diameter: 0.36mm(0.014 inch)
Radiopaque length : 3cm
Guide wire length:190/300cm
Tip: Straight
ASAHI SION BLUE
Tip load: 0.5g
Diameter: 0.36mm(0.014 inch)
Spring coil length:20cm
Guide wire length:180/300cm
Tip: Straight/J
RUNTHROUGH NS
Dual Core –
Main shaft core of SS &
Distal core – Nitinol.
Tip-nitinol shaping ribbon
Tip load:3/4.5/6/12gm
Diameter: 0.36mm(0.014 inch)
Spring coil length:11cm
Guide wire length:180cm
Tip: Straight
Diameter: 0.23(0.009)/0.36mm(0.014 inch)
Spring coil length:20cm
Guide wire length:180cm
Tip: Straight
CROSS IT SERIES
(100/200/300/400 XT)
Tip load:1.7/4.7/6.2/8.7gm
Diameter: 0.36mm(0.014 inch)
Radiopaque length : 3cm
Guide wire length:190/300cm
Tip: Straight/J
SUMMARY
• Central core of guidewires are composed of stainless
steel or nitinol
• Based on the tip load the guidewires can be classified as
balanced, extra support or floppy.
• Balanced guidewires are called “workhorse guidewires”
• Extra-support guidewires are designed for cases where
additional support is needed for device delivery
• Heavy-duty guidewires are not suited as primary
guidewires because of their stiffness and poor torque
control
GUIDING CATHETERS
Functions of a Guide Catheter
• Support for device advancement
• Conduit for device and wire transport
• Vehicle for contrast injection
• Measurement of Pressure
• Different makes, shapes, sizes & uses
Diagnostic vs Guide catheters
• Stiffer shaft
• Larger internal diameter (ID)
• Shorter & more angulated tip (110º vs. 90º), non tapering tip
• Re-enforced construction (3 vs 2 layers).
PARTS OF A CATHETER
•Usual length= 100 cm
•Tertiary curve in some catheters
CATHETER SIZE
• Catheter size in French
For each given size - ID is
either standard, large
CROSS SECTION OF CATHETER
Strength
Support/Flexibi
lity
Kink resistance
Polyurethane
or
Polyethylene
1:1 Torque
Kink resistance
Stainless steel/
Kevlar
Internal lumen
Smooth or lubricious
material
Device compatibility
PTFE
(Polytetrafluoroethylene)
like Teflon
IMPORTANT FEATURES OF A GUIDE
CATHETER
• Preformed curves & configurations, optimum support
• Adequate lumen & device compatibility
• Easy to handle, torque control, kink resistance
• Atraumatic tip
SIDE HOLE VS NO SIDE HOLE
Side holes are useful where the pressure gets frequently damped as in
RCA interventions, CTO interventions or sole surviving artery or
left main interventions
Advantages
– Prevent catheter damping (occlusion of the coronary ostium)
– Allow additional blood flow out of tip, to perfuse the artery.
– Avoid catastrophic dissections in the ostium of the artery
Disadvantages
– False sense of security because now, aortic pressure, and not the
coronary pressure is being monitored.
– Suboptimal opacification
– Reduction in back up support provided because of weakness of
catheter shaft and the kinking at side holes
Most commonly used guides
• Judkins, Amplatz, and Extra-
back-up guides
• Others include - Multipurpose
for RCA bypass or a high left
main (LM) takeoff
• LIMA catheter for - right and
left coronary bypass graft
THE JUDKINS GUIDE
• Primary (90º), secondary (180º),
and tertiary (35Âş) curves fit aortic
root anatomy
• As 1⁰ curve fixed Intubates small
segment of ostium - ↓risk of trauma
• Engage the LM ostium without
much manipulation
JUDKINS GUIDE
• Selected according to
– width of the ascending aorta
– location of the ostia to be cannulated
– orientation of the coronary artery
segment proximal to the target lesion
• Segment between the primary and secondary curve of the
Judkins left guide should fit width of ascending aorta
ex:3.5 cm,4 cm, 4.5 cm
• Locations of the ostia:- can be low, high or more anteriorly or
posteriorly oriented
• For Asian patients, a 3.5 cm Judkins left guide usually fits well
• Superior direction of the LM or narrow aortic root - smaller
size guide
• Horizontal or wide aortic root - JL with long secondary curve
(size 5 or 6)
LIMITATIONS OF JUDKINS GUIDE
• As 1⁰ curve is fixed - may not be
co-axial with the artery
• may be difficult to pass balloons
- as catheter makes an angle of
90Âş with ostium
• JL- point of contact on ascending
aorta - very high & narrow- ↑
chance of prolapse &
dislodgement
• JR- no point of contact on asc
Aorta - extremely poor support
THE AMPLATZ GUIDE
• Secondary curve rest against the
noncoronary posterior aortic cusp
• Offers firm platform for
advancement of device
• Best in the case of a short LM,
with downgoing left circumfl ex
artery (LCX)
• Tip points slightly downward -
higher danger of ostial injury
causing dissection
AMPLATZ GUIDE
• Selection of the proper size for
an Amplatz guide is essential
– Size 1 is for the smallest aortic
root
– size 2 for normal
– size 3 for large roots
• Attempts to force engagement of
Amplatz guide- increase risk of
complication
AMPLATZ GUIDE
• If tip does not reach the ostium and keep lying below it - guide
is too small
• If tip lies above the ostium - guide is too large
• When RCA ostium is very high - left Amplatz guide may be
used to engage the right ostium
MULTIPURPOSE GUIDE
• Straight with a single minor bend at the tip
• For RCA bypass graft or a high left main (LM) takeoff
LONG TIP CATHETERS
• XB, EBU
• Advantages
– coaxial intubation
– better support and stability
– lack of bends -improve
advancement of devices,decrease
the loss of supportive forces
– safety
EXTRA-BACK-UP GUIDE
• Long tip forms a fairly straight line
with the LM axis or the proximal
ostial RCA
• Long secondary curve - abut the
opposite aortic wall
• So tip in the coronary artery is not
easily displaced
• Provide a very stable platform
OTHER CATHETERS
• Arani
 Double angle 90 º curve sits on ascending aorta in S
configuration and is therefore useful for RCA with horizontal
take-off & shephered crook RCA
 Primary and secondary curve provides two contact points on
the opposite side of aorta thus providing tremendous back-up
support
• 3 DRC - Three dimensional right curve - for tortuous, bent
anatomy and posterior or superior take off of RCA
6/19/20
CURVE SELECTION FACTORS
• Aortic Width
• Coronary Anatomy
• French Size
• Active vs. Passive Support
• Native Coronary vs. CABG
• Amount of Calcium in Target Vessel
AORTIC WIDTH
www.medtronic.com
FRENCH SIZE INFLUENCE
• Historically, 8F guides were necessary to deliver devices
because of their larger internal lumens.
• Current 6-7F catheters have internal lumens just as large as
previous generation 8F catheters.
• Large guides require side-holes more frequently to improve
perfusion
BACK-UP SUPPORT
• Ability of the guiding catheter to remain in position and
provide a stable platform for the advancement of
interventional equipment
• There are 3 main types of back up support
– Passive
– Active
– Balanced
PASSIVE SUPPORT
• Strong support given by
– inherent design of a guide with good back-up against opposite
aortic wall
– stiffness from manufactured material
• Additional manipulation is generally not required
• Mainly passive
– Amplatz
Active support
• Active support is typically achieved by
1. Manipulation of the guide - into a configuration
conforming the aortic root
2. Deep-Seating – Intubation with deep engagement of the
guide into the coronary vessels
Balanced Support
• Rely on the inherent property of shaft and shape for coaxiallity, but
can be manipulated in cases requiring extra support
– Judkins
– EBU
CORONARYANATOMY OSTIAL
VARIATIONS
Coronary ostial orientation:
• superior
• horizontal
• inferior
• shepherd’s crook (RCA’s
only)
Coronary ostial location:
• high
• low
• anterior
• posterior
CORONARY OSTIAL TAKEOFFS
• Horizontal
Inferior
Superior
COMMON TAKEOFFS- LEFT CORONARY
ARTERY
• Horizontal
Inferior
Superior
COMMON TAKEOFFS RIGHT
CORONARYARTERY
Horizontal
Inferior
Superior
CORONARY OSTIAL TAKEOFFS
SHEPHERD’S CROOK (RCA ONLY)
RCA origin is not only superiorly oriented but also courses superiorly
to some extent before making a U-turn.
GUIDE CATHETER SELECTION
• MOST IMPORTANT REQUIREMENT: CO-AXIAL
ALIGNMENT
Non-Coaxial Coaxial
GUIDING CATHETER SUPPORT
Simple coaxial
alignment,
without support
Coaxial alignment, with
extra support from Sinus
of Valsalva
Coaxial alignment,
with power support
from opposite wall of
aorta
JR4 Hockey Stick EBU
SHORT AND LONG LMCA
• If the LM is short and there is no acute angle at the bifurcation
with the LCX - left Judkins
• If the LM is long and the angle between the LM and LCX is
acute - extra-backup guide
• (Tip of the guide is very close to the ostium of the LCX so the
acuity of the LM and LCX angle is nullified)
HIGH LEFT TAKEOFF- LCA
AL 1.5 EBU 3.5
RCA INTERVENTIONS
• Usual - JR or Hockey stick guide
• If extra support – CTO, tortuosity – AL1
• Abnormal take off of RCA from aorta esp inf orientations -
MP guide
• Tortuous or bent anatomy, posterior and superior take off of
RCA - 3DRC
Shepherd’s crook deformity of RCA
www.medtronic.com
Dramatic upturn with a near 180 degree switch back turn
GUIDES FOR CORONARYANOMALIES
• Important to be aware of variations of coronary anomalies.
• Systematically search in other aortic sinuses when the vessel in
question does not arise.
• Anomalous artery from the right sinus -
– Left, right Amplatz ,Multipurpose
• Anomalous artery from the left sinus
– Larger left Judkins ,Left Amplatz ,Multipurpose
GUIDES FOR ANOMALOUS CORONARY ARTERIES
ARISING
FROM THE LEFT SINUS
• When RCA arises from the left
cusp usually it is anterior and
cephalad to LM
• JL with secondary curve one
size larger than one used for the
patient’s LM
• Pushed deep in the left sinus ,
causing it to make an anterior
and cephalad U-turn
• Larger curve will prevent guide
to engage LM
SVG and LIMA
• Usual – JR
• Abnormal positions and take offs
MP or AL1
• LCB/RCB
• Internal mammary artery - IMA
catheter , LCB
– IMA Catheter is designed for
both Rt. And left Internal
Mammary arteries
– shaped like a JR catheter but with
a steeply angled tip (80 to 85Âş).
IMA
LCB
CHOICE OF CATHETERS FOR
INTERVENTIONS VIA RADIALARTERY
• Ikari catheter – for trans radial intervention
• Ikari L can generate greater
backup force than JL in TRI
Ikari R (IR) 1.5 Ikari L
(IL) 4
MOTHER AND CHILD
• Improve the delivery of
coronary stents to complex
lesions
• Child catheters 4/5 F 120 cm
• Mother catheter - 6 F
guiding catheter 100cm
• Superior trackability of the
4F child catheter
• Increased backup support of
the mother-child system
• 4F mother-child system
provided > 90% success rate
GUIDELINER CATHETER
• GuideLiner catheter is a coaxial
guiding catheter extension
delivered through a standard
guiding catheter on a monorail
• Permits very deep intubation of the
target vessel, thus providing
backup support to facilitate stent
delivery across heavily calcified
lesions in tortuous vessels
CONTRAST MEDIA USED
IN
CATH LAB
CLASSIFICATION
HIGH OSMOLAR CONTRAST GENTS
( HOCA)
LOW OSMOLAR CONTRAST
AGENTS (LOCA)
IONIC IONIC
NON-IONIC
HOCA
• In use since 1950
 Urovist
 Urografin
 Angiovist
 Conray
 Renografin
 Renovist
 Hypaque
LOCA
NONIONIC IONIC
Ultravist Hexabrix
Omnipaque
Visipaque
Oxilan
IDEAL CM IN ANGIOGRAPHY
• Water soluble
• Chemical and heat soluble
• Biologically inert ( no antigenic )
• Low viscocity
• Low or iso - osmolar , excreted
• Selectively through the kidney
• Safe
• inexpensive
CONTRAST MEDIA SPECIFICATIONS
PRODUCT CHEMICAL
STRUCTURE
% SALT
CONCENTRATION
% IODINE
CONCENTRATI
ON
IODINE
(MG/ML)
VISCOCITY
37 (CPS)
OSMOLALI
TY
(MOSM/K
G)
IOHEXOL
240
NONIONIC NONE 24 240 3.4 520
IOPROMIDE
240
NONIONIC < 0.1 24 240 2.8 483
IOHEXOL
300
NONIONIC NONE 30 300 6.3 672
IOPROMIDE
300
NONIONIC <0.1 30 300 4.9 607
IOHEXOL
350
NONIONIC NONE 35 350 10.4 844
IOPROMIDE
370
NONIONIC NONE 37 370 10.0 774
PRODUCT CHEMICAL
STRUCTURE
% SALT
CONCENTRATION
% IODINE
CONCENTRATION
IODINE
(MG
/ML)
VISCOCITY
37(CPS)
OSMOLALITY
(MOSM/KG)
IODIXANOL NONIONIC NONE 27 270 6.3 290
IOPROMIDE NONIONIC NONE 32 320 11.8 290
THANK YOU

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Coronary Artery Disease - HARDWARE IN CATH LAB.pptx

  • 1. BASICS OF CATHLAB HARDWARE • DR HASIT JOSHI SIR • DR TARUN MADAN SIR • DR RIYAZ SIR • DR NIKUL SIR
  • 2. • COMPONENTS OF GUIDEWIRE • PROPERTIES OF AN IDEAL GUIDEWIRE • TYPES OF GUIDEWIRES
  • 3. COMPONENTS OF GUIDEWIRE •Central core composed of stainless steel or nitinol. •Distal tip – made of stainless steel /platinum/tungsten. •Coating -Silicone, Polytetrafluroethylene (PTFE) or hydrophilic substances
  • 4. CROSS SECTION OF A GUIDEWIRE
  • 5. CENTRAL CORE • Basic component of the guidewire. • Contributes to trackability, torquability and push transmission. • Support provided by the guidewire depends on strength of material constituting the central core and its thickness. • When the core extends to the tip, it is called a unibody guidewire.
  • 7. CORE MATERIAL Stainless steel •Strong •Flexible •Better torqueability •Greater tactile feedback Nitinol • Elastic • No shape retention when bend • Less torqueability • Less tactile feedback
  • 10. RADIOPAQUE TIP Platinum coils placed at wire tip( distal 2 – 3 cm) provide visibilty (radio opaque)
  • 11. PROPERTIES OF AN IDEAL GUIDEWIRE • Push transmission or steerability Ability of a guidewire tip to be delivered to the desired position in a vessel. • Torque transmission Ability to transmit rotational forces from operators hand to the tip of guidewire. Increased core thickness increases torquability.
  • 12. Trackability : Ability to advance interventional devices on the guidewire. Flexibility: Ability to bend with direct pressure. Minimize vascular trauma. Tip elasticity: Shape memory retention of the distal tip throughout the entire procedure.
  • 13. Tip visibility and markers: Allows for visualization of distal tip in the vessel lumen. Help in estimation of lesion length and choosing length of balloon catheters and stents. Durability of the wire: kink resistance(wire can be used for multiple lesions) Tactile feedback: feel of the wire tip
  • 14. Prolapse tendency: Tendency of the guidewire tip to kink once passed into a vessel. Common with floppy tip guidewires. Problem when lesions are very tight or lesions are in angulated vessels. After crossing the lesion, beneficial – reduces the possibility of guide wire trauma to distal vessel.
  • 15. TYPES OF GUIDEWIRES •Depending on the tip load the guidewires can be classified as balanced, extra support or floppy. •Tip load is defined as the force needed to bend a wire when exerted on a straight guide wire tip, at 1 cm from the tip. •As tip load increases, the wire becomes stiffer – provides more support – more prone to perforation.
  • 17. BALANCED GUIDEWIRES •Tip load range between 0.5 and 0.9 g. •Balance between flexibility, support and steerability. •Constitute the bulk of use in any cath. lab -also called frontline guidewires or workhorse guidewires.
  • 18. EXTRA-SUPPORT GUIDEWIRES •Extra-support guidewires are designed for cases where additional support is needed for device delivery. •Include intravascular tortuosity , calcification, noncompliance, previously deployed stents or when bulky devices are used. • The tip load is more than 0.9g.
  • 19. FLOPPY WIRES • Soft guidewires are useful in negotiating a tortuous anatomy. • May lack body support for device tracking. • Once lesion is crossed, soft guidewire may be exchanged with a extra support guidewire. • Extra support guidewires provide enhanced tracking of balloons and stents.
  • 20. Diameter: 0.36mm(0.014 inch) Spring coil length:11cm Guide wire length:180/300cm Tip: Straight/J
  • 21. Diameter:0.23mm(0.009 inch)/0.36mm(0.014 inch) Spring coil length:11cm Guide wire length:190/300cm Tip: Straight
  • 22. Diameter: 0.36mm(0.014 inch) Spring coil length:4cm Guide wire length:180/300cm Tip: Straight/J
  • 23. WHISPER GUIDE WIRE Tip load:0.8/1/1.2 gm Diameter: 0.36mm(0.014 inch) Radiopaque length : 3cm Guide wire length:190/300cm Tip: Straight
  • 24. ASAHI SION BLUE Tip load: 0.5g Diameter: 0.36mm(0.014 inch) Spring coil length:20cm Guide wire length:180/300cm Tip: Straight/J
  • 25. RUNTHROUGH NS Dual Core – Main shaft core of SS & Distal core – Nitinol. Tip-nitinol shaping ribbon
  • 26. Tip load:3/4.5/6/12gm Diameter: 0.36mm(0.014 inch) Spring coil length:11cm Guide wire length:180cm Tip: Straight
  • 27. Diameter: 0.23(0.009)/0.36mm(0.014 inch) Spring coil length:20cm Guide wire length:180cm Tip: Straight
  • 28. CROSS IT SERIES (100/200/300/400 XT) Tip load:1.7/4.7/6.2/8.7gm Diameter: 0.36mm(0.014 inch) Radiopaque length : 3cm Guide wire length:190/300cm Tip: Straight/J
  • 29. SUMMARY • Central core of guidewires are composed of stainless steel or nitinol • Based on the tip load the guidewires can be classified as balanced, extra support or floppy. • Balanced guidewires are called “workhorse guidewires” • Extra-support guidewires are designed for cases where additional support is needed for device delivery • Heavy-duty guidewires are not suited as primary guidewires because of their stiffness and poor torque control
  • 31. Functions of a Guide Catheter • Support for device advancement • Conduit for device and wire transport • Vehicle for contrast injection • Measurement of Pressure • Different makes, shapes, sizes & uses
  • 32. Diagnostic vs Guide catheters • Stiffer shaft • Larger internal diameter (ID) • Shorter & more angulated tip (110Âş vs. 90Âş), non tapering tip • Re-enforced construction (3 vs 2 layers).
  • 33. PARTS OF A CATHETER •Usual length= 100 cm •Tertiary curve in some catheters
  • 34. CATHETER SIZE • Catheter size in French For each given size - ID is either standard, large
  • 35. CROSS SECTION OF CATHETER Strength Support/Flexibi lity Kink resistance Polyurethane or Polyethylene 1:1 Torque Kink resistance Stainless steel/ Kevlar Internal lumen Smooth or lubricious material Device compatibility PTFE (Polytetrafluoroethylene) like Teflon
  • 36. IMPORTANT FEATURES OF A GUIDE CATHETER • Preformed curves & configurations, optimum support • Adequate lumen & device compatibility • Easy to handle, torque control, kink resistance • Atraumatic tip
  • 37. SIDE HOLE VS NO SIDE HOLE Side holes are useful where the pressure gets frequently damped as in RCA interventions, CTO interventions or sole surviving artery or left main interventions Advantages – Prevent catheter damping (occlusion of the coronary ostium) – Allow additional blood flow out of tip, to perfuse the artery. – Avoid catastrophic dissections in the ostium of the artery
  • 38. Disadvantages – False sense of security because now, aortic pressure, and not the coronary pressure is being monitored. – Suboptimal opacification – Reduction in back up support provided because of weakness of catheter shaft and the kinking at side holes
  • 39. Most commonly used guides • Judkins, Amplatz, and Extra- back-up guides • Others include - Multipurpose for RCA bypass or a high left main (LM) takeoff • LIMA catheter for - right and left coronary bypass graft
  • 40. THE JUDKINS GUIDE • Primary (90Âş), secondary (180Âş), and tertiary (35Âş) curves fit aortic root anatomy • As 1⁰ curve fixed Intubates small segment of ostium - ↓risk of trauma • Engage the LM ostium without much manipulation
  • 41. JUDKINS GUIDE • Selected according to – width of the ascending aorta – location of the ostia to be cannulated – orientation of the coronary artery segment proximal to the target lesion • Segment between the primary and secondary curve of the Judkins left guide should fit width of ascending aorta ex:3.5 cm,4 cm, 4.5 cm
  • 42. • Locations of the ostia:- can be low, high or more anteriorly or posteriorly oriented • For Asian patients, a 3.5 cm Judkins left guide usually fits well • Superior direction of the LM or narrow aortic root - smaller size guide • Horizontal or wide aortic root - JL with long secondary curve (size 5 or 6)
  • 43. LIMITATIONS OF JUDKINS GUIDE • As 1⁰ curve is fixed - may not be co-axial with the artery • may be difficult to pass balloons - as catheter makes an angle of 90Âş with ostium • JL- point of contact on ascending aorta - very high & narrow- ↑ chance of prolapse & dislodgement • JR- no point of contact on asc Aorta - extremely poor support
  • 44. THE AMPLATZ GUIDE • Secondary curve rest against the noncoronary posterior aortic cusp • Offers firm platform for advancement of device • Best in the case of a short LM, with downgoing left circumfl ex artery (LCX) • Tip points slightly downward - higher danger of ostial injury causing dissection
  • 45. AMPLATZ GUIDE • Selection of the proper size for an Amplatz guide is essential – Size 1 is for the smallest aortic root – size 2 for normal – size 3 for large roots • Attempts to force engagement of Amplatz guide- increase risk of complication
  • 46. AMPLATZ GUIDE • If tip does not reach the ostium and keep lying below it - guide is too small • If tip lies above the ostium - guide is too large • When RCA ostium is very high - left Amplatz guide may be used to engage the right ostium
  • 47. MULTIPURPOSE GUIDE • Straight with a single minor bend at the tip • For RCA bypass graft or a high left main (LM) takeoff
  • 48.
  • 49. LONG TIP CATHETERS • XB, EBU • Advantages – coaxial intubation – better support and stability – lack of bends -improve advancement of devices,decrease the loss of supportive forces – safety
  • 50. EXTRA-BACK-UP GUIDE • Long tip forms a fairly straight line with the LM axis or the proximal ostial RCA • Long secondary curve - abut the opposite aortic wall • So tip in the coronary artery is not easily displaced • Provide a very stable platform
  • 51. OTHER CATHETERS • Arani  Double angle 90 Âş curve sits on ascending aorta in S configuration and is therefore useful for RCA with horizontal take-off & shephered crook RCA  Primary and secondary curve provides two contact points on the opposite side of aorta thus providing tremendous back-up support
  • 52. • 3 DRC - Three dimensional right curve - for tortuous, bent anatomy and posterior or superior take off of RCA
  • 54. CURVE SELECTION FACTORS • Aortic Width • Coronary Anatomy • French Size • Active vs. Passive Support • Native Coronary vs. CABG • Amount of Calcium in Target Vessel
  • 56. FRENCH SIZE INFLUENCE • Historically, 8F guides were necessary to deliver devices because of their larger internal lumens. • Current 6-7F catheters have internal lumens just as large as previous generation 8F catheters. • Large guides require side-holes more frequently to improve perfusion
  • 57. BACK-UP SUPPORT • Ability of the guiding catheter to remain in position and provide a stable platform for the advancement of interventional equipment • There are 3 main types of back up support – Passive – Active – Balanced
  • 58. PASSIVE SUPPORT • Strong support given by – inherent design of a guide with good back-up against opposite aortic wall – stiffness from manufactured material • Additional manipulation is generally not required • Mainly passive – Amplatz
  • 59. Active support • Active support is typically achieved by 1. Manipulation of the guide - into a configuration conforming the aortic root 2. Deep-Seating – Intubation with deep engagement of the guide into the coronary vessels
  • 60. Balanced Support • Rely on the inherent property of shaft and shape for coaxiallity, but can be manipulated in cases requiring extra support – Judkins – EBU
  • 61. CORONARYANATOMY OSTIAL VARIATIONS Coronary ostial orientation: • superior • horizontal • inferior • shepherd’s crook (RCA’s only) Coronary ostial location: • high • low • anterior • posterior
  • 62. CORONARY OSTIAL TAKEOFFS • Horizontal Inferior Superior
  • 63. COMMON TAKEOFFS- LEFT CORONARY ARTERY • Horizontal Inferior Superior
  • 65. CORONARY OSTIAL TAKEOFFS SHEPHERD’S CROOK (RCA ONLY) RCA origin is not only superiorly oriented but also courses superiorly to some extent before making a U-turn.
  • 66. GUIDE CATHETER SELECTION • MOST IMPORTANT REQUIREMENT: CO-AXIAL ALIGNMENT Non-Coaxial Coaxial
  • 67. GUIDING CATHETER SUPPORT Simple coaxial alignment, without support Coaxial alignment, with extra support from Sinus of Valsalva Coaxial alignment, with power support from opposite wall of aorta JR4 Hockey Stick EBU
  • 68. SHORT AND LONG LMCA • If the LM is short and there is no acute angle at the bifurcation with the LCX - left Judkins • If the LM is long and the angle between the LM and LCX is acute - extra-backup guide • (Tip of the guide is very close to the ostium of the LCX so the acuity of the LM and LCX angle is nullified)
  • 69. HIGH LEFT TAKEOFF- LCA AL 1.5 EBU 3.5
  • 70. RCA INTERVENTIONS • Usual - JR or Hockey stick guide • If extra support – CTO, tortuosity – AL1 • Abnormal take off of RCA from aorta esp inf orientations - MP guide • Tortuous or bent anatomy, posterior and superior take off of RCA - 3DRC
  • 71. Shepherd’s crook deformity of RCA www.medtronic.com Dramatic upturn with a near 180 degree switch back turn
  • 72. GUIDES FOR CORONARYANOMALIES • Important to be aware of variations of coronary anomalies. • Systematically search in other aortic sinuses when the vessel in question does not arise. • Anomalous artery from the right sinus - – Left, right Amplatz ,Multipurpose • Anomalous artery from the left sinus – Larger left Judkins ,Left Amplatz ,Multipurpose
  • 73. GUIDES FOR ANOMALOUS CORONARY ARTERIES ARISING FROM THE LEFT SINUS • When RCA arises from the left cusp usually it is anterior and cephalad to LM • JL with secondary curve one size larger than one used for the patient’s LM • Pushed deep in the left sinus , causing it to make an anterior and cephalad U-turn • Larger curve will prevent guide to engage LM
  • 74. SVG and LIMA • Usual – JR • Abnormal positions and take offs MP or AL1 • LCB/RCB • Internal mammary artery - IMA catheter , LCB – IMA Catheter is designed for both Rt. And left Internal Mammary arteries – shaped like a JR catheter but with a steeply angled tip (80 to 85Âş). IMA LCB
  • 75. CHOICE OF CATHETERS FOR INTERVENTIONS VIA RADIALARTERY
  • 76.
  • 77. • Ikari catheter – for trans radial intervention • Ikari L can generate greater backup force than JL in TRI Ikari R (IR) 1.5 Ikari L (IL) 4
  • 78. MOTHER AND CHILD • Improve the delivery of coronary stents to complex lesions • Child catheters 4/5 F 120 cm • Mother catheter - 6 F guiding catheter 100cm • Superior trackability of the 4F child catheter • Increased backup support of the mother-child system • 4F mother-child system provided > 90% success rate
  • 79. GUIDELINER CATHETER • GuideLiner catheter is a coaxial guiding catheter extension delivered through a standard guiding catheter on a monorail • Permits very deep intubation of the target vessel, thus providing backup support to facilitate stent delivery across heavily calcified lesions in tortuous vessels
  • 81. CLASSIFICATION HIGH OSMOLAR CONTRAST GENTS ( HOCA) LOW OSMOLAR CONTRAST AGENTS (LOCA) IONIC IONIC NON-IONIC
  • 82. HOCA • In use since 1950  Urovist  Urografin  Angiovist  Conray  Renografin  Renovist  Hypaque
  • 84. IDEAL CM IN ANGIOGRAPHY • Water soluble • Chemical and heat soluble • Biologically inert ( no antigenic ) • Low viscocity • Low or iso - osmolar , excreted • Selectively through the kidney • Safe • inexpensive
  • 85. CONTRAST MEDIA SPECIFICATIONS PRODUCT CHEMICAL STRUCTURE % SALT CONCENTRATION % IODINE CONCENTRATI ON IODINE (MG/ML) VISCOCITY 37 (CPS) OSMOLALI TY (MOSM/K G) IOHEXOL 240 NONIONIC NONE 24 240 3.4 520 IOPROMIDE 240 NONIONIC < 0.1 24 240 2.8 483 IOHEXOL 300 NONIONIC NONE 30 300 6.3 672 IOPROMIDE 300 NONIONIC <0.1 30 300 4.9 607 IOHEXOL 350 NONIONIC NONE 35 350 10.4 844 IOPROMIDE 370 NONIONIC NONE 37 370 10.0 774
  • 86. PRODUCT CHEMICAL STRUCTURE % SALT CONCENTRATION % IODINE CONCENTRATION IODINE (MG /ML) VISCOCITY 37(CPS) OSMOLALITY (MOSM/KG) IODIXANOL NONIONIC NONE 27 270 6.3 290 IOPROMIDE NONIONIC NONE 32 320 11.8 290