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Guiding Catheters, Wires, and
Balloons: Equipment and
Results
Disclosure
• SB: Medtronic, BSc, Abbott
Vascular,Gilead
• Advisory Board: Medtronic, Abbott
Vascular, Philips
• All faculty disclosures are available on
the CRF Events App and online at
www.crf.org/tct
PTCA-Fracturing and Splitting Plaque
Design Characteristics of PTCA Balloons
• Over the wire (OTW)
• Rapid exchange (RX), Monorail
• Perfusion
• Fixed wire
• Cutting balloon
• Scoring balloon-Angiosculpt
Over the Wire (OTW)
• Consists of a balloon catheter with a movable guidewire
passing through the entire length of its lumen
• OTW requires 2 operators
• OTW provides better pushability
• 300 cm steerable wire is typically used
• Balloon catheter shafts are typically 145 to 155 cm long
• 25% of the system use in the U.S.
Product diagram courtesy of the manufacturer.
Over the Wire (OTW)
Advantages
• Ability to change wire without removing catheter
• Superior pushability because entire catheter body runs
over wire
Disadvantages
• Slightly larger profiles and shaft sizes
• Typically needs 2 operators
• Can take more time, requiring more fluoroscopy
Rapid Exchange (RX)
• Guidewire exits balloon catheter several centimeters
proximal to the distal tip
• Guidewire travels separately from the balloon catheter
• RX allows the operator to fix the wire with one hand &
advance the balloon with the other
• Single operator
• 180 through 195 cm steerable guidewire is typically
used
• 75% of the system use in the U.S. and greater than
95% in the remainder of the world
Product diagram courtesy of the manufacturer.
Rapid Exchange (RX)
Advantages
• Single operator
• Allows for quick exchanges over a short guidewire
Disadvantages
• Can’t reshape or exchange wire without losing position
• Guidewire difficult to place without support of balloon
• Pushability may be compromised due to the short wire
lumen
Balloon Overview
Illustrations are artist’s rendition and are not drawn to scale.
Working
Length
Proximal
Taper
Distal Taper
Tip Length
Tip Entry
Crossing
Profile
Balloon Dilatation Catheter
Components
2. Tip
3.
Markers
5. Catheter
Platform
1.
Balloon
4. Distal
Shaft
6. Coating
Illustrations are artist’s rendition and are not drawn to scale.
Characteristics
5 Key Balloon Attributes
• Entry – pushability and crossability
• Tracking – guidewire compatibility
• Crossability – profiles and transition
angles
• Dilatation – balloon material and
shoulders
• Withdrawal – rewrap
Definitions
• Nominal - the pressure (in atm.) at which the balloon
reaches its stated size
• Rated Burst Pressure - (RBP) pressure at which 99.9% of
all balloons will not burst at or below (with 95% confidence
interval)
• Working Range - range between nominal and rated burst
pressure
Compliance
• Compliant - Diameter increases in ratio with the increase in
inflation force (size of balloon may grow beyond the ceiling
of clinical safety)
• Non-compliant - Reach and maintain specified size
regardless of inflation pressure (little to no flexibility in
vessel sizing)
• Semi-compliant - Wide working pressure range with
controlled flexibility in balloon sizing
2.5
2.7
2.9
3.1
3.3
3.5
3.7
3.9
2 4 6 8 10 12 14 16 18 20
mm
atmSemi-Compliant
Non-Compliant
Compliant
Balloon Compliance
Multi-
Function
Very
Durable
Multi FunctionHighly
Crossable
Ultra-Tight
Lesions
Tortuous
Anatomy Pre-Dil & Post Dil
Heavy
Calcification
Balloon Differentiation
Compliant
Semi-Compliant
Marker Bands
• Radiopaque bands are swaggered into the shaft of the
balloon to determine balloon placement under fluoroscopy
• Bands can be either dual markers or a single center marker
Product diagram courtesy of the manufacturer.
Balloon Material
POC
PE
Nylon
PET
More Compliant
Less Compliant
Manufacturers use different balloon
materials and blends to design their
balloon portfolio.
Balloon Angioplasty Results
• Plain old balloon angioplasty (POBA )has a high rate of acute
recoil and restenosis rates vary from 10-60% depending on size,
diameter, complexity of the lesion and patient related factors.
• The use of the cutting balloon/angioscore have reduced these
rates and may be an option for complex procedures and small
less important branch vessels when stenting is not desired or
to prepare the lesion prior to stenting.
• Currently, PTCA is used traditionally for pre-dilating prior to
stenting and post-dilatiation to maximally expand a stent.
• The era of the drug eluting balloon (DEB) is on the horizon and
will change therapy depending on future randomized trials
Guide Catheters
Diagnostic Catheter Function
• Vehicle for contrast
injection
• Pressure measurement
• Angiographic
assessment
Guiding Catheter Function
• Conduit for device & wire
transport
• Support for equipment
advancement
• Vehicle for contrast
injection
• Pressure measurement
• Angiographic
assessment
Source: Grossman’s Cardiac Catheterization, Angiography, and Intervention
Basic Catheter Construction
• Materials
• Layers
• Catheter size
Outer LayerMiddle LayerInner Layer
Catheter Size
• Outer diameter = French size (5-10F)
• Inner diameter = Inches (thousandths)
• Length = Centimeters (cm)
ID=0.000”
OD=F
Length=cm
Curve/Tip Length
3.0
4.0
5.0
Judkins
Left
P
S
P = Primary Curve
S = Secondary Curve
Tip Length = P to S distance (cm)
Sources: Diagnostic and Therapeutic Cardiac Catheterization; Grossman’s
Cardiac Catheterization, Angiography, and Intervention
Curve Length
5.0
4.0
3.04
.
0
Lateral Wall Support
3.0
4.0
5.0
Sources: Diagnostic and Therapeutic Cardiac Catheterization; Grossman’s Cardiac Catheterization, Angiography, and Intervention
3.0
4.0
5.0
Tip Orientation
Backup Support
Sources: Diagnostic and Therapeutic Cardiac Catheterization; Grossman’s Cardiac Catheterization, Angiography, and
Intervention
Other Key Features
• Torque and tip control
• Soft tip
• Kink resistance
• Variety of shapes
• Adequate lumen sizes
• Radiopacity
Sources: Diagnostic and Therapeutic Cardiac Catheterization; Grossman’s Cardiac Catheterization, Angiography, and Intervention
Access Approach
• Femoral
 Extensive physician experience
 Easy catheter manipulation
 Bleeding at puncture site
• Radial & Brachial
 Little physician experience
 More difficult catheter manipulation
 Infrequent bleeding at puncture site
 Other possible complications
Source: The Manual of Interventional Cardiology
Aorta Anatomy
Normal
Small
Dilated
Source: The Manual of Interventional Cardiology
Acute
Superior
Inferior
Anterior
Posterior
Vessel Takeoff
Left Coronary Artery Catheter
Selection
• Judkins Left
 JL3
 JL3.5
 JL4, JL4ST (Short Tip)
 JL5
 JL6
• Amplatz
 AL1, AL2, AL3
• Multi Purpose (MPA)
Source: The Manual of Interventional Cardiology
Right Coronary Artery Catheter
Selection
• Judkins Right
 JR3
 JR3.5
 JR4, JR4ST (Short Tip)
 JR5
 JR6
• Amplatz
 AR1, AR2
• Hockey Stick
• Multi Purpose (MPA)
Source: The Manual of Interventional Cardiology
Graft Cannulation
Internal Mammary
Artery Grafts
Saphenous Vein Grafts
Guide Wires
Guide Wire
Guide Wire
Support Stiffness Malleabillity
Torque
Control
Guide Wire
Wire
Core
CoatTip
Core Material
Advantages
• Flexible
• Durable
Disadvantages
• Store torque
• Risk of fracture
NITINOL
Advantages
• Support
• Push
• Torque
Disadvantages
• Kink
• Less flexible
STEEL
Wire Coating
HYDROPHILLIC
• attracts water
• It is applied over polymer or
stainless steel (including tip
coils)
• Thin, non-slippery solid when
dry, needs lubrication to
perform
• Becomes gel when wet
• Reduces friction
• Increases trackability
HYDROPHOBIC
• repels water
• Silicone on working area of
wire, excluding tip
• No actuation/wetting required
• Reduces friction
• Increases trackability
Guide Wire - Coating
NO COATING
HYDROPHOBIC
HYDROPHILLIC
POLYMER AND
HYDROPHILLIC
TACTILE FEEDBACK
LUBRICITY
Guide Wire - Tip
TIP
LOAD
SHAPE
COAT
JOINTS
COILS
DESIGN
Tip Design
CORE-TO-TIP SHAPING RIBBON
Wire Selection
Workhorse Wires
• BMW
• BMW Universal
• Runthrough
• Hi-Torque Floppy
• Prowater
Extra Support
• ACS Intermediate
• Choice ES
• Stabilizer
• Wiggle Wire
CTO Wires
• Stiff
 Miracle
 Confianza
 Persuader
• Slippery
 Fielder FC,XT
 Pilot 50-200
Balloons, Guides, Wires
• Core products for the Interventional
cardiology community
• Each product is critical to the ultimate
success of the procedure
• They are used in every case and in many
cases several balloons and wires will be
utilized
• Enhancements to these products occur
regularly and help advance the field
Guiding Catheters, Wires, and
Balloons: Equipment and
Results
ABC’s of Interventional Cardiology
TCT 2014
THANK YOU!

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interventional cardiology, Guiding catheters, wires, and balloons equipment and results

  • 1. Guiding Catheters, Wires, and Balloons: Equipment and Results
  • 2. Disclosure • SB: Medtronic, BSc, Abbott Vascular,Gilead • Advisory Board: Medtronic, Abbott Vascular, Philips • All faculty disclosures are available on the CRF Events App and online at www.crf.org/tct
  • 4. Design Characteristics of PTCA Balloons • Over the wire (OTW) • Rapid exchange (RX), Monorail • Perfusion • Fixed wire • Cutting balloon • Scoring balloon-Angiosculpt
  • 5. Over the Wire (OTW) • Consists of a balloon catheter with a movable guidewire passing through the entire length of its lumen • OTW requires 2 operators • OTW provides better pushability • 300 cm steerable wire is typically used • Balloon catheter shafts are typically 145 to 155 cm long • 25% of the system use in the U.S. Product diagram courtesy of the manufacturer.
  • 6. Over the Wire (OTW) Advantages • Ability to change wire without removing catheter • Superior pushability because entire catheter body runs over wire Disadvantages • Slightly larger profiles and shaft sizes • Typically needs 2 operators • Can take more time, requiring more fluoroscopy
  • 7. Rapid Exchange (RX) • Guidewire exits balloon catheter several centimeters proximal to the distal tip • Guidewire travels separately from the balloon catheter • RX allows the operator to fix the wire with one hand & advance the balloon with the other • Single operator • 180 through 195 cm steerable guidewire is typically used • 75% of the system use in the U.S. and greater than 95% in the remainder of the world Product diagram courtesy of the manufacturer.
  • 8. Rapid Exchange (RX) Advantages • Single operator • Allows for quick exchanges over a short guidewire Disadvantages • Can’t reshape or exchange wire without losing position • Guidewire difficult to place without support of balloon • Pushability may be compromised due to the short wire lumen
  • 9. Balloon Overview Illustrations are artist’s rendition and are not drawn to scale. Working Length Proximal Taper Distal Taper Tip Length Tip Entry Crossing Profile
  • 10. Balloon Dilatation Catheter Components 2. Tip 3. Markers 5. Catheter Platform 1. Balloon 4. Distal Shaft 6. Coating Illustrations are artist’s rendition and are not drawn to scale.
  • 12. 5 Key Balloon Attributes • Entry – pushability and crossability • Tracking – guidewire compatibility • Crossability – profiles and transition angles • Dilatation – balloon material and shoulders • Withdrawal – rewrap
  • 13. Definitions • Nominal - the pressure (in atm.) at which the balloon reaches its stated size • Rated Burst Pressure - (RBP) pressure at which 99.9% of all balloons will not burst at or below (with 95% confidence interval) • Working Range - range between nominal and rated burst pressure
  • 14. Compliance • Compliant - Diameter increases in ratio with the increase in inflation force (size of balloon may grow beyond the ceiling of clinical safety) • Non-compliant - Reach and maintain specified size regardless of inflation pressure (little to no flexibility in vessel sizing) • Semi-compliant - Wide working pressure range with controlled flexibility in balloon sizing
  • 15. 2.5 2.7 2.9 3.1 3.3 3.5 3.7 3.9 2 4 6 8 10 12 14 16 18 20 mm atmSemi-Compliant Non-Compliant Compliant Balloon Compliance
  • 16. Multi- Function Very Durable Multi FunctionHighly Crossable Ultra-Tight Lesions Tortuous Anatomy Pre-Dil & Post Dil Heavy Calcification Balloon Differentiation Compliant Semi-Compliant
  • 17. Marker Bands • Radiopaque bands are swaggered into the shaft of the balloon to determine balloon placement under fluoroscopy • Bands can be either dual markers or a single center marker Product diagram courtesy of the manufacturer.
  • 18. Balloon Material POC PE Nylon PET More Compliant Less Compliant Manufacturers use different balloon materials and blends to design their balloon portfolio.
  • 19. Balloon Angioplasty Results • Plain old balloon angioplasty (POBA )has a high rate of acute recoil and restenosis rates vary from 10-60% depending on size, diameter, complexity of the lesion and patient related factors. • The use of the cutting balloon/angioscore have reduced these rates and may be an option for complex procedures and small less important branch vessels when stenting is not desired or to prepare the lesion prior to stenting. • Currently, PTCA is used traditionally for pre-dilating prior to stenting and post-dilatiation to maximally expand a stent. • The era of the drug eluting balloon (DEB) is on the horizon and will change therapy depending on future randomized trials
  • 21. Diagnostic Catheter Function • Vehicle for contrast injection • Pressure measurement • Angiographic assessment
  • 22. Guiding Catheter Function • Conduit for device & wire transport • Support for equipment advancement • Vehicle for contrast injection • Pressure measurement • Angiographic assessment Source: Grossman’s Cardiac Catheterization, Angiography, and Intervention
  • 23. Basic Catheter Construction • Materials • Layers • Catheter size Outer LayerMiddle LayerInner Layer
  • 24. Catheter Size • Outer diameter = French size (5-10F) • Inner diameter = Inches (thousandths) • Length = Centimeters (cm) ID=0.000” OD=F Length=cm
  • 25. Curve/Tip Length 3.0 4.0 5.0 Judkins Left P S P = Primary Curve S = Secondary Curve Tip Length = P to S distance (cm) Sources: Diagnostic and Therapeutic Cardiac Catheterization; Grossman’s Cardiac Catheterization, Angiography, and Intervention
  • 26. Curve Length 5.0 4.0 3.04 . 0 Lateral Wall Support 3.0 4.0 5.0 Sources: Diagnostic and Therapeutic Cardiac Catheterization; Grossman’s Cardiac Catheterization, Angiography, and Intervention 3.0 4.0 5.0 Tip Orientation
  • 27. Backup Support Sources: Diagnostic and Therapeutic Cardiac Catheterization; Grossman’s Cardiac Catheterization, Angiography, and Intervention
  • 28. Other Key Features • Torque and tip control • Soft tip • Kink resistance • Variety of shapes • Adequate lumen sizes • Radiopacity Sources: Diagnostic and Therapeutic Cardiac Catheterization; Grossman’s Cardiac Catheterization, Angiography, and Intervention
  • 29. Access Approach • Femoral  Extensive physician experience  Easy catheter manipulation  Bleeding at puncture site • Radial & Brachial  Little physician experience  More difficult catheter manipulation  Infrequent bleeding at puncture site  Other possible complications Source: The Manual of Interventional Cardiology
  • 31. Source: The Manual of Interventional Cardiology Acute Superior Inferior Anterior Posterior Vessel Takeoff
  • 32. Left Coronary Artery Catheter Selection • Judkins Left  JL3  JL3.5  JL4, JL4ST (Short Tip)  JL5  JL6 • Amplatz  AL1, AL2, AL3 • Multi Purpose (MPA) Source: The Manual of Interventional Cardiology
  • 33. Right Coronary Artery Catheter Selection • Judkins Right  JR3  JR3.5  JR4, JR4ST (Short Tip)  JR5  JR6 • Amplatz  AR1, AR2 • Hockey Stick • Multi Purpose (MPA) Source: The Manual of Interventional Cardiology
  • 34. Graft Cannulation Internal Mammary Artery Grafts Saphenous Vein Grafts
  • 36. Guide Wire Guide Wire Support Stiffness Malleabillity Torque Control
  • 38. Core Material Advantages • Flexible • Durable Disadvantages • Store torque • Risk of fracture NITINOL Advantages • Support • Push • Torque Disadvantages • Kink • Less flexible STEEL
  • 39. Wire Coating HYDROPHILLIC • attracts water • It is applied over polymer or stainless steel (including tip coils) • Thin, non-slippery solid when dry, needs lubrication to perform • Becomes gel when wet • Reduces friction • Increases trackability HYDROPHOBIC • repels water • Silicone on working area of wire, excluding tip • No actuation/wetting required • Reduces friction • Increases trackability
  • 40. Guide Wire - Coating NO COATING HYDROPHOBIC HYDROPHILLIC POLYMER AND HYDROPHILLIC TACTILE FEEDBACK LUBRICITY
  • 41. Guide Wire - Tip TIP LOAD SHAPE COAT JOINTS COILS DESIGN
  • 43. Wire Selection Workhorse Wires • BMW • BMW Universal • Runthrough • Hi-Torque Floppy • Prowater Extra Support • ACS Intermediate • Choice ES • Stabilizer • Wiggle Wire CTO Wires • Stiff  Miracle  Confianza  Persuader • Slippery  Fielder FC,XT  Pilot 50-200
  • 44. Balloons, Guides, Wires • Core products for the Interventional cardiology community • Each product is critical to the ultimate success of the procedure • They are used in every case and in many cases several balloons and wires will be utilized • Enhancements to these products occur regularly and help advance the field
  • 45. Guiding Catheters, Wires, and Balloons: Equipment and Results ABC’s of Interventional Cardiology TCT 2014 THANK YOU!