Keynote presentation by Dr Reiner Wassmann, International Rice Research Institute (IRRI) at CCAFS webinar 'Exploring GHG mitigation potential in rice production' on 18 September 2014.
This presentation was presented during the Plenary 1, Opening Ceremony of the Global Symposium on Soil Organic Carbon that took place in Rome 21-23 March 2017. The presentation was made by Mr. Luca Montanarella from EU Commission’s Joint Research Centre, in FAO Hq, Rome
Benefits of Soil Organic Carbon - an overviewExternalEvents
The presentation was given by Mr. Niels H. Batjes, ISRIC, during the GSOC Mapping Global Training hosted by ISRIC - World Soil Information, 6 - 23 June 2017, Wageningen (The Netherlands).
What follows is a detailed discussion of each of the 20 AERs of India and the 60 AESRs with reference to this climate, soil and land use, the distinguishing features of the AESRs are also mentioned.
Paddy fields account for around 20% of human-related emissions of methane — a potent greenhouse gas. Farmers normally flood rice fields throughout the growing season, meaning that methane is produced by microbes underwater as they help to decay any flooded organic matter
This presentation was presented during the Plenary 1, Opening Ceremony of the Global Symposium on Soil Organic Carbon that took place in Rome 21-23 March 2017. The presentation was made by Mr. Luca Montanarella from EU Commission’s Joint Research Centre, in FAO Hq, Rome
Benefits of Soil Organic Carbon - an overviewExternalEvents
The presentation was given by Mr. Niels H. Batjes, ISRIC, during the GSOC Mapping Global Training hosted by ISRIC - World Soil Information, 6 - 23 June 2017, Wageningen (The Netherlands).
What follows is a detailed discussion of each of the 20 AERs of India and the 60 AESRs with reference to this climate, soil and land use, the distinguishing features of the AESRs are also mentioned.
Paddy fields account for around 20% of human-related emissions of methane — a potent greenhouse gas. Farmers normally flood rice fields throughout the growing season, meaning that methane is produced by microbes underwater as they help to decay any flooded organic matter
How does agriculture, especially animal agriculture, impact greenhouse gas emissions? What is adaptation and mitigation and how are these different? For more materials on this topic visit http://www.extension.org/pages/63908/greenhouse-gases-and-animal-agriculture
Exploiting salt affected soils and poor quality waters for food security in I...ExternalEvents
Fifth Asian Soil Partnership workshop
26 February - 1 March 2019, New Delhi, India
Parbodh C. Sharma, ICAR - Central Soil Salinity Research Insititute, Karnal
soil organic carbon- a key for sustainable soil quality under scenario of cli...Bornali Borah
The global soil resource is already showing a sign of serious degradation (Banwart et al. 2014) which has ultimately negative impact on sustained crop yield and environmental quality. Due to intense rainfall and concurrent rise in temperature with changing climate, the fertile top soil is prone to severe degradation with depletion of SOC. Most soils in agricultural ecosystems have lost soil C ranging from 30 to 60 t C ha-1 with the magnitude of 50 to 75% loss (Lal, 2004). Hence, restoration of soil quality through different carbon management options will enhance soil health, mitigate climate change and provide sustained agricultural production.
The portion of a plant left in the field after harvest of the crop that is (straw, stalks, stems, leaves, roots) not used domestically or sold commercially”. The non – economical plant parts that are left in the field after harvest and remains that are generated from packing sheds or that are discarded during crop processing. Organic recycling has to play a key role in achieving sustainability in agricultural production. Multipurpose uses of crop residue include, but are not limited to, animal feeding, soil mulching, bio-manure, thatching of rural homes and fuel for domestic and industrial use. Thus, crop residues are of tremendous value to the farmers. Crop residue benefit the soil physically, chemically as well as biologically.
Land Use Changes on Soil Carbon Dynamics, Stocks in Eastern Himalayas, IndiaExternalEvents
This presentation was presented during the 2 Parallel session on Theme 2, Maintaining and/or increasing SOC stocks for climate change mitigation and adaptation and Land Degradation Neutrality, of the Global Symposium on Soil Organic Carbon that took place in Rome 21-23 March 2017. The presentation was made by Mr. Parmar Brajendra, from Indian Institute of Rice Research - India, in FAO Hq, Rome
Soil management strategies to enhance carbon sequestration potential of degra...koushalya T.N
Reclamation of degraded lands has huge potential for carbon (C) sequestration to counteract the climate change. It was estimated that about 1,964 Mha of land is degraded worldwide and in India 146.8 Mha of land is degraded ( Bai et al., 2008). The major land-degradation processes in the World and in Asia are water erosion, wind erosion, salinity, alkalinity, nutrient depletion and metal pollution. Enrichment of soil organic carbon (SOC) stocks through sequestration of atmospheric CO2 in agricultural soils and degraded lands is important because of its impacts on improving soil quality and agronomic production, and also for adaptation to mitigation of climate change. Various management strategies like conservation agriculture, integrated nutrient management, afforestation, alternate land use, plantations and amendments and use of biochar hold promise for long-term C sequestration. It can be concluded that land degradation is a serious problem in India which need to be tackled because shrinking of land resource base will lead to a substantial decline in food grain production which in turn would hamper the economic growth rate and there would also be unprecedented increase in mortality rate owing to hunger and malnutrition.
Conservation Agriculture (CA) is a concept for resource-saving agricultural crop production system that strives to achieve acceptable profits together with high and sustained production levels while conserving the environment.
It is based on minimum tillage, crop residue retention, and crop rotations, has been proposed as an alternative system combining benefits for the farmer with advantages for the society.
Conservation Agriculture remains an important technology that improves soil processes, controls soil erosion and reduces production cost.
Climate change, its impact on agriculture and mitigation strategiesVasu Dev Meena
According to IPCC (2007) “Climate change refers to a statistically significant variation in either the mean state of the climate or in its Variability, persisting for an extended period (typically decades or longer)”.
Climate change has adverse impacts on agriculture, hydropower, forest management and biodiversity.
In the long run, the climatic change could affect agriculture in several ways such as quantity and quality of crops in terms of productivity, growth rates, photosynthesis and transpiration rates, moisture availability etc.
Climate change directly affect food production across the globe.
Climate-Smart Agriculture Training for Practitioners
Asia Development Bank
9-11 October 2018, Tokyo, Japan
Session: Options for Mitigation in Agriculture
Presented by Lini Wollenberg, Low Emissions Development Flagship Leader, CGIAR Research Program on Climate Change, Agriculture and Food Security (CCAFS)
How does agriculture, especially animal agriculture, impact greenhouse gas emissions? What is adaptation and mitigation and how are these different? For more materials on this topic visit http://www.extension.org/pages/63908/greenhouse-gases-and-animal-agriculture
Exploiting salt affected soils and poor quality waters for food security in I...ExternalEvents
Fifth Asian Soil Partnership workshop
26 February - 1 March 2019, New Delhi, India
Parbodh C. Sharma, ICAR - Central Soil Salinity Research Insititute, Karnal
soil organic carbon- a key for sustainable soil quality under scenario of cli...Bornali Borah
The global soil resource is already showing a sign of serious degradation (Banwart et al. 2014) which has ultimately negative impact on sustained crop yield and environmental quality. Due to intense rainfall and concurrent rise in temperature with changing climate, the fertile top soil is prone to severe degradation with depletion of SOC. Most soils in agricultural ecosystems have lost soil C ranging from 30 to 60 t C ha-1 with the magnitude of 50 to 75% loss (Lal, 2004). Hence, restoration of soil quality through different carbon management options will enhance soil health, mitigate climate change and provide sustained agricultural production.
The portion of a plant left in the field after harvest of the crop that is (straw, stalks, stems, leaves, roots) not used domestically or sold commercially”. The non – economical plant parts that are left in the field after harvest and remains that are generated from packing sheds or that are discarded during crop processing. Organic recycling has to play a key role in achieving sustainability in agricultural production. Multipurpose uses of crop residue include, but are not limited to, animal feeding, soil mulching, bio-manure, thatching of rural homes and fuel for domestic and industrial use. Thus, crop residues are of tremendous value to the farmers. Crop residue benefit the soil physically, chemically as well as biologically.
Land Use Changes on Soil Carbon Dynamics, Stocks in Eastern Himalayas, IndiaExternalEvents
This presentation was presented during the 2 Parallel session on Theme 2, Maintaining and/or increasing SOC stocks for climate change mitigation and adaptation and Land Degradation Neutrality, of the Global Symposium on Soil Organic Carbon that took place in Rome 21-23 March 2017. The presentation was made by Mr. Parmar Brajendra, from Indian Institute of Rice Research - India, in FAO Hq, Rome
Soil management strategies to enhance carbon sequestration potential of degra...koushalya T.N
Reclamation of degraded lands has huge potential for carbon (C) sequestration to counteract the climate change. It was estimated that about 1,964 Mha of land is degraded worldwide and in India 146.8 Mha of land is degraded ( Bai et al., 2008). The major land-degradation processes in the World and in Asia are water erosion, wind erosion, salinity, alkalinity, nutrient depletion and metal pollution. Enrichment of soil organic carbon (SOC) stocks through sequestration of atmospheric CO2 in agricultural soils and degraded lands is important because of its impacts on improving soil quality and agronomic production, and also for adaptation to mitigation of climate change. Various management strategies like conservation agriculture, integrated nutrient management, afforestation, alternate land use, plantations and amendments and use of biochar hold promise for long-term C sequestration. It can be concluded that land degradation is a serious problem in India which need to be tackled because shrinking of land resource base will lead to a substantial decline in food grain production which in turn would hamper the economic growth rate and there would also be unprecedented increase in mortality rate owing to hunger and malnutrition.
Conservation Agriculture (CA) is a concept for resource-saving agricultural crop production system that strives to achieve acceptable profits together with high and sustained production levels while conserving the environment.
It is based on minimum tillage, crop residue retention, and crop rotations, has been proposed as an alternative system combining benefits for the farmer with advantages for the society.
Conservation Agriculture remains an important technology that improves soil processes, controls soil erosion and reduces production cost.
Climate change, its impact on agriculture and mitigation strategiesVasu Dev Meena
According to IPCC (2007) “Climate change refers to a statistically significant variation in either the mean state of the climate or in its Variability, persisting for an extended period (typically decades or longer)”.
Climate change has adverse impacts on agriculture, hydropower, forest management and biodiversity.
In the long run, the climatic change could affect agriculture in several ways such as quantity and quality of crops in terms of productivity, growth rates, photosynthesis and transpiration rates, moisture availability etc.
Climate change directly affect food production across the globe.
Climate-Smart Agriculture Training for Practitioners
Asia Development Bank
9-11 October 2018, Tokyo, Japan
Session: Options for Mitigation in Agriculture
Presented by Lini Wollenberg, Low Emissions Development Flagship Leader, CGIAR Research Program on Climate Change, Agriculture and Food Security (CCAFS)
Presentation by R Wassmann, International Rice Research Institute, at the CCAFS Workshop on Institutions and Policies to Scale out Climate Smart Agriculture held between 2-5 December 2013, in Colombo, Sri Lanka
"Rethinking Agriculture for the 21st Century: Climate change mitigation opportunities and challenges" was presented by Lini Wollenberg online at the KfW Webinar on May 28, 2020.
Farm-level options for accelerating the transition towards climate smart agri...CIAT
The difference between clever and smart people is mainly that clever people can get in and out of problems which smart people would not have gotten into in the first place. In the same light, faced with multifaceted challenges related to climate change, smartness would entail adapting our agricultural systems to avoid experiencing the negative impacts of climate change. In other words, climate smart agriculture (CSA) involves changing our agricultural systems to simultaneously address climate change challenges such as low food production, accelerated land degradation and increasing atmospheric concentrations of greenhouse gases. To achieve these objectives, agricultural systems should (1) sustainably increase productivity; (2) adapt and build resilience to climate change; and (3) reduce and/or avoid the emission of greenhouse gases. As will be discussed in this presentation, there is definitely no single agricultural technology or practice that can be universally applied to achieve these objectives. Nonetheless, site-specific assessments should be pursued to identify suitable agricultural practices, technologies, polices, financing and institutional arrangements that enhance smartness within a given situation. It will be noted that CSA is not necessarily based on new practices, technologies, polices and institutions. However, it involves holistically and simultaneously addressing challenges related to climate change by using a combination of familiar practices, technologies, polices and institutions in strategic but unfamiliar ways; that are not counterproductive. Moreover, the presentation aims to start a conversation on part of the work that has been done, is being done and can be done, through CIAT, to accelerate the transition towards smarter agriculture systems to ensure that, similar to smart people, we can avoid problems that complicate ours and the lives of generations to come.
Increasing the storage of carbon in the soil has been a controversial strategy for addressing climate change mitigation. What is the potential and why is there debate about this? How can we push beyond the debate to constructive action?
Lini Wollenberg, a Gund Fellow, is an anthropologist and natural resource management specialist concerned with rural livelihoods and the environment. She currently leads a research program on Low Emissions Agricultural Development for the CGIAR Research Program on Climate Change, Agriculture and Food Security (CCAFS), based at the University of Vermont. Her work seeks to identify options for reducing the impacts of agricultural development and land use on the climate, while also improving livelihoods for the poor in developing countries.
This presentation was given by Lini Wollenberg, CCAFS, on September 11, 2020 as part of the GundxChange Series.
This presentation was given as part of the EPA-funded Catchment Science and Management Course focusing on Integrated Catchment Management, held in June 2015. This course was delivered by RPS Consultants. If you have any queries or comments, or wish to use the material in this presentation, please contact catchments@epa.ie
It is increasingly being recognised internationally that integrated catchment management (ICM) is a useful organising framework for tackling the ongoing challenge of balancing sustainable use and development of our natural resource, against achieving environmental goals. The basic principles of ICM (Williams, 2012) are to:
• Take a holistic and integrated approach to the management of land, biodiversity, water and community resources at the water catchment scale;
• Involve communities in planning and managing their landscapes; and
• Find a balance between resource use and resource conservation
ICM is now well established in Australia, New Zealand, and the United States. In Europe the ICM approach has been proposed as being required to achieve effective water and catchment management, and is the approach being promoted by DEFRA for the UK, where it is called the “Catchment Based Approach” (CaBA). The principles and methodologies behind ICM sit well within the context of the Water Framework Directive with its aims and objectives for good water quality, sustainable development and public participation in water resource management. In Ireland it is proposed that the ICM approach will underlie the work and philosophy in developing and implementing future River Basin Management Plans.
Presentation at workshop: Reducing the costs of GHG estimates in agriculture to inform low emissions development
November 10-12, 2014
Sponsored by the CGIAR Research Program on Climate Change, Agriculture and Food Security (CCAFS) and the Food and Agriculture Organization of the United Nations (FAO)
Status and challenges for mapping, monitoring and MRV of SOCFAO
This presentation was presented during the Plenary 1, GSOC17 – Setting the scientific scene for GSOC17 of the Global Symposium on Soil Organic Carbon that took place in Rome 21-23 March 2017. The presentation was made by Mr. Martial Bernoux from FAO, in FAO Hq, Rome
Low Emissions Development Strategies (LEDS) Training Sept 9, 2013IFPRI-EPTD
Globally, agriculture is responsible for 10 – 14% of GHG emissions and largest source of no-CO2 GHG emissions. Countries can choose among a portfolio of growth-inducing technologies with different emission characteristics. We believe that is less costly to avoid high-emissions lock-in than replace high-emissions technologies. There's a need to encourage Low Emission Development Strategies.
"Challenges, opportunities and priorities for transitioning to low emissions agriculture" was presented by Lini Wollenberg at a NUI Galway seminar on January 30, 2020.
Similar to GHG mitigation potential in rice production (20)
The Accelerating Impact of CGIAR Climate Research for Africa (AICCRA) project works to deliver a climate-smart African future driven by science and innovation in agriculture.
AICCRA does this by enhancing access to climate information services and climate-smart agricultural technology to millions of smallholder farmers in Africa.
With better access to climate technology and advisory services—linked to information about effective response measures—farmers can better anticipate climate-related events and take preventative action that help communities better safeguard their livelihoods and the environment.
AICCRA is supported by a grant from the International Development Association (IDA) of the World Bank, which is used to enhance research and capacity-building activities by the CGIAR centers and initiatives as well as their partners in Africa.
About IDA: IDA helps the world’s poorest countries by providing grants and low to zero-interest loans for projects and programmes that boost economic growth, reduce poverty, and improve poor people’s lives.
IDA is one of the largest sources of assistance for the world’s 76 poorest countries, 39 of which are in Africa.
Annual IDA commitments have averaged about $21 billion over circa 2017-2020, with approximately 61 percent going to Africa.
This presentation was given on 27 October 2021 by Mengpin Ge, Global Climate Program Associate at WRI, during the webinar "Achieving NDC Ambition in Agriculture" organized by CCAFS, FAO and WRI.
Find the recording and more information here: https://bit.ly/AchievingNDCs
This presentation was given on 27 October 2021 by Sabrina Rose, Policy Consultant at CCAFS, during the webinar "Achieving NDC Ambition in Agriculture" organized by CCAFS, FAO and WRI.
Find the recording and more information here: https://bit.ly/AchievingNDCs
This presentation was given on 27 October 2021 by Krystal Crumpler, Climate Change and Agricultural Specialist at FAO, during the webinar "Achieving NDC Ambition in Agriculture" organized by CCAFS, FAO and WRI.
Find the recording and more information here: https://bit.ly/AchievingNDCs
This presentation was meant to be included in the 2021 CLIFF-GRADS Welcome Webinar and presented by Ciniro Costa Jr. (CCAFS).
The webinar recording can be found here: https://youtu.be/UoX6aoC4fhQ
The multilevel CSA monitoring set of standard core uptake and outcome indicators + expanded indicators linked to a rapid and reliable ICT based data collection instrument to systematically
assess and monitor:
- CSA Adoption/ Access to CIS
- CSA effects on food security and livelihoods household level)
- CSA effects on farm performance
Presented by Harsh Rajpal, Code Partners Pte. Ltd., on 30 June 2021 at the Asian Development Bank (ADB) Webinar on Sustainable Protein Case Study: Outputs and Synthesis of Results.
Presented by Ciniro Costa Jr., CCAFS, on 28 June 2021 at the Asian Development Bank (ADB) Webinar on Sustainable Protein Case Study: Outputs and Synthesis of Results.
Presented by Marion de Vries, Wageningen Livestock Research at Wageningen University, on 28 June 2021 at the Asian Development Bank (ADB) Webinar on Sustainable Protein Case Study: Outputs and Synthesis of Results.
Presented by Issac Emery, Informed Sustainability Consulting, on 29 June 2021 at the second day of the Asian Development Bank (ADB) Webinar on Sustainable Protein Case Study: Outputs and Synthesis of Results.
Presented by Hongmin Dong and Sha Wei, Chinese Academy of Agricultural Sciences (CAAS), on 28 June 2021 at the Asian Development Bank (ADB) Webinar on Sustainable Protein Case Study: Outputs and Synthesis of Results.
Presented by Lini Wollenberg, CCAFS, on 28 June 2021 at the Asian Development Bank (ADB) Webinar on Sustainable Protein Case Study: Outputs and Synthesis of Results.
Presentation by Han Soethoudt, Jan Broeze, and Heike Axmann of Wageningen University & Resaearch (WUR).
WUR and Olam Rice Nigeria conducted a controlled experiment in Nigeria in which mechanized rice harvesting and threshing were introduced on smallholder farms. The result of the study shows that mechanization considerably reduces losses, has a positive impact on farmers’ income, and the climate.
Learn more: https://www.wur.nl/en/news-wur/show-day/Mechanization-helps-Nigerian-farms-reduce-food-loss-and-increase-income.htm
Presentation on the rapid evidence review findings and key take away messages.
Current evidence for biodiversity and agriculture to achieve and bridging gaps in research and investment to reach multiple global goals.
This presentation was given at an internal workshop in April 2020 and was presented by Le Hoang Anh, Hoang Thi Thien Huong, Le Thi Thanh Huyen, and Nguyen Thi Lien Huong.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Comparative structure of adrenal gland in vertebrates
GHG mitigation potential in rice production
1. Mitigation potential in rice production
Reiner Wassmann
Bjoern Ole Sander
International Rice Research Institute
2. Outline
• Background: Rice as a source of GHGs
• Possible Options for Mitigation in Rice
• Feasibility assessment for
Alternate-Wetting-and-Drying
• Outlook and Conclusion
3. Significance of Rice Fields for GHG budgets
Forestry,
17.4%
Rice, 1.5%
Agriculture
(w/o rice),
12.0%
(IPCC 4th AR, 2007)
All others ,
69.1%
Country
National Scale in Asia:
Emissions from rice
production
Percentage of total
Vietnam 24.8 %
Bangladesh 7.2 %
Colombia 0.8 %
Data from the most 2nd National
Communication of respective country
4. Greenhouse Gas Emissions from Rice
Nitrous Oxide
Emissions from
Fertilizer
Application
Methane emissions: 100 – 500 kg CH4/ ha season
=> 2 – 12 tCO2eq/ ha season
7. Outline
• Background: Rice as a source of GHGs
• Possible Options for Mitigation in Rice
• Feasibility assessment for
Alternate-Wetting-and-Drying
• Outlook and Conclusion
8. Impact of Mid-season Drainage
on Methane Emissions
water level (cm) / line Eh (mV) / dots
100
0
Continuous Flooding -100
Mid-season Drainage
-200
water level (cm) / line Eh (mV) / dots
30
20
10
1400
1200
1000
800
600
400
200
Days after planting
30
20
10
0
20 40 60 80 100 120
-300
1400
1200
1000
800
600
400
200
0
methane emission (mg CH4 m-2 d-1)
20 40 60 80 100 120
0
20 40 60 80 100 120
100
0
-100
-200
-300
0
methane emission (mg CH4 m-2 d-1)
20 40 60 80 100 120
Field experiment at Hangzhou, China (Wassmann et al., 2000)
10. AWD Experiment in Central Vietnam
Rice,
Maize,
Peanut...
Rice,
Maize…
Ha Noi
HCM City
Minh et al. (in prep.)
11. Results from Field Measurements
Measured Data
supplied
by Hoa et al.
Delta Lowland
8.0
7.0
6.0
5.0
4.0
3.0
2.0
1.0
18
16
14
12
10
8
6
4
2
0
20 30 40 50 60 70 80 90 100 110
DAT
kg CH4/ha/day
CF Measured
CF Simulated
AWD Measured
AWD Simulated
Hilly Midland
0.0
20 30 40 50 60 70 80 90 100 110
DAT
kg CH4/ha/day
CF Measured
CF Simulated
AWD Measured
AWD Simulated
12. New Policy on Mitigation in Agricultural Sector in VN
From national level…
to implementation at provincial level.
Farmers should use/apply
AWD irrigation technology to
not only greatly save water
consumption and reduce
GHGs emissions in irrigated
rice fields, but also increase
rice productivity.
20-20-20
Decision
AWD is directly mentioned as one
mitigation option by Ministry of
Agriculture
13. Mitigation through Optimized
Fertilizer Applications
Farmers need to know
• Correct timing…
• Correct amounts…
• Correct sources…
… of fertilizer applications
Rice fields are typically
small and can substantially
differ from each other
14. Operation of Mobile Phone App
Provide
management
recommen-dation
Cloud based server
Rice Crop Manager
• Nutrients
• Weeds
• Irrigation
• ….
Obtain site-specific
information from
farmer/ operator
New Modules
• GHG emission
calculator
• Climate-adjusted
yield targets
Climate-Informed Rice Crop and Low Emission Manager
=> CIRCLE Manager
15. Outline
• Background: Rice as a source of GHGs
• Possible Options for Mitigation in Rice
• Suitability assessment for
Alternate-Wetting-and-Drying
• Outlook and Conclusion
16. AWD projects in the Philippines (Central Luzon)
Angat Irrigation
(AMRIS): B1; B2
22. Lessons learned in case studies
• Stress the co-benefits of AWD (such as stronger
lodging resistance) to motivate farmers to adopt
• Focus on ‘tail-end’ farmers to showcase the
feasibility of AWD
• Offer alternative irrigation options -- from single
drainage to full AWD
• Try to identify local ‘champions’ for technology
adoption
• Include irrigation authorities right from the onset
of the project
23. Assist in Carbon Crediting?
Small Scale Methodology Approved by UNFCCC (May 2011):
“Methane emission
reduction by adjusted
water management in rice”
http://cdm.unfccc.int/methodologies/DB/D6MRRHNNU5RUHJXWKHN87IUXW5F5N0/view.html
25. Methodology AMS-III.AU.
Version 3.0 (since 03 Aug. 2012)
Example:
• AWD in dry season
• Multiple aeration (1.8 kg ha/d)
• 100 d period
180 kg CH4/ ha season
= 3.78 t CO2 eq/ ha season
@ 0.50 $/ t CO2 eq.
= < 2 $/ ha season
26. Good Agricultural Practice
(GAP) Guidelines
Vietnam
Mot Phai/
Nam Giam
(1 Must Do/
5 Reductions)
Philippines
Palay
Check
Examples:
27. Outline
• Background: Rice as a source of GHGs
• Possible Options for Mitigation in Rice
• Feasibility assessment for
Alternate-Wetting-and-Drying
• Outlook and Conclusion
28. New Project:
“Mitigation Options to
Reduce Methane
Emissions in Paddy Rice”
CCAC:
• Partnership of governments, inter-governmental
organizations, private sector (40 governments,
53 non-state entities)
• Mission: Fight global warming and improve human
health
• Focus on SLCP (short-lived climate pollutants)
• Operates under UNEP
29. CCAC initiatives
3 components
• Open Agricultural Burning
• Livestock/ Manure Management
• Paddy Rice Production
30. New Project:
“Mitigation Options to
Reduce Methane
Emissions in Paddy Rice”
Overall Objective:
Road maps for implementing replicable
and scalable mitigation options focussing
on AWD in 3 target countries:
Vietnam
Bangladesh
Colombia
31. New Project:
“Mitigation Options to
Reduce Methane
Emissions in Paddy Rice”
Specific Objectives:
1) Improved information platforms
2) National networks, enhanced capacity
and plans
3) Pilot studies in areas with AWD
experience for extracting ‘lessons learnt’
32. Conclusions
Policy makers are getting increasingly
interested to integrate mitigation into
development targets
… BUT …
different stakeholders will need
diversified information packages and
decision support tools
33. Conclusions
Scientific findings and publications will
NOT be sufficient as such to stimulate
mitigation
… BUT …
should be translated into clear spatial
and temporal priorities at different
scales