GENERAL EXAMINATION OF CARDIAC PATIENTS:
Conscious level and mentality.
Appearance
Built
Complexion
Decubitus
Vital signs: (pulse, BP, Temperature, R.R.)
U.L & L.L.
Head & Neck
Other system review; Chest, Abdomen , Neurological, …
Summary flowchart for CVS EXAMINATION.
Brief Presentation on clinical examination of Cardio Vascular System with Report of Normal case
references:
macleod's clinical examination 13th edition
hutchinson clinical methods
Brief Presentation on clinical examination of Cardio Vascular System with Report of Normal case
references:
macleod's clinical examination 13th edition
hutchinson clinical methods
Cardiology 1.1. Chest pain - by Dr. Farjad IkramFarjad Ikram
Introduction to one of the most common symptoms that can represent a wide range of diseases, from benign to life-threatening, covering number of systems including gastrointestinal, cardiovascular, pulmonary, musculoskeletal and psychiatric. Includes a brief explanation of anti-anginal therapy.
Template design credits - http://www.slidescarnival.com
Cardiology 1.1. Chest pain - by Dr. Farjad IkramFarjad Ikram
Introduction to one of the most common symptoms that can represent a wide range of diseases, from benign to life-threatening, covering number of systems including gastrointestinal, cardiovascular, pulmonary, musculoskeletal and psychiatric. Includes a brief explanation of anti-anginal therapy.
Template design credits - http://www.slidescarnival.com
Side effects of commonly prescribed drugs:
Diuretics
NSAIDs.
Antiplatelet.
Corticosteroids.
Drug induced Hemolytic Anemia.
Lipid lowering agents.
Anticoagulants
Iron
Topics Covered:
Basic kidney physiology (just enumeration).
Manifestations of renal impairment.
AKI vs. CRF , definitions, causes and their classifications (in brief) .
Clinical evaluation of a case of renal failure.
indications for renal replacement therapy.
Approach for real-Life patient with renal impairment: group-case discussion.
Glomerulonephritis: History taking and examination.Ahmed Redwan
The history, and physical examination
aimed at :
Clinical differentiation of major nephrological syndromes.
Establishing possible cause(s).
Finding evidence of associated multisystem disease
Excluding confounding non-glomerular disease (e.g. urological)
Evaluation & grading renal function.
Estimate complication (s)
Report previous management to which the patient was subjected to and its outcome.
Dialysis principal, modalities, its role as renal replacement therapy (R.R.T.).
Indications for dialysis, other R.R.T. options how to choose, and their limitations.
HD technique, terminology; e.g. dry weight, U.F., Dialysis prescription, Dialysis adequacy.
HD monitoring, complications, management.
HD session case management.
Best Ayurvedic medicine for Gas and IndigestionSwastikAyurveda
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
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Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
2. Topics Discussed:
Conscious level and mentality.
Appearance
Built
Complexion
Decubitus
Vital signs: (pulse, BP, Temperature, R.R.)
U.L & L.L.
Head & Neck
Other system review; Chest, Abdomen ,
Neurological, …
Summary flowchart for CVS EXAMINATION.
3. Conscious level and mentality.
Intellectual functions with cloudy mentality may be affected
with generalized atherosclerosis that also may lead to
Transient ischemic attack (T.I.A).
Embolic manifestations : M.S ,A.F. leads to Cerebral Stroke.
Hypertensive Encephalopathy (e.g. Posterior reversible
encephalopathy Syndrome (PRES) and cerebral Hge->Fits).
Pulmonary edema also affects the patient consciousness
especially after development of Respiratory Failure (hypoxia
+/- hypercapnia)
Disease Association CVS + NS:
Fridriech’s ataxia with Cardiomyopathy
Parkinson’s disease with primary orthostatic hypotension + syncope.
6. Cachexia
Cachexia refers to severe muscle and
fat loss, anorexia and marked weight
loss due to an underlying chronic
disease condition leading to lower life
expectancy.
The title cachexia, from the Greek
kakos (i.e., bad) and hexis (i.e.,
condition or appearance), or 'bad
condition‘.
7. Cachexia D.D.
Cachexia is a serious and underestimated
consequence in many conditions:
Cancer
Organ failure
Chronic conditions like chronic heart failure,
chronic kidney disease, chronic obstructive
pulmonary disease
Infectious diseases like tuberculosis, acquired
immunodeficiency syndrome(AIDS)
Inflammatory disorders like rheumatoid
arthritis
8. Built
1.Height:
Marfan's syndrome: (Tall+arachnodactyly+pes-
cavas-high arched palate+ ectopia lentis) dissecting
aortic aneurysm, aortic incompetence and MVP.
2.Dwarf undergrowth: Congenital heart disease or
in long standing heart disease since childhood.
2.Weight (BMI):
Underweight: Prolonged heart disease whatever
congenial or rheumatic.
Overweight: Atherosclerosis, HTN, MI.
3. Well developed upper part and under
developed lower part in coarctation of the aorta.
22. Jaundice:
Causes of jaundice in a cardiac patient:
1. Hemolytic J.: in pulmonary infarction, artificial
valves.
2. Hepato-cellular J.: in marked hepatic
congestion (cardiac cirrhosis)due to severe Rt.
sided HF - pericardial effusion -TS & TR.
3. Obstructive J.: bile & inspissation of bile in
canalicular lumen.
4. Associated viral hepatitis: the Commonest !!.
23.
24. Cyanosis
1. Central: Congenital cyanotic heart
disease (F4)- Advanced heart failure.
2. Peripheral: L.C.O.P., C.H.F., Peripheral
vascular disorders.
3. False (chemical) cyanosis:
Methemoglobinemia in nitrate ttt.
4. N.B.: "differential cyanosis": Means
cyanosis more apparent in lower part of
the body in reversed P.D.A.
29. Temperature
Fever in CVS:
IE
Rh.Fever
Chest infection
Pericarditis
Myocard. Infarction & pulm. Embolism
DVT and thrombophlepitis
Associated fever
30. Pulse:
Feel the right radial artery to
determine, pulse rate , rhythm, volume,
character equality (volume) in both upper
limbs, radiofemoral delay (Aortic
coarctation) and state of arterial wall.
One should also examine all
peripheral pulses in the carotides
brachial,femorals, post. tibial and dorsalis
pedis as routine specially in cardiac cases
with history of embolization.
40. R.R.
Tachypnea:
Pulm edema
H.F, MI, pulm. embolism
Associated chest infection.
Complication: Resp. Failure.
Distressed sweaty or clammy
('diaphoretic') Acute MI
41. Upper Limb
• 1-Dorsal aspect of the hands:
Tobacco "tar" staining
Peripheral cyanosis.
Temperature.
Clubbing(cyanotic HD or toxic I.E.)
I.E. THROMBOEMBOLC MANIFESTATIONS:
Splinter haemorrhages (linear, reddish brown marks along the
axis of the finger and to nails, thought to be due to circulating
immune complexes).
Jenway’s lesions
Oslar’s nodules
• Sc nodules
• Arthritis due to Rheumatic fever.
• Abnormal movement (chorea)
• Xanthomatas around tendons
42. Upper Limb
• 1-Dorsal aspect of the hands:
Tobacco "tar" staining
Peripheral cyanosis.
Temperature.
Clubbing(cyanotic HD or toxic I.E.)
I.E. THROMBOEMBOLC MANIFESTATIONS:
Splinter haemorrhages (linear, reddish brown marks,
multiple >2, along the axis of the finger and to nails,
thought to be due to circulating immune complexes).
Jenway’s lesions
Osler’s nodules
• Sc nodules (Rh. Fever).
• Arthritis due to Rheumatic fever.
• Abnormal movement (chorea) H.F.
• Xanthomatas around tendons
43. Upper Limb
2-Palmar aspect of the hands:
• Janeway lesions - painless red spots/macules, which blanch on
pressure, on the thenar/hypothenar eminences of the Palms, and
soles of the feet.
• Osler's nodes – small painful raised erythematous lesions
(nodules) which are rare but found most often on the pads of the
fingers (finger pulps) And toes representing digital microinfarction.
3-Palmar and extensor surfaces of the hands:
xanthomata (yellow skin or tendon nodules from lipid deposits).
4-Entire skin surface: petechiae.
60. Neck
Neck veins: venous waves and venous
pressure (Congestion) by examination of the
internal jugular vein (the window of the right
atrium).
Normally there is no congestion , but only normal
pulsation.
Thrill: Palpate the neck for thrill.
Causes:
A.S.Thyrotoxicosis, Aneurysm of carotid artery.
65. Abdomen
C-ABDOMINAL EXAMINATION:
1-Liver:-Enlarged & tender in: RVF,
pericardial disease-Enlarged, tender with
expansile pulsation: TR. TS-Enlarged firm,
with sharp border: cardiac cirrhosis
2-Spleen: enlarged in RVF, pericardial
disease3-Ascites: after edema in RVF, or
ascites precox in TR. TS. Pericardial
diseas.
66. BACK EXAMINATION:
1) Murmurs: - Bruit:of MR left scapolar regionOf coarctation
of aorta: interscapular region -Bnist of renal artery
stenosis in renal angle.
2) Crepitations:-Bilateral basal crepitation: LVF-Bubbling
coarse crepitations pulmonary edema
3) Ewart's sign: collapse of left lower lobe in pericardial
effusion
4) Vertebrae - Scapula:-Spina bifida: associated congenital
anomaly in congenital HD-Low back pain, stiffness &
limited spine mobility m ankylosing spondylitis
associated with AR -Anastomosis around scapula in
coarctation of aorta
5) Skin: Cafe au lait patches in neurofibromatosas
associated with pheochromocytoma & IHSS.
6) Sacral edema: pitting edema at sacral area in prolonged
bed ridden patients with Heart failure.