Gamma knife in posterior third ventricular tumors
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1) The study evaluated the effectiveness of gamma knife (GK) surgery as primary or adjuvant treatment for posterior third ventricular tumors in 17 patients over 12 years. 2) Tumor control was achieved in 13 of 14 patients (92.8%) with an average follow up of 31 months, with 7 patients showing tumor reduction and 6 showing no change. 3) Primary GK achieved 100% tumor control for benign diseases and showed good control of malignant pinealoblastomas and metastases for up to 27 months.
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Gamma knife in posterior third ventricular tumors
- 1. Vikas Naik, Deepak Agrawal, SS Kale, MS Sharma, BS Sharma, AK Mahapatra Department of Neurosurgery & Gamma-Knife surgery, All India Institute of Medical Sciences, New Delhi
- 16. 12/18/2009 NSI-2009 Diagnosis Histology proven MRI based Csf diversion Adjuvant RT Adjuvant CT Meningiomas (8) 4 4 1 0 0 Pineal tumors (4) 3 1 3 1 1 Gliomas (3) 2 1 1 1 0 PNET (1) 1 0 1 0 1 Metastasis (1) 0 1 0 0 0 Total (17) 10 7 6 2 2
- 20. 12/18/2009 NSI-2009 Symptom No of patients in Primary GK No of patients in Secondary GK Percentage HEADACHE 4 4 47 ASYMPTOMATIC 4 1 29.4 VOMITING 1 2 17.6 HEMIPARESIS 1 2 17.6 DROOPING OF EYELID 1 1 11.76 SEIZURES 1 0 5.8 MEMORY IMPAIRMENT 1 0 5.8 GAIT ATAXIA 1 0 5.8 URINARY INCONTINIENCE 1 0 5.8 DIPLOPIA 1 0 5.8
- 21. 12/18/2009 NSI-2009 SIGNS No of patients of Primary GK No of patients of secondary GK PERCENTAGE NO DEFICITS 5 3 47 HEMIPARESIS 1 3 23.5 PAPILLOEDEMA 2 1 17.6 PARINAUDS 1 1 11.76 SEVENTH NERVE 1 1 11.76 THIRD NERVE 1 1 11.76 RECENT MEMORY 1 0 5.8 NYSTAGMUS 0 1 5.8
- 23. SECONDARY GK 12/18/2009 NSI-2009 Diagnosis Follow up period (months) Tumor volume (cm3) Radiation iso dose (Gy) Tumor control Worsening Beningn Meningiomas 54 12.5 12.52 4/4 - Gliomas 4 6.25 16 1/1 - Malignant Pinealoblastoma 9 1.4 24 1/1 - PNET 25 3.2 16 1/1 -
- 24. Pinealocytoma at GK Pinealocytoma post 24 months GK 12/18/2009 NSI-2009
- 25. Meningioma at GK Meningioma after 75 months GK 12/18/2009 NSI-2009
- 26. Pinealoblastoma Pre- Operative 12/18/2009 NSI-2009
- 27. At GK planning Pinealoblastoma 9 month after GK 12/18/2009 NSI-2009