Bacteria provide many benefits in various industries and natural processes. They are used in food processing to make bread, yogurt, cheese, and fermented foods. In biotechnology, bacteria produce chemicals, enzymes, dietary supplements, and pharmaceuticals. Genetic engineering uses bacteria to produce important products like human insulin. Bacteria also help separate plant fibers, control pests biologically, remove pollutants from the environment through bioremediation, aid digestion in animals, tan leather, and create antibiotics and vaccines.
Role of bacteria in Industry and MedicineRitaSomPaul
It describes positive and negative roles of bacteria in Industry and Medicine. It is a part of Microbiology syllabus in Botany (Hons) as per CBCS system
Economic importance of bacteria
#Economic importance of bacteria
#Bacteria : economically important as these microorganisms are used by humans for many purposes.
#Beneficial uses of bacteria
#Genetic engineering :
#Biotechnology :
#Food processing :
#Bioremediation
#Industry importance of bacteria
#Fiber industry:
#Medicine (probiotics)
#Agriculture importance
Role of bacteria in Industry and MedicineRitaSomPaul
It describes positive and negative roles of bacteria in Industry and Medicine. It is a part of Microbiology syllabus in Botany (Hons) as per CBCS system
Economic importance of bacteria
#Economic importance of bacteria
#Bacteria : economically important as these microorganisms are used by humans for many purposes.
#Beneficial uses of bacteria
#Genetic engineering :
#Biotechnology :
#Food processing :
#Bioremediation
#Industry importance of bacteria
#Fiber industry:
#Medicine (probiotics)
#Agriculture importance
Microbes are diverse – protozoa, bacteria, fungi and microscopic plants viruses, viroids and also prions (proteinocious infectious agents)
Its a view of some useful and harmful Microbes.
Bacteria are described in two ways:
Bergey’s Manual of Determinative Bacteriology.
Bergey’s Manual of Systematic Bacteriology.
The bacterial classification is based on 16S RNA sequences
Carl Woese, Oganizes the Domain Bacteria into 18 phyla
Bacterial phyla used in industrial microbiology and biotechnology
It discuss about what is microbes, types of microbes, where its founds, why it plays important in human life, main functions like agriculture, industry and medicines.
Microbes are diverse – protozoa, bacteria, fungi and microscopic plants viruses, viroids and also prions (proteinocious infectious agents)
Its a view of some useful and harmful Microbes.
Bacteria are described in two ways:
Bergey’s Manual of Determinative Bacteriology.
Bergey’s Manual of Systematic Bacteriology.
The bacterial classification is based on 16S RNA sequences
Carl Woese, Oganizes the Domain Bacteria into 18 phyla
Bacterial phyla used in industrial microbiology and biotechnology
It discuss about what is microbes, types of microbes, where its founds, why it plays important in human life, main functions like agriculture, industry and medicines.
These are the notes of an important chapter of class 12 biology , microbes in human welfare . These are absolutely sufficient for your preparation for board examinations .
Highly descriptive and illustrative presentation based on Biotechnology chapter 12 of NCERT class XII.
This is an important topic especially from biological research point of view.
This is to help students thoroughly understand the topic for exams as well as for future practical applications.
Microorganism and principle of biology,Medical microbiology and immunology,Soil microbiology,Industrial microbiology,Food microbiology,Water microbiology,Sewage microbiology
What is Healthcare?How Healthcare delivered ?Types of Healthcare:(i) Primary Healthcare:
(ii) Secondary Healthcare:
(iii) Tertiary Healthcare:
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Eid ul Adha necessary health precautions to keep in mind,1. Red Meat consumption in Eid ul Adha,2. Lessen fried items intake,3. Avoid frizzy drinks,4. Increase consumption of Fruits and Salads,5. Walking routine during Eid ul Adha.
What is Bushfire ?Bushfires in Australia,Why are there bushfires in Australia?What conditions lead to extreme fire weather?Victorian Bushfires fast facts,What causes bushfires?Why do bushfires spread?What controls fire behaviour?
Types of data sampling,probability sampling and non-probability sampling,Simple random sampling,Systematic sampling,Stratified sampling,Clustered sampling,Convenience sampling,Quota sampling,Judgement (or Purposive) Sampling,Snowball sampling,Bias in sampling.
Identification of Indian Major Carps,Catla catla (catla), Labeo rohita (rohu) and Cirrhinus cirrhosus (mrigal),Chinese Major carps , Grass, silver, bighead, and black carp , OTHER COMMON SPECIES OF PAKISTAN, Trout, Salmon, Tilapia
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
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Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
3. Contents
Food processing
Biotechnology
Genetic engineering
Fibre retting
Pest control
Bioremediation
Digestion
Tanning Of Leather
Medicines
4. Food processing
Sourdough bread is made to rise by fermentation, with
a leaven that consists of bacteria, often combined with wild
yeast enzymes.The milk-souring bacterial
genus Lactobacillus is used to make yogurt and cheese.
Bacteria are also used to form organic acids
in pickles and vinegar.
5. Biotechnology
Biotechnology involves the use of microorganisms including
bacteria and fungi in the manufacturing and services
industries.
These include chemical manufacturing such
as ethanol, acetone, organic acid, enzymes, and perfumes.
Bacteria are important in the production of many dietary
supplements and pharmaceuticals
6.
7. Cont…..
. For example, Escherichia coli is used for commercial
preparation of riboflavin and vitamin K. E. coli is also used to
produce D-amino acids such as D-p-hydroxyphenylglycine,
an important intermediate for synthesis of the
antibiotic amoxicillin.
8. Genetic engineering
Genetic engineering is the manipulation of genes. It is also
called recombinant DNA technology. In genetic engineering,
pieces of DNA (genes) are introduced into a host by a variety
of techniques, one of the earliest being the use of a virus
vector.
The foreign DNA becomes a permanent feature of the host,
and is replicated and passed on to daughter cells along with
the rest of its DNA.
9. Cont….
Bacterial cells are transformed and used in production of
commercially important products.
Examples include production of human insulin (used to treat
diabetes) and human growth hormone (somatotrophin used
to treat pituitary dwarfism).
10.
11. Fibre retting
Bacteria such as Clostridium butyricum are used to separate
fibres of jute, hemp and flax in the process of retting.
The plants are immersed in water and when they swell,
inoculated with bacteria which hydrolyze pectic substances
of the cell walls and separate the fibres. Alternatively, the
plants are spread out on the ground and ret naturally
because dew provides moisture.These separated fibres are
used to make ropes, sacks etc.
12. Cont…
Bacteria can also be used in the place
of pesticides in biological pest control.
This commonly uses Bacillus thuringiensis (also called BT), a
Gram-positive, soil-dwelling bacterium.This bacterium is
used as a Lepidopteran-specific insecticide under trade
names such as Dipel andThuricide. Because of their
specificity, these pesticides are regarded as environmentally
friendly, with little effect on humans, wildlife, pollinators, or
other beneficial insects.
13. Bioremediation
Bacteria can be used to remove pollutants from
contaminated water, soil and subsurface material.
During the Mega Borg Oil Spill, for example, 100 pounds of
bacteria were sprayed over an acre of the oil slick to break
down the hydrocarbons present into more benign by-
products.
14.
15. Digestion
Bacteria living in the gut of cattle, horses and other
herbivores, for example Ruminococcus spp., help
digest cellulose by secreting the enzyme cellulase.This is
how herbivores are able get the energy they need from grass
and other plants.
Also, Escherichia coli, part of the intestinal microbiota of
humans and other herbivorous animals, converts consumed
food into vitamin K2.This is absorbed in the colon and,
in animal models, is sufficient to meet their daily requirement
of the vitamin.
16. Tanning Of Leather
Bacteria helps purify animal hides to make them easy, clean,
and fit for use.
17. Medicines
Bacteria are used to create multiple antibiotics such as
Streptomycin from the bacteria streptococcus. Bacteria can
also be used to create vaccines to prevent several diseases.