The document discusses the fundamental components and structure of cells. It explains that cells contain organelles like the plasma membrane, nucleus, and cytoplasm. The plasma membrane is selectively permeable and allows movement of substances in and out of the cell through diffusion and osmosis. Osmosis is the movement of water across the plasma membrane from high to low concentration areas until equilibrium is reached. Solutions can be hypotonic, isotonic, or hypertonic depending on their concentration of water compared to the cell. Plant cells also contain a cell wall that provides structure and allows the cell to withstand changes in water concentration without bursting.
The Fundamental Unit Of Life Class - 9NehaRohtagi1
This PowerPoint Presentation will help the students of Class - 9 to understand that How a Cell Divides and the Organization Of Nucleas and so on. This Slide Presentation will clear your doubts and help you to score good marks in the examinations.
NCERT Solutions | Class IX | Science (Biology) | Chapter 5 | The Fundamental ...Biswarup Majumder
NCERT Solutions for Class 9 Biology is available in PDF format which you can download easily. Here is the most accurate and detailed Biology NCERT solutions for Class 9th CBSE textbook for free of cost.
I hope this document is helpful to you. Please share the document with your friends if you think this will benefit them. Get ready for the next solution. Thanks.
The Fundamental Unit Of Life Class - 9NehaRohtagi1
This PowerPoint Presentation will help the students of Class - 9 to understand that How a Cell Divides and the Organization Of Nucleas and so on. This Slide Presentation will clear your doubts and help you to score good marks in the examinations.
NCERT Solutions | Class IX | Science (Biology) | Chapter 5 | The Fundamental ...Biswarup Majumder
NCERT Solutions for Class 9 Biology is available in PDF format which you can download easily. Here is the most accurate and detailed Biology NCERT solutions for Class 9th CBSE textbook for free of cost.
I hope this document is helpful to you. Please share the document with your friends if you think this will benefit them. Get ready for the next solution. Thanks.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
2. What is a Cell Made Up of? What is
the Structural Organisation of a Cell?
The cell has special components called organelles.
How is a cell organised?
Almost every cell has plasma membrane, nucleus and cytoplasm. All
activities inside the cell and interactions of the cell with its
environment are possible due to these features.
Other covering and cell organelles are CELL WALL, RIBOSOME,
ENDOPLASMIC RETICULUM, GOLGI APPARATUS, LYSOSOMES,
MITOCHONDRIA, PLASTIDS, VACUOLES, CENTROSOME, CENTRIOLES etc.
3. This is the outermost covering of the cell that separates the contents
of the cell from its external environment. The plasma membrane
allows or permits the entry and exit of some materials in and out of
the cell. It also prevents movement of some other materials. The cell
membrane, therefore, is called a selectively permeable membrane.
How does the movement of substances take place into the cell?
How do substances move out of the cell?
Some substances like carbon dioxide or oxygen can move across the
cell membrane by a process called diffusion. There is spontaneous
movement of a substance from a region of high concentration to a
region where its concentration is low.
PLASMA MEMBRANE OR CELL
MEMBRANE
4. Some substance like CO2 (a cellular waste) accumulates in high
concentrations inside the cell. In the cell’s external environment, the
concentration of CO2 is low as compared to that inside the cell. As soon as
there is a difference of concentration of CO2 inside and outside a cell, CO2
moves out of the cell, from a region of high concentration, to a region of low
concentration outside the cell by the process of diffusion.
Similarly, O2 enters the cell by the process of diffusion when the level or
concentration of O2 inside the cell decreases. Thus, diffusion plays an
important role in gaseous exchange between the cells as well as the cell
and its external environment.
Water also obeys the law of diffusion. The movement of water molecules
through such a selectively permeable membrane is called osmosis.
ROLE OF DIFFUSION
5. The movement of water across the plasma membrane is also affected by the
amount of substance dissolved in water.
Thus, osmosis is the passage of water from a region of high water
concentration through a selectively permeable membrane to a region of low
water concentration till equilibrium is reached. (Endosmosis & Exosmosis)
What will happen if we put an animal cell or a plant cell into a solution of
sugar or salt in water?
HYPOTONIC SOLUTION
If the medium surrounding the cell has a higher water concentration (very
dilute) than the cell, the cell will gain water by osmosis. Such a solution is
known as a hypotonic solution.
Water molecules are free to pass across the cell membrane in both directions,
but more water will come into the cell than will leave. The net result is that water
enters the cell. The cell is likely to swell up.
ROLE OF OSMOSIS
6. ISOTONIC SOLUTION
If the medium surrounding the cell has exactly the same water concentration
as the cell, there will be no net movement of water across the cell membrane.
Such a solution is known as an isotonic solution.
Water crosses the cell membrane in both directions, but the amount going in is
the same as the amount going out, so there is no overall movement of water. The
cell will stay the same size.
HYPERTONIC SOLUTION
If the medium has a lower concentration of water (very concentrated ) than the
cell, the cell will lose water by osmosis. Such a solution is known as a
hypertonic solution.
Again, water crosses the cell membrane in both directions, but this time more
water leaves the cell than enters it. Therefore the cell will shrink.
Osmosis is a special case of diffusion through a selectively permeable
membrane.
7. (a) Remove the shell of an egg by dissolving it in dilute hydrochloric acid or
Vinegar. The shell is mostly calcium carbonate. A thin outer skin now
the egg. Put the egg in pure water and observe after 5 minutes. What do we
observe?
The egg swells because water passes into it by osmosis.
(b) Place a similar de-shelled egg in a concentrated salt or sugar solution and
observe for 5 minutes.
The egg shrinks. Why?
Water passes out of the egg solution into the salt or sugar solution because the
salt or sugar solution is more concentrated.
Note: Hypotonic, Hypertonic and Isotonic are comparative terms.
Activity - Osmosis with an egg
8. Put dried raisins or apricots in plain water and leave them for some time.
Then place them into a concentrated solution of sugar or salt.
You will observe the following:
(a) Each gains water and swells when placed in water.
(b) However, when placed in the concentrated solution it loses water, and
consequently shrinks.
Activity - Osmosis with Raisins or Apricots
Activit
y
Find out about electron microscopes from resources in the school library or
through the internet. Discuss it with your teacher.
9. Unicellular freshwater organisms and most plant cells tend to gain water through
osmosis. Absorption of water by plant roots is also an example of osmosis.
Thus, diffusion is important in exchange of gases and water in the life of a cell.
In additions to this, the cell also obtains nutrition from its environment. Different
molecules move in and out of the cell through a type of transport requiring use of
energy.
The plasma membrane is flexible and is made up of organic molecules called lipids
lipids and proteins.
The flexibility of the cell membrane also enables the cell to engulf in food and other
other material from its external environment. Such processes are known as
endocytosis. Amoeba acquires its food through such processes.
10. Plant cells, in addition to the plasma membrane, have another rigid outer
covering called the cell wall. The cell wall lies outside the plasma membrane. The
The plant cell wall is mainly composed of cellulose. Cellulose is a complex
substance and provides structural strength to plants.
When a living plant cell loses water through osmosis there is shrinkage or
contraction of the contents of the cell away from the cell wall. This phenomenon
is known as plasmolysis.
Cell walls permit the cells of plants, fungi and bacteria to withstand very dilute
(hypotonic) external media without bursting. In such media the cells tend to take
take up water by osmosis. The cell swells, building up pressure against the cell
wall. The wall exerts an equal pressure against the swollen cell.
Because of their walls, such cells can withstand much greater changes in the
surrounding medium than animal cells.
CELL WALL
11. (a) Mount the peel of a Rhoeo leaf in water on a slide and examine cells under
the high power of a microscope. Note the small green granules, called
chloroplasts. They contain a green substance called chlorophyll. Put a strong
solution of sugar or salt on the mounted leaf on the slide. Wait for a minute and
observe under a microscope.
What do we see?
(b) Now place some Rhoeo leaves in boiling water for a few minutes. This kills
the cells. Then mount one leaf on a slide and observe it under a microscope. Put
a strong solution of sugar or salt on the mounted leaf on the slide. Wait for a
minute and observe it again.
What do we find? Did plasmolysis occur now?
Conclusion: Only living cells, and not dead cells, are able to absorb or lose water
by osmosis.
Activity: To observe the phenomenon of plasmolysis
13. Questions
1. How do substances like CO2 and water move in and out of the cell?
Discuss.
2. Why is the plasma membrane called a selectively permeable membrane?
3. What do you mean my osmosis and diffusion?
4. Describe the following terms:
a) Hypotonic medium
b) Hypertonic medium
c) Isotonic medium
5. Define the term plasmolysis.
6. What are the constituent molecules of the plasma membrane?
7. What is cell wall. Define its role in plant.
8. What is the main constituent element of cell wall?
15. BACTERIA CELL
(BACILLUS TYPE)
MESOSOME: an organelle of bacteria that appears as an invagination of the plasma membrane and functions
either in DNA replication and cell division or excretion of exoenzymes.
Nucleoid