The RE-AIM framework was developed to evaluate the public health impact of interventions beyond just efficacy. It consists of 5 dimensions: Reach, Efficacy, Adoption, Implementation, and Maintenance. These dimensions measure the individual and setting-level outcomes of an intervention to better understand its real-world impact and sustainability over time. While all dimensions are important, they may be weighted differently depending on the evaluation. The framework is used in planning, monitoring, and reporting the results of interventions and has applications outside of just public health evaluations.

1. RE-AIM
Reach
Efficacy
Advocate
Implement
Maintenance
Framework Use in Clinical Research

2. Theory vs. Model vs. Framework: Nilsen
• Theory: principles, statements to explain things of the world;
explanatory and descriptive
• Model: a narrowed theory; descriptive
• Framework: structure, overview, outline of descriptive
categories

3. Pre-RE-AIM
• Impact of interventions
• I = R * E
• Missing aspects public health impact
• Did not take setting into consideration

4. Nilsen, P 2015

5. RE-AIM
• Reach: Individual level measurement; participation out of
population
• Efficacy: Biological, behavioral outcomes, and QOL to measure
success
• Adoption: representation in the settings
• Implementation: individual (adherence) and setting (protocol
deviations)
• Maintenance: post study sustainability

6. RE-AIM1999 •- Public Health
- Evaluation
- All 5 are equally
important but may be
weighted differently
- Internal/External
validity
- Individual
interventions
Overtime
- Used in planning,
progress, report results
- Used outside of public
health
- Confusion over term
use
- Not all dimensions
used