Pre-formulation studies form an important phase in drug formulation or development. And you can’t afford to make an error in them. There comes CogniBrain to aid your pharmaceutical formulation and drug development in a trendy, fast, and flawless manner. Troubleshoot your pre-formulation and formulation errors now!

1. What
Is
Pharmaceutical
Formulation?

2. Pharmaceutical formulation
is the process of combining
different chemical substances
with the active drug to form
the final medicinal product

3. It is obtained after in-depth
study of physical, chemical,
and mechanical properties of
the drug substance

4. What is the objective of drug formulation?
To produce a final medicinal product
that is stable and acceptable to the
patient

5. Factors considered during
pharmaceutical formulations
• Physical, chemical, and mechanical properties
of drug substance
• Polymorphism, solubility, pH, and particle size
of drug
• Inactive ingredients or excipients to be added
• Effectiveness of the drug in phase I clinical
trials
• Results of drug stability studies

6. These factors are known
through preformulation
studies

7. Types of formulations
• Enteral formulations
• Parenteral formulations
• Topical formulations

8. Enteral Formulations
o Available as capsules or tablets
o Used for oral administration of the drug
o Can provide rapid effect or sustained release
from the digestive tract

9. Parenteral Formulations
Available in liquid or lyophilized form
Used for intravenous, intra-articular,
intramuscular, and subcutaneous administration.
Liquid form is preserved in ampoules, IV bags,
vials, and prefilled syringes in refrigerators
Lyophilized form is kept in dual chamber syringes,
cartridges, and vials in refrigerators

10. Topical Formulations
Available as creams, ointments, powders or
inhaling formulas
Used for skin application or nasal
administration

11. Effects of containers on formulations
After the drug is formulated, it is stored in
containers of plastic, glass, and metal
The effect of this storage in closed containers
is observed for extended period
Any unwanted reaction between the
formulation and container is noted

12. To know whether to formulate
a drug as enteral, parenteral or topical
formulation

13. You
need
a
formulation
scientist!

14. What does a formulation scientist do?
Helps you in pharmaceutical pre-formulation
studies
Analyzes the results of pre-formulation studies
Conducts pharmaceutical drug or formulation
development services
Evaluates the finished medicinal product

15. To Know more
Email ID: project@cognibrain.com
Phone: 044-49595223
Visit us: https://www.cognibrain.com
Connect with us: