This document discusses how to formulate research hypotheses. It states that hypotheses should be written before a study begins and not changed later. Hypotheses use null and alternative forms, and directional alternative forms are better. A good hypothesis includes the dependent and independent variables, their relationship, the population studied, and significance level. It provides an example hypothesis about different dressings and bleeding complications. Additional tips are that hypotheses must be testable, use present tense, contain a single prediction, and ideally be limited to six or fewer. Criteria for evaluating hypotheses include clarity, structure, variables, population, testability and significance level. A well-stated hypothesis predicts the relationship between dependent and independent variables for a population at a given significance