This document discusses the use of fluoridated elastic chains in orthodontic treatment to help prevent dental caries. It summarizes several studies that found fluoridated elastic chains initially release high levels of fluoride that decrease over time, but provide continuous low-level fluoride release. While fluoride chains showed greater force degradation than conventional chains, increasing the initial extension can compensate. A clinical study found patients using fluoridated chains had less enamel decalcification compared to a control group. Stretching fluoridated chains increases the amount of fluoride released by around 7%.
History
Natural Sources Of Fluoride
Physiology and metabolism of fluoride
Fluoride in Dentistry
Control of dental caries
Fluoride toxicity
Dental fluorosis
Fluorosis indices
Water defluoridation
Conclusion
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
History
Natural Sources Of Fluoride
Physiology and metabolism of fluoride
Fluoride in Dentistry
Control of dental caries
Fluoride toxicity
Dental fluorosis
Fluorosis indices
Water defluoridation
Conclusion
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
overview of flouride with detailed information on their pharmacological action, mechanism, uses and adverse effect for both medical and dental students.
Dental caries is the major dental disease affecting a large population. Cariostatic efficacy of the fluorides have increased the use of fluoride agents. This presentation will enlighten us about the use of fluorides in preventive dentistry.
Topical Fluorides- Professionally applied & Self appliedDrSusmita Shah
An overview of Topical Fluorides. Includes mechanism of action of topical application of fluorides- professionally and self applied. Recommendations of use of Fluorides in pediatric dentistry.
overview of flouride with detailed information on their pharmacological action, mechanism, uses and adverse effect for both medical and dental students.
Dental caries is the major dental disease affecting a large population. Cariostatic efficacy of the fluorides have increased the use of fluoride agents. This presentation will enlighten us about the use of fluorides in preventive dentistry.
Topical Fluorides- Professionally applied & Self appliedDrSusmita Shah
An overview of Topical Fluorides. Includes mechanism of action of topical application of fluorides- professionally and self applied. Recommendations of use of Fluorides in pediatric dentistry.
learning objectives
Introduction
History Of Water Fluoridation
How Does Fluoride Act In Dental Caries Prevention?
Goals Of F Administration
Fluoride Administration
Appropriate Levels Of Fluoride in Drinking Water
Methods of water fluoridation
--------------------------------------------------------------------
Efficacy Of topical fluorides
Range Of therapeutic fluoride concentrations used to prevent caries
Recommended doses
This presentation summarizes the caries formation process and fluoride mode of action
It further discusses the different types of fluoride available and their relative efficacies
13th publication - Dr Rahul VC Tiwari - Department of oral and Maxillofacial Surgery, SIBAR Institute of Dental Sciences, Takkellapadu,Guntur, Andhra Pradesh - 522509. IJCR JOURNALS
It is generally accepted that a low level of fluorine in mains water 0.4 to 1 mg -¢ L – 1 depending on the climate of the country concerned promotes the formation of tooth enamel and protects teeth from decay. On the other hand, too much fluorine will destroy this enamel and cause a range of endemic type disorders that are generally called “fluoroses- malformed teeth, staining of the enamel, decalcification, tendon mineralisation, digestive and nervous disorders, etc. These problems can appear in individuals for widely variable quantities of the product. Water must be discharged or treated as soon as it contains more than 1 to 1.5 mg -¢ L – 1 of F – . Some natural waters contain more than 10 mg -¢ L – 1 of fluorine. This concentration has to be reduced to approximately 1 mg -¢ L – 1 the acceptable concentration falling as the average annual temperature rises the European standard has set 1.5 mg -¢ L – 1. Many studies have been carried out to address the issue however little success has been reported up to date. Layered double hydroxides LDHs which readily undergo anion exchange reactions have been used as a suitable candidate for defluorination. Also there is regeneration of the material after removal of fluoride ions without releasing flouride ions back in to the water cycle. F elimination using a nanofiltration NF operation will solve problems for large scale pilot plants in the future.Many defluorination projects have significant effectiveness on the prevention of endemic fluorosis. The concentrations of water fluoride were below 1 mg L. Advanced on site methods, such as under sink reserve osmosis units, can remove fluoride but are too expensive for developing areas. Calcium carbonate as a cost effective sorbent for an onsite defluorination drinking water system. Batch and column experiments have been performed to characterize F removal properties. The present review discusses various techniques of defluorination of water. Dr. Atul Kumar Sharma | Dr. Harsukh Ram Chharang "Defluorination of Drinking Water" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-5 , August 2021, URL: https://www.ijtsrd.com/papers/ijtsrd46324.pdf Paper URL: https://www.ijtsrd.com/chemistry/other/46324/defluorination-of-drinking-water/dr-atul-kumar-sharma
Indian Dental Academy: will be one of the most relevant and exciting training center with best faculty and flexible training programs for dental professionals who wish to advance in their dental practice,Offers certified courses in Dental implants,Orthodontics,Endodontics,Cosmetic Dentistry, Prosthetic Dentistry, Periodontics and General Dentistry.
Topical fluoride is very important to decrease or arrest dental caries. Fluroides are topical and systemic. Fluorides prevents caries in children. There are various forms fluorides available in market . Fluridated toothpastes, mouthrinses, tablets.
selection of preformed arch wires during the alignment stage of preadjusted o...MaherFouda1
This slideshow helps clinicians in the orthodontic field to select the proper arch wire for their patients to achieve proper and efficient treatment and outcomes.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
Follow us on: Pinterest
Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
3. Increasing host
resistance is one
way to prevent
demineralization
and caries and
application of
fluoride is an
accepted means of
reduction of caries
incidence during
orthodontic
treatment
4. Incorporating fluoride
ions in
elastomerics as a
source of fluoride-
release is
suggested as one
way to convey
fluoride
continuously into
saliva if there is
regular elastomeric
change during
space closing
5. Role of fluoride in caries
prevention
2 major aspects of
fluoride action are:
1- inhibition of
demineralization at
the crystal surfaces
2- enhancement of
subsurface
mineralization
resulting in
arresment or reversal
of caries lesion
6. Mode of topical fluoride
delivery
a) Water fluoridation
b) Oral rinse
containing fluoride
c) Fluoride dentrifices
d) Fluoride tablets
e) Professionally
applied fluoride
preparations
8. 1- Fluoride containing etchant
Several studies
concluded that
addition of fluoride
to etchant had no
significant effect to
enamel caries
prevention or
deterioration on the
etching effect on
enamel
9. 2- Fluoride containing
cements
Polyalkenoate cements
were clinically
associated with less
demineralization than
zinc phosphate or
zinc polyacrylate
Sadowsky et al (1981)
demonstrated that
fluoride containing
cements have
preventive effect on
demineralization
10. 3- Fluoride-containing bonding
adhesives
These are glass
ionomer cements
and composite resin
An in vitro study (Valk
and Davidson,
1987) indicated that
glass ionomer
cement protected
an area of
approximately 1 mm
wide around the
orthodontic bracket
11. 4- Fluoride-releasing elastomeric
ties
An in vitro study by
Schemehom and
Farnham (1988)
showed that the
10% stannous
fluoride elastomeric
ties showed
greater
remineralization of
adjacent enamel
than the 1.4% ties
12. 5- Fluoride releasing elastic
chain
Upon stretching of
these chains, 7%
increase in fluoride
release is observed
13. Fluoride Release from
Orthodontic Elastic Chain
A study done by Joseph et al (1993) suggested
that the rate and amount of stannous fluoride
release from a fluoride-releasing power chain
was initially high (0.106 mg/hour between 6-24
hours) but dropped after 72 hours and
remained at low levels until the end of
experimental periods
14. Elastic properties of fluoride
chains
A study was
conducted to
investigate whether
or not fluoride affects
the elastic properties
in wet conditions
and dry conditions
by comparing
conventional non-
fluoride-releasing
elastic chain with
fluoride-releasing
elastic chain
15. This study revealed
that force
degradation was
more rapid in
fluoride releasing
chains than
conventional ones
The decay in wet
conditions was
greater than that of
dry conditions
16. The study suggests
that since fluoride
affects the force
degradation of the
chain, increasing the
percentage of
extension at the
commencement
might compensate
for the force loss rate
and still maintain
adequate activation
in closing spaces
17. Effectiveness of Fluoride
releasing chains
In a study on 49
patients (782 teeth)
who used fluoridated
elastic chains and
were compared with
a control group of 45
patients (740 teeth),
enamel
decalcification
incidence and
distribution were
recorded
18. In the control group,
decalcification
occurred in 73% of
patients and 26%
of all teeth while in
the group
undergoing the
experiment it
occurred in 63% of
patients and 16%
of all teeth
19. The effect of stretching on the
release of fluoride
Stretching increases the
concentration and
amount of fluoride
released
Stretched fluoridated
elastic chains release
approximately 32
gF.day/ml while the
unstretched ones
release 30 gF.day/ml.
This represents a 7%
increase in fluoride
release