Both the GammaKnife and CyberKnife are robotic radiosurgery machines that provide painless, non-surgical treatment for benign or malignant tumors. The GammaKnife was developed in 1968 and is used to treat tumors in the brain, while the CyberKnife, developed in 1994, can treat tumors anywhere in the body without immobilizing frames. Both procedures involve delivering high doses of radiation with minimal side effects and allow patients to resume daily activities shortly after treatment.
CyberKnife: Radiosurgery System Introductionduttaradio
Radiation source is mounted on a precisely controlled industrial robot.
- Image guidance system(continuous tracking system)
- Eliminates the need of gating techniques and restrictive head frames
CyberKnife: Radiosurgery System Introductionduttaradio
Radiation source is mounted on a precisely controlled industrial robot.
- Image guidance system(continuous tracking system)
- Eliminates the need of gating techniques and restrictive head frames
Wireless Indoor Localization with Dempster-Shafer Simple Support FunctionsVladimir Kulyukin
A mobile robot is localized in an indoor environment
using IEEE 802.11b wireless signals. Simple support
functions of the Dempster-Shafer theory are used to combine evidence
from multiple localization algorithms. Emperical results
are presented and discussed. Conclusions are drawn regarding
when the proposed sensor fusion methods may improve performance
and when they may not.
A summary of recent innovations in radiation oncology focussing on the priniciples of different techniques and their application. An overview of clinical results has also been given
A brain tumor is an abnormal growth of cells within the brain or the central spinal canal that can be cancerous or benign. Learn more about brain tumors and how Louisville CyberKnife's noninvasive treatment may work for you by calling (502) 217-8200.
The CyberKnife® Robotic Radiosurgery System is the world’s first and only robotic radiosurgery system designed to treat tumours anywhere in the body with sub-millimeter accuracy.
Discover the future of cancer care at Apollo Proton Cancer Centre. Leading the way in medical oncology with advanced treatments for a brighter tomorrow.
CyberKnife Center of Chicago presents the American Cancer Society Facts and Figures 2014 annual report outlining the estimated numbers of new cancer cases and deaths in 2014 as well as current cancer incidence, mortality, and survival statistics and information on cancer symptoms, risk factors, early detection and treatment.
CORPORATIVE PRESENTATION Nuclear Medicine World.pdfCaro42056
Presentacion corporativa de Nuclear Medicine World, empresa líder en latinoamerica en medicina nuclear.
Ofrece soluciones personalizadas y consultorias en Medicina Nuclear, PET CT, SPECT, Terapias, Radiofarmacia, etc.
A brain tumor is an abnormal growth of cells within the brain or the central spinal canal that can be cancerous or benign. Learn more about brain tumors and how CyberKnife Center of Chicago's noninvasive treatment may work for you
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
2. Is knife less surgery the way to go?
Thanks to modern technology, patients can now have some surgeries without
being cut open! There are two types of surgery that can be done without going
under the knife: Gammaknife and/or Cyberknife. In order to better understand
these, lets take a look at the following topics/ questions:
● What is Gammaknife/Cyberknife?
● Understanding GammaKnife Surgery!
● Who came up with these procedures? (The History)
● What is the difference between GammaKnife and CyberKnife surgery?
● What can be treated with these procedures?
● Are there any side effects?
● What local hospitals perform these surgeries?
● Are there any new developments or technological advances regarding the
Gammaknife and Cyberknife.
Simren Smith
Stephanie Arthur
3. Both the GammaKnife and CyberKnife are robotic radiosurgery
machines that provide painless, non-surgical treatment for benign
or malignant tumors.
What is GammaKnife/CyberKnife?
Cyberknife Gammaknife
Stephanie Arthur
4. Who came up with these procedures?
The CyberKnife was developed by
John Adler, a doctor at Stanford. In
1994, the first patient was treated at
Stanford using the CyberKnife. It was
approved by the FDA in 2001. Over
5,500 patients at Stanford have been
treated using the Cyberknife.
The GammaKnife was developed by
Swedish neurosurgeon, Dr. Lars
Leksell and colleague, Borje Larsson
in 1968. It was introduced to the U.S.
in 1987. More than 300,000 patients
have been treated with the
GammaKnife.
Stephanie Arthur
The first GammaKnife 1968
5. What is the difference between the
Gammaknife and Cyberknife?
The GammaKnife is used to treat brain tumors. The
procedure begins with the patient receiving anesthesia and
a frame is attached to the head to hold it in place. The
patient lays on their back and is moved head first into the
machine, where 201 beams of radiation target the
diseased tissue, without damaging the surrounding tissue.
The CyberKnife is made up of a radiation delivery device
(Linac) attached to a robotic arm. This allows the
Cyberknife to be able to treat tumors anywhere in the body.
There is no need for a patient to be still or head frames to
hold them in place because the Cyberknife automatically
adjusts to the movement of the patient or tumor. The
Cyberknife is pain-free, no anesthesia is required.
Stephanie Arthur
8. What conditions can be treated by
GammaKnife surgery?
● Malignant tumors such as metastases (cancer that has spread to the brain)
and malignant gliomas
● Benign tumors such as meningiomas, acoustic neuromas (vestibular
schwannomas), pituitary tumors and low grade glioma and skull-based
tumors
● Vascular malformations such as arteriovenous malformations (AVMs) and
cavernous angiomas (cavernous malformations)
● Parkinson’s disease
● Lesions causing epilepsy
9. What conditions can be treated by
CyberKnife surgery?
● Many types of tumors or lesions can be treated. In addition, other
conditions throughout the body can be treated with CyberKnife. Among
these are:
● Cancers in the brain, liver, lung, pancreas, prostate, kidney, head and
neck, spine and other soft-tissue sites
● Certain benign tumors
● Malformations of blood vessels within the brain or
spine
● Symptomatic functional disorders of the
neurological system
10. Are there any side effects?
CyberKnife patients rarely experience side
effects from treatment and can immediately
resume daily activities.
GammaKnife patients may have a headache
or swelling from the head frame after the
procedure, but many patients report no
problems and can resume daily activities within
a day or so.
Stephanie Arthur
11. Where can one have GammaKnife
surgery in Ohio?
Gamma Knife Center
Kettering Medical Center
3535 Southern Blvd.
Kettering, OH 45429
(937) 395-8488 or (800) 834-9815.
The James Cancer Hospital and Solove Research
Institute
300 West 10th Avenue, Suite 519
Columbus, OH 43210
(614) 293-5066 or (800) 293-5066
Ohio Ear Institute, LLC
387 County Line Road West
Suite #115
Westerville, OH 43082
(616) 891-9190
12. Where can one have CyberKnife
surgery in Ohio?
Columbus CyberKnife
495 Cooper Rd., Suite 125
Westerville, OH 43081
614.898.8300
First Dayton CyberKnife
2632 Woodman Center Court
Dayton, OH 45420
937.293.2273
Alternative Phone: 855.DAY.TON1
Fax: 937.293.6573
University Hospitals - Seidman Cancer Center
11100 Euclid Avenue
Cleveland, OH 44106
Phone: +1.800.641.2422
13. Gamma Knife Society- New
Developments
The Gamma Knife Society is a society of
individuals who get together to discuss new
developments of the GammaKnife.
Gamma Knife Society Meeting
14. About The Society:
The Leksell Gamma Knife® Society was founded in 1989 as a forum for Gamma Knife clinicians, physicists and researchers
to exchange information, experiences and clinical techniques, as well as clinical data on the use of Leksell Gamma Knife.
Mission statement:
The mission of the Leksell Gamma Knife Society is to further define and expand the role of Gamma Knife Surgery in the
treatment of intracranial disorders. The development of best practices in order to improve patient outcomes is an important
objective of the Society. Membership is open to practitioners at all Gamma Knife sites.
Objectives:
● Improve results achieved in the field of radiosurgery by promoting support of basic and clinical research, with a focus
on expanding the role of Leksell Gamma Knife
● Increase the visibility and acceptance of Leksell Gamma Knife technique in the worldwide medical community and
among healthcare providers and patients
● Maintain leadership in the field of radiosurgery by continued commitment to the highest standards of research and
technical achievement
● Stimulate multi-center trials and cross-site collaboration
15. How many different machines are
there?
The GammaKnife currently has five different versions; U, B, C,
4C, and Perfexion.
The M6 is the newest CyberKnife series, with three models, FIM,
FM, and FI. There are also the Cyberknife VSI and G4 versions.
Stephanie Arthur
16. Summary
The GammaKnife and CyberKnife are Robotic radiosurgery
devices that deliver high doses of radiation to treat tumors and
abnormalities of blood vessels and arteries in the brain and
spinal cord. Both procedures involve no cutting, are painless,
and have minimal side effects if any at all. The CyberKnife was
developed at Stanford and it’s flexible arm allows it to adjust to
movement from patient or tumor, and can treat anywhere in the
body. The GammaKnife was invented by a Swedish
neurosurgeon, and introduced to the U.S. in 1987. The patient
lays down and their head is attached to a head frame to hold it
in place then they are moved into the machine, the
GammaKnife is used to treat tumors and abnormalities in the
brain and spinal cord.
Stephanie Arthur
18. Picture Websites:
“News & Events." Oklahoma CyberKnife. N.p., n.d. Web. 06 Aug. 2013. http://www.oklahomack.com/our-
center/news-events/
“Gammaknife Then and Now: 3,000 Patients and Counting.” | Columbia Neurosurgery."Columbia Neurosurgery. N.
p., n.d. Web. 06 Aug. 2013
http://www.columbianeurosurgery.org/2012/02/gamma-knife-then-and-now-3000-patients-and-counting/
“How the Gammaknife Works-Gamma knife surgery.” Tufts Medical Center. N.p., N.d. Web. 06 Aug. 2013
http://www.tuftsmedicalcenter.
org/OurServices/SpecialServicesandCenters/BostonGammaKnifeCenter/HowGammaKnifeWorksGammaKnifeHist
ory
“Premier Cancer Centers Dallas.” Merchant Circle. N.p., 2013. Web. 06 Aug. 2013
http://www.merchantcircle.com/business/Premier.Cancer.Centers.2149547734/picture/view/4487567
“A Radical Treatment for Obsessive Compulsive Disorder Patients.” The Gaurdian. Lucy Atkins. 14 Dec. 2009.
Web. 06 Aug. 2013 http://www.theguardian.com/lifeandstyle/2009/dec/15/obsessive-complusive-disorder-gamma-
knife
Stephanie Arthur
19. Content Websites:
"What Is the CyberKnife® System?" CyberKnife::What Is CyberKnife? N.p., n.d. Web. 06 Aug. 2013. http://www.
cyberknife.com/cyberknife-overview/what-cyberknife.aspx?linkidentifier=id
Cyberknife Robotic Radiosurgery System N.p., 2012. Web 06 Aug. 2013. http://www.cyberknife.
com/uploadedFiles/CyberKnife_Overview/500929.A_CyberKnife_Patient_Brochure_FINAL.pdf
"CyberKnife M6 Series." Accuray. N.p., n.d. Web. 06 Aug. 2013. http://www.accuray.com/solutions/treatment-
delivery/cyberknife-treatment-delivery/m6-series
“Stanford Cyberknife Stereotactic Radiosurgery.” Stanford Hospital and Clinics. N.p., 2013. Web 06 Aug. 2013.
http://stanfordhospital.org/clinicsmedServices/COE/cyberknife/
“Who We Are-Fact Sheet. Tufts Medical Center. N.p., 2013. Web 06 Aug. 2013 http://www.tuftsmedicalcenter.
org/OurServices/SpecialServicesandCenters/BostonGammaKnifeCenter/WhoWeAreFactSheet
“Overview: History and Technical.”-- School of Medicine at the University of Virginia N.p., 2013. Web. 06 Aug.
2013http://www.medicine.virginia.edu/clinical/departments/neurosurgery/gammaknife/overview-page
“Vascular Malformations.” Cavernous Malformations. N.p., N.d. Web 06 Aug. 2013.
http://www.pennstatehershey.org/web/stroke/patientcare/services/cavernous
I
Stephanie Arthur