This document discusses Prune Belly Syndrome, a rare genetic birth defect affecting 1 in 40,000 births, mostly males. It consists of a triad of symptoms: 1) gross ureteric dilatation, 2) anterior abdominal wall underdevelopment resulting in a "prune belly" appearance, and 3) bilateral undescended testes. Ultrasound findings that can indicate Prune Belly Syndrome include a dilated bladder/ureters, distended abdomen, and lack of amniotic fluid. The syndrome results in an underdeveloped or absent abdominal muscle wall, urinary tract abnormalities, and undescended testes in males.

1.  Dr Arun Gupta
Director imaging
 Dr Rakhee gupta
Dr Vinayak Mittal
 Dr Kiran
Dr Ritesh Mahajan
Abdominal Muscle Deficiency Syndrome,
Congenital Absence of the Abdominal
Muscles, Eagle-Barrett Syndrome, Obrinsky
Syndrome,Fröhlich Syndrome, or rarely,
Triad Syndrome.
FETALANOMALYSERIES
ADVANCED USG LOUNGE

2.  The prune belly syndrome is a rare anomaly
comprising a specific constellation of features. It
consists of three major findings :
1. Gross ureteric dilatation
2. Anterior abdominal wall underdevelopment
(resulting in the "prune belly" appearance)
3. Bilateral undescended testes .
There is often an association with other respiratory,
gastrointestinal, musculoskeletal, and
cardiovascular anomalies.

3. FETAL ABDOMEN
FETAL
SPINE
An ultrasound examination
that reveals a dilated
bladder and/or fetal
ureters, a distended fetal
abdomen, and
oligohydramnios, either
alone or in combination,
should alert a physician to
the possibility of Prune-
Belly syndrome.

4. GORSS MASS EFFECT
LEAD TO POOR
DISCRETE
VISUALIZATION OF
THE REST OF THE
ABDOMINAL
VISCERA .
FETAL HEAD
FETAL ABDOMEN
GROSSS DISTENSION
SEQUAELTO FETAL
MEGACYSTIS
DORSUM OF
FETALTORSO
RENDERED IMAGE

5. AC IS
CORROBORTAIVE
WITH POG OF 20WKS
REST OF THE FETAL
BIOMETRY IS
CORROBORATIVE
WITH 14WKS.
THIS IS SEQUAEL TO
GROSS ABDOMEN
DISTENSION OWING
TO MEGACYSTIS

6. FETAL SPINE
NORMALCORONALVIEW
OLIGOHYDRAMNIOS

7. GROSS DISTENSION OF
THE
FETAL ABDOMEN LEADING
TO MASS EFFECT ON THE
THORACIC CAVITY
( VOLUME LOSS)

8. A partial or complete lack of abdominal
muscles .There may be wrinkly folds of skin
covering the abdomen.
Undescended testis in males
Urinary tract abnormality such as unusually
large ureters, distended bladder,
accumulation and backflow of urine from the
bladder to the ureters and the kidneys
Frequent urinary tract infections due to the
inability to properly expel urine.
Later in life, a common symptom is post-
ejaculatory discomfort. Most likely a bladder
spasm, it lasts about two hours.

9. Prune belly syndrome is
a rare, genetic birth
defect affecting about 1
in 40,000 births.About
97% of those affected
are male. Prune belly
syndrome is a
,congenital disorder of
the urinary system
characterized by a triad
of symptoms.
PRUNE BELLY SYNDROME ………..

10. DIFFERENTIAL DIAGNOSIS OF
PRUNE-BELLY SYNDROME.
 Megacystis-microcolon-
intestinal hypoperistalsis
syndrome
 Posterior urethral valve
syndrome
 Ureteropelvic junction
obstruction
 Bladder exstrophy
 Urachal cyst
 Enteric duplication cyst
Ascites
SONOGRAPHIC FINDINGS OF
PRUNE-BELLY SYNDROME.
 Persistent megacystis
 Persistent dilatation of the
proximal urethra
 Thickening of the bladder
wall in the setting of
oligohydramnios
D/D AND SONOGRPAHIC FINDINGS

11. DIAGNOSTIC
ULTRASOUND
FOURTH EDITION
Carol M. Rumack, MD, FACR
J.William Charboneau, MD,
FACR
Deborah Levine, MD, FACR