Sudden Cardiac Arrest, is the sudden, unexpected loss of heart function, breathing and unconsciousness. The Victim may or may not have diagnosed heart disease. It occurs within minutes after symptoms appear. Over 350,000 people a year die of from Sudden Cardiac Arrest, which leads the United States for deaths each year. It’s a medical emergency that, if not treated immediately, is fatal. With fast, appropriate medical care, survival is possible.
Sudden Cardiac Arrest, is the sudden, unexpected loss of heart function, breathing and unconsciousness. The Victim may or may not have diagnosed heart disease. It occurs within minutes after symptoms appear. Over 350,000 people a year die of from Sudden Cardiac Arrest, which leads the United States for deaths each year. It’s a medical emergency that, if not treated immediately, is fatal. With fast, appropriate medical care, survival is possible.
Heart Diseases in Men and Women are the number 1 cause of death in United States. 1 out of 4 deaths in U.S are caused by Heart Diseases. But this can be controlled or avoided if proper medical attention were given at the right time. In some cases, various symptoms are seen prior to serious heart issues, which could be treated or controlled by getting medical attention from a doctor.
Acute limb ischaemia
Joel Arudchelvam
MBBS (COL), MD (SUR). MRCS (ENG)
Consultant Vascular and Transplant Surgeon
The National Hospital of Sri Lanka , Colombo
Definition
Causes
Differentiating thrombosis and embolism
Heart Diseases in Men and Women are the number 1 cause of death in United States. 1 out of 4 deaths in U.S are caused by Heart Diseases. But this can be controlled or avoided if proper medical attention were given at the right time. In some cases, various symptoms are seen prior to serious heart issues, which could be treated or controlled by getting medical attention from a doctor.
Acute limb ischaemia
Joel Arudchelvam
MBBS (COL), MD (SUR). MRCS (ENG)
Consultant Vascular and Transplant Surgeon
The National Hospital of Sri Lanka , Colombo
Definition
Causes
Differentiating thrombosis and embolism
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Trauma,mechanism,classification, pathophysiology, sign and symptoms, thorough...Shivangi sharma
Trauma occurs when both internal and external resources are inadequate to cope with external threat.A traumatic event is one in which a person experiences (witnesses or is confronted with):
Actual or threatened death
Serious injury
Threat to the physical integrity of self or another
So you want to be a doctor? It's a long, hard road but filled with many rewards. How I became a doctor, surgeon, ED physician... and why it's so rewarding
Presentation by John Peterson at RMH Field Care Audit on 1/18/12. videos are posted on youtube.com/4docmontey
http://youtu.be/ahCxJ5vEcF0
http://youtu.be/Av0IJ-THnIE
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
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ASA GUIDELINE
NYSORA Guideline
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Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
10. Blunt Force Trauma
Injury due to pressure force
Hit by moving object
Hit or fall against solid
object
Object exerts pressure
Tears and hematomas to
solid organs
14. Blunt Force Trauma
Injury because of sudden
halt
MVC most common
Acceleration factor
greatest in air travel
Stretching & linear shearing
of fixed or free organs
72. Blunt Force Trauma
C spine precautions placed when:
– Any neck discomfort or numbness in
extremities
– Not fully alert or AMS
– Other painful injuries
73. Blunt Force Trauma
C spine precautions placed when:
– Any neck discomfort or numbness in
extremities
– Not fully alert or AMS
– Other painful injuries
74. Blunt Force Trauma
Rigid collars, such as the Philadelphia
and the extrication collars, reduce
flexion and extension to about 30%
normal and rotation and lateral
movement to about 50%.
75. Blunt Force Trauma
best immobilization method
– secure patient to a hard board
– place sandbags at either side of head
– rigid collar around the neck
– decreases movement to about 5% of
normal.
76. Blunt Force Trauma
Thoracic
Spine
12 vertebrae
Attached to
rib cage
Ligaments
Anterior
Posterior
83. Head and Spine Injuries
Look for motor or
sensory deficits
Deficit will point to
location of injury
Remember dual
innervation of
cervical cape
Log roll & keep spine
in neutral position
91. Blunt Force Trauma
Rib Fractures
9 - 11 watch for intra-abdominal
injuries
Flail Chest
Three or more consecutive ribs
Broken in 2 or more places
Same side of chest
Paradoxical Chest Movement
92. Blunt Force Trauma
Lung contusions
More common in children
Serious cause of morbidity
Elderly
COPD
121. Blunt Force Trauma
Cardiac Injury
9 - 34% of thoracic injuries
Right atrium most susceptible
to injury
Will lead to EKG changes and
Troponin elevations
Contusio cordis vs commotio
cordis
122. Blunt Force
Trauma
Thoracic Aorta
Disruption
2nd leading cause
of death
93% at desc.
Aorta
Widened
mediastinum most
common finding
85%
123. Blunt Force
Trauma
Thoracic Aorta
Disruption
2nd leading cause
of death
93% at desc.
Aorta
Widened
mediastinum most
common finding
85%
124. Blunt Force
Trauma
Thoracic Aorta
Disruption
2nd leading cause
of death
93% at desc.
Aorta
Widened
mediastinum most
common finding
85%
129. Blunt Force Trauma
Diaphragmatic
injury
Strong
compressive
forces
Intrusion by
abdominal
viscera
Injury mostly
occurs on right
Bowel sounds
in the chest
134. Blunt Force Trauma
Most common type
50 – 70%
Liver & spleen
most commonly
injured
may not manifest
during initial
assessment &
treatment period
1.5L before
distention
appears
135. Blunt Force Trauma
Compression injuries
Liver lacerations
and hematomas
Splenic lacerations
and sequestration
Deceleration injuries
Kidney
Bowel injuries
Vascular injuries
136. Blunt Force Trauma
Hollow organ
injuries
Usually
secondary to
seatbelt
Compressive
forces increase
pressure
Deceleration
disrupts blood
supply from
mesenteric vessels
140. Blunt Force Trauma
Injured from trauma to:
Eighth through twelfth ribs on
right side of body
Upper central part of abdomen
Tear at falciform or direct
injury
Blood and bile will leak into
abdominal cavity
Shock
Peritoneal irritation
142. Blunt Force Trauma
Kidney
Firmly held in the
retroperitoneum
Severe
compression or
rib fractures
Deceleration
leads to shearing
of arteries
Spillage of blood
and urine into
retroperitoneum
143. Blunt Force Trauma
Pelvic Organ
Injuries
Most commonly
associated with
pelvic fractures
Urinary rupture
if compressive
force on full
bladder
154. Blunt Force Trauma
Bleeding
Bruising
Fracture
Laceration
Compartment Syndrome
155. Blunt Force Trauma
Not an acute
occurrence
Symptoms:
Pain out of
proportion/passive
motion
Parasthesias/
Paralysis
Pallor
Pulselessness
Poiklothermia
156. Blunt Force Trauma
Compartment Pressures
Normal about zero; usually less than 10 mm Hg
Capillary blood flow compromised at >20 mm Hg
Muscles/nerves at risk for ischemic necrosis
>30 to 40 mm Hg.
Nerve is most sensitive, followed by muscle
tissue.
157. Blunt Force Trauma
Traumatic Asphyxia Syndrome
Constrictive force to chest wall
Can occur within two minutes
Mechanism of injury - profound
venous hypertension
Cerebral hypoperfusion
158. Blunt Force Trauma
Vital signs
Tachycardia
Tachypnea
Signs of shock
Hypotension
Diaphoresis
Slow cap refill
Mental Status
Neurodeficits
Young will handle better than old