Physical exercise, particularly weight training, causes changes to the muscular system. Key changes include muscle hypertrophy, or an increase in muscle size and thickness. Chronic hypertrophy occurs with long-term weight training and causes an increase in total muscle protein and fiber size. Aerobic changes from endurance training include increases in myoglobin, mitochondria, and muscle enzyme levels, improving endurance. Anaerobic changes like increased ATP-PC and glycolytic capacity from sprint or weight training improve strength. Overall, weight training can reduce body fat and increase muscle mass without significantly changing total body weight.