This document provides information about typhoid fever including: - It is caused by the bacterium Salmonella Typhi and results in a systemic infection. - Globally there are an estimated 21 million cases annually. India reports over 1.5 million cases annually making it endemic. - It discusses epidemiological determinants like host factors, environmental factors, incubation period, and modes of transmission. - Clinical features include continuous fever for 3-4 weeks with relative bradycardia and involvement of intestinal lymphoid tissues. - Laboratory diagnosis and tests like blood and stool cultures and the Widal test are discussed. - Control methods focus on controlling reservoirs, cases, carriers and improving sanitation and immun