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CAMPYLOBACTERIOSIS
-Campylobacter jejuni
-ANUSHA B
MICROBIOLOGIST
ZOONOTIC DISEASE:
• Zoonosis is another name for a zoonotic disease.
• It is a type of disease that passes from an animal or insect to a
human.
• Zoonotic diseases ranges from minor illness to major life changing illness.
• They are transmitted through various ways:
• Through air
• By eating contaminated foods such as meat.
• Through close contact with infected animal.
• Through insect bites like mosquitos or ticks.
OTHER SPECIES
• C.jejuni- DIARRHEA IN HUMANS.
• C. lari – FOUND IN SEAGULLS, CAUSES MILD RECURRENT DIARRHEA IN
CHILDREN
• C.upsaliensis – CAUSES DIARRHEA OR BACTEREMIA
• C.hyointestinalis- CAUSES OCCASIONAL BACTEREMIA IN
IMMUNOCOMPROMISED INDIVIDUALS.
THE ORGANISM -
Campylobacter jejuni
• CAMPLYLOBACTERIOSIS AFFECTS INTESINAL TRACT AND CAUSES DIARRHOEA.
• Campylobacter COMMONLY MEANS CURVED ROD IN GREEK.
• Campylobacter Spp IS COMMONLY ASSOCIATED WITH POULTRY.
• C.jejuni IS A HELICAL SHAPED, GRAM NEGATIVE ORGANISIM.
• MOTILE ORGANISIM WITH SINGLE FLAGELLA.
• DARTING MOTILITY.
• OPT. TEMPERATURE IS 37.
• SELECTIVE MEDIA: CHARCOAL BASED SELECTIVE MEDIUM.
• SKIRROW’S MEDIUM.
• CATALASE- POSITIVE
• OXIDASE- POSITIVE
HOW IS IT SPREAD?
• THE BACTERIA IS COMMONLY FOUND IN GUT OF WARM BLOODED
ANIMALS AND BIRDS.
• INFECTS PEOPLE WHO DRINK UNPASTERURIZED MILK OR
COMNTAMINATED WATER OR EATING OF UNCOOKED MEATS.
• EVEN BE TRANSMITTED FROM IMPROPER HANDLING OF
SLAUGHTERING PRACTICES.
• UNDERECOOKED POULTRY IS THE MAJOR CONTRIBUTOR TO THIS
DISEASE.
• UNCHLORINATED WATER MAY SOMETIMES BE AS A SOURCE.
PATHOGENESIS:
PATHOGENESIS:
• INFECTION CAUSING- BACTERIA PENETRATES GI MUCOUS.
• ADHERES TO GUT ENTEROCYTES.
• INDUCE DIARRHOEA.
• TOXINS INVOLVED: ENTEROTOXIN AND CYTOTOXIN.
• COLONIZES: LARGE AND SMALL INTESTINE.
• INFECTIVE DOSE: 800 ORGANISMS.
• SYMPTOMS:
SEVERE DIARRHOEA WITH BLOOD TRACES,
FEVER
NAUSEA
ABDOMINAL PAIN
HEAD ACHE
LONG TERM DISORDERS- REACTIVE ARTHRITIS
TREATMENT:
• MOSTLY PEOPLE RECOVER WITHOUT ANY TREATMENT.
• PEOPLE WITH DIARRHEA SHOUKD DRINK PLENTY OF FLUIDS.
• SOMETIMES ANTIBIOTICS CAN BE USED TO REDUCE THE SYMPTOM
DURATION OR FOR THE ELIMINATION OF CARRIER STATE.
PREVENTION:
• GOOD HYGENIC SLAUGHTERING PRACTICES.
• HYGENIC FOOD HANDLING.
• BACTERICIDAL TREATMENT- HEATING OR PASTEURIZATION OR ANY
CHEMICAL TREATMENT.
• COOK FOOD THROUGHLY.
• PREVENT CROSS CONTAMINATION.
REFRENCES:
• Campylobacteriosis – Epidemiology (virginia.gov)
• Campylobacter (who.int)
• Campylobacter jejuni – Wikipedia
• Zoonosis: Definition, Types, and Diseases List (healthline.com)

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C.JEJUNI.pptx, ZOONOTIC DISEASES, MEDICAL MICROBIOLOGY

  • 2.
  • 3. ZOONOTIC DISEASE: • Zoonosis is another name for a zoonotic disease. • It is a type of disease that passes from an animal or insect to a human. • Zoonotic diseases ranges from minor illness to major life changing illness. • They are transmitted through various ways: • Through air • By eating contaminated foods such as meat. • Through close contact with infected animal. • Through insect bites like mosquitos or ticks.
  • 4. OTHER SPECIES • C.jejuni- DIARRHEA IN HUMANS. • C. lari – FOUND IN SEAGULLS, CAUSES MILD RECURRENT DIARRHEA IN CHILDREN • C.upsaliensis – CAUSES DIARRHEA OR BACTEREMIA • C.hyointestinalis- CAUSES OCCASIONAL BACTEREMIA IN IMMUNOCOMPROMISED INDIVIDUALS.
  • 5. THE ORGANISM - Campylobacter jejuni • CAMPLYLOBACTERIOSIS AFFECTS INTESINAL TRACT AND CAUSES DIARRHOEA. • Campylobacter COMMONLY MEANS CURVED ROD IN GREEK. • Campylobacter Spp IS COMMONLY ASSOCIATED WITH POULTRY. • C.jejuni IS A HELICAL SHAPED, GRAM NEGATIVE ORGANISIM. • MOTILE ORGANISIM WITH SINGLE FLAGELLA. • DARTING MOTILITY. • OPT. TEMPERATURE IS 37. • SELECTIVE MEDIA: CHARCOAL BASED SELECTIVE MEDIUM. • SKIRROW’S MEDIUM. • CATALASE- POSITIVE • OXIDASE- POSITIVE
  • 6. HOW IS IT SPREAD? • THE BACTERIA IS COMMONLY FOUND IN GUT OF WARM BLOODED ANIMALS AND BIRDS. • INFECTS PEOPLE WHO DRINK UNPASTERURIZED MILK OR COMNTAMINATED WATER OR EATING OF UNCOOKED MEATS. • EVEN BE TRANSMITTED FROM IMPROPER HANDLING OF SLAUGHTERING PRACTICES. • UNDERECOOKED POULTRY IS THE MAJOR CONTRIBUTOR TO THIS DISEASE. • UNCHLORINATED WATER MAY SOMETIMES BE AS A SOURCE.
  • 8. PATHOGENESIS: • INFECTION CAUSING- BACTERIA PENETRATES GI MUCOUS. • ADHERES TO GUT ENTEROCYTES. • INDUCE DIARRHOEA. • TOXINS INVOLVED: ENTEROTOXIN AND CYTOTOXIN. • COLONIZES: LARGE AND SMALL INTESTINE. • INFECTIVE DOSE: 800 ORGANISMS. • SYMPTOMS: SEVERE DIARRHOEA WITH BLOOD TRACES, FEVER NAUSEA ABDOMINAL PAIN HEAD ACHE LONG TERM DISORDERS- REACTIVE ARTHRITIS
  • 9. TREATMENT: • MOSTLY PEOPLE RECOVER WITHOUT ANY TREATMENT. • PEOPLE WITH DIARRHEA SHOUKD DRINK PLENTY OF FLUIDS. • SOMETIMES ANTIBIOTICS CAN BE USED TO REDUCE THE SYMPTOM DURATION OR FOR THE ELIMINATION OF CARRIER STATE.
  • 10. PREVENTION: • GOOD HYGENIC SLAUGHTERING PRACTICES. • HYGENIC FOOD HANDLING. • BACTERICIDAL TREATMENT- HEATING OR PASTEURIZATION OR ANY CHEMICAL TREATMENT. • COOK FOOD THROUGHLY. • PREVENT CROSS CONTAMINATION.
  • 11. REFRENCES: • Campylobacteriosis – Epidemiology (virginia.gov) • Campylobacter (who.int) • Campylobacter jejuni – Wikipedia • Zoonosis: Definition, Types, and Diseases List (healthline.com)