This newsletter from Apollo Bariatric Institutes provides information on obesity and weight loss efforts in India.
1) Chennai has the highest rates of obesity and obesity-related diseases among 11 major cities surveyed in India.
2) Support groups are important for weight loss maintenance, and Apollo has started a quarterly "Enlight" support group.
3) Bariatric surgery techniques like gastric bypass and sleeve gastrectomy can help patients lose over half their excess weight and resolve health conditions like diabetes when other methods have failed.
David Wiss MS RDN walks you through research on childhood adversity and the various ways that trauma can become embedded into physiology and impact health, such as eating behavior.
In this first lecture of 2013 at Cady Wellness Institute, Dr. Cady presented the facts and strategies in front of a live audience for rebroadcast on WNIN - our local public television station. These are the EXACT SLIDES used in the presentation. We would like to thank all of those in the live audience who attended. For questions or comments, please feel free to contact us at front desk@cadywellness.com or call the Institute at ()812) 429 - 0772.
"Nutrition Interventions Amidst an Opioid Crisis: The Emerging Role of the RD...Nutrition in Recovery
This presentation was given at the Food and Nutrition Conference and Expo (FNCE) on Sunday October 21, 2018 in Chicago. Here David Wiss MS RDN describes the impact of opioids on nutritional status and gastrointestinal health, identifies common disordered and dysfunctional eating patterns common to opioid-addicted populations, and describes nutrition therapy protocols for specific substances including opioids and for poly-substance abuse.
David Wiss MS RDN walks you through research on childhood adversity and the various ways that trauma can become embedded into physiology and impact health, such as eating behavior.
In this first lecture of 2013 at Cady Wellness Institute, Dr. Cady presented the facts and strategies in front of a live audience for rebroadcast on WNIN - our local public television station. These are the EXACT SLIDES used in the presentation. We would like to thank all of those in the live audience who attended. For questions or comments, please feel free to contact us at front desk@cadywellness.com or call the Institute at ()812) 429 - 0772.
"Nutrition Interventions Amidst an Opioid Crisis: The Emerging Role of the RD...Nutrition in Recovery
This presentation was given at the Food and Nutrition Conference and Expo (FNCE) on Sunday October 21, 2018 in Chicago. Here David Wiss MS RDN describes the impact of opioids on nutritional status and gastrointestinal health, identifies common disordered and dysfunctional eating patterns common to opioid-addicted populations, and describes nutrition therapy protocols for specific substances including opioids and for poly-substance abuse.
Body Image Eating Disorders Males - July 7 2009 Newfoundland, CanadaPaul Gallant
2009, Males and body image article published by Eating Disorders Foundation of Newfoundland & Labrador, Canada
About author www.linkedin.com/in/paulwgallant
Good things in life: Can coffee help in diabetes prevention?Coffee_Health
Drinking three to four cups of coffee per day may help to prevent type 2 diabetes according to research highlighted in a session report published by the Institute for Scientific Information on Coffee (ISIC), a not-for-profit organisation devoted to the study and disclosure of science related to coffee and health.
Recent scientific evidence has consistently linked regular, moderate coffee consumption with a possible reduced risk of developing type 2 diabetes. An update of this research and key findings presented during a session at the 2012 World Congress on Prevention of Diabetes and Its Complications (WCPD) is summarised in the report.
The report outlines the epidemiological evidence linking coffee consumption to diabetes prevention, highlighting research that shows three to four cups of coffee per day is associated with an approximate 25 per cent lower risk of developing type 2 diabetes, compared to consuming none or less than two cups per day . Another study also found an inverse dose dependent response effect with each additional cup of coffee reducing the relative risk by 7-8 per cent.
More than 11 million men and women in the United States struggle with an eating disorder. To raise awareness and understanding of these devastating diseases, Eating Recovery Center, a behavioral hospital focused on comprehensive treatment and sustainable recovery for eating disorders, has developed this Blogger’s Guide to Eating Disorders. This guide offers information and resources to support your stories about America’s deadliest mental illness.
For downloadable eating disorder resources, please visit http://bit.ly/8ZbVAO.
Long term spinal cord injury (SCI) and diabetes? Some research suggests the two go hand in hand with as
many as 20 percent of spinal cord injured people having adult-onset diabetes. If you have an SCI, what should
you know about diabetes?
Body Image Eating Disorders Males - July 7 2009 Newfoundland, CanadaPaul Gallant
2009, Males and body image article published by Eating Disorders Foundation of Newfoundland & Labrador, Canada
About author www.linkedin.com/in/paulwgallant
Good things in life: Can coffee help in diabetes prevention?Coffee_Health
Drinking three to four cups of coffee per day may help to prevent type 2 diabetes according to research highlighted in a session report published by the Institute for Scientific Information on Coffee (ISIC), a not-for-profit organisation devoted to the study and disclosure of science related to coffee and health.
Recent scientific evidence has consistently linked regular, moderate coffee consumption with a possible reduced risk of developing type 2 diabetes. An update of this research and key findings presented during a session at the 2012 World Congress on Prevention of Diabetes and Its Complications (WCPD) is summarised in the report.
The report outlines the epidemiological evidence linking coffee consumption to diabetes prevention, highlighting research that shows three to four cups of coffee per day is associated with an approximate 25 per cent lower risk of developing type 2 diabetes, compared to consuming none or less than two cups per day . Another study also found an inverse dose dependent response effect with each additional cup of coffee reducing the relative risk by 7-8 per cent.
More than 11 million men and women in the United States struggle with an eating disorder. To raise awareness and understanding of these devastating diseases, Eating Recovery Center, a behavioral hospital focused on comprehensive treatment and sustainable recovery for eating disorders, has developed this Blogger’s Guide to Eating Disorders. This guide offers information and resources to support your stories about America’s deadliest mental illness.
For downloadable eating disorder resources, please visit http://bit.ly/8ZbVAO.
Long term spinal cord injury (SCI) and diabetes? Some research suggests the two go hand in hand with as
many as 20 percent of spinal cord injured people having adult-onset diabetes. If you have an SCI, what should
you know about diabetes?
"An introduction to the most common forms of eating disorders, with essential information about causes, risk factors, and treatment options. An excellent starting point for anyone who is struggling with an eating disorder, or who suspects that someone they love is in danger."
Causes Of Eating Disorder | Solh Wellness App.pdfSolh Wellness
According to research , around 9% of the world population is suffering from Eating disorder. Solh Wellness talks about Eating Disorder Types and Causes in detail.
Improving the lives of those suffering from psychiatric and behavioral disorders is what we strive to achieve at the CNS Center of Arizona. Our psychiatrists specialize in severe and dual neuropsychiatric disorders. They understand and care for the patient medically, emotionally, socially, and spiritually. They teach what they know to patients and their families. This approach, we have found, helps empower patients to manage their lives, over time, and achieve the best outcome possible. Our approach at CNS Center of Arizona is a collaborative model of care involving other professionals and therapists. We expect patients who are currently in therapy to maintain contact with their primary therapist. CNS Center AZ
http://www.cnscenteraz.com
MedicYatra provides the safe & best Weight loss treatment and procedure at its affiliate & trusted hospitals & clinics in various metro cities of India, like Mumbai, Delhi, Bangalore, Chennai, Pune etc.Our Associate Board certified doctors are extensively trained and vastly experienced and have performed hundreds of such cases at our state of the art JCI accredited hospitals & Clinics. Our aim is to provide you the best of the services at the most affordable costs. Don't forget to say hi at info@medicyatra.com
Malignant Mixed Mullerian Tumor – Case Reports and Review ArticleApollo Hospitals
Malignant mixed mullerian tumors are very rare genital tumors. They are biphasic neoplasms composed of an admixture of malignant epithelial and mesenchymal elements. In descending order of frequency they originate in the uterus, ovaries, fallopian tubes, cervix and vagina. Also they arise denovo from peritoneum. They are highly aggressive and tend to occur in postmenopausal low parity women. Because of rarity, there is as such no treatment guidelines available. Multimodality treatment in the form of radical surgery followed by adjuvant chemotherapy or radiotherapy or combined chemoradiation gives a better prognosis & outcome. Two case reports of such tumors, one from ovary and other from penitoneum are presented along with the review of literature.
Intra-Fetal Laser Ablation of Umbilical Vessels in Acardiac Twin with Success...Apollo Hospitals
To interrupt blood supply to the acardiac twin in a case of TRAP sequence of monochorionic diamniotic multiple pregnancy to allow for continuation of the normal twin.
Breast Cancer in Young Women and its Impact on Reproductive FunctionApollo Hospitals
Breast cancer is the most common cancer in women in developed countries. Chemotherapy for breast cancer is likely to negatively impact on reproductive function. We review current treatment; effects on reproductive function; breastfeeding and management of menopausal symptoms following breast cancer.
Turner syndrome (gonadal dysgenesis) is one of the most common chromosomal abnormalities occuring 1 in 2500 to 1 in 3000 live-born girls. It is an important cause of short stature in girls and primary amenorrhea in young women that is usually caused by loss of part or all of an X chromosome. This review briefly summarises the current knowledge about the syndrome and the management strategies.
Due to pregnancy thyroid economy is affected with changes in iodine metabolism, TBG and development of maternal goiter. The incidence of hypothyroidism in pregnancy is quite common with autoimmune hypothyroidism being the most important cause. Overt as well as subclinical hypothyroidism has a varied impact on maternal and neonatal outcome. After multiple studies also, routine screening in pregnancy for hypothyroidism can still not be recommended. Management mainly comprises of dosage adjustments as soon as pregnancy is diagnosed based on results of thyroid function tests. The aim should be to keep FT4 at the upper end of normal range.
Growth Hormone Deficiency (GHD) can persist from childhood or be newly acquired. Confirmation through stimulation testing is usually required unless there is a proven genetic/structural lesion persistent from childhood. Growth harmone (GH) therapy offers benefits in body composition, exercise capacity, skeletal integrity, and quality of life measures and is most likely to benefit those patients who have more severe GHD. The risks of GH treatment are low. GH dosing regimens should be individualized. The final decision to treat adults with GHD requires thoughtful clinical judgment with a careful evaluation of the benefits and risks specific to the individual.
Advances in the management of thalassemia have led to marked improvements in the life span and quality of life of children and young adults. This poses new challenges for the treating physicians. There is now increasing recognition that thalassemics have impaired bone health which is multifactorial in etiology. This paper aims to highlight the factors that predispose these patients to osteoporosis and suggests measures to minimise the impact on bone health.
Laparoscopic Excision of Foregut Duplication Cyst of StomachApollo Hospitals
Retroperitoneal gastric duplication cysts lined by ciliated columnar epithelium are extremely rare lesions and its presentation during adulthood is a diagnostic challenge for treating clinicians. This entity often resembles cystic pancreatic neoplasm, retroperitoneal cystic lesions and sometimes as an adrenal cystic neoplasm. Correct diagnosis on the basis of radiological investigation is difficult and histopathologic analysis. We report a case of gastric duplication cyst in a 16year old girl that mimicked as a retroperitoneal /pancreatic /adrenal cystic lesion and was successfully managed by laparoscopy.
Occupational Blood Borne Infections: Prevention is Better than CureApollo Hospitals
Viral infections like HIV, hepatitis Band C virus pose a big risk to the contacts of individuals with high risk behaviour as well as to the attending health care workers. Blood, semen, vaginal and other potentially infectious materials can transmit the infection to the susceptible contacts. Universal precautions should be strictly implemented during clinical examination, laboratory work and surgical procedures to prevent transmission to the health care providers. Health care workers should receive vaccination for hepatitis B infection. An inadvertent exposure should be managed with proper first aid and infectivity of the source and severity of exposure should be assessed. Severity of exposure is based on the nature and area of exposed surface, mode of injury and volume of infective material. Post-exposure prophylaxis (PEP) should be started as soon as possible after a proper counseling about the effectiveness of post-exposure prophylaxis, side effects and risk of carrying the infection to his familial contacts and its prevention.
Evaluation of Red Cell Hemolysis in Packed Red Cells During Processing and St...Apollo Hospitals
Storage of red cells causes a progressive increase in hemolysis. Inspite of the use of additive solutions for storage and filters for leucoreduction some amount of hemolysis is still inevitable. The extent of hemolysis however should not exceed the permissible threshold for hemolysis even on the 42nd day of storage.
Efficacy and safety of dexamethasone cyclophosphamide pulse therapy in the tr...Apollo Hospitals
Various drugs used to treat pemphigus can cause remission, but none can provide permanent remission as relapses are common. With the introduction of DCP in pemphigus in 1984, patients started being in prolonged/permanent remission. This study was done to compare the efficacy of DCP to oral corticosteroids and cyclophosphamide in combination.
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)Apollo Hospitals
Severe skin adverse drug reactions can result in death. Toxic epidermal necrolysis (TEN) has the highest mortality (30–35%); Stevens-Johnson syndrome and transitional forms correspond to the same syndrome, but with less extensive skin detachment and a lower mortality (5–15%). Hypersensitivity syndrome, sometimes called Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), has a mortality rate evaluated at about 10%. It is characterised by fever, rash and internal organ involvement. Prompt diagnosis is vital, along with identification and early withdrawal of suspect medicines and avoidance of re-exposure to the responsible agent is essential. Cross-reactivity to structurally-related syndrome caused by Carbamazepine medicines is common, thus first-degree relatives may be predisposed to developing this syndrome. We report a case of DRESS secondary to use of Carbamazepine.
Difficult Laparoscopic Cholecystectomy-When and Where is the Need to Convert?Apollo Hospitals
Laparoscopic cholecystectomy has now become the treatment of choice for the gall bladder stone. With increasing experience, surgeon has started to take more difficult cases which were considered relative contra indications for laparoscopic removal of gall bladder few years back.
We conducted this study at our hospital and included all laparoscopic cholecystectomy done from May'08 to January'10. Total time taken in surgery, conversion rate and complication rate were analysed. Factors making laparoscopic cholecystectomy difficult were also analysed. We defined difficult laparoscopic cholecystectomy when we found -dense fibrotic adhesions in and around Callot's triangle, gangrenous gall bladder, empyma, large stone impacted at gall bladder neck, contracted gall bladder, Mirrizi's syndrome, h/o biliary pancreatitis, CBD stones, acute cholecystitis of <72 hrs duration.
Out of 206 cases done during above period, 56 cases were considered difficult. Only two cases were converted to open.
With growing experience and technical advancement surgery can be completed in most of the difficult cases. This is important because recently it is shown in literature that laparoscopic cholecystectomy is associated with less morbidity than open method irrespective of duration of the surgery.
Deep vein thrombosis prophylaxis in a tertiary care center: An observational ...Apollo Hospitals
Deep vein thrombosis (DVT) is a major health problem with substantial mortality and morbidity in medically ill patients. Prevention of DVT by risk factor stratification and subsequent antithrombotic prophylaxis in moderate- to severe-risk category patients is the most rational means of reducing morbidity and mortality.
The spread of dengue and dengue haemorrhagic fever is increasing, atypical manifestations are also on the rise, although they may be under reported because of lack of awareness. We report two such cases of dengue hemorrhagic fever with hepatitis, intraocular hemorrhage, ARDS and myocarditis.
A 71-year-old male presented in ENT department with dysphagia for last three weeks, more to solids than liquids. He had a hard bony bulge in the posterior pharyngeal wall on palpation and hence was referred for an Orthopaedic opinion. Lateral radiograph of the cervical spine revealed diffuse ossification of the anterior longitudinal ligament. This ossification was extending almost half the width of the cervical body from its anterior body at C1 and C2 vertebra level.
Pediatric Liver Transplant (LT) is now an established procedure for End Stage Liver Disease (ESLD) with biliary atresia being the commonest indication. Intensive pre-transplant evaluation, nutritional buildup and immunization are the fundamental pre-requisites of a successful LT. With improvement in surgical micro-anastomotic techniques and superior immunosuppressive regimens the success rate of pediatric LT is in excess of 90%. Most of the transplants in our country however are Living related, due to which a fairly large number of children expire awaiting a donor liver. There should be a concerted effort to evolve the cadaveric donation program, so that majority of the children are benefitted.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
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Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
ENLIGHT: A Quarterly Bariatric Support Group System
1. Volume1 Issue1
enlight
21 March 2013
Chennai . India
QUARTERLY
NEWSLETTER
Apollo launches its 1st Bariatric Center of Excellence in November 2012
contents inside:
Chennai tops obesity survey 2
”Enlight” support group
3
Success Stories 3
Battle on the Bulge 4
Must eat nutrients for winter 5
Control your mind 5
Metabolic Syndromes 6
Obstructive Sleep Apnea 7
Easy lifestyle routines 7
from the surgeon’s desk: Welcome to Apollo Bariatric Institutes. With alarming increase in prevalence of obesity
and its consequences, we are at the brink of war with the most threatening lifestyle
Dr. Rajkumar Palaniappan disease of this age. The aim of this newsletter initiative is to spread awareness about this
looming issue and its management possibilities. We at our institute provide a holistic
2013
approach to the management of obesity and its metabolic consequences with focus on
all aspects including nutritional management, counseling, wellness program and surgical
management to combat any type of weight & its related syndromes.
2. what’s hot & what’s not: Indians seem to be more vulnerable to lifestyle changes. The culprit may be what is
called the 'thrifty genotype'. According to this theory, Indians, are genetically adapted
obesity facts to scarcity in calories due to just one meal and rarely two meals a day and follow a
“famine–feast cycle”. This was true until two decades ago when suddenly our country
2013
became richer and three meals became affordable. As a result, their bodies can't cope
over-indulgence, and it takes only a small increase in daily calories for their metabolism
to tip over into obesity and diabetes. This made Indian prone for alarming weight gain
and its issues more rapid than other countries when added with sedentary lifestyle.
Chennai tops national obesity survey amongst 11 metropolitan cities
70% of people above their ideal weight
A C Nielson
For Johnson & Johnson Medical suffer from at least 1 coexisting disease
condition. In Chennai, 51% of all people
experts believe:
above their ideal body weight suffer from at People fall prey to advertisements for
least one co morbidity, associated with
quack treatments than scientific treatments.
obesity* but nearly 33% are unaware of
existing conditions since they have never People fail to realize that Obesity is a
consulted a doctor making it the most unsafe disease and it can be treated scientifically.
of all locations for obesity. Average duration
of suffering from any coexisting indication/ Psychologically the consumer is
illness is 3 to 4 years with incidence of constantly feeling that they have
hypertension 52%, heart diseases in 45%,
type 2 Diabetes in 42%, sleep apnea in attempted to lose weight.
39%, heart burn in 38% and arthritis in
Consumers feel that losing weight
35% of overweight patients. Other common
illness include polycystic ovarian disease, means giving up food/ drinks and stop
gout, liver diseases, menstural irregularities, living, hence they prefer the way they are.
depression and thyroid deficiency in up to
20% individuals. There are several expenses associated
India has been the focus of interest for
with weight loss measure like costs related
WHO in the recent years for the main What is more alarming is that
reasons, namely obesity. There have been significantly higher number of respondents to healthy eating, gym and travel costs,
reports on obesity being endemic in India have never done anything nor intend to do medical costs for ailments, absenteeism
with south being more affected by this anything in future about their weight and co-
from work. To add, are indirect costs of
lifestyle disease. Recently a research to existing illness. 43% of obese individuals
understand the current status and trends in have never done anything to tackle their “Missing out on the essence of life”.
the management of obesity in Chennai and problem of obesity. In spite of being aware
south India was conducted by A.C. Nielsen of several weight loss options, we find People look for shortcuts and especially
for Johnson & Johnson, Medical. limited takers for those options. While 82% those which are economical. Such options
believe that obesity is caused due to eating,
don’t give a sustained weight loss solution
A survey conducted in 11 metropolitan we find only 25% practicing dieting. When
cities across the nation revealed Chennai asked about reasons for not doing anything and after a failure they are resistant
emerging as the obesity capital. 38% of currently, paucity of time (46%), towards trying anything new.
Chennai’s population was found to be comfortable / happy the way I am (27%),
above its ideal weight of which 12% are need a quick solution to the problem and Consumers may idolize film/ sports
obese and 3% are morbidly obese. 6% of there are no quick fix methods (21%) were personalities but friends, spouse, relatives
total obese population in top 11 cities is on the most significant responses for their
the verge of being morbidly obese with their weight and co-morbid issues. However play a key role in persuading people to
BMI in the range of 35 – 37.5 of which 23% among overweight and obese the urge/ undertake any weight loss measures.
are from Chennai. More so 40% of morbidly need to lose weight is missing.
obese across these 11 locations have their
BMI >50, of which the highest contribution is The expenses from consumers point of
again from Chennai at 17%. Obesity is more view may seem minimal but its all about
prevalent in women (16%) as compared to what they “remember”. Right from food,
men (13%) and prevalence increases with living, travel whatever they must have spent
age with significantly more with the age towards weight loss they do not correlate
group over 31 years. anything as an expense on the treatment of
obesity. Hope of being successful,
Overweight individuals feel that the top motivation, cost & their current health status
three causes for prevalence of obesity* in are refraining morbidly obese from losing
Chennai are –Irregular eating habits (62%), weight. Most consumers try inexpensive
eating oily or fatty food (53%) and lack of options , and less than 1% patients are
physical activity or sedentary lifestyle aggressively follow some scientific treatment
(43%). Basically begins as a problem, grows and that is why more than 99% are failures.
into an emotional burden and then Chennai fast needs to wake up to obesity
transcends into a disease state. and its deadly consequences.
3. “ENLIGHT” Bariatric support group initiative for obese individuals
To aid in patient’s fight management, pre and post- surgical This highly beneficial session is planned
patients, support is absolutely critical to once every quarter and the next session is
against obesity and long-term sustained weight loss and slated on June 8th. Regardless of whether a
metabolic syndromes.. maintenance. Support group meeting patient is in the process of considering
attendance directly increases the chances of bariatric surgery, just prior to the surgery or
We recognize that obesity is a short and long term patient success post post-surgery, they are welcome to attend the
debilitating disease of mind, body and spirit bariatric surgery. sessions and are highly encouraged to bring
and must be addressed holistically to their loved ones along as well. The success
achieve long-term success. Patients post- We at Apollo Hospitals has taken this of this surgery also hinges on the support
surgery realize that surgery will not seriously and started a quarterly support the patient receives at home, which is why
miraculously eliminate the emotional or group system named “ENLIGHT”. We educating the family is a priority for us.
psychological trauma that morbid obesity conducted our first support group meeting
had inflicted on them for years. They are on the 8th of March and was attended by
also in the process of developing an entirely
new way of looking at food as well as their
20 patients (8 pre-op and 12 post-op). Our
support groups are in place to assist patients
“enlight” features:
bariatric surgery experience, both on a with addressing more immediate and long- Know about obesity & co-morbidities
personal and professional basis. term questions and needs including the most
Understand types of bariatric Surgery
beneficial diets, exercise regimens, body
Support groups constitute an integral contouring options, dealing with lifestyle Nutrition and lifestyle master classes
part of vision to provide safe, effective and changes that follow bariatric surgery, , Pre & Post operative patient interactions
efficacious care to the patient population. importance of adhering to the medication
Research has consistently demonstrated that Sharing of experience with obesity
regimen strictly, ways to bolster one’s
all types of ongoing weight management emotional, mental, psychological and Quarterly meeting with Bariatric team
plans, including people on diet, medical spiritual health.
what’s hot & what’s not: India has the second largest diabetic population in the world with seven crore people
and equal urban (25.4%) and rural (25.2%) distribution of obesity among them. An
co-morbidty facts estimated increase of more than 50% is predicted in the next 15 years making the count
to around eleven crore and to become the diabetic capital of the world by 2030.
2013
India is also tipped to be having the second largest hypertensive population with 11
crore individuals and predicted to become the hypertensive capital by 2025 with an
estimated disease population of 21 crore. At present 20% of all deaths in India are
either obesity or metabolic disease related.
VENUGOPAL is one happy
man after losing 64 kg..
I’m a professional working with Ashok
Leyland as Deputy manager. I was always
on the plump side, slowly started adding
weight in years due to work demands,
irregular diet habits and sedentary lifestyle.
I was weighing 140 kg in 2011 and was not
even able to walk properly. My self esteem
and confidence were low and was even
suffering from depression which started
affecting my performance at work.
Though i was aware of Bariatric surgery, I
was very worried to go under the knife. That
is when i read about the scarless SILS
technique of Bariatric surgery at Apollo
Hospitals, Greams Road. I underwent
surgery in March 2011 in spite of negative
comments from relatives and friends. After
the surgery i lost an amazing 64 kg in 8
months. Now I feel more healthier and more
free, have better self-confidence, self-esteem
and performance based promotion at work.
In simple terms the surgery has turned my
life upside down for the best.
It’s been close to 2 years since surgery and i
still stand at 76 kg. I am proud to have made
one of the best decision in my life.
4. what’s hot & what’s not: Bariatric Surgery: Battle on the Bulge
BMI facts Dr.Rajkumar Palaniappan Gastric bypass, which combines
restrictive and malabsorptive surgery
2013
Bariatric Surgeon
techniques, is the most frequently performed
Bariatric surgery is a surgical bariatric procedure and is the GOLD
procedure wherein the size of the stomach is standard in Bariatric surgery. In this
curtailed and / or intestines are bypassed procedure, stapling creates a small (15 to
leading to reduced consumption of calories 20 cc) stomach pouch. The remainder of the
and thus aiding in weight loss. Over the last stomach is not removed, but is completely
BMI = Weight in kg
decade, weight loss surgery has been stapled and divided from the lower stomach.
Height in m2 continually refined to improve results and The small intestine is then divided just
minimize risks. Today, bariatric surgeons beyond the duodenum and a connection
As per IFSO-APC guidelines, BMI for
have access to a substantial body of clinical with the new, smaller stomach pouch is
Indians is reduced by 2.5 due to the
data that supports the use of surgery as a constructed (see picture). The length of
occurrence of potentially life
safe and effective weight loss treatment either segment of the intestine can be
threatening co-morbidities at an early
when other methods have failed. increased to produce lower or higher levels
BMI. Less lean body mass, more
body fat and central obesity are of malabsorption. An analysis of clinical
People who fall in the Grade III studies reported an average excess weight
postulated to be the reasons.
category of obesity stand most eligible, loss of 70 – 80 % over a period of 2-3
patients in Grade II obesity with one or years. It is shown to help resolve type 2
more co-morbidities may also opt for diabetes, high blood pressure, and
Underweight < 18.4
bariatric surgery. Bariatric surgery leads to obstructive sleep apnea, and to help
drastic weight loss, in a significantly smaller improve high cholesterol with success rates
Normal 18.5 - 22.4 time frame. As it is exclusively done by more than 80%.
laparoscopy, recovery is faster with less
Overweight 22.5 - 27.4 post-operative complications. It also requires The bariatric procedure can successfully
less effort to lose weight. More importantly start patients on the road to recovery from
Obesity I 27.5 - 32.4 bariatric surgery significantly increases the clinically severe obesity, but surgery alone
life span of an obese individual will not ensure long-term success. Most
simultaneously ridding of co-morbidities. The patients lose more than half of their excess
Obesity II 32.5 - 37.4
choice of surgery depends on patients BMI weight in the first year and continue to lose
& co-morbidities. weight after this point. Successful habits
Obesity III > 37.5
include eating three small, well-balanced
Surgical procedures promote weight meals, and a maximum of one snack a day.
loss by two different ways: Patients tend to gain weight back if they start
1. By decreasing food intake eating larger portions, graze, consume high
(restriction) by surgeries that limit the fat or "junk" foods, or drink high-calorie
amount of food the stomach can hold by beverages. A program of regular exercise is
closing off or removing parts of the stomach. very important for promoting and
NOTE: The majority of patients report early maintaining weight loss. Patients who
satiety and, and hunger is lost from 30 – 70 exercise 45 minutes at least three times per
% depending on the procedure. The most week lose an average of 18% more excess
popular in India and commonly used weight than patients who do not exercise.
restrictive procedure is sleeve gastrectomy
(see picture). During this procedure a thin
vertical sleeve of stomach like a hockey stick techniques:
is created using a stapling device. This
sleeve will typically hold between 80-100 Conventional Laparoscopy
ml. The excised portion of the stomach is Surgery is done through three or more
removed. In clinical studies across India,
tiny keyholes through the abdomen.
patient lost an average of 60 – 70% of their
excess weight. It is also shown to help
Single Incision Laparoscopic Surgery
resolve high blood pressure and obstructive
sleep apnea, and to help improve type 2 Surgery is done through a single hole
diabetes and hyperlipidemia. However long in the belly button and there wont be
term durability is not proved due to paucity
any visible scar in the abdomen.
of data and being a new procedure.
2. By causing food to be poorly Robotic Surgery
digested and absorbed (malabsorption).
Surgeon makes a direct connection from the Similar technique as conventional
stomach to a lower segment of the small laparoscopy, with 3D vision, better
intestine, bypassing the duodenum, and
precision, control, safety, and less pain.
some of the jejunum. NOTE: Vitamin and
mineral rich high protein intake will be Endoluminal Surgery (to be launched)
required for life to prevent the problem of
For low BMI patients where surgery is
nutritional deficiencies. Although results are
more predictable and manageable, side performed through endoscope.
effects persist for some patients.
5. control your mind Must eat low calorie nutrition for winter
When we aim for our goals, we take
Dr.Deepa Agarwal
into consideration many factors: do Bariatric Nutritionist
we have the necessary talent and Seasonal eating is a healthier bet! As
abilities to achieve them? Are we the winter’s chill sets in, we find ourselves
reaching for cozy, comfort foods that equate
motivated enough? What obstacles do
warm ovens with warm hearts. Winters can
we have in our way, and how do we be hard on health with most people staying
overcome them? indoors. With days getting shorter, outdoor
exercise becomes difficult and people
However, our perception of these
engage in more passive activities like
factors can make a big difference to watching television and reading. Studies
the way we achieve. Let’s assume that have suggested that there is an increase in
aches and pains during the winter, along
our goal is weight loss. Perhaps we with an increase in functional impairment
are not motivated to eat right because associated with seasonal depression. An
increase in appetite is also reported, with Tea and coffee produce warmth but should
we think, “The holidays are around
the festive season leading to temptation to be consumed in moderation. Of course some
the corner, and I can start dieting indulge. comfort foods will always need to be eaten
once they’re over”. Or perhaps “I in strict moderation - for example puddings
Nature has its own way of keeping the loaded up with custard or cream, cakes,
have too much stress in my life right
body warm. The heat can be generated biscuits, chocolate and crisps.
now, and eating food that I enjoy is from within the body as well as from food
one of the few pleasures I can get.” that raises the body’s temperature to help it Eat healthy during winters and include
cope. The body needs to burn more calories foods that'll keep you snug and steady at
Such thoughts can slow us down, or
to keep warm and hence there is a need to the same time. Exercise can also give you a
prevent us from achieving our goals; eat judiciously. Certain foods have a more similar mental high to eating comfort food. If
but, by controlling our minds, we can warming effect than others. you can, wrap up warm and go for a brisk
walk outside every day.
work toward overcoming these Apart from the traditional Indian whole
negative thoughts and procrastination. grain cereals besides wheat and rice,
So, try replacing them with positive
include bajra, oats, maize or corn. Millets what’s hot & what’s not:
can be used to make hot porridge. Whole
thoughts. For instance, the holiday pulses and legumes like beans, soyabean nutrition facts
2013
example can be turned into, “I know and lentils can be used in soups and stews.
Winter is an excellent time to incorporate
the holidays are coming, so let me use
ginger, garlic, cinnamon, turmeric and
this as an opportunity to test my cloves into one’s daily diet. In addition to
ability to control my eating habits”. their warming effect, they contain
phytonutrients, anti-microbial and anti- Calling all almond lovers! A new study
We can also try to look at the positive published in the American Journal of
inflammatory properties that help fight
side of stress as well: “I realize I’m infections and disease. Garlic has special Clinical Nutrition found that almonds
decongestant, antibiotic and antifungal have 20% fewer calories than
feeling stressed, so maybe I could try
properties to fight coughs, colds and originally thought. The results found
talking to someone about the issue to sinusitis. Ginger increases peripheral that one-ounce serving of almonds has
see if they can help. I want to get circulation. Almonds, walnuts, peanuts, 129 calories as opposed to 160 that’s
black and white sesame seeds and flax currently listed. Interestingly, it has
pleasure from more aspects of my life
seeds are nutrition-packed for cold days. nothing to do with the composition -
than just eating!”. They are rich in heart-healthy fats, fiber, rather, the way we metabolize it.
magnesium and vitamin E. Honey and Recipe to Try:
jaggery are natural substitutes for sugar and Honey and Fennel Glazed Almonds:
have warming effects. Dark green leafy Preparation: Preheat oven to 300°F.
vegetables like Mustard greens and Melt unsalted butter (2 tbsp) in a
amaranth greens (bathua) are good sources large skillet on medium heat. Stir in
of iron and folate and help maintain good honey (3tsp), water (1 tbsp), salt (1
haemoglobin levels. Vitamin C loaded foods 1/4th tsp) and ginger (1/4th tsp) .
like carrots, pumpkin, turnips, cabbage, Stir in almonds ( 2 cups) and fennel
tomatoes, oranges, guava, lime and amla ( 1tsp), and remove from heat.
help fight infections like the common cold Spread almonds onto foil, and bake
and flu. Lean meats, fish, and poultry are 25 to 35 minutes, stirring once, until
high biological value protein foods and are almonds are golden (cut one open to
associated with increased heat production test). Transfer almonds on foil to a
and higher thermogenesis. Hot soup, masala rack, cool completely and serve.
tea, green tea, and hot water with Nutrients: Calories:205, Fat:2.6g,
condiments help keep the body hydrated Protein:6g, Carb:11g, Fiber:4g
and maintain body temperature.
6. Metabolic syndromes: Killer diseases that complicate obesity
Terms like metabolic syndrome, Insulin
Dr.Boochandran
Resistance Syndrome, Syndrome X are used
Consultant Endocrinologist
for a group of conditions predisposing to diabesity
Metabolic Syndrome is a combination Type 2 DM and Atherosclerotic Vascular
of medical condition and disorder, when Diabesity, a new terminology coined
Disease.
occurring together invokes the risk of for patents suffering from Obesity and
Diabetes and Cardiac Disease. According "Metabolic syndrome" dates back to at Diabetes is today’s most blatantly
to the International Diabetes Federation least the late 1950s, but came into common
(IDF) – the definition of Metabolic visible – yet most neglected public
usage in the late 1970s to describe various
Syndrome is Central Obesity (Waist associations of risk factors with diabetes, health problem. The link between
circumference with ethnicity specific values) that had been noted as early as the 1920s. obesity and diabetes is firmly
and any of the following:
established and threaten the health,
• The Marseilles physician Dr. Jean Vague,
• Raised triglycerides > 150 mg/dl in 1947, made the interesting observation well-being and economic welfare of
• Reduced HDL < 40 mg/dl that upper body obesity appeared to
virtually every country. Since organ
• Raised BP Systolic BP >130 mm Hg predispose to diabetes, atherosclerosis,
Diastolic BP > 85 mm Hg gout, and calculi. damage is inevitable if not controlled,
• Raised Fasting Glucose >100 mg /dl • In 1977, Haller used the term "metabolic early multi modality treatment should
syndrome" for associations of obesity,
If BMI > 30 kg /m2, waist circumference be considered, especially in India
diabetes mellitus, hyperlipoprotinemia,
need not be measured. High sensitivity C- hyperuricemia and steatosis hepattis when which is tipped to become the obesity
reactive protein has been developed and describing the additive effects of risk and diabetic capital by 2025.
used as a marker to predict Coronary factors on atherosclerosis.
Vascular Disease in Metabolic Syndrome.
In a recent population based study from Chennai, the metabolic syndrome prevalence
what’s hot & what’s not: was 18.3% by ATPIII criteria. In Northern India, the prevalence (ATPIII) was 35% in an
metabolic facts industrial population and 24.9% in a community based study. Metabolic Syndrome
causes higher incidence of cardiovascular disease than patients with diabetes.
2013
Congestive Heart Disease is 50% more common in patients with metabolic syndrome,
37% have premature artery disease at age 45, particularly in woman.Its prevalence
increases with age and is higher in men than in women in south India. Almost 1% of
children born in India are found to be suffering from “Inborn Metabolic Syndrome”.
• In 1988, in his Banting lecture, Dr. Gerald The pathophysiology is extremely
M. Reaven proposed insulin resistance as complex and only partially understood. The
the underlying factor and named the important factors predisposing to Metabolic
constellation of abnormalities Syndrome Syndrome are Obesity, genetics, endocrine
X. Reaven did not include abdominal disorders such as PCOS, sedentary lifestyle.
obesity, which has also been A number of inflammatory markers are
hypothesized as the underlying factor, as elevated such as C-reactive protein,
part of the condition. fibrinogen, interleukin-6, TNFα and others.
In a study done in 2010, by Vinayaka With appropriate cardiac
Mission University, Salem, South India, 1568 rehabilitation, change in lifestyle (Eg. Diet,
patients with Metabolic Syndrome were physical activity, weight reduction, if needed
studied. Waist circumference, dyslipidemia medications), the prevalence of the
and GTT were assessed and it was found Syndrome can be reduced. However in
that 33% of males and 27% of females were country like ours, people seek medical
found to have Metabolic Syndrome. It was attention only very late when the symptoms
also found that it was more prevalent in men had already become irreversible.
than in women. Compared to the European
population, Asian Indians have a lower BMI Since metabolic syndrome with obesity
but had a greater waist to hip circumference accounts for more than 20% of all causes of
ratio. death n India, IDF through its Asia Pacific
Chapter (APC) has postulated guidelines to
In another recent study, done in Urban consider Bariatric surgery as an effective
India by Hinduja Hospital Mumbai, a total option. The point statement issued in 2011
of 548 subjects were screened in a cardiac states that Bariatric/GI metabolic surgery
evaluation camp and it was found that SHOULD be considered for the treatment of
Metabolic Syndrome was present in 19.72% T2DM or metabolic syndrome for patients
of population, 79% had a Body Mass Index who are inadequately controlled by lifestyle
of more than 23. Raised triglycerides & low alternations and medical treatment for
HDL were found more in males than in candidates with BMI≥30 and MAY be
females. Incidence of metabolic syndrome considered as a non- primary alternative to
increased with increase in BMI. treat candidates with BMI ≥ 27.5.
7. Obesity and Snoring: Potential life threatening Obstructive Sleep Apnea
Forty-five per cent of normal adults 3. Long soft palate and/or uvula. They
Dr.Narasimhan
snore at least occasionally, and 25 per cent narrow the opening from the nose into the
Consultant Pulmonologist
are habitual snorers. The problem is more throat. As it dangles, it acts as a noisy
SNORING is a symptom of a serious frequent in males and overweight persons, flutter valve during relaxed breathing.
disorder called sleep apnea. Sleep apnea is and usually grows worse with age. They 4. Obstructed nasal airways. A stuffy or
characterised by repeated collapse of the may wake up frequently at night resulting in blocked nose requires extra effort to pull
upper airway during sleep with consequent sleepiness and fatigue during the day. This air through. This creates an exaggerated
cessation of breathing. A person who snores could also result in serious medical problems vacuum and pulls together the floppy
is often an object of ridicule and causes like hypertension and in some cases even tissues of the throat, and snoring results.
sleepless nights for others. This problem is cause sudden death.
worse when one is a frequent traveller. A common question is whether OSA is
The main cause is an obstruction to the a genuine problem and if there is a cure.
free flow of air through the passages at the OSA can be cured. Equipments like BIPAP
snoring facts: back of the mouth and nose. This area, (Bilevel positive airway pressure) and CIPAP
where the tongue and upper throat meet the (Continuous positive airway pressure) help
Many do not realize that a person is
soft palate and uvula, is collapsible. Snoring keep the airways open and in some cases
breathing only when he is snoring. The occurs when these structures strike each surgery can solve the problem. But a
sudden cessation of snoring followed by other and vibrate during breathing. People detailed ENT examination and a sleep study
who snore may suffer from: are mandatory before surgery. BIPAP and
heavy snoring occurs because of the signal 1. Poor muscle tone in the tongue and CPAP are to be used on a long-term basis. If
to brain from oxygen-starved organs. This throat. This happen during deep sleep. the patient is suffering from obesity as well,
2. Excessive bulkiness of throat tissue in Bariatric surgery mostly cures OSA. Even
results in fragmented and daytime sleep.
obese individuals. Children with large people using PAP for decades get relieved
tonsils and adenoids often snore. of symptoms after weight loss surgery.
7
0
what’s hot & what’s not: Nicolas V Christou studied the hypothesis that bariatric
surgery reduces long-term mortality in morbidly obese
% 5 yr MORTALITY
surgery facts patients. Bariatric surgery resulted in significant reduction 6.17
in mean percent excess weight loss (67.1%, P < 0.001).
2013
They had significant risk reductions for developing cancer, 0.68
cardiovascular, endocrine, infectious, psychiatric, and
mental disorders compared with controls which translates
to a reduction in the relative risk of death by 89%. Control Bariatrics
Easy daily lifestyle routines to lose excess weight
become more mobile. If you move around be active after supper, thus burn more
Ms. Krithvi Shyam
Clinical Psychologist enough, you can reduce the risk of all calories before going to bed and thus stay
lifestyle diseases and burn up to 750 more slimmer. They will be up early and
There has been a misconception among calories per day without even dieting or continue with breakfast during the peak
public that dieting is enough to lose weight. hitting the gym. It requires you to rethink all metabolic activity. This helps them be more
And people are literally advised to starve in your habits and find new, more active ways fit and active and help them burn more. The
the name of dieting. Dieting alone cant help to get through the day, making your own above lifestyle changes can add up to
you lose weight for long. It is not the healthy cup of tea than asking your maid or office burning of 1500 calories apart from an
way to lose weight too. Unfortunately boy, or going for thrice a week shopping insensible loss of 500 calories, accounting
slimming center use artificial fat dissolving instead of once a week bundled purchase. for the expenditure of 2000 calories intake
techniques that are temporary and diet Other major issue is the timing of meals. Our in a healthy Indian diet. This is simply how
charts with far less-than-required calorie body will have the least calorie-spending you go from being couch potatoes to muffin-
intake that are unhealthy. You might lose rate between 8 pm and 6 am. If the person top blasting fitness freaks.
weight for the first few months, but further has an erratic meal timing, body either will
loss will be arrested because the body be depleted of calories due to long gap
reduces burning its calories. Add exercise to between meals, or because of you feeding
it, you will lose energy and get tired early. in with more calories during the time of least
Your performance at work will also be metabolic rate, your body tend to store most
compromised. Life style changes are the real of the calories than spending it. Also there
healthy way to keep check at your weight will not be much of activity after you meal
loss program. Add responsible eating and late in the night, which will not allow you to
exercises, you will lose weight the right way, spend the calories taken in. If you can
the healthy way. regularize your meals to the time when your
body is at its peak metabolism potential, ie 7
Increase your daily physical activity am, 12 pm, 7 pm, you will burn up to 500
routine. Incorporate standing and walking calorie more than before without even
activities as a part of you home and work moving a muscle. Morning people tend to
activities. The first and foremost change is to eat early, and give themselves a chance to
8. editor: secretariat:
Dr. Rajkumar Palaniappan Bariatric Institute
Apollo Hospitals
co-editors: 21 Greams Lane
Dr. Boochandran Chennai 600006
Dr. Deepa Agarwal India
contacts:
tel: +91 44 42041788
mob: +91 7299952999
fax: +91 44 28294429
email:
bariatrics@email.com
website:
www.apollohospitals.com