The document describes Earth's major subsystems which include the atmosphere, hydrosphere, lithosphere, and biosphere. It provides details about each subsystem, such as the atmosphere containing the air and essential gases for life, the hydrosphere containing all of Earth's water, the lithosphere being the solid part of Earth, and the biosphere composed of all living things that interact to support life. It also defines key terms like environment, ecosystem, and ecology.
Environment that exist around us; supports our existence. Its little about our environment, how we all are co-related with our every little thing about environment.
the atmosphere, (The cover of the air)
the hydrosphere, (water bodies)
the lithosphere (the earth’s crust)
the biosphere. (the life layer)
Environmental Engineer’s role
Environment that exist around us; supports our existence. Its little about our environment, how we all are co-related with our every little thing about environment.
the atmosphere, (The cover of the air)
the hydrosphere, (water bodies)
the lithosphere (the earth’s crust)
the biosphere. (the life layer)
Environmental Engineer’s role
Environment is what is surrounding us, whether living or non-living. Things wecan see and feel, things we cannot see but feel e.g. air, people and theirpractices and landforms also the weather
Environment - Class 7 - Geography (Social Studies)AnjaliKaur3
This PPT is helpful for class 7 students and for teachers looking for teaching aids. This topic is about Environment and I have explained the same in a very simple and interesting manner.
Environment is what is surrounding us, whether living or non-living. Things wecan see and feel, things we cannot see but feel e.g. air, people and theirpractices and landforms also the weather
Environment - Class 7 - Geography (Social Studies)AnjaliKaur3
This PPT is helpful for class 7 students and for teachers looking for teaching aids. This topic is about Environment and I have explained the same in a very simple and interesting manner.
The Earth is like a big team where different parts work together to make everything work well. There are four main parts: the air around us (atmosphere), the water all around (hydrosphere), the solid ground beneath our feet (lithosphere), and all living things (biosphere). Each part has its special job.
The air around us is important because we need it to breathe and live. The water, like oceans and rivers, is a big part too. The solid ground is what we walk on, and all the living things, from plants to animals, make up the biosphere.
These parts work together to make sure everything is balanced and that life can happen. Learning how these parts work together helps us understand how our planet works and changes. It's like a big puzzle, and each piece is important!
1. Atmosphere
The Earth's atmosphere is a complex and dynamic system that surrounds the planet. It is a mixture of gases that are held in place by the Earth's gravity. The atmosphere plays a crucial role in supporting life on Earth by providing the necessary gases for respiration, regulating temperature, and protecting the planet from harmful solar radiation.
2.Biosphere (Living Things)
The biosphere refers to the part of Earth where life exists. It includes the surface of the land, the ocean, the lower atmosphere, and the upper lithosphere. The biosphere is a complex and interconnected system that sustains and supports life.
.Hydrosphere (Water)
The hydrosphere refers to the total amount of water on Earth's surface, including oceans, seas, lakes, rivers, groundwater, and even the water vapor in the atmosphere. It is a critical component of the Earth system and plays a crucial role in supporting life and influencing climate.
4.Lithosphere (Land)
The lithosphere is the outermost shell of the Earth and is composed of the Earth's crust and the uppermost part of the mantle. It is one of the Earth's four major spheres, along with the hydrosphere (water), atmosphere (air), and biosphere (living organisms). The term "lithosphere" comes from the Greek words "lithos," meaning rock, and "sphaira," meaning sphere.
Ecosystem as defined as interaction between the organisms and environment. Or living community of plants and animals in are together with non living components of environment such as soil, water and air consists the ecosystem. The word eco system coined by A.G Tensely in 1935. This ecosystem has variety of life such as flora and fauna.
Ecosystem as largest functional unit of ecology which comprises with biotic communities mutually related with their nonliving or a biotic environment.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
3. ATMOSPHERE
- Gaseous blanket of air that envelops, shields, and insulates Earth.
- Contains substances that are essential for life, including carbon, nitrogen,
oxygen and hydrogen.
- The atmosphere contains all the air in earth’s system.
4. HYDROSPHERE
- Contains all the solid, liquid, and gaseous water of the planet.
- Includes the water of earth - oceans, lakes, rivers, and glaciers.
- Water is essential for the existence and maintenance of life on earth.
5. LITHOSPHERE
- Solid part of the earth, from the core to the surface.
- Includes landforms, rocks, soils, and minerals.
7. BIOSPHERE
- Composed of all living: people, animals, and plants. Also known as the
ecosphere, is the worldwide sum of all ecosystems. It can also be termed the
zone of life on earth, a closed systems, and largely self-regulating.
- Nearly 71% of the earth’s surface is covered by bodies of water.
- Interact with each other to support life.
8. WHAT IS ENVIRONMENT?
- Environment is the surrounding in which an organization operates, including
air, water, land and natural resources.
- It is where human beings, animals, or plants lives. It is our basic life support
system. It provides the air we breathe, the water we drink, the food we eat
and the land where we live. It is a combination of natural and human made
phenomena.
9. WHAT IS AN ECOSYSTEM?
- It is a community or group of living organisms that live in and interact with
each other in a specific environment.
10. WHAT IS ECOLOGY
- It is the study of relationships between organisms and their environment.
Ecology is a branch of biology concerning interactions among organisms and
their biophysical environment that includes both biotic and abiotic
components.