1. Prostate cancer screening using PSA testing and digital rectal exams can help detect prostate cancer early when treatment may be more effective. 2. PSA levels above age-specific ranges or abnormal rectal exams should prompt further testing like TRUS biopsy to check for prostate cancer. 3. While early detection may find more cancers, not all elevated PSA levels indicate cancer and some normal PSA levels can still hide cancers, so screening has limitations.