Program for the III Swine Health Focus Group - A Global Exchange of Ideas on Gut Health in Swine, hosted at the Marriott JW Hotel in Rio de Janeiro, from 30/05/ to 01/06/2017
A holistic approach to poultry gut health - Arie Kies
Relevance of human gut research to poultry health - Jan Sikkema
Nutrigenomics and nutrigenetics - Michel Jacques Duclos
http://www.dsm.com/markets/anh/en_US/home.html
Are proteases beneficial for the environment- Kyriazakis, I. Workshop 3 presented at the Feed Proteases and enzyme seminar, Noordwijk, The Netherlands, 2014.
Probiotics- unfolding their potential in boosting poultry industryX S
Definition:
“Living microorganisms when conferred in sufficient amount on the host, will render beneficial effects on health.”(FAO/WHO)
Lactobacillus, Candida, Streptococcus, Enterococcus, Bifidobacterium, Aspergillus, and Saccharomyces spp.
History
Élie Metchnikoff (20th century)
Werner Kolath(1953)
Probiotics for poultry
Need of Probiotics?
Selection criteria
Probiotics in poultry industry
First decisive incident
Commercial vs. wild chicken
Selection criteria
Probiotic requirement in poultry (concept)
How probiotics act?
Maintain normal intestinal microflora
competitive exclusion and resistance
Change metabolism
speeding digestive enzyme activity
Perk up feed intake and digestion
Diminish bacterial enzyme activity and ammonia production
Stimulate the immune system
Evaluation of probiotics on poultry
Growth performance
Intestinal microbiota and morphology
Immune response
Meat quality/chicken caracass
Side effects(toxicity of ingredients)
Growth performance
broilers fed with two probiotic species put on more weight(Lan et al.,2003 )
weight gain significantly higher in probiotic fed birds(Kabir et al.,2004) .
inactivated probiotics have constructive actions on the production achievement (Huang et al.,2004).
Cont’d
values of giblets and dressing percentage elevated for probiotic fed broilers (Mahanjan et al.,1999)
Intestinal microbiota and morphology
Probiotics inhibited pathogens by dwelling on intestinal wall space(Kabir et al.,2005 )
Birds fed dietary B. subtilis for 28 days displayed better growth and prominent intestinal histologies. (Samanya and Yamauchi.,2002)
Chicks given Lactobacillus strains had less amount of coliforms in cecal grindings(Watkins and Kratzer.,1983 ).
Cont’d
L. salivarius 3d strain decreased the number of Clostridium perfringens and Salmonella enteritidis (Kizerwetter-Swida and Binek., 2009).
Probiotic species have an implicit action on regulation of intestinal microflora and pathogen occlusion (Higgins et al., 2007)
Immune response
Higher amount of antibody production(Kabir et al.,2005 )
Improved serum and intestinal antibodies to a foreign antigens in chickens (Haghighi et al.,2005)
Probiotics protected broilers against Eimeria acervulina infection even with a moderate dose (Dalloul et al.,2003)
Cont’d
Better local immune defenses against coccidiosis.
Splenocytes and cecal tonsil cells, STAT2 and STAT4 genes were greatly stimulated and the expression of STAT2, STAT4, IL-18, IFN-alpha, and IFN-gamma genes in cecal tonsil cells were up-regulated after treating with L. acidophilus DNA.
Additive probiotic supplements were ineffective on systemic IgG (Midilli et al.,2008 ).
A description and the results of research carried out on broiler chickens in order to explore the efficacy of phytase products on ileal digestibility of phosphorus.
The reseach results found that phytase supplementation was effective in improving the growth performance, ileal phosphorus digestibility and the bone mineralization parameters when included in the low phosphorus diet.
Visit us at: http://www.dsm.com/markets/anh/en_US/home.html
>Since the ban of antibiotic growth promoters (AGPs) in the European Union, the industry has been looking for valid alternatives to improve health, immune status and performance in animal agriculture.
>The industry focuses on developing solutions that mimic the effects of AGPs. However, the exact mode of action of the AGPs to improve poultry performance is not fully understood.
Most AGPs alternatives try to prevent the proliferation of pathogenic bacteria and to modulate indigenous bacteria to improve immune status and performance.
>As an industry, we have made limited progress in improving gut health. Maybe we need to change the approach to find the most optimal solution.
>As part of a stable ecological system, pathogens per se do not represent a threat to animal health. The dynamic nature of the gastrointestinal microflora in chickens makes maintaining the right balance in the microbial ecosystem.
>Despite a large amount of scientific work has been done on the topic, a lack of consistent improvement has been registered.
>To improve gut health more consistently, a broader approach, involving a combination of nutrition, feed technology and husbandry management needs to be taken.
>In addition, gut-health is too complex to be solved from
only one point of view. Input should be obtained from different disciplines, including food technology, human nutrition, veterinary and human medical sciences.
>DSM will start an holistic program to come to tailor made solutions to improve the gut ecosystem with the objective of reducing the use of antibiotics in the poultry industry.
A holistic approach to poultry gut health - Arie Kies
Relevance of human gut research to poultry health - Jan Sikkema
Nutrigenomics and nutrigenetics - Michel Jacques Duclos
http://www.dsm.com/markets/anh/en_US/home.html
Are proteases beneficial for the environment- Kyriazakis, I. Workshop 3 presented at the Feed Proteases and enzyme seminar, Noordwijk, The Netherlands, 2014.
Probiotics- unfolding their potential in boosting poultry industryX S
Definition:
“Living microorganisms when conferred in sufficient amount on the host, will render beneficial effects on health.”(FAO/WHO)
Lactobacillus, Candida, Streptococcus, Enterococcus, Bifidobacterium, Aspergillus, and Saccharomyces spp.
History
Élie Metchnikoff (20th century)
Werner Kolath(1953)
Probiotics for poultry
Need of Probiotics?
Selection criteria
Probiotics in poultry industry
First decisive incident
Commercial vs. wild chicken
Selection criteria
Probiotic requirement in poultry (concept)
How probiotics act?
Maintain normal intestinal microflora
competitive exclusion and resistance
Change metabolism
speeding digestive enzyme activity
Perk up feed intake and digestion
Diminish bacterial enzyme activity and ammonia production
Stimulate the immune system
Evaluation of probiotics on poultry
Growth performance
Intestinal microbiota and morphology
Immune response
Meat quality/chicken caracass
Side effects(toxicity of ingredients)
Growth performance
broilers fed with two probiotic species put on more weight(Lan et al.,2003 )
weight gain significantly higher in probiotic fed birds(Kabir et al.,2004) .
inactivated probiotics have constructive actions on the production achievement (Huang et al.,2004).
Cont’d
values of giblets and dressing percentage elevated for probiotic fed broilers (Mahanjan et al.,1999)
Intestinal microbiota and morphology
Probiotics inhibited pathogens by dwelling on intestinal wall space(Kabir et al.,2005 )
Birds fed dietary B. subtilis for 28 days displayed better growth and prominent intestinal histologies. (Samanya and Yamauchi.,2002)
Chicks given Lactobacillus strains had less amount of coliforms in cecal grindings(Watkins and Kratzer.,1983 ).
Cont’d
L. salivarius 3d strain decreased the number of Clostridium perfringens and Salmonella enteritidis (Kizerwetter-Swida and Binek., 2009).
Probiotic species have an implicit action on regulation of intestinal microflora and pathogen occlusion (Higgins et al., 2007)
Immune response
Higher amount of antibody production(Kabir et al.,2005 )
Improved serum and intestinal antibodies to a foreign antigens in chickens (Haghighi et al.,2005)
Probiotics protected broilers against Eimeria acervulina infection even with a moderate dose (Dalloul et al.,2003)
Cont’d
Better local immune defenses against coccidiosis.
Splenocytes and cecal tonsil cells, STAT2 and STAT4 genes were greatly stimulated and the expression of STAT2, STAT4, IL-18, IFN-alpha, and IFN-gamma genes in cecal tonsil cells were up-regulated after treating with L. acidophilus DNA.
Additive probiotic supplements were ineffective on systemic IgG (Midilli et al.,2008 ).
A description and the results of research carried out on broiler chickens in order to explore the efficacy of phytase products on ileal digestibility of phosphorus.
The reseach results found that phytase supplementation was effective in improving the growth performance, ileal phosphorus digestibility and the bone mineralization parameters when included in the low phosphorus diet.
Visit us at: http://www.dsm.com/markets/anh/en_US/home.html
>Since the ban of antibiotic growth promoters (AGPs) in the European Union, the industry has been looking for valid alternatives to improve health, immune status and performance in animal agriculture.
>The industry focuses on developing solutions that mimic the effects of AGPs. However, the exact mode of action of the AGPs to improve poultry performance is not fully understood.
Most AGPs alternatives try to prevent the proliferation of pathogenic bacteria and to modulate indigenous bacteria to improve immune status and performance.
>As an industry, we have made limited progress in improving gut health. Maybe we need to change the approach to find the most optimal solution.
>As part of a stable ecological system, pathogens per se do not represent a threat to animal health. The dynamic nature of the gastrointestinal microflora in chickens makes maintaining the right balance in the microbial ecosystem.
>Despite a large amount of scientific work has been done on the topic, a lack of consistent improvement has been registered.
>To improve gut health more consistently, a broader approach, involving a combination of nutrition, feed technology and husbandry management needs to be taken.
>In addition, gut-health is too complex to be solved from
only one point of view. Input should be obtained from different disciplines, including food technology, human nutrition, veterinary and human medical sciences.
>DSM will start an holistic program to come to tailor made solutions to improve the gut ecosystem with the objective of reducing the use of antibiotics in the poultry industry.
Focus on Enteric Health: The advent of a Poultry Industry without AGPsRafael Monleon
A presentation covering the topic of removal of AGPs from the poultry production.
Presented at the Korean Poultry Science Association in May 2011 by Dr. Rafael Monleon
Contact me in LinkedIn for any question: www.linkedin.com/rafaelmonleon
Robert Hutkins (University of Nebraska, USA) explored the interactions between ingested microorganisms and the gut microbiota, and the way exogenous microorganisms can change the gut environment.
Effects of Probiotics Feeding Technology on Weight Gain of Indigenous Chicken...iosrjce
IOSR Journal of Agriculture and Veterinary Science (IOSR-JAVS) is a double blind peer reviewed International Journal edited by the International Organization of Scientific Research (IOSR). The journal provides a common forum where all aspects of Agricultural and Veterinary Sciences are presented. The journal invites original papers, review articles, technical reports and short communications containing new insight into any aspect Agricultural and Veterinary Sciences that are not published or not being considered for publication elsewhere.
Numerous epidemiological studies reported that yogurt consumption may be used as a new biomarker of a healthy lifestyle. What could explain the health benefits of yogurt? At the 5th Yogurt Summit, held in Buenos Aires (Argentina) on October 18th, Dr André Marette (Laval University, Québec) presented up-to-date evidence on bioactive compounds produced during fermentation.
Ankylosing Spondylitis the gut and the bugs: an integrative approach to treat...IFSMED
Rheumatologist Dr. Alex Shikhman makes the connection between ankylosing spondylitis and the gut. Offering natural dietary supplements to help manage many of the side effects associated with the disease
Probiotics and medicinal plants in poultry nutrition: a reviewSubmissionResearchpa
The use of medicinal plants and probiotics has recently gained interest since the ban on the use of antibiotics as growth promoters by the European Union in 2006. They are new alternatives to bridge the gap between food safety and production. Medicinal plants are cheaper and loaded with several minerals, vitamins and phytochemicals such as: alkaloids, saponin, flavonoids, phenols, tannins etc. which allows them to perform multiple biological activities. Probiotics on the other hand, repopulates the gastro intestinal tracts (GIT) with beneficial bacteria which controls the action of pathogens and control their population, thereby reducing mortality and improving general performance of an animal by Akintayo - Balogun Omolere. M and Alagbe, J.O 2020. Probiotics and medicinal plants in poultry nutrition: a review. International Journal on Integrated Education. 3, 10 (Oct. 2020), 214-221. DOI:https://doi.org/10.31149/ijie.v3i10.730 https://journals.researchparks.org/index.php/IJIE/article/view/730/703 https://journals.researchparks.org/index.php/IJIE/article/view/730
Dr. Shikhman discusses reasons why you still may not feel well even after going gluten free. Covering leaky gut syndrome, yeast overgrowth, food allergies, endocrine abnormalities.
Manipulation of rumen function to augment livestock productivityUCV&AS IUB
Manipulations of rumen function that can augment livestock productivity are;
Correction of concentrate to roughage ratio
Feed bypass or escaped nutrients
Defaunation of rumen
Use of yeast as probiotics
Use of anaerobic fungi
Use of other feed additives
Focus on Enteric Health: The advent of a Poultry Industry without AGPsRafael Monleon
A presentation covering the topic of removal of AGPs from the poultry production.
Presented at the Korean Poultry Science Association in May 2011 by Dr. Rafael Monleon
Contact me in LinkedIn for any question: www.linkedin.com/rafaelmonleon
Robert Hutkins (University of Nebraska, USA) explored the interactions between ingested microorganisms and the gut microbiota, and the way exogenous microorganisms can change the gut environment.
Effects of Probiotics Feeding Technology on Weight Gain of Indigenous Chicken...iosrjce
IOSR Journal of Agriculture and Veterinary Science (IOSR-JAVS) is a double blind peer reviewed International Journal edited by the International Organization of Scientific Research (IOSR). The journal provides a common forum where all aspects of Agricultural and Veterinary Sciences are presented. The journal invites original papers, review articles, technical reports and short communications containing new insight into any aspect Agricultural and Veterinary Sciences that are not published or not being considered for publication elsewhere.
Numerous epidemiological studies reported that yogurt consumption may be used as a new biomarker of a healthy lifestyle. What could explain the health benefits of yogurt? At the 5th Yogurt Summit, held in Buenos Aires (Argentina) on October 18th, Dr André Marette (Laval University, Québec) presented up-to-date evidence on bioactive compounds produced during fermentation.
Ankylosing Spondylitis the gut and the bugs: an integrative approach to treat...IFSMED
Rheumatologist Dr. Alex Shikhman makes the connection between ankylosing spondylitis and the gut. Offering natural dietary supplements to help manage many of the side effects associated with the disease
Probiotics and medicinal plants in poultry nutrition: a reviewSubmissionResearchpa
The use of medicinal plants and probiotics has recently gained interest since the ban on the use of antibiotics as growth promoters by the European Union in 2006. They are new alternatives to bridge the gap between food safety and production. Medicinal plants are cheaper and loaded with several minerals, vitamins and phytochemicals such as: alkaloids, saponin, flavonoids, phenols, tannins etc. which allows them to perform multiple biological activities. Probiotics on the other hand, repopulates the gastro intestinal tracts (GIT) with beneficial bacteria which controls the action of pathogens and control their population, thereby reducing mortality and improving general performance of an animal by Akintayo - Balogun Omolere. M and Alagbe, J.O 2020. Probiotics and medicinal plants in poultry nutrition: a review. International Journal on Integrated Education. 3, 10 (Oct. 2020), 214-221. DOI:https://doi.org/10.31149/ijie.v3i10.730 https://journals.researchparks.org/index.php/IJIE/article/view/730/703 https://journals.researchparks.org/index.php/IJIE/article/view/730
Dr. Shikhman discusses reasons why you still may not feel well even after going gluten free. Covering leaky gut syndrome, yeast overgrowth, food allergies, endocrine abnormalities.
Manipulation of rumen function to augment livestock productivityUCV&AS IUB
Manipulations of rumen function that can augment livestock productivity are;
Correction of concentrate to roughage ratio
Feed bypass or escaped nutrients
Defaunation of rumen
Use of yeast as probiotics
Use of anaerobic fungi
Use of other feed additives
Indian Nutritional Medical Association (INMA) began in 2004 by Dr.A. Sreekumar MBBS,DLO,Senior ENT Surgeon and Nutritional Medicine expert, FACNEM,FINEM
www.4innmc.com
Presentation during the IV International Symphosium on Nutritional requirements of Poultry and Swine on March 29th - by Gilberto Litta DSM Animal Nutrition.
Main Message of the presentation is the importance of vitamin in Poultry Nutrition as well as the multiple benefits achievable.
Introduction
The mineral content in animal body is 2-5%.
• Most abundant minerals in
body:
– 36-39% Ca (bone ash)
– 17-19% P (bone ash)
Conclusion
STTD Ca requirements for 11 to 25 kg pigs:
– ADG is between 0.36 and 0.56%, G:F is 0.43%
– Bone ash, bone Ca, and bone P is between 0.48 and 0.56%
– Ca retention and P retention is between 0.48 and 0.52%
Recent research on vitamin requirement of modern swine breeds under current husbandry conditions is limited; tabular recommendations may underestimate the actual needs of growing pigs and breeding sows.
Clinical / subclinical vitamin deficiency can still occur within industrial swine production:
optimum vitamin supplementation prevents from deficiency and
exploits the genetic performance potential of swine.
Superior dietary supplementation levels of certain vitamins do provide additional value, such as improved stress and disease resistance, adequate welfare or better product quality.
Feeding strategy
• Animal Requirements change with criteria: need to take into account various parameters to optimise performance
- need to take into account complexity due to variability of response and interaction,
no single dose response
- Availability of new tools to integrate complexity (model for dietary formulaƟon)
• Feed recommendation in sustainable system should integrate three objectives: production performance, environment and welfare
Product quality
• Limited influence on lipid fraction
• Effects on oxidation remains controversial
- anƟoxidant vs pro-oxidant
- interacƟons between level and duration of trace elements dietary level, issue, slaughtering conditions, product packaging and transformation, cooking.
• Good potential of product enrichment in trace mineral but limitation due to Regulation in
animal and human feeding and due to toxicity level for animals
General conclusions
- Current methods used by the industry to evaluate protein quality are not capable of detecting existing differences among SBM
- The composition and the protein quality of SBM vary with the origin of the bean
- Different matrixes should be used for SBM of different origins, NIR technology might help
- Proteases might improve the uniformity and nutritive value of SBM batches
Conclusions
• Each additive affects microflora in a different manner
• Succesful and Sustentable Additives should contribute to mantain microflora diversity
• Some additives may also affect the host directly, not only the microbial communities
• Effects at host level should be understood and used to improve holistic efficiency
Conclusions of the research:
Feeding 25OHD3 in place of the majority of dietary D3 improved broiler chicken vitamin D status and resulted in
a satellite cell-mediated muscle hypertrophy response in breast (PM), but not thigh (BF) muscles (Hutton et al.,
2013)
The differential response in functionally different muscles as well as the cell signaling mechanisms by which skeletal
muscle satellite cells respond to improved vitamin D status resulting from dietary Hy·D supplementation will
require further investigation.
Phytate is a natural dietary content and constitutes 0.4–6.4% (w/w) of most cereals and legumes (Eeckhout and Deaepe, 1994). It is poorly digestible for monogastric animals due to
a lack of effective endogenous phytase (Bitar and Reinhold, 1972). Phytate acts as an antinutritional factor, exerting its effects via a reduction in the solubility, and availability of
phosphorus (P), and to a lesser extent, Ca, Zn, Fe (Nävert et al., 1985; Hallberg et al., 1987; Hurrell et al., 2003). It was also reported that phytate could decrease the utilization of protein,
amino acids and starch. It has been suggested that phytate may bind with starch either directly, via hydrogen bonds, or indirectly, via proteins associated with starch (Thompson,
1988; Rickard and Thompson, 1997). Phytate is also known to inhibit a number of digestive enzymes such as pepsin, alpha-amylase (Deshpande and Cheryan, 1984) and increase mucin
secretion, excretion of endogenous minerals and amino acids in broiler chickens (Liu et al., 2008). Another issue is higher cost of dietary inorganic P which has been increased remarkably in last decade because of shortened phospate sources. Poultry industry has still been growing and reached huge mass production and contribution to environmental pollution has been heightened concerns because of the poor utilization of phytate phosphorus by poultry.
Protein/amino acids are among the most expensive nutrients to deliver in poultry nutrition
The digestibility of protein in poultry is typically incomplete by the terminal ileum
Undigested protein that leaves the ileum is from both exogenous (diet) and endogenous (bird) sources
Understanding the digestion of dietary proteins and the recovery of endogenous proteins is important and can provide a basis for the use of exogenous proteases
Research has demonstrated that phytase is the only enzyme that is able to initiate
the release of phosphorus (P) from the phytate molecule, making it available for
absorption and utilization (Selle and Ravindran, 2007). The industrial demand for
phytases with greater potency in intestinal phytate hydrolysis and better heat
stability continues to stimulate the search for new enzyme sources. Enzyme
preparations with phytases derived from A. ficuum, Peniophora lycii and E. coli are
available commercially. More recently, new microbial 6-phytases produced by
synthetic genes, mimicking a gene from C. braakii or isolated from Buttiauxella,
were introduced into the market.
Phytase efficiency to increase phosphorus utilization in
poultry has been proven for decades. In addition,
phytase was demonstrated to improve growth
performance, meat breast weight, amino acids
digestibility and plasma myo-inositol concentration.
The objective of this work was to investigate potential
interactions between phytase supplementation, growth
performance and host gene expression to identify
potential associated biomarkers.
Knowledge of amino acid (AA) digestibility of feed ingredients is necessary to feed broilers with
properly balanced compound diets. For this reason, more attention has recently been given to the
determination of AA digestibility of ingredients, recognizing that it may vary greatly depending
upon the feed ingredient. The effects of the inclusion of a mono-component serine protease
(Ronozyme® ProAct) on standardized ileal amino acid digestibility (SIAAD) of diets containing wheat
by-products (wheat DDGS (WDDGS) and wheat middlings (WM)) were evaluated in broilers.
- Improvement of SIAAD in the presence of protease is not the same for all AA and varies from one ingredient to another one. The effects of added protease are dependent on feed composition and on intrinsic digestibility of AA (COWIESON and ROOS (2014)).
- Factors such as type and quality of the ingredients, industrial processing and the presence of anti-nutritional substances such as tannins, phytates, trypsin inhibitors in plant species modulate the digestibility in poultry feed and thus the effectiveness of exogenous protease.
-The physiological state of animals (growth or maintenance), feed consumption or the nutritional feed quality could also influence the digestibility values.
Hatchability is certainly a key performance and profitability
parameter for chick producers. Storing hatching eggs is a
current necessary practice and this can damage hatchability
results. Canthaxanthin, as an antioxidant, is particularly
effective for supporting hatchability. The vitelline membrane
strength (VMS) is very important to the early embryo survival.
The vitelline membrane protects the embryo (pH 6) from the
high pH of the albumen (pH 9.4) and therefore has to be
strong enough. The embryo progressively gets surrounded
by the yolk sac and is totally protected in the yolk sac between
day 3 and 4 of incubation.
Hatchability is certainly a key performance and profitability parameter for chick producers. Storing hatching eggs is a current practice and this can damage hatchability results. Canthaxanthin, as an antioxidant, is particularly effective for supporting hatchability. The vitelline membrane strength (VMS) is very important to the early embryo survival that can-thaxanthin can promote it. The experiment involved a flock of 3,800 breeders (males and females) separated into two adjacent blocks. Feeding experiment started at 18 weeks of age with a control diet as 3000 IU/kg Vitamin D3 and no Carophyll® supplementation and experimental diet as 1,600 IU/kg vitamin D3, 37.5 μg/kg 25-hydroxy-vitamin D3 (HyD®) & 6 mg/kg canthaxanthin (Carophyll® Red 10%). Vitamin D3 or 25-hydroxy-vitamin D3 were not expected to have any influence on the VMS. Eggs were collected at 40/45 weeks and stored 7 days. The VMS was evaluated using a com-pression machine. Stiffness and breaking strength were significantly increased with the supplementation of canthaxan-thin. Thanks to the unique capabilities of high deposition rate in the yolk and singlet oxygen quenching capabilities, canthaxanthin from Carophyll® can improve the VMS in complement to Vitamin E and we hypothesized that it contrib-utes to explain its influence on early embryo viability and hatchability in breeder performance.
We investigated the effects of protease (Ronozyme ProAct, PRO) supplementation on the AID of 3 cereals in the presence or not of a multi-enzyme complex with β-glucanase and β-xylanase activity (GLU+XYL). The AID of most of AA was higher for corn and wheat than for barley. The inclusion of GLU+XYL increased the AID of DM, CP and of all the AA, except Met and Lys. The inclusion of PRO increased the AID of Gly and tended to increase that of most of the other AA. The combination of both enzymes did not improve further AA digestibility any.
Variation in trypsin inhibitor activity (TIA) and protein solubility within commercial soybean meals (SBM) is believed to affect animal performance. The objective of this research was to investigate the proteolytic effect of purified pancreatic trypsin/chymotrypsin and a purified protease from Nocardiopsis prasina on 9 commercial SBM samples varying in chemical composition, TIA and protein solubility characteristics. SBM was incubated with or without protease (pH 7, 3 hours, 40°C) and the supernatants were analyzed by SDS-page and for level of free soluble amino ends using the o-phthal-dialdehyde method. SDS-page analysis showed differences in the amount and composition of the soluble protein fraction of the SBM. The proteolytic efficiency of the lower dosages of pancreatic protease varied extensively between SBM batches whereas at the highest dose the efficiency was comparable for all SBM. The difference could not be explained by differences in protein solubility and TIA values as isolated variables, but the data strongly suggest that the hydrolysis of soya protein by pancreatic proteases depends on the commercial batch of SBM used. Incubation with N. prasina protease showed similar response for the different SBM, the main difference being a somewhat lower effect at high protease dose for one of the SBM batches, which might be in part explained by its distinct lower protein solubility
Viscosity reduction by three feed enzymes was measured in a high throughput pressure sensing system using commercial dosages on purified polysaccharides (arabinoxylan and ß-glucan). Fluorescence and antibody microscopy techniques were also used to visualize effects on the solubilisation of endosperm cell walls of wheat and barley.
Viscosity data clearly demonstrated depolymerisation of mixed-linked ß-glucans by the two multicomponent enzymes. The two multicomponent enzymes also reduced the viscosity of the arabinoxylan solution, while the monocomponent xylanase most effectively depolymerised the arabinoxylan. Microscopy data revealed that the multicomponent enzyme chosen for the studies could solubilize barley cell walls by targeting both the ß-glucan strutures as well as the arabinoxylans. The xylanase could effectively solubilise barley cell walls by merely attacking the arabinoxylans.
Exogenous carbohydrases such as xylanases, amylases, and glucanases have been reported to improve energy utilization and performance of broiler chickens (Olukosi et al., 2008; Vieira et al., 2015). These enzymes may improve the access of endogenous enzymes to cell contents due to hydrolysis of cell wall arabinoxylans (Kocher et al., 2003) as well as to augment endogenous amylase in young birds (Gracia et al., 2003). Decreases in endogenous amino acid losses may also contribute to the beneficial effects of amylases (Jiang et al., 2008).
Introduction to AI for Nonprofits with Tapp NetworkTechSoup
Dive into the world of AI! Experts Jon Hill and Tareq Monaur will guide you through AI's role in enhancing nonprofit websites and basic marketing strategies, making it easy to understand and apply.
Model Attribute Check Company Auto PropertyCeline George
In Odoo, the multi-company feature allows you to manage multiple companies within a single Odoo database instance. Each company can have its own configurations while still sharing common resources such as products, customers, and suppliers.
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasn’t one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
Operation “Blue Star” is the only event in the history of Independent India where the state went into war with its own people. Even after about 40 years it is not clear if it was culmination of states anger over people of the region, a political game of power or start of dictatorial chapter in the democratic setup.
The people of Punjab felt alienated from main stream due to denial of their just demands during a long democratic struggle since independence. As it happen all over the word, it led to militant struggle with great loss of lives of military, police and civilian personnel. Killing of Indira Gandhi and massacre of innocent Sikhs in Delhi and other India cities was also associated with this movement.
Acetabularia Information For Class 9 .docxvaibhavrinwa19
Acetabularia acetabulum is a single-celled green alga that in its vegetative state is morphologically differentiated into a basal rhizoid and an axially elongated stalk, which bears whorls of branching hairs. The single diploid nucleus resides in the rhizoid.
Francesca Gottschalk - How can education support child empowerment.pptxEduSkills OECD
Francesca Gottschalk from the OECD’s Centre for Educational Research and Innovation presents at the Ask an Expert Webinar: How can education support child empowerment?
How to Make a Field invisible in Odoo 17Celine George
It is possible to hide or invisible some fields in odoo. Commonly using “invisible” attribute in the field definition to invisible the fields. This slide will show how to make a field invisible in odoo 17.
This slide is special for master students (MIBS & MIFB) in UUM. Also useful for readers who are interested in the topic of contemporary Islamic banking.
Normal Labour/ Stages of Labour/ Mechanism of LabourWasim Ak
Normal labor is also termed spontaneous labor, defined as the natural physiological process through which the fetus, placenta, and membranes are expelled from the uterus through the birth canal at term (37 to 42 weeks
June 3, 2024 Anti-Semitism Letter Sent to MIT President Kornbluth and MIT Cor...Levi Shapiro
Letter from the Congress of the United States regarding Anti-Semitism sent June 3rd to MIT President Sally Kornbluth, MIT Corp Chair, Mark Gorenberg
Dear Dr. Kornbluth and Mr. Gorenberg,
The US House of Representatives is deeply concerned by ongoing and pervasive acts of antisemitic
harassment and intimidation at the Massachusetts Institute of Technology (MIT). Failing to act decisively to ensure a safe learning environment for all students would be a grave dereliction of your responsibilities as President of MIT and Chair of the MIT Corporation.
This Congress will not stand idly by and allow an environment hostile to Jewish students to persist. The House believes that your institution is in violation of Title VI of the Civil Rights Act, and the inability or
unwillingness to rectify this violation through action requires accountability.
Postsecondary education is a unique opportunity for students to learn and have their ideas and beliefs challenged. However, universities receiving hundreds of millions of federal funds annually have denied
students that opportunity and have been hijacked to become venues for the promotion of terrorism, antisemitic harassment and intimidation, unlawful encampments, and in some cases, assaults and riots.
The House of Representatives will not countenance the use of federal funds to indoctrinate students into hateful, antisemitic, anti-American supporters of terrorism. Investigations into campus antisemitism by the Committee on Education and the Workforce and the Committee on Ways and Means have been expanded into a Congress-wide probe across all relevant jurisdictions to address this national crisis. The undersigned Committees will conduct oversight into the use of federal funds at MIT and its learning environment under authorities granted to each Committee.
• The Committee on Education and the Workforce has been investigating your institution since December 7, 2023. The Committee has broad jurisdiction over postsecondary education, including its compliance with Title VI of the Civil Rights Act, campus safety concerns over disruptions to the learning environment, and the awarding of federal student aid under the Higher Education Act.
• The Committee on Oversight and Accountability is investigating the sources of funding and other support flowing to groups espousing pro-Hamas propaganda and engaged in antisemitic harassment and intimidation of students. The Committee on Oversight and Accountability is the principal oversight committee of the US House of Representatives and has broad authority to investigate “any matter” at “any time” under House Rule X.
• The Committee on Ways and Means has been investigating several universities since November 15, 2023, when the Committee held a hearing entitled From Ivory Towers to Dark Corners: Investigating the Nexus Between Antisemitism, Tax-Exempt Universities, and Terror Financing. The Committee followed the hearing with letters to those institutions on January 10, 202
June 3, 2024 Anti-Semitism Letter Sent to MIT President Kornbluth and MIT Cor...
DSM Swine Health Focus Group 2017 Program
1. HEALTH • NUTRITION • MATERIALS
Swine Health Focus Group
3rd
edition
A Global Exchange of Ideas on Gut Health in Swine
Marriott JW Hotel
Avenida Atlantica, 2600, Copacabana, Rio de Janeiro, Brazil
May 30th
- June 1st
, 2017
2. Aim of the Meeting
1. Create a panel of experts with experience in the use of Eubiotics
such as organic acids, essential oils and probiotics
2. Exchange ideas, experience, knowledge, questions on the issues of
gut health and the use of Eubiotics in swine production
3. Exchange on the future needs as seen by the industry and the
academic world and push initiatives that support the development
of the feed industry
Swine Industry Hot Topics
• Gut health
• ABF production
• Antibotic use
• Post-weaning diarrhea
• Feed cost
• Sustainability
• Antimicrobial resistance
• Uniformity
• Salmonella control
• Sow lifetime productivity
• Cost-effective alternatives
to AGP, ZnO, Cu
• Enteric disorders
• Feeding the modern sow
• Eubiotics
• Feed efficiency
• Pig performance
• Piglet vitality
3. May 30th
May 31st
June 1st
June 2nd
Morning
Arrivals
Swine Health focus
group meeting Day 1
8:30 AM - 12:30 PM
“Gut health in swine:
definition and
monitoring”
“Eubiotic DSM vision”
Lectures & QA session
Swine Health focus
group meeting Day 2
8:30 AM - 12:30 PM
“Global antibiotic
reduction context and
gut health strategies”
Lectures & QA session
7:00 AM - 11:00 AM
Hotel Check-out &
Sights-Seeing Part 2
Lunch Hotel Hotel Hotel
Afternoon
1:45 PM - 5:30 PM
Group discussion &
Guests’ presentations
1:45 PM - 5:00 PM
Group discussion &
Guests’ presentations
Individual departures
Evening
7:00 PM
Welcoming Cocktail
Dinner
7:00 PM
Dinner in Rio de Janeiro
6:00 PM
Sights-Seeing Part 1
9:00 PM
Dinner in Rio de Janeiro
Agenda
General program
4. Time Morning Session Agenda
8:30 AM - 12:30 PM
Welcome Augusto Adami VP ANH LATAM, DSM
Meeting Introduction Antoine Meuter Global Eubiotics Manager, DSM
Improving Gut Health through Nutrition Dr Jean-Paul Lallès Director of Research, INRA - France
Healthy gut & related biomarkers -
The Scientific view.
Dr Pietro Celi Senior Scientist, DSM
Gut health in pigs and how to evaluate it
on the farm? The Veterinarian view
Dr Juan José
Maqueda
Swine Veterinarian Consultant,
Mexico
DSM vision on Eubiotics Ole Lund Svendsen Global Eubiotics Manager, DSM
12:30 PM - 1:45 PM Lunch Break – Marriott Hotel
Time Afternoon Session Agenda
1:45 PM - 5:30 PM
Group discussion on morning’s topics
Adsos Passos
& Antoine Meuter
(Facilitators)
DSM LATAM
DSM GLOBALGuests’ presentations
Wrap-up Day 1
7:00 PM - 11:00 PM Dinner in Rio de Janeiro
Agenda
Swine Health Focus group meeting Day 1
5. Time Morning Session Agenda
8:30 AM - 12:30 PM
Aspects of AGP free production in swine -
The Brazilian experience
Dr Geraldo
Alberton
Associate Professor,
Universidade Federal do Paraná - Brazil
Alternative to feed with antibiotics, Zinc
and copper, the Danish case
Dr Niels Jørgen
Kjeldsen
Chief Consultant Pig Industry,
Pig Research Center - Seges
Healthy Sow, Healthy piglets
Dr José-Antonio
Cuaron
Centro Nacional de Investigación
Disciplinaria en Fisiología Animal,
INIFAP
How to reach maximum weaned piglet
growth in a healthy way?
René
Bonekamp
Regional Swine Specialist EMEA, DSM
12:30 PM - 1:45 PM Lunch Break – Marriott Hotel
Time Afternoon Session Agenda
1:45 PM - 5:00 PM
Group discussion on morning’s topics Adsos Passos
& Antoine
Meuter
(Facilitators)
DSM LATAM
DSM GLOBALGuests’ presentations
Wrap-up Day 2 & meeting closure
6:00 PM - 11:30 PM Visit of the Corcovado by night & Dinner in Rio de Janeiro
Agenda
Swine Health Focus group meeting Day 2
6. Dr Jean-Paul Lallès
INRA
Research Director of INRA
Rennes, France
Dr Juan José Maqueda
Independant consultant
Swine production, Mexico
Swine Veterinarian
Dr Niels Jørgen Kjeldsen
Danish Pig Research
Center/Seges
Chief consultant - Pig Industry
Dr Geraldo Alberton
Universidade Federal do
Paraná – Brazil
Associate Professor
Dr José-Antonio Cuaron
INIFAP, Mexico
Director, National Research
Center for Animal Physiology
Speakers
7. Date Time Activity
Tuesday, Evening 7:00 PM
Welcoming Cocktail & Dinner
Marriott Hotel – Rooftop
Wednesday, Evening 7:30 PM Dinner – Restaurant in Rio de Janeiro
Thursday, Late afternoon 6:00 PM Visit of the Corcovado by night
Thursday, Evening 9:00 PM Dinner – Restaurant in Rio de Janeiro
Friday, Morning 7:00 AM Visit of Sugarloaf Mountain
Meeting Venue and Hotel
http://www.marriott.com/hotels/travel/riomc-jw-marriott-hotel-rio-de-janeiro/
Social Event Program
8. Contact details of DSM event organizers if you need assistance in Rio de Janeiro :
Antoine Meuter: +41 079 572 87 50, antoine.meuter@dsm.com
Adsos Passos: +55 196 443 79 49, adsos.passos@dsm.com