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National Institute
of Antimicrobial
Resistance
Research &
Education
BASED AT
National Institute of Antimicrobial Resistance Research & Education
“The thoughtless person playing
with penicillin treatment is morally
responsible for the death of the man
who succumbs to infection with the
penicillin-resistant organism.”
National Institute of Antimicrobial Resistance Research & Education
REGIONAL AMR CONSORTIUM
• In place at ISU since 2015
• Consortium members include: UNL, U of I, Mayo, USDA, Commodity Stakeholders
• Generates evidence-based rationales for antibiotic stewardship
• Contributes to improvements in animal, health, people, and the environment
• Facilitates economically and socially sound policy development for the Midwest
National Institute of Antimicrobial Resistance Research & Education
AMR CONSORTIUM INVOLVEMENT
National Institute of Antimicrobial Resistance Research & Education
HOW DID NIAMRRE
COME ABOUT?
• AAVMC and APLU task force
evaluated what actions would have
the most potential to be
transformative
• Identified formation of National
Institute of Antimicrobial Resistance
Research & Education as priority
National Institute of Antimicrobial Resistance Research & Education
MISSION
NIAMRRE will provide local, national, and international leadership in combating antimicrobial
resistance; generating evidence-based solutions for antimicrobial stewardship; contributing
to improvements in the health of animals, humans, and the environment (One Health); and
facilitating economically and socially sound policy development and implementation.
National Institute of Antimicrobial Resistance Research & Education
VISION
NIAMRRE will drive collaborative
and integrative research, education,
and engagement to solve AMR
challenges and benefit society
using a One-Health approach.
National Institute of Antimicrobial Resistance Research & Education
NIAMRRE STRUCTURE
National Institute of Antimicrobial Resistance Research & Education
ABOUT NIAMRRE
INCLUSIVE INSTITUTE
SHARED SOLUTIONS
ACCESSIBLE
DATA
INCLUSIVE INSTITUTE
SHARED SOLUTIONS
ACCESSIBLE DATA
PROVEN EXPERTISE
The NIAMRRE brand is independent of the host and member
institutions; a separate, inclusive entity. Within our institute, we
intend to represent academia, commodity, and industry in our efforts.
PROVEN
EXPERTISE
NIAMRRE was competitively selected by two national organizations
(APLU & AAVMC) to collaboratively lead local, national, and
international antimicrobial resistance and stewardship efforts.
Stakeholder engagement is valued and encouraged. Cross-
disciplinary participation from stakeholders will help bridge
resource and knowledge gaps and allow for stronger collaboration.
Through our efforts we’ll strive to make antimicrobial resistance
and stewardship project data accessible, while maintaining
intellectual property and appropriately validating results.
National Institute of Antimicrobial Resistance Research & Education
CURRENT THEMES
PRECISION
AGRICULTURE
IMPROVED
DESIGN
COMPREHENSIVE
MONITORING
STEWARDSHIP
PROMOTION
Reducing antimicrobial use by adapting precision
agriculture approaches to animal agriculture
management.
Improving clinical design making related to
antibiotics by development of innovative, rapid and
clinically translatable diagnostic testing platforms.
Development of systems-approaches for
comprehensive monitoring and modeling of
antimicrobial resistance progression at all stakeholder
levels from farm to environment and public health.
Promoting antimicrobial stewardship through
integrated public outreach, extension and clinical
training of health professionals.
National Institute of Antimicrobial Resistance Research & Education
Mike Boehm,
University of Nebraska
Vice Chancellor, Institute
of Agriculture and Natural
Resources
NIAMRRE INTERIM ADVISORY COMMITTEE
Bernadette Dunham,
George Washington
University
Former Director of FDA
Center for Veterinary Medicine
Lonnie King,
Co-Chair PAC-CARB
Former Dean, Ohio State
University College of
Veterinary Medicine
Robin Patel,
Mayo Clinic
Incoming President,
American Society for
Microbiology (ASM)
Sarah Nusser,
Iowa State University
Vice President for
Research
Paul Plummer,
Iowa State University
Executive Director,
National Institute of
Antimicrobial
Resistance Research
& EducationCathie Woteki,
Iowa State University
Former USDA
Undersecretary and
Chief Scientist
National Institute of Antimicrobial Resistance Research & Education
NIAMRRE
NEXT STEPS
• Stakeholder engagement to drive membership
and agenda development
• Identify and build sustainable funding sources
to assure longevity
National Institute of Antimicrobial Resistance Research & Education
GOVERNMENTAL AFFAIRS
• Coordinating twice monthly govt. affairs
phone calls with APLU, AAVMC, and
partners
• At present, pursuing appropriations “ask” in
line and consistent with S-FAR
• As opportunity arises we would like to
advocate for potential multi-agency joint
funding for coordinating centers like ours
National Institute of Antimicrobial Resistance Research & Education
CONTACT US
Paul Plummer, Executive Director
pplummer@nationalAMRinstitute.org
515.294.3352
2901 S Loop Drive, Suite 3300
Iowa State Research Park
Ames, IA 50010
www.nationalAMRinstitute.org

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Dr. Paul Plummer - National Institute Of Antimicrobial Resistance Research & Education

  • 2. National Institute of Antimicrobial Resistance Research & Education “The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.”
  • 3. National Institute of Antimicrobial Resistance Research & Education REGIONAL AMR CONSORTIUM • In place at ISU since 2015 • Consortium members include: UNL, U of I, Mayo, USDA, Commodity Stakeholders • Generates evidence-based rationales for antibiotic stewardship • Contributes to improvements in animal, health, people, and the environment • Facilitates economically and socially sound policy development for the Midwest
  • 4. National Institute of Antimicrobial Resistance Research & Education AMR CONSORTIUM INVOLVEMENT
  • 5. National Institute of Antimicrobial Resistance Research & Education HOW DID NIAMRRE COME ABOUT? • AAVMC and APLU task force evaluated what actions would have the most potential to be transformative • Identified formation of National Institute of Antimicrobial Resistance Research & Education as priority
  • 6. National Institute of Antimicrobial Resistance Research & Education MISSION NIAMRRE will provide local, national, and international leadership in combating antimicrobial resistance; generating evidence-based solutions for antimicrobial stewardship; contributing to improvements in the health of animals, humans, and the environment (One Health); and facilitating economically and socially sound policy development and implementation.
  • 7. National Institute of Antimicrobial Resistance Research & Education VISION NIAMRRE will drive collaborative and integrative research, education, and engagement to solve AMR challenges and benefit society using a One-Health approach.
  • 8. National Institute of Antimicrobial Resistance Research & Education NIAMRRE STRUCTURE
  • 9. National Institute of Antimicrobial Resistance Research & Education ABOUT NIAMRRE INCLUSIVE INSTITUTE SHARED SOLUTIONS ACCESSIBLE DATA INCLUSIVE INSTITUTE SHARED SOLUTIONS ACCESSIBLE DATA PROVEN EXPERTISE The NIAMRRE brand is independent of the host and member institutions; a separate, inclusive entity. Within our institute, we intend to represent academia, commodity, and industry in our efforts. PROVEN EXPERTISE NIAMRRE was competitively selected by two national organizations (APLU & AAVMC) to collaboratively lead local, national, and international antimicrobial resistance and stewardship efforts. Stakeholder engagement is valued and encouraged. Cross- disciplinary participation from stakeholders will help bridge resource and knowledge gaps and allow for stronger collaboration. Through our efforts we’ll strive to make antimicrobial resistance and stewardship project data accessible, while maintaining intellectual property and appropriately validating results.
  • 10. National Institute of Antimicrobial Resistance Research & Education CURRENT THEMES PRECISION AGRICULTURE IMPROVED DESIGN COMPREHENSIVE MONITORING STEWARDSHIP PROMOTION Reducing antimicrobial use by adapting precision agriculture approaches to animal agriculture management. Improving clinical design making related to antibiotics by development of innovative, rapid and clinically translatable diagnostic testing platforms. Development of systems-approaches for comprehensive monitoring and modeling of antimicrobial resistance progression at all stakeholder levels from farm to environment and public health. Promoting antimicrobial stewardship through integrated public outreach, extension and clinical training of health professionals.
  • 11. National Institute of Antimicrobial Resistance Research & Education Mike Boehm, University of Nebraska Vice Chancellor, Institute of Agriculture and Natural Resources NIAMRRE INTERIM ADVISORY COMMITTEE Bernadette Dunham, George Washington University Former Director of FDA Center for Veterinary Medicine Lonnie King, Co-Chair PAC-CARB Former Dean, Ohio State University College of Veterinary Medicine Robin Patel, Mayo Clinic Incoming President, American Society for Microbiology (ASM) Sarah Nusser, Iowa State University Vice President for Research Paul Plummer, Iowa State University Executive Director, National Institute of Antimicrobial Resistance Research & EducationCathie Woteki, Iowa State University Former USDA Undersecretary and Chief Scientist
  • 12. National Institute of Antimicrobial Resistance Research & Education NIAMRRE NEXT STEPS • Stakeholder engagement to drive membership and agenda development • Identify and build sustainable funding sources to assure longevity
  • 13. National Institute of Antimicrobial Resistance Research & Education GOVERNMENTAL AFFAIRS • Coordinating twice monthly govt. affairs phone calls with APLU, AAVMC, and partners • At present, pursuing appropriations “ask” in line and consistent with S-FAR • As opportunity arises we would like to advocate for potential multi-agency joint funding for coordinating centers like ours
  • 14. National Institute of Antimicrobial Resistance Research & Education CONTACT US Paul Plummer, Executive Director pplummer@nationalAMRinstitute.org 515.294.3352 2901 S Loop Drive, Suite 3300 Iowa State Research Park Ames, IA 50010 www.nationalAMRinstitute.org

Editor's Notes

  1. By 2050, 10 million lives a year and a cumulative 100 trillion USD of economic output are at risk due to the rise of drug-resistant infections if we do not find proactive solutions now to slow down the rise of drug resistance. The Review on Antimicrobial Resistance, Commissioned by UK Prime Minister and completed in late 2016
  2. In this slide we will discuss some brief comments regarding the fact that even after the discovery of the new antibiotic (penicillan) Fleming predicted and demonstrated the development of resistance before the drug was even released.
  3. In this slide the point is that AMR results in loss of efficacy regardless of host species. Therefore, as livestock producers we need to be equally concerned about the loss of efficacy of our antibiotics for treatment of disease in livestock. One example here would be the complete loss of tetracycline for control of small ruminant abortions in livestock.
  4. -Interim Executive Committee formation to help shape and direct governance development – In process -Stakeholder engagement to drive membership and agenda development -Identify and build sustainable funding sources to assure longevity