Dominique L. Monnet Director del programa ARHAI (Antimicrobial Resistance and Healthcare-Associated Infections) del Centro Europeo para la Prevención y el Control de las Enfermedades (ECDC).
El martes 5 de junio del 2018 organizamos una Jornada en la Fundación Ramón Areces, en la cual se habló sobre el consumo de antibióticos y transmisión de resistencia entre humanos y animales.
Jordi Torren - Coordinador del proyecto ESVAC. Agencia Europea de Medicamento...Fundación Ramón Areces
El martes 5 de junio del 2018 organizamos una Jornada en la Fundación Ramón Areces, en la cual se habló sobre el consumo de antibióticos y transmisión de resistencia entre humanos y animales.
Partners of the Program Against African Trypanosomosis: Research institutions...ILRI
Presentation by Bernard Bett at an ad hoc meeting of partners of the Program Against African Trypanosomosis on the progressive control pathway for African animal trypanosomosis, Rome, Italy, 11–13 December 2017.
Presentation from the 3rd Joint Meeting of the Antimicrobial Resistance and Healthcare-Associated Infections (ARHAI) Networks, organised by the European Centre of Disease Prevention and Control - Stockholm, 11-13 February 2015
Food for Thought - on the Economics of Animal Testingv2zq
Food for Thought - on the Economics of Animal Testing - Resources for Healthy Children www.scribd.com/doc/254613619 - For more information, Please see Organic Edible Schoolyards & Gardening with Children www.scribd.com/doc/254613963 - Gardening with Volcanic Rock Dust www.scribd.com/doc/254613846 - Double Food Production from your School Garden with Organic Tech www.scribd.com/doc/254613765 - Free School Gardening Art Posters www.scribd.com/doc/254613694 - Increase Food Production with Companion Planting in your School Garden www.scribd.com/doc/254609890 - Healthy Foods Dramatically Improves Student Academic Success www.scribd.com/doc/254613619 - City Chickens for your Organic School Garden www.scribd.com/doc/254613553 - Huerto Ecológico, Tecnologías Sostenibles, Agricultura Organica www.scribd.com/doc/254613494 - Simple Square Foot Gardening for Schools - Teacher Guide www.scribd.com/doc/254613410 - Free Organic Gardening Publications www.scribd.com/doc/254609890 ~
Presentation from the 3rd Joint Meeting of the Antimicrobial Resistance and Healthcare-Associated Infections (ARHAI) Networks, organised by the European Centre of Disease Prevention and Control - Stockholm, 11-13 February 2015
Roundtable of aflatoxin experts on
“Building a multi-stakeholder approach to mitigate aflatoxin contamination of food and feed”
Brussels, Monday 25th January 2016
Jordi Torren - Coordinador del proyecto ESVAC. Agencia Europea de Medicamento...Fundación Ramón Areces
El martes 5 de junio del 2018 organizamos una Jornada en la Fundación Ramón Areces, en la cual se habló sobre el consumo de antibióticos y transmisión de resistencia entre humanos y animales.
Partners of the Program Against African Trypanosomosis: Research institutions...ILRI
Presentation by Bernard Bett at an ad hoc meeting of partners of the Program Against African Trypanosomosis on the progressive control pathway for African animal trypanosomosis, Rome, Italy, 11–13 December 2017.
Presentation from the 3rd Joint Meeting of the Antimicrobial Resistance and Healthcare-Associated Infections (ARHAI) Networks, organised by the European Centre of Disease Prevention and Control - Stockholm, 11-13 February 2015
Food for Thought - on the Economics of Animal Testingv2zq
Food for Thought - on the Economics of Animal Testing - Resources for Healthy Children www.scribd.com/doc/254613619 - For more information, Please see Organic Edible Schoolyards & Gardening with Children www.scribd.com/doc/254613963 - Gardening with Volcanic Rock Dust www.scribd.com/doc/254613846 - Double Food Production from your School Garden with Organic Tech www.scribd.com/doc/254613765 - Free School Gardening Art Posters www.scribd.com/doc/254613694 - Increase Food Production with Companion Planting in your School Garden www.scribd.com/doc/254609890 - Healthy Foods Dramatically Improves Student Academic Success www.scribd.com/doc/254613619 - City Chickens for your Organic School Garden www.scribd.com/doc/254613553 - Huerto Ecológico, Tecnologías Sostenibles, Agricultura Organica www.scribd.com/doc/254613494 - Simple Square Foot Gardening for Schools - Teacher Guide www.scribd.com/doc/254613410 - Free Organic Gardening Publications www.scribd.com/doc/254609890 ~
Presentation from the 3rd Joint Meeting of the Antimicrobial Resistance and Healthcare-Associated Infections (ARHAI) Networks, organised by the European Centre of Disease Prevention and Control - Stockholm, 11-13 February 2015
Roundtable of aflatoxin experts on
“Building a multi-stakeholder approach to mitigate aflatoxin contamination of food and feed”
Brussels, Monday 25th January 2016
Low use of antimicrobials and healthy productive animals – a possible equation?SIANI
Presentation by Professor Ulf Magnusson, Swedish University of Agricultural Sciences/ SLU Global at the event: Low use of antimicrobials and healthy productive animals – a possible equation? At FAO Headquarters in Rome, Italy 19th of October, 2016.
Aflatoxin M1-related health risk for milk consumers in dairy farms in rural a...ILRI
Poster by Filipe Maximiano Sousa, Apollinaire Nombre, Amos Miningou, SyAppolinaireTraore, Johanna Lindahl, Augustine Ayantunde, Javier Sanchez and Silvia Alonso presented at the virtual Agriculture, Nutrition and Health (ANH) Academy Week 2021, 29 June – 1 July 2021. Nairobi, Kenya: ILRI.
Monique Denijs (WUR, The Netherlands)
Roundtable of aflatoxin experts on
“Building a multi-stakeholder approach to mitigate aflatoxin contamination of food and feed”
Brussels, Monday 25th January 2016
Epidemiology for strategic control of neglected zoonosesILRI
Presentation by Kohei Makita at an FAO-APHCA/OIE/USDA regional workshop on prevention and control of neglected zoonoses in Asia, Obihiro, Hokkaido, Japan, 15-16 July 2015.
Combining risk assessment and value chain frameworksILRI
Presentation by Theo Knight-Jones at a stakeholder workshop on risk analysis in the Borena-Nazareth-Djibouti livestock value chain, Addis Ababa, Ethiopia, 11-14 August 2015.
Bruno Schuler (GIZ Germany)
Roundtable of aflatoxin experts on
“Building a multi-stakeholder approach to mitigate aflatoxin contamination of food and feed”
Brussels, Monday 25th January 2016
Sarah De Saeger (Faculty of Pharmaceutical Sciences, Ghent University) The expertise of Mycotox at the laboratory of Food Analysis
Roundtable of aflatoxin experts on
“Building a multi-stakeholder approach to mitigate aflatoxin contamination of food and feed”
Brussels, Monday 25th January 2016
Albert Borschette Conference Center, 36 rue Froissart
Comparative characterization of organic and low-input (conventional) beef cattle farms in dehesas. Strcuture, Management, Economics, among other aspects.
Current research on developing collaborations across sectors for zoonoses pre...ILRI
Presentation by Delia Grace at a national expert consultation on intersectoral coordination for prevention and control of zoonoses in India, New Delhi, India, 27 November 2013.
Using choice experiments: Facilitating priority setting in provision of anima...ILRI
The livestock sector is one of the drivers of improved food security and livelihoods in developing countries. Livestock development in Africa is, however, constrained by animal diseases, with major economic, nutritional, and health consequences. Animal health services, especially for the poorest farmers, is generally inaccessible, and of poor quality; characterized by poor uptake of existing control technologies i.e. farmer access. This requires a better understanding of farmer decision-making when faced with animal health choices.
Similar to humans, animals too suffer from chronic diseases. Arthritis and other orthopedic conditions, chronic kidney disease, cancer, hepatitis and other liver diseases, skin allergies, diabetes mellitus, inflammatory bowel disease, and thyroid disorders are among the common chronic diseases in pets.
Experiences about aflatoxins in Serbia: what could be relevant for Africa?Francois Stepman
Experiences about aflatoxins in Serbia: what could be relevant for Africa?
Ferenc Bagi, University of Novi Sad, Serbia (member of the MyToolBox project under H2020- SFS-13-2015 call as well).
Roundtable of aflatoxin experts on
“Building a multi-stakeholder approach to mitigate aflatoxin contamination of food and feed”
Brussels, Monday 25th January 2016
Albert Borschette Conference Center, 36 rue Froissart
ANTIMICROBIAL RESISTANCE PATTERNS AMONG ACINETOBACTER BAUMANNII ISOLATED FROM...inventionjournals
Acinetobacter baumannii (Ab) is a troublesome and increasingly problematic healthcareassociated pathogen, especially in critical care unit (ICU) and cardiovascular internal medicine (CIM). This organism has a capacity for long-term survival in the hospital environment. This study aimed to investigate the drug resistance patterns of Ab strains isolated from Thongnhat Dongnai General Hospital and the relationships between Ab isolations with clinical wards and year of patients. The antibiotic susceptibility of 279 Ab isolates for aminoglycosides, fluro-quinolons, cephalosporins, carbapenems, colistin and bactrim was determined using Kirby-Bauer disk diffusion method. The minimum inhibitor concentration (MIC) of 146 Ab isolates for Meropenem was determined using E-test method according to CLSI guide-line. A total 279 A. baumannii strains out of 1,976 positive isolates were collected from various specimens during study period. Among Ab-positive specimens, the most isolated specimen was sputum (26.6%, χ 2 =161.705 p<0.000),><0.000)><0.000),><0.000). Among 279 Ab isolated, resistance from 53.16% – 63.52% to aminoglycosides, 23.6% – 68.58% to fluroquinolons, 59.61% to 97.93% to cephalosporins, 60.27% to 80.7% to carbapenem, 10.53% to 66.48% to antibiotic combinations, 0.75% to colistin and 61.71% to bactrim. Among 146 multidrug-resistant Ab, 53.42% MICmeropenem ≥ 32 μg/ml and only 18.49% strains were susceptible to Meropenem. Due to the high antimicrobial resistance to two clinical wards (ICU and CIM) and carbapenems by disk agar diffusion test and E-test; we must focus on both a wiser use of antimicrobials and the prevention of infection. Continuous monitoring of antimicrobial susceptibility and strict adherence to infection prevention guidelines are essential to eliminate major outbreaks in the future.
Low use of antimicrobials and healthy productive animals – a possible equation?SIANI
Presentation by Professor Ulf Magnusson, Swedish University of Agricultural Sciences/ SLU Global at the event: Low use of antimicrobials and healthy productive animals – a possible equation? At FAO Headquarters in Rome, Italy 19th of October, 2016.
Aflatoxin M1-related health risk for milk consumers in dairy farms in rural a...ILRI
Poster by Filipe Maximiano Sousa, Apollinaire Nombre, Amos Miningou, SyAppolinaireTraore, Johanna Lindahl, Augustine Ayantunde, Javier Sanchez and Silvia Alonso presented at the virtual Agriculture, Nutrition and Health (ANH) Academy Week 2021, 29 June – 1 July 2021. Nairobi, Kenya: ILRI.
Monique Denijs (WUR, The Netherlands)
Roundtable of aflatoxin experts on
“Building a multi-stakeholder approach to mitigate aflatoxin contamination of food and feed”
Brussels, Monday 25th January 2016
Epidemiology for strategic control of neglected zoonosesILRI
Presentation by Kohei Makita at an FAO-APHCA/OIE/USDA regional workshop on prevention and control of neglected zoonoses in Asia, Obihiro, Hokkaido, Japan, 15-16 July 2015.
Combining risk assessment and value chain frameworksILRI
Presentation by Theo Knight-Jones at a stakeholder workshop on risk analysis in the Borena-Nazareth-Djibouti livestock value chain, Addis Ababa, Ethiopia, 11-14 August 2015.
Bruno Schuler (GIZ Germany)
Roundtable of aflatoxin experts on
“Building a multi-stakeholder approach to mitigate aflatoxin contamination of food and feed”
Brussels, Monday 25th January 2016
Sarah De Saeger (Faculty of Pharmaceutical Sciences, Ghent University) The expertise of Mycotox at the laboratory of Food Analysis
Roundtable of aflatoxin experts on
“Building a multi-stakeholder approach to mitigate aflatoxin contamination of food and feed”
Brussels, Monday 25th January 2016
Albert Borschette Conference Center, 36 rue Froissart
Comparative characterization of organic and low-input (conventional) beef cattle farms in dehesas. Strcuture, Management, Economics, among other aspects.
Current research on developing collaborations across sectors for zoonoses pre...ILRI
Presentation by Delia Grace at a national expert consultation on intersectoral coordination for prevention and control of zoonoses in India, New Delhi, India, 27 November 2013.
Using choice experiments: Facilitating priority setting in provision of anima...ILRI
The livestock sector is one of the drivers of improved food security and livelihoods in developing countries. Livestock development in Africa is, however, constrained by animal diseases, with major economic, nutritional, and health consequences. Animal health services, especially for the poorest farmers, is generally inaccessible, and of poor quality; characterized by poor uptake of existing control technologies i.e. farmer access. This requires a better understanding of farmer decision-making when faced with animal health choices.
Similar to humans, animals too suffer from chronic diseases. Arthritis and other orthopedic conditions, chronic kidney disease, cancer, hepatitis and other liver diseases, skin allergies, diabetes mellitus, inflammatory bowel disease, and thyroid disorders are among the common chronic diseases in pets.
Experiences about aflatoxins in Serbia: what could be relevant for Africa?Francois Stepman
Experiences about aflatoxins in Serbia: what could be relevant for Africa?
Ferenc Bagi, University of Novi Sad, Serbia (member of the MyToolBox project under H2020- SFS-13-2015 call as well).
Roundtable of aflatoxin experts on
“Building a multi-stakeholder approach to mitigate aflatoxin contamination of food and feed”
Brussels, Monday 25th January 2016
Albert Borschette Conference Center, 36 rue Froissart
Similar to Dominique L. Monnet Director del programa ARHAI (Antimicrobial Resistance and Healthcare-Associated Infections) del Centro Europeo para la Prevención y el Control de las Enfermedades (ECDC).
ANTIMICROBIAL RESISTANCE PATTERNS AMONG ACINETOBACTER BAUMANNII ISOLATED FROM...inventionjournals
Acinetobacter baumannii (Ab) is a troublesome and increasingly problematic healthcareassociated pathogen, especially in critical care unit (ICU) and cardiovascular internal medicine (CIM). This organism has a capacity for long-term survival in the hospital environment. This study aimed to investigate the drug resistance patterns of Ab strains isolated from Thongnhat Dongnai General Hospital and the relationships between Ab isolations with clinical wards and year of patients. The antibiotic susceptibility of 279 Ab isolates for aminoglycosides, fluro-quinolons, cephalosporins, carbapenems, colistin and bactrim was determined using Kirby-Bauer disk diffusion method. The minimum inhibitor concentration (MIC) of 146 Ab isolates for Meropenem was determined using E-test method according to CLSI guide-line. A total 279 A. baumannii strains out of 1,976 positive isolates were collected from various specimens during study period. Among Ab-positive specimens, the most isolated specimen was sputum (26.6%, χ 2 =161.705 p<0.000),><0.000)><0.000),><0.000). Among 279 Ab isolated, resistance from 53.16% – 63.52% to aminoglycosides, 23.6% – 68.58% to fluroquinolons, 59.61% to 97.93% to cephalosporins, 60.27% to 80.7% to carbapenem, 10.53% to 66.48% to antibiotic combinations, 0.75% to colistin and 61.71% to bactrim. Among 146 multidrug-resistant Ab, 53.42% MICmeropenem ≥ 32 μg/ml and only 18.49% strains were susceptible to Meropenem. Due to the high antimicrobial resistance to two clinical wards (ICU and CIM) and carbapenems by disk agar diffusion test and E-test; we must focus on both a wiser use of antimicrobials and the prevention of infection. Continuous monitoring of antimicrobial susceptibility and strict adherence to infection prevention guidelines are essential to eliminate major outbreaks in the future.
ANTIMICROBIAL RESISTANCE PATTERNS AMONG ACINETOBACTER BAUMANNII ISOLATED FROM...inventionjournals
Acinetobacter baumannii (Ab) is a troublesome and increasingly problematic healthcareassociated pathogen, especially in critical care unit (ICU) and cardiovascular internal medicine (CIM). This organism has a capacity for long-term survival in the hospital environment. This study aimed to investigate the drug resistance patterns of Ab strains isolated from Thongnhat Dongnai General Hospital and the relationships between Ab isolations with clinical wards and year of patients. The antibiotic susceptibility of 279 Ab isolates for aminoglycosides, fluro-quinolons, cephalosporins, carbapenems, colistin and bactrim was determined using Kirby-Bauer disk diffusion method. The minimum inhibitor concentration (MIC) of 146 Ab isolates for Meropenem was determined using E-test method according to CLSI guide-line. A total 279 A. baumannii strains out of 1,976 positive isolates were collected from various specimens during study period. Among Ab-positive specimens, the most isolated specimen was sputum (26.6%, χ 2 =161.705 p<0.000),><0.000)><0.000),><0.000). Among 279 Ab isolated, resistance from 53.16% – 63.52% to aminoglycosides, 23.6% – 68.58% to fluroquinolons, 59.61% to 97.93% to cephalosporins, 60.27% to 80.7% to carbapenem, 10.53% to 66.48% to antibiotic combinations, 0.75% to colistin and 61.71% to bactrim. Among 146 multidrug-resistant Ab, 53.42% MICmeropenem ≥ 32 μg/ml and only 18.49% strains were susceptible to Meropenem. Due to the high antimicrobial resistance to two clinical wards (ICU and CIM) and carbapenems by disk agar diffusion test and E-test; we must focus on both a wiser use of antimicrobials and the prevention of infection. Continuous monitoring of antimicrobial susceptibility and strict adherence to infection prevention guidelines are essential to eliminate major outbreaks in the future
Presentation from the ECDC expert consultation on Whole Genome Sequencing organised by the European Centre of Disease Prevention and Control - Stockholm, 19 November 2015
A study of antibiotic resistance of Extended-Spectrum Beta-Lactamases produci...Premier Publishers
Background: Extended-Spectrum Beta-Lactamases - producing Enterobacteriaceae are common in hospitals. This study aims to describe the antibiotic resistance of these bacteria and their associated demographic and clinical factors. Methods: It was a prospective study of 73 isolates of Extended-Spectrum Beta-Lactamases - producing Enterobacteriaceae for a period of six months from July to December 2019 in the laboratory of Befelatanana. Results: This study showed 73 (6.3%) isolates of Extended-Spectrum Beta-Lactamases- producing Enterobacteriaceae, represented by 25 (34.2%) isolates of Klebsiella spp, 24 (32.9%) isolates of Escherichia coli, 22 (30.1%) isolates of Enterobacter spp and 2 (2.7%) isolates of Proteus spp. The antibiotic resistance of these bacteria varied from 0% to 100% for all of the antibiotics tested. Resistance to aminoglycosides ranged from 0% (amikacin) to 69.9% (gentamycin). Resistance to quinolones ranged from 43.8% (levofloxacin) to 76.7% (nalidixic acid). Similarly, 60 (82.2%) isolates were resistant to cotrimoxazole and 25 (34.2%) isolates to chloramphenicol. Patients under 20 years (57.1%) (p=0.03), men (52.2%)(p=0.11; NS), patients with respiratory samples (83.3%)(p=0.004), with pus (61.9%)(p=0.02) and hospitalized in surgery and intensive care units (68.4%)(p=0.0009) were the most affected by these enterobacteria. Conclusion: Extended-Spectrum Beta-Lactamases - producing Enterobacteriaceae are responsible for severe infections and the majorities are multi-resistant bacteria.
Keywords: Beta-lactamase, Enterobacteriaceae, antibiotic resistance, amikacin, imipenem.
This is part of our project that aims to assess current state of anti-microbial resistance in Egypt with a specific focus on development of anti-parasitic drugs resistance in addition.
A Study on Pattern of Using Prophylactic Antibiotics in Caesarean Sectioniosrphr_editor
The IOSR Journal of Pharmacy (IOSRPHR) is an open access online & offline peer reviewed international journal, which publishes innovative research papers, reviews, mini-reviews, short communications and notes dealing with Pharmaceutical Sciences( Pharmaceutical Technology, Pharmaceutics, Biopharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy & Phytochemistry, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest........more details on Aim & Scope).
Herbal antimicrobials are considered as an important alternative to antibiotic and probable tools to mitigate emerging antimicrobial-drug-resistance (AMR). However, it is difficult to accept that microbes may not adapt to herbal antimicrobials as rapidly as to antibiotics. This is now well documented that herbal antimicrobial resistance is also common among common pathogenic microbes and genes are now known to encode herbal drug-resistance too. This lecture gives description how resistance to conventional antimicrobials impacts susceptibility of microbes for herbal antimicrobials. Lecture Scheduled on 21st February 2023, In: Antimicrobial Resistance (AMR) in Foodborne pathogens” sponsored under the ICAR-NAHEP-CAAST project by the MAFSU, Mumbai Veterinary College, at the Division of Veterinary Public Health, ICAR-IVRI from 20th February to 25th February, 2023.
TiPE™ is a leading nano science-based company active in catalyst, bactericide, optical and high performance sol materials. By connecting its unique competences in Nano Sciences and Materials Sciences, TiPE is driving economic prosperity, environmental progress and social advances to create sustainable mutual success for all of our partners and customers simultaneously. We delivers innovative and advanced solutions that improve performance in global markets such as food and agriculture producing, personal care, health, medical devices, automotive, transportation, construction, building maintenance, historic preservation, paints, public services, alternative energy and nano-based functional materials.
Presentation from the 3rd Joint Meeting of the Antimicrobial Resistance and Healthcare-Associated Infections (ARHAI) Networks, organised by the European Centre of Disease Prevention and Control - Stockholm, 11-13 February 2015
The lecture describes the performance and presentation of the antibiograms by the hospitals based upon recommendations of CLSI and shows experience of some of our MOH hospitals with the advantages and pitfalls in them.
articulo descripcion y analisis del articuloyessica756439
articulo
Similar to Dominique L. Monnet Director del programa ARHAI (Antimicrobial Resistance and Healthcare-Associated Infections) del Centro Europeo para la Prevención y el Control de las Enfermedades (ECDC). (20)
El jueves 24 de mayo del 2018 organizamos una Conferencia con Antonio Cabrales en la Fundación Ramón Areces. Una conferencia en la cual el tema fue: Estilo negociador y confianza, ¿hay diferencias entre hombres y mujeres?
Teresa Puig - Institut de Ciència de Materials de Barcelona, ICMAB-CSIC, Espa...Fundación Ramón Areces
El lunes y martes 21 y 22 de mayo del 2018 realizamos un Simposio Internacional en la Fundación Ramón Areces, tratando el tema de la superconductividad y presión: una relación fructífera en el camino hacia la superconductividad a temperatura ambiente.
Elena Bascones - Instituto de Ciencia de Materiales de Madrid (ICMM-CSIC), Es...Fundación Ramón Areces
El lunes y martes 21 y 22 de mayo del 2018 realizamos un Simposio Internacional en la Fundación Ramón Areces, tratando el tema de la superconductividad y presión: una relación fructífera en el camino hacia la superconductividad a temperatura ambiente.
El jueves 17 de mayo del 2018 se organizó una Mesa Redonda en la Fundación Ramón Areces, en la cual se habló sobre las subidas de tipos en la era Trump y la nueva globalización.
El jueves 17 de mayo del 2018 se organizó una Mesa Redonda en la Fundación Ramón Areces, en la cual se habló sobre las subidas de tipos en la era Trump y la nueva globalización.
El miércoles 16 de mayo del 2018 celebramos una Jornada en la Fundación Ramón Areces, en la cual se habló sobre las nuevas fronteras de investigación sobre la distribución comercial y el comportamiento del consumidor.
El miércoles 16 de mayo del 2018 celebramos una Jornada en la Fundación Ramón Areces, en la cual se habló sobre las nuevas fronteras de investigación sobre la distribución comercial y el comportamiento del consumidor.
Juan Carlos López-Gutiérrez - Unidad de Anomalías Vasculares, Hospital Unive...Fundación Ramón Areces
El jueves y viernes 10 y 11 de mayo del 2018 realizamos en la Fundación Ramón Areces un Simposio Internacional, en el cual se trató el tema del mosaicismo somático en malformaciones vasculares.
Víctor Martínez-Glez. - Instituto de Genética Médica y Molecular (INGEMM). I...Fundación Ramón Areces
El jueves y viernes 10 y 11 de mayo del 2018 realizamos en la Fundación Ramón Areces un Simposio Internacional, en el cual se trató el tema del mosaicismo somático en malformaciones vasculares.
Rudolf Happle - Dermatología, University of Freiburg Medical Center, Freiburg...Fundación Ramón Areces
El jueves y viernes 10 y 11 de mayo del 2018 realizamos en la Fundación Ramón Areces un Simposio Internacional, en el cual se trató el tema del mosaicismo somático en malformaciones vasculares.
Rafael Doménech - Responsable de Análisis Macroeconómico, BBVA Research. Fundación Ramón Areces
El martes 8 de mayo de 2018 realizamos una conferencia en la Fundación Ramón Areces, en la cual se habló sobre el futuro de las pensiones: una visión global.
El martes 8 de mayo de 2018 realizamos una conferencia en la Fundación Ramón Areces, en la cual se habló sobre el futuro de las pensiones: una visión global.
El martes 8 de mayo de 2018 realizamos una conferencia en la Fundación Ramón Areces, en la cual se habló sobre el futuro de las pensiones: una visión global.
Nicholas Barr - Profesor de Economía Pública, London School of Economics. Fundación Ramón Areces
El martes 8 de mayo de 2018 realizamos una conferencia en la Fundación Ramón Areces, en la cual se habló sobre el futuro de las pensiones: una visión global.
El viernes 27 de abril del 2018 se celebró en la Fundación Ramón Areces una Jornada sobre física , en la cual se trataron diversos temas como: Los materiales mecanocalóricos, magnetísmo, biofísica, la energía oscura y instrumentación astronómica.
El viernes 20 de abril organizamos una Jornada sobre la ciencia en el corazón de Europa, en colaboración con Científicos Españoles en Bélgica (CEBE) y realizada en la Fundación Ramón Areces.
Marta Olivares - Investigadora Postdoctoral en Université catholique de Louva...Fundación Ramón Areces
El viernes 20 de abril organizamos una Jornada sobre la ciencia en el corazón de Europa, en colaboración con Científicos Españoles en Bélgica (CEBE) y realizada en la Fundación Ramón Areces.
El viernes 20 de abril organizamos una Jornada sobre la ciencia en el corazón de Europa, en colaboración con Científicos Españoles en Bélgica (CEBE) y realizada en la Fundación Ramón Areces.
Víctor R. de la Rosa - Investigador en Universiteit Gent (UGent) y fundador d...Fundación Ramón Areces
El viernes 20 de abril organizamos una Jornada sobre la ciencia en el corazón de Europa, en colaboración con Científicos Españoles en Bélgica (CEBE) y realizada en la Fundación Ramón Areces.
El viernes 20 de abril organizamos una Jornada sobre la ciencia en el corazón de Europa, en colaboración con Científicos Españoles en Bélgica (CEBE) y realizada en la Fundación Ramón Areces.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...
Dominique L. Monnet Director del programa ARHAI (Antimicrobial Resistance and Healthcare-Associated Infections) del Centro Europeo para la Prevención y el Control de las Enfermedades (ECDC).
1. Dominique L. Monnet, on behalf of ECDC Antimicrobial Resistance and
Healthcare-Associated Infections (ARHAI) Programme, ECDC
Madrid, 5 June 2018
Antimicrobial consumption and
resistance in humans in the EU and
conclusions from the ECDC-EFSA-
EMA JIACRA report
2. • An agency of the European Union, located in Stockholm, Sweden
• Founded in 2005; nearly 300 employees
• Mandate to ‘identify, assess and communicate current and emerging
threats to human health from communicable diseases’
• European Union (EU) (28) and European Economic Area (EEA) (3) =
31 countries with a total of more than 500 million people
ECDC – European Centre for Disease
Prevention and Control
3 April 2018
www.ecdc.europa.eu
3. Several, inter-related compartments of healthcare,
i.e. patients in primary care, hospitals, nursing
homes and long-term care facilities, food animals,
food, environment)
Many types of infection, i.e. respiratory tract,
urinary tract, skin and soft tissue, bloodstream,
surgical site, related to medical devices, etc.)
Many bacteria/microorganisms
Many antimicrobials
Many different genes and mechanisms of resistance
Spread of clones…
… and of resistance genes between bacteria…
Antimicrobial resistance (AMR):
what does it mean?
5. each year in the EU/EEA
attributable to
5 multidrug-resistant bacteria
4 main healthcare-associated infections (HAIs)
Burden of antimicrobial resistance (AMR)
for the EU/EEA
Update: November 2018
Source: ECDC, 2009.
In: http://ecdc.europa.eu/en/publications/Publications/0909_TER_The_Bacterial_Challenge_Time_to_React.pdf
25 000 deaths
6. Comparing the burden of healthcare-
associated infections (HAIs) with that
of other infectious diseases
HAIs
account for twice the burden
of 31 other infectious diseases
Burden of HAIs – 2011-2012 *
Burden of 5 top ranking infectious diseases from BCoDE 2009-2013 **
Source: *Cassini A, et al. PLoS Med 2016;13(10):e1002150 (18 October 2016)
** Cassini A, et al. Euro Surveill. 2018;23(16):pii=17-00454 (19 April 2018).
HAI, Healthcare-associated; DALYs: Disability-Adjusted Life Years
7. How does antimicrobial resistance
spread?
Source: Antibiotic resistance threats in the United States 2013. US CDC,2013.
10. 2nd Joint Interagency Antimicrobial Consumption
and Resistance Analysis (JIACRA) Report, 2017
ECDC/EFSA/EMA second joint report on the integrated analysis of the consumption
of antimicrobial agents and occurrence of antimicrobial resistance in bacteria from
humans and food-producing animals
Purpose
To provide an integrated analysis of relationships between antimicrobial
consumption (AMC) in human and veterinary medicine and the occurrence of
antimicrobial reistance (AMR) in bacteria from humans and food-producing animals
Source: ECDC, EFSA & EMA, 2017. EFSA Journal, 27 July 2017.
http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2017.4872/epdf
3rd report:
December 2020
11. JIACRA reports
• Analysis performed on data from five EU-wide surveillance
networks managed by the three agencies (ECDC, EFSA, EMA)
• Presents results of analysis to assess the relationship between
AMC and AMR in food-producing animals and humans
• Conclusions and recommendations in a one-health perspective
based on results of integrated analysis of data (logistic regression
and multivariate analysis)
Source: ECDC, EFSA & EMA, 2017. EFSA Journal, 27 July 2017.
http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2017.4872/epdf
13. Source: ECDC, EFSA & EMA, 2017. EFSA Journal, 27 July 2017.
http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2017.4872/epdf
Biomass-corrected
antimicrobial consumption
in humans and animals,
EU/EEA, 2014
Humans: 124 mg/kg (range: 50 – 182 mg/kg)
Animals: 152 mg/kg (range: 3 – 419 mg/kg)
* Humans: community consumption only
14. Biomass-corrected antimicrobial
consumption in humans and
animals, EU/EEA, 2014 (2)
Source: ECDC, EFSA & EMA, 2017. EFSA Journal, 27 July 2017.
http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2017.4872/epdf
Fluoroquinolones and other quinolones
3rd- and 4th-generation cephalosporins
* Humans: community consumption only
15. Joint Interagency Antimicrobial Consumption
and Resistance Analysis (JIACRA): example
Each dot represent one country.
Poultry
Quinolone consumption and
probability of resistance to
quinolones in Campylobacter jejuni
from poultry, EU/EEA, 2014
OR = 2.71 [1.57 – 5.63], p < 0.001
Source: ECDC, EFSA & EMA, 2017. EFSA Journal, 27 July 2017.
http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2017.4872/epdf
16. Joint Interagency Antimicrobial Consumption
and Resistance Analysis (JIACRA):
Results of partial least square path modeling (PLS-PM)
of fluoroquinolone consumption and fluoroquinolone-
resistant Salmonella spp.
Source: ECDC, EFSA & EMA, 2017. EFSA Journal, 27 July 2017.
http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2017.4872/epdf
17. Joint Interagency Antimicrobial Consumption
and Resistance Analysis (JIACRA):
Results of partial least square path modeling (PLS-PM)
of fluoroquinolone consumption and fluoroquinolone-
resistant Campylobacter jejuni
Source: ECDC, EFSA & EMA, 2017. EFSA Journal, 27 July 2017.
http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2017.4872/epdf
20. R2=0.54
P=0.006
R2=0.63
P=0.001
Relationship between antibiotic use
and resistance in the community
Source: Monnet DL. Enferm Infecc Microbiol Clin. 2010;28 (Suppl 4):1-3.
Spain only reports data on reimbursed antibiotic prescription to ESAC. To better represent antibiotic sales and therefore exposure of the Spanish
population to antibiotics correction factors were applied to ESAC data based on Campos J, et al. J Antimicrob Chemother. 2007;60:698-701-11.
21. Antimicrobial Resistance and Healthcare-
Associated Infections (ARHAI) Networks
• European Antimicrobial Resistance
Surveillance Network (EARS-Net)
(formerly EARSS, integrated in January 2010)
• European Surveillance of
Antimicrobial Consumption
Network (ESAC-Net)
(formerly ESAC, integrated in July 2011)
• Healthcare-Associated Infections
surveillance Network (HAI-Net)
(formerly HELICS / IPSE, integrated in July 2008)
www.ecdc.europa.eu
22. Source: ESAC-Net, 2017.
Sweden
Finland
The symbols and indicate a significant increasing or decreasing trend for the period 2012-2016, respectively.
Defined daily doses
(DDD) per 1000 inh. and per day
Packages
per 1000 inh. and per day
* Total care data, including
the hospital sector.
† Reimbursement data
(i.e. not including consumption
without a prescription and
other non-reimbursed courses).
Consumption of antibiotics for
systemic use (ATC group J01) in
the community, EU/EEA, 2012-2016
Norway
Spain†
Greece
Luxembourg
Sweden
Denmark
Estonia
Finland
†
24. Streptococcus pneumoniae: % of invasive
isolates with resistance to macrolides,
EU/EEA, 2006 & 2016
Source: EARS/EARS-Net, 2017 (https://atlas.ecdc.europa.eu).
2006
2016
25. H
R Strep.
pneumoniae
R Strep.
pyogenes
R Haem.
influenzae
R Salmonella
R Campylo-
bacter
R E. coli
R E. coli
HA-MRSA
CA-MRSA
LA-MRSA
(mostly
CC398)
R E. coli
R Salmonella
R Campylo-
bacter
R
Enterobacter
R
Klebsiella
pneumoniae
Clostridium
difficile
R
Pseudomonas
aeruginosa
R
Acinetobacter
baumannii
Compartments of antimicrobial resistance
26. Joint Interagency Antimicrobial Consumption
and Resistance Analysis (JIACRA):
Results of partial least square path modeling (PLS-PM)
of fluoroquinolone consumption and fluoroquinolone-
resistant Escherichia coli
Source: ECDC, EFSA & EMA, 2017. EFSA Journal, 27 July 2017.
http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2017.4872/epdf
27. Joint Interagency Antimicrobial Consumption
and Resistance Analysis (JIACRA):
Results of partial least square path modeling (PLS-PM)
of third-generation cephalosporin (3GC) consumption
and 3GC-resistant Escherichia coli
Source: ECDC, EFSA & EMA, 2017. EFSA Journal, 27 July 2017.
http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2017.4872/epdf
28. MDR* MDR MDR,XDR,PDRMDR
H
~ 90% DDDs
Imported animals
Imported foods
International travel Cross-border transfer of patients
152 mg/kg
(country range:
3 – 419 mg/kg)
ICU & Haem./
bone marrow
transplant (BMT)
Antimicrobial consumption and AMR:
a continuum of risks in our societies
124 mg/kg (country range: 50 – 182 mg/kg)
~ 10% DDDs
2% (1-4%)
population
on a given day
35% (21-55%) patients on a given day
59% patients
Source: ECDC/EFSA/EMA JIACRA report, 2017; ECDC ESAC-Net 2016; ECDC PPS, 2013.
. *MDR, multidrug-resistant; XDR, extensively drug-resistant; PDR, pandrug-resistant
30. Source: EARS/EARS-Net, 2017 (https://atlas.ecdc.europa.eu).
2006
2016
Staphylococcus aureus: % of invasive
isolates with resistance to meticillin
(MRSA), EU/EEA, 2006 & 2016
31. Source: EARS/EARS-Net, 2017 (https://atlas.ecdc.europa.eu).
2006
2016
Klebsiella pneumoniae: % of invasive
isolates with resistance to carbapenems,
EU/EEA, 2006 & 2016
32. Joint Interagency Antimicrobial Consumption
and Resistance Analysis (JIACRA): example
Humans
Carbapenem consumption and probability
of resistance to carbapenems in invasive
Klebsiella pneumoniae from humans,
EU/EEA, 2015
OR = 1.23 [95% CI: 1.08 – 1.42], p = 0.002
Each dot represent one country.
Source: ECDC, EFSA & EMA, 2017. EFSA Journal, 27 July 2017.
http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2017.4872/epdf
33. Source: ESAC-Net, 2017.The symbols and indicate a significant increasing or decreasing trend for the period 2012-2016, respectively.
Consumption of last-line antibiotics in
the hospital sector, EU/EEA, 2012-2016
Carbapenems
(DDD per 1000 inh. and per day)
Polymyxins (mainly colistin)
(DDD per 1000 inh. and per day)
* Cyprus and Romania:
total care data,
including consumption
in the community.
These data were not
used to calculate the
EU/EEA population-
weighted average.
(a) Finland: data include
consumption in remote
primary healthcare
centres and nursing
homes.
(b) Portugal: data relate to
public hospitals only.
Greece
Slovakia
Italy
Romania
Malta
Hungary
Slovenia
Denmark
Bulgaria
Ireland
France
Bulgaria
Latvia
Hungary
Lithuania
Slovakia
Romania
Estonia
Croatia
Malta
Cyprus
Portugal (b)
34. Source: EARS-Net, 2017
2016
Klebsiella pneumoniae: % of invasive
isolates with combined resistance to
carbapenems and colistin, EU/EEA, 2016
All isolates tested for carbapenem susceptibility were included in the denominator to limit the effect
of sequential testing.
35. Adapted from: Fournier S, et al. Eurosurveillance (22 February 2018).
No. of carbapenemase-producing Enterobacteriaceae (CPE)
and glycopeptide-resistant Enterococcus faecium (GRE)
introductions and proportions of outbreaks in Paris, France,
2010-2015
CPE, carbapenemase-producing Enterobacteriaceae; GRE, glycopeptide-resistant Enterococcus faecium.
GRE introductions
CPE introductions
Proportion of outbreaks among CPE or GRE introductions
CPEandGREintroductions(No.)
Proportionofoutbreaksamong
CPEorGREintroductions(%)
36. Adapted from: Fournier S, et al. Eurosurveillance (22 February 2018).
Proportion of outbreaks and secondary cases of
carbapenemase-producing Enterobacteriaceae (CPE) and
glycopeptide-resistant Enterococcus faecium (GRE)
according to measures implemented within the first two days
around an index case, Paris, France, 2010-2015
CPE, carbapenemase-producing Enterobacteriaceae; GRE, glycopeptide-resistant Enterococcus faecium.
Proportion of outbreaks (n=103)
among CPE or GRE introductions (n=901)
Proportion of secondary cases (n=427)
among CPE or GRE cases (n=1,328)
CPE or GRE introductions without outbreaks
Outbreaks
CPE or GRE introductions (index cases)
Secondary cases
37. Source: EARS/EARS-Net, 2017 (https://atlas.ecdc.europa.eu).
2006
2016
Enterococcus faecium: % of invasive
isolates with resistance to vancomycin,
EU/EEA, 2006 & 2016
38. Source: EARS/EARS-Net, 2017 (https://atlas.ecdc.europa.eu).
2012
2016
Acinetobacter spp.: % of invasive
isolates with combined resistance*,
EU/EEA, 2012 & 2016
*Fluoroquinolones,
aminoglycosides and carbapenems
39. 2nd ECDC point prevalence survey (PPS)
of healthcare-associated infections and
antimicrobial use in European acute care
hospitals, 2016-2017
MRSA
Carb-R
kpn
VRE
CDI
3GC-R
eco
3GC-R
kpn
ALERT
MDRO
Carb-R
aci
MRSA
guidance
CDI
guidance
CPE/CRE
guidance
ABS
guidance
IPC prog.
guidance
Hand hygiene
guidance
Outcome
indicators
(HAI,
selected MDROs)
Structure and
process indicators
(incl. antimicrobial
consumption)
Guidance
(directory of online
resources)
Hospital
indicators
(tbd)
IPC
SPIs
Hand
hygiene
ABS
SPIs
AMC
Source: ECDC, 2015.
ECDC report:
November 2018
41. • Based on Council Recommendation
of 15 November 2001 on the
prudent use of antimicrobial agents
in human medicine (2002/77/EC)
• Reports (observations, conclusions,
suggestions, examples of best
practice)
• 24 EU Member States,
1 EEA country and 1 EU
enlargement country (see map)
• 5 follow-up visits (Greece × 2 and
Hungary × 2, Malta)
• 2018: 4 additional visits
*jointly with DG SANTE/F5,
in a One Health perspective
Country visits to discuss antimicrobial
resistance (AMR) issues, 2006-2018
As of 4 June 2018
Done
Planned (invitation received)
Discussed
Jointly with DG SANTE/F
*
*
*
*
Source: ECDC, 2018. Country visit reports: https://ecdc.europa.eu/en/infectious-diseases-public-
health/antimicrobial-resistance/preparedness/country-visits-reports
*
*
43. JIACRA main conclusions and
recommendations (1)
• The total and average population-weighted antimicrobial
consumption (AMC) was higher in animals than in humans, although
in 2/3 of the countries, AMC was lower in animals than in humans.
This indicates that a low number of countries accounts for a large
proportion of AMC in animals.
• The results for both humans and animals indicate that there is a
strong impact of AMC on the occurrence of AMR in both sectors.
Measures to reduce AMC would therefore most likely help to prevent
and control the spread of AMR in a one-health-perspective.
• Substantial variation in AMC across countries and in both humans
and animals was observed. This indicates that in some countries,
there is a large potential for improving prudent use in order to
reduce the occurrence of AMR in a one-health-perspective.
Source: ECDC, EFSA & EMA, 2017. EFSA Journal, 27 July 2017.
http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2017.4872/epdf
44. JIACRA main conclusions and
recommendations (2)
• Multivariate analysis proved a useful approach to assess the effect
on AMR in bacteria in humans from AMR in bacteria from animals
and AMC in both animals and humans.
• For AMR in Salmonella and Campylobacter, strong associations
between the animal and human sector were observed. This indicates
that AMR in zoonotic bacteria in animals is of significance to AMR in
humans in a one-health-perspective.
• Inherent sector specific characteristics of the systems for collection
and reporting data on AMC and AMR in bacteria from humans and
animals hampers direct comparisons.
• Dedicated studies to collect data specifically for integrated analysis
could allow for more precise assessments of the association between
the two sectors and could address specific one-health related
questions of interest.
Source: ECDC, EFSA & EMA, 2017. EFSA Journal, 27 July 2017.
http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2017.4872/epdf
45. Humans + Animals = One Health
Prudent use of antibiotics.
Everyone is responsible!