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DISEASES OF THE CONJUNCTIVA
APPLIED ANATOMY
• The conjunctiva is a translucent mucous membrane which lines the
posterior surface of the eyelids and anterior aspect of eyeball.
• Parts of conjunctiva;
- Palpebral conjunctiva
- Bulbar conjunctiva
- Conjunctival fornix
PALBEBRAL CONJUCTIVA
CONJUNCTIVAL FORNIX
BULBAR CONJUCTIVA
DISEASE CLASSIFICATION
INFLAMMATIONS OF
CONJUNCTIVA
• Infective conjunctivitis –
- Bacterial
- Viral
- Chlamydial
• Allergic conjunctivitis
• Granulomatous conjunctivitis
DEGENERATIVE CONDITIONS
• Pinguecula
• Pterygium
• Concretions
SYMPTOMATIC CONDITIONS
• Hyperemia
• Xerosis
• Discoloration
• Sub conjunctival haemorrhage
• Chemosis
CONJUNCTIVITIS
• Conjunctivitis means inflammation of the
conjunctiva.
• Conjunctivitis is the commonest single diagnosis in
eye clinics throughout Africa.
ALL PATIENTS WITH CONJUNCTIVITIS HAVE SOME
SYMPTOMS AND SIGNS IN COMMON
1) Pain/Discomfort - usually described as a "foreign body
sensation"
2) Redness - The conjunctiva is red and inflamed.
3) Discharge - usually sticky, but also watery, or mucous.
DISCHARGE
1) Watery discharge is composed of a serous exudate and tears
and occurs in acute viral or acute allergic conjunctivitis
2) Mucoid discharge is typical of chronic allergic conjunctivitis
and dry eye
3) Mucopurulent discharge typically occurs in chlamydial or
acute bacterial infection
4) Moderately purulent discharge occurs in acute bacterial
conjunctivitis
5) Severe purulent discharge is typical of gonococcal infection
SIGNS OF CONJUNCTIVAL INFLAMMATION
(A) INJECTION; (B) HAEMORRHAGES; (C) CHEMOSIS; (D) PSEUDOMEMBRANE; (E) INFILTRATION; (F) SUBCONJUNCTIVAL
SCARRING
CONJUCTIVITIS
• It can be divided into:
1) Bacterial
2) Viral
3) Allergic
4) Chlamydial
5) Chemical
6) Granulomatous
BACTERIAL CONJUNCTIVITIS
• Commonly caused by Staphylococcus Aureus
• The patient has a gritty eye, with a purulent discharge
• The conjunctiva is red, particularly in the lower fornix,
where a purulent discharge may be visible
• The condition is self-limiting, but can be treated with
topical antibiotics, or regular face-washing
SIGNS AND SYMPTOMS
BACTERIAL CONJUNCTIVITIS - PURULENT DISCHARGE WITH MATTING OF EYELASHES
BACTERIAL CONJUNCTIVITIS. (A) EYELID EDEMA AND ERYTHEMA IN SEVERE INFECTION; (B) DIFFUSE CONJUNCTIVAL INJECTION
INVOLVING THE TARSAL AND FORNICEAL CONJUNCTIVA; (C) MUCOPURULENT DISCHARGE; (D) PROFUSE PURULENT DISCHARGE; (E)
SUPERIOR CORNEAL ULCERATION; (F) GRAM STAIN SHOWS KIDNEY-SHAPED DIPLOCOCCIC
GONOCOCCAL CONJUNCTIVITIS
• Rare but very serious form of bacterial conjunctivitis
caused by Neisseria Gonorrhea
• It usually affects very young babies, about 3-10 days old.
They become infected from their mother's genital tract
during birth
• The eyelids are very swollen, and there is a profuse
purulent discharge. Within 24 hours both corneas can be
totally destroyed and the child will be permanently blind
• Gonococcal conjunctivitis can also occur in adults
• Patients with a severe purulent conjunctivitis need an
immediate swab and gram stain of their discharge
• Treatment with half-hourly antibiotic drops, and
appropriate systemic treatment for gonorrhoea.
• (OPhthalmia neonatorum) can be prevented by cleaning the
eyes of babies at birth
• Additional protection may be provided by giving a drop of an
antibiotic or disinfectant (such as Silver Nitrate or Povidine
Iodine) into each eye.
VIRAL CONJUCTIVITIS
• Inflammation of the conjuctiva caused by the virus
• The two commonest viruses causing viral conjunctivitis outbreaks are:
-Adenovirus group
-Enterovirus 70 group
• Mainly occur in epidemics (schools work place)
• Transmitted by fingers, swimming pools
• The most common cause of viral conjunctivitis is adeno virus
SIGNS AND SYMPTOMS
ADENOVIRUS
• Adenovirus causes severe conjunctivitis, which may last for up to
four weeks
• Can be associated with small sub-epithelial corneal opacities,
which may take up to six months to disappear
• The patient will have follicles in the upper and lower fornices,
and the corneal opacities may be visible
• There is no specific treatment
ENTEROVIRUS70 GROUP
• Enterovirus causes acute hemorrhagic conjunctivitis
• This is a milder form of conjunctivitis, accompanied by sub-
conjunctival hemorrhages, which make the eye look worse
than it really is
• There is no specific treatment
• The condition resolves spontaneously in 1-2 weeks.
PRECAUTION
• Both types of viral conjunctivitis are very infectious, and
great care must be taken to avoid transmitting the disease
to other patients or to yourself!
ALLERGIC CONJUNCTIVITIS
• This is the most common form of conjunctivitis
• vernal catarrh is the commonest form of allergic conjuctivitis
• This is a chronic allergic condition that lasts 5-7 years before spontaneously
resolving
• It is common in young people, but rare in anyone over 20 years old
• It is found in cooler, higher areas of Kenya
SIGNS AND SYMPTOMS
• Itchy eyes,
• mucoid or watery discharge
• There are two types of vernal catarrh, limbal and tarsal.
• Patients with limbal vernal catarrh have large papillae around the limbus
• Those with tarsal vernal catarrh have papillae on the upper tarsal plate
• Many patients have both, but with one or other type predominating
TARSAL VERNAL DISEASE. (A) DIFFUSE PAPILLARY HYPERTROPHY; (B) MACROPAPILLAE; (C) GIANT PAPILLAE AND MUCUS;
(D) RELATIVELY INACTIVE DISEASE
LIMBAL VERNAL DISEASE. (A) SPARSE LIMBAL PAPILLAE; (B) PAPILLAE WITH HORNER–TRANTAS DOTS; (C) EXTENSIVE
PAPILLAE; (D) EXTREMELY SEVERE INVOLVEMENT
RX OF ALLERGIC CONJUNCTIVITIS
• Topical steroid drops make the eye feel much better, but the
disease recurs when the drops are stopped
• Long-term use of steroid drops may cause blindness
• Systemic steroids are more effective, but even more dangerous
• Unless there is corneal ulceration, oral steroids should be
avoided
• The patient can be reassured that the disease will get
better
• Immediate symptomatic relief can be obtained by washing
the eyes with clean cold water.
• Mast cell stabilizers drops
• Antihistamine drops
• Soothing agents
CHEMICAL CONJUNCTIVITIS
This is caused by exposure to an irritant chemical such as
• acids,
• tobacco
• smoke,
• snake venom, or the
• sap of certain trees- particularly Euphorbia spp.
PRESENTATION/RX
• There is usually hx of chemical entering the eye
• Patient has painful, watering, red eye
• If exposure took place within the preceding few hours, it
may be helpful to irrigate the conjunctival sac
• Antibiotic drops should be given to prevent secondary
infection
THANKS

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Diseases of the conjuctiva II.pptx

  • 1. DISEASES OF THE CONJUNCTIVA
  • 2. APPLIED ANATOMY • The conjunctiva is a translucent mucous membrane which lines the posterior surface of the eyelids and anterior aspect of eyeball. • Parts of conjunctiva; - Palpebral conjunctiva - Bulbar conjunctiva - Conjunctival fornix
  • 6. DISEASE CLASSIFICATION INFLAMMATIONS OF CONJUNCTIVA • Infective conjunctivitis – - Bacterial - Viral - Chlamydial • Allergic conjunctivitis • Granulomatous conjunctivitis DEGENERATIVE CONDITIONS • Pinguecula • Pterygium • Concretions
  • 7. SYMPTOMATIC CONDITIONS • Hyperemia • Xerosis • Discoloration • Sub conjunctival haemorrhage • Chemosis
  • 8. CONJUNCTIVITIS • Conjunctivitis means inflammation of the conjunctiva. • Conjunctivitis is the commonest single diagnosis in eye clinics throughout Africa.
  • 9. ALL PATIENTS WITH CONJUNCTIVITIS HAVE SOME SYMPTOMS AND SIGNS IN COMMON 1) Pain/Discomfort - usually described as a "foreign body sensation" 2) Redness - The conjunctiva is red and inflamed. 3) Discharge - usually sticky, but also watery, or mucous.
  • 10. DISCHARGE 1) Watery discharge is composed of a serous exudate and tears and occurs in acute viral or acute allergic conjunctivitis 2) Mucoid discharge is typical of chronic allergic conjunctivitis and dry eye 3) Mucopurulent discharge typically occurs in chlamydial or acute bacterial infection 4) Moderately purulent discharge occurs in acute bacterial conjunctivitis 5) Severe purulent discharge is typical of gonococcal infection
  • 11. SIGNS OF CONJUNCTIVAL INFLAMMATION (A) INJECTION; (B) HAEMORRHAGES; (C) CHEMOSIS; (D) PSEUDOMEMBRANE; (E) INFILTRATION; (F) SUBCONJUNCTIVAL SCARRING
  • 12. CONJUCTIVITIS • It can be divided into: 1) Bacterial 2) Viral 3) Allergic 4) Chlamydial 5) Chemical 6) Granulomatous
  • 13. BACTERIAL CONJUNCTIVITIS • Commonly caused by Staphylococcus Aureus • The patient has a gritty eye, with a purulent discharge • The conjunctiva is red, particularly in the lower fornix, where a purulent discharge may be visible • The condition is self-limiting, but can be treated with topical antibiotics, or regular face-washing
  • 15. BACTERIAL CONJUNCTIVITIS - PURULENT DISCHARGE WITH MATTING OF EYELASHES
  • 16.
  • 17. BACTERIAL CONJUNCTIVITIS. (A) EYELID EDEMA AND ERYTHEMA IN SEVERE INFECTION; (B) DIFFUSE CONJUNCTIVAL INJECTION INVOLVING THE TARSAL AND FORNICEAL CONJUNCTIVA; (C) MUCOPURULENT DISCHARGE; (D) PROFUSE PURULENT DISCHARGE; (E) SUPERIOR CORNEAL ULCERATION; (F) GRAM STAIN SHOWS KIDNEY-SHAPED DIPLOCOCCIC
  • 18. GONOCOCCAL CONJUNCTIVITIS • Rare but very serious form of bacterial conjunctivitis caused by Neisseria Gonorrhea • It usually affects very young babies, about 3-10 days old. They become infected from their mother's genital tract during birth • The eyelids are very swollen, and there is a profuse purulent discharge. Within 24 hours both corneas can be totally destroyed and the child will be permanently blind • Gonococcal conjunctivitis can also occur in adults
  • 19.
  • 20. • Patients with a severe purulent conjunctivitis need an immediate swab and gram stain of their discharge • Treatment with half-hourly antibiotic drops, and appropriate systemic treatment for gonorrhoea.
  • 21.
  • 22. • (OPhthalmia neonatorum) can be prevented by cleaning the eyes of babies at birth • Additional protection may be provided by giving a drop of an antibiotic or disinfectant (such as Silver Nitrate or Povidine Iodine) into each eye.
  • 23. VIRAL CONJUCTIVITIS • Inflammation of the conjuctiva caused by the virus • The two commonest viruses causing viral conjunctivitis outbreaks are: -Adenovirus group -Enterovirus 70 group • Mainly occur in epidemics (schools work place) • Transmitted by fingers, swimming pools • The most common cause of viral conjunctivitis is adeno virus
  • 25. ADENOVIRUS • Adenovirus causes severe conjunctivitis, which may last for up to four weeks • Can be associated with small sub-epithelial corneal opacities, which may take up to six months to disappear • The patient will have follicles in the upper and lower fornices, and the corneal opacities may be visible • There is no specific treatment
  • 26. ENTEROVIRUS70 GROUP • Enterovirus causes acute hemorrhagic conjunctivitis • This is a milder form of conjunctivitis, accompanied by sub- conjunctival hemorrhages, which make the eye look worse than it really is • There is no specific treatment • The condition resolves spontaneously in 1-2 weeks.
  • 27. PRECAUTION • Both types of viral conjunctivitis are very infectious, and great care must be taken to avoid transmitting the disease to other patients or to yourself!
  • 28. ALLERGIC CONJUNCTIVITIS • This is the most common form of conjunctivitis • vernal catarrh is the commonest form of allergic conjuctivitis • This is a chronic allergic condition that lasts 5-7 years before spontaneously resolving • It is common in young people, but rare in anyone over 20 years old • It is found in cooler, higher areas of Kenya
  • 29. SIGNS AND SYMPTOMS • Itchy eyes, • mucoid or watery discharge • There are two types of vernal catarrh, limbal and tarsal. • Patients with limbal vernal catarrh have large papillae around the limbus • Those with tarsal vernal catarrh have papillae on the upper tarsal plate • Many patients have both, but with one or other type predominating
  • 30. TARSAL VERNAL DISEASE. (A) DIFFUSE PAPILLARY HYPERTROPHY; (B) MACROPAPILLAE; (C) GIANT PAPILLAE AND MUCUS; (D) RELATIVELY INACTIVE DISEASE
  • 31. LIMBAL VERNAL DISEASE. (A) SPARSE LIMBAL PAPILLAE; (B) PAPILLAE WITH HORNER–TRANTAS DOTS; (C) EXTENSIVE PAPILLAE; (D) EXTREMELY SEVERE INVOLVEMENT
  • 32.
  • 33. RX OF ALLERGIC CONJUNCTIVITIS • Topical steroid drops make the eye feel much better, but the disease recurs when the drops are stopped • Long-term use of steroid drops may cause blindness • Systemic steroids are more effective, but even more dangerous • Unless there is corneal ulceration, oral steroids should be avoided
  • 34. • The patient can be reassured that the disease will get better • Immediate symptomatic relief can be obtained by washing the eyes with clean cold water. • Mast cell stabilizers drops • Antihistamine drops • Soothing agents
  • 35. CHEMICAL CONJUNCTIVITIS This is caused by exposure to an irritant chemical such as • acids, • tobacco • smoke, • snake venom, or the • sap of certain trees- particularly Euphorbia spp.
  • 36. PRESENTATION/RX • There is usually hx of chemical entering the eye • Patient has painful, watering, red eye • If exposure took place within the preceding few hours, it may be helpful to irrigate the conjunctival sac • Antibiotic drops should be given to prevent secondary infection