The document discusses diseases of the liver. It begins by describing the liver's location and functions, including producing bile to aid digestion and regulating biochemical reactions. It then discusses the liver's blood supply, biliary flow, synthesis, breakdown, detoxification, protein synthesis, and glycogen regulation. Key clinical diseases are then outlined, such as alcoholic liver disease, hepatotoxicity from drug overdoses, and hepatic failure. Guidelines for ICD-10-CM coding of various liver diseases are provided.

1. DISEASES OF LIVER

2. LIVER
• liver is a vital organ of vertebrates,In humans,
it is located in the upper right quadrant of
the abdomen, below the diaphragm.
• The liver is a gland It is an accessory digestive
gland and produces bile, an alkaline compound
which aids in digestion via
the emulsification of lipids.

3. • The liver's highly specialized tissue consisting of
mostly hepatocytes regulates a wide variety of
high-volume biochemical reactions, including
the synthesis and breakdown of small and
complex molecules, many of which are necessary
for normal vital functions.

4. PHYSIOLOGY
• Blood supply
• Biliary flow
• Synthesis
• Breakdown
• Detoxification
• Protein synthesis
• Regulation of glycogen

5. CLINICAL SIGNIFICANCE
• Alcoholic liver disease:- is a term that
encompasses the liver manifestations
of alcohol overconsumption, including fatty
liver, alcoholic hepatitis, and chronic
hepatitis with liver fibrosis or cirrhosis.
• Use additional code to identify alcohol abuse
and dependence(F10.-)

6. • Hepatotoxicity implies chemical-
driven liver damage.
• The liver plays a central role in transforming and
clearing chemicals and is susceptible to the toxicity
from these agents. Certain medicinal agents, when
taken in overdoses and sometimes even when
introduced within therapeutic ranges, may injure
the organ.
• Code first poisoning due to drug or toxin,if
applicable to identify drug(T36-T50 with 5 or 6
character 5)

7. • Hepatic failure is a loss of liver function that
occurs rapidly-in days or weeks.
• Cirrhosis of liver is defined as a scar tissue is
replaced with a normal tissue of liver is leads
abnormal function of the liver.

8. ICD-10-CM GUIDELINES
• Alcoholic liver disease-K70
• Toxic liver disease-K71
• Hepatic failure not else where classified-K72
• Chronic hepatitis,not elsewhere classified-K73
• Fibrosis and cirrhosis of liver-K74

9. • Other inflammatory liver diseases-K75
• Other diseases of liver-K76
• Liver disorders in diseases classified elsewhere-
K77
• Code first underlying diseases
• https://www.medesunglobal.com

10. THANK YOU