SlideShare a Scribd company logo
Discuss the specific properties of the 5 classes of Immunoglobulins and the specific component
parts that each have (i.e., J chain, SC protein, CDR regions, ITAM regions, complement
activation, allotype variation).
Solution
Generally there are 5 classes of immunoglobins, and they are IgG, IgM,IgA, IgD and IgE.
IgG
It is the major immunoglobin present in the serum almost about 75 % of immunoglobin in serum
is IgG. Its an important antibody in secondary immune response. It promotes opsonization and
fixes complement and also enhances phagocytosis.
IgM
It is the third most common immunoglobin in the serum. It is the first immunoglobin to be made
by the fetus. It has a pentameric structure. The pentamer has a J chain. Most capable of
complement fixation, agglutination. Present mainly on B cells and effective against viruses and
bacteria. IgM have about 60 CDR’s.
IgA
Secretory immunoglobin mainly present in tears, saliva, colostrum and helps in removal of
microbes from mucous membrane. Consist of 2 heavy chains and two light chains joined by a J
chain. It does not fix complement. Colostrum is having abundant IgA. SC protein is a part of
IgA.
IgD
Present in low levels in serum and found on B cell surface. Exist as monomers. Complement
binding is not done by IgD. The exact function of this class is still not known precisely.
IgE
Monomeric in nature and least amounts are present. Responsible for allergic reactions. Present in
skin and lungs. Do not fix complement. Effective against parasites in the body. Commonly
related to diseases like asthma.
CDR’s:
Except IgM all other antibodies have 12 CDR’s. Since IgM is a pentameric molecule it has about
60 CDR’s.
ITAM regions:
These are motifs present in the Fc receptors of immunoglobin molecule.
Allotype:
Allele of the antibody chains is termed as allotype.

More Related Content

Similar to Discuss the specific properties of the 5 classes of Immunoglobulins .pdf

ANTIBODY FINAL.pptx
ANTIBODY FINAL.pptxANTIBODY FINAL.pptx
ANTIBODY FINAL.pptx
Debasish Sahoo
 
Immunoglobulin classes
Immunoglobulin classesImmunoglobulin classes
Immunoglobulin classes
RenukaR17
 
Antibodies immunoglobulin
Antibodies immunoglobulinAntibodies immunoglobulin
Antibodies immunoglobulin
Dr.Dhananjay Singh
 
Antigen structure and immunogenicity
Antigen structure and immunogenicityAntigen structure and immunogenicity
Antigen structure and immunogenicity
Microbiology
 
Immunoglobulins (2)
Immunoglobulins (2)Immunoglobulins (2)
Immunoglobulins (2)
DrShagufta Akmal
 
Immunoglobins
Immunoglobins Immunoglobins
Immunoglobins
hephz
 
Immuology
ImmuologyImmuology
Immuology
AhmedRiyadh17
 
The usage of immunological reactions in diagnostics of infectious diseases.
The usage of immunological reactions in diagnostics of infectious diseases. The usage of immunological reactions in diagnostics of infectious diseases.
The usage of immunological reactions in diagnostics of infectious diseases.
Eneutron
 
Immunoglobulins, complement and immunodefeciency disorders
Immunoglobulins, complement and immunodefeciency disordersImmunoglobulins, complement and immunodefeciency disorders
Immunoglobulins, complement and immunodefeciency disorders
Krishna Vasudev
 
Humoral Immunity Lecture
Humoral Immunity LectureHumoral Immunity Lecture
Humoral Immunity Lecture
MD Specialclass
 
Immunoglobulins ppt.pptx
Immunoglobulins ppt.pptxImmunoglobulins ppt.pptx
Immunoglobulins ppt.pptx
MahendraKumar735541
 
Immunoglobuins & their functions
Immunoglobuins & their functionsImmunoglobuins & their functions
Immunoglobuins & their functions
Dr. Roshni Maurya
 
chapter 11 - DRBHAVIKA Antibody(Immunity).pptx
chapter 11 - DRBHAVIKA Antibody(Immunity).pptxchapter 11 - DRBHAVIKA Antibody(Immunity).pptx
chapter 11 - DRBHAVIKA Antibody(Immunity).pptx
DrBhavikapatel
 
Antibodies converted
Antibodies convertedAntibodies converted
Antibodies converted
Annumaurya
 
Antibodies
AntibodiesAntibodies
Antibodies
Safeena Majeed
 
immunoglobuinstheirfunctions-150920084551-lva1-app6892.pdf
immunoglobuinstheirfunctions-150920084551-lva1-app6892.pdfimmunoglobuinstheirfunctions-150920084551-lva1-app6892.pdf
immunoglobuinstheirfunctions-150920084551-lva1-app6892.pdf
OsmanHassan35
 
ANTIBODIES-IMMUNOGLOBULINS
ANTIBODIES-IMMUNOGLOBULINSANTIBODIES-IMMUNOGLOBULINS
ANTIBODIES-IMMUNOGLOBULINS
ILA HITHAISHI
 
5th immunoglobulins 2 oct 2014
5th immunoglobulins 2 oct 20145th immunoglobulins 2 oct 2014
5th immunoglobulins 2 oct 2014
the university of lahore
 
antibody types1.pdf
antibody types1.pdfantibody types1.pdf
antibody types1.pdf
Mohamed Alashram
 
5 types of Immunoglobulins
5 types of Immunoglobulins5 types of Immunoglobulins
5 types of Immunoglobulins
ziyiChen18
 

Similar to Discuss the specific properties of the 5 classes of Immunoglobulins .pdf (20)

ANTIBODY FINAL.pptx
ANTIBODY FINAL.pptxANTIBODY FINAL.pptx
ANTIBODY FINAL.pptx
 
Immunoglobulin classes
Immunoglobulin classesImmunoglobulin classes
Immunoglobulin classes
 
Antibodies immunoglobulin
Antibodies immunoglobulinAntibodies immunoglobulin
Antibodies immunoglobulin
 
Antigen structure and immunogenicity
Antigen structure and immunogenicityAntigen structure and immunogenicity
Antigen structure and immunogenicity
 
Immunoglobulins (2)
Immunoglobulins (2)Immunoglobulins (2)
Immunoglobulins (2)
 
Immunoglobins
Immunoglobins Immunoglobins
Immunoglobins
 
Immuology
ImmuologyImmuology
Immuology
 
The usage of immunological reactions in diagnostics of infectious diseases.
The usage of immunological reactions in diagnostics of infectious diseases. The usage of immunological reactions in diagnostics of infectious diseases.
The usage of immunological reactions in diagnostics of infectious diseases.
 
Immunoglobulins, complement and immunodefeciency disorders
Immunoglobulins, complement and immunodefeciency disordersImmunoglobulins, complement and immunodefeciency disorders
Immunoglobulins, complement and immunodefeciency disorders
 
Humoral Immunity Lecture
Humoral Immunity LectureHumoral Immunity Lecture
Humoral Immunity Lecture
 
Immunoglobulins ppt.pptx
Immunoglobulins ppt.pptxImmunoglobulins ppt.pptx
Immunoglobulins ppt.pptx
 
Immunoglobuins & their functions
Immunoglobuins & their functionsImmunoglobuins & their functions
Immunoglobuins & their functions
 
chapter 11 - DRBHAVIKA Antibody(Immunity).pptx
chapter 11 - DRBHAVIKA Antibody(Immunity).pptxchapter 11 - DRBHAVIKA Antibody(Immunity).pptx
chapter 11 - DRBHAVIKA Antibody(Immunity).pptx
 
Antibodies converted
Antibodies convertedAntibodies converted
Antibodies converted
 
Antibodies
AntibodiesAntibodies
Antibodies
 
immunoglobuinstheirfunctions-150920084551-lva1-app6892.pdf
immunoglobuinstheirfunctions-150920084551-lva1-app6892.pdfimmunoglobuinstheirfunctions-150920084551-lva1-app6892.pdf
immunoglobuinstheirfunctions-150920084551-lva1-app6892.pdf
 
ANTIBODIES-IMMUNOGLOBULINS
ANTIBODIES-IMMUNOGLOBULINSANTIBODIES-IMMUNOGLOBULINS
ANTIBODIES-IMMUNOGLOBULINS
 
5th immunoglobulins 2 oct 2014
5th immunoglobulins 2 oct 20145th immunoglobulins 2 oct 2014
5th immunoglobulins 2 oct 2014
 
antibody types1.pdf
antibody types1.pdfantibody types1.pdf
antibody types1.pdf
 
5 types of Immunoglobulins
5 types of Immunoglobulins5 types of Immunoglobulins
5 types of Immunoglobulins
 

More from solimankellymattwe60

What are the products of the secondary metabolism in plants Terpeno.pdf
What are the products of the secondary metabolism in plants  Terpeno.pdfWhat are the products of the secondary metabolism in plants  Terpeno.pdf
What are the products of the secondary metabolism in plants Terpeno.pdf
solimankellymattwe60
 
Which of the following is incorrect about emergent propertiesA. T.pdf
Which of the following is incorrect about emergent propertiesA. T.pdfWhich of the following is incorrect about emergent propertiesA. T.pdf
Which of the following is incorrect about emergent propertiesA. T.pdf
solimankellymattwe60
 
Which sensor i can use it for my robot when i dont want it to fil.pdf
Which sensor i can use it for my robot when i dont want it to fil.pdfWhich sensor i can use it for my robot when i dont want it to fil.pdf
Which sensor i can use it for my robot when i dont want it to fil.pdf
solimankellymattwe60
 
Why might firms consider issuing stock in foreign countries Why mig.pdf
Why might firms consider issuing stock in foreign countries Why mig.pdfWhy might firms consider issuing stock in foreign countries Why mig.pdf
Why might firms consider issuing stock in foreign countries Why mig.pdf
solimankellymattwe60
 
What were the Spanish soldiers who fought in the conquests in the Ne.pdf
What were the Spanish soldiers who fought in the conquests in the Ne.pdfWhat were the Spanish soldiers who fought in the conquests in the Ne.pdf
What were the Spanish soldiers who fought in the conquests in the Ne.pdf
solimankellymattwe60
 
What is forecasting Explain the different techniques of forecasting.pdf
What is forecasting Explain the different techniques of forecasting.pdfWhat is forecasting Explain the different techniques of forecasting.pdf
What is forecasting Explain the different techniques of forecasting.pdf
solimankellymattwe60
 
Ventura Capital is a financier who specializes in capitalizing start.pdf
Ventura Capital is a financier who specializes in capitalizing start.pdfVentura Capital is a financier who specializes in capitalizing start.pdf
Ventura Capital is a financier who specializes in capitalizing start.pdf
solimankellymattwe60
 
True or False1. A basidium is a cell of the Basidiomycota in whic.pdf
True or False1. A basidium is a cell of the Basidiomycota in whic.pdfTrue or False1. A basidium is a cell of the Basidiomycota in whic.pdf
True or False1. A basidium is a cell of the Basidiomycota in whic.pdf
solimankellymattwe60
 
The mitochondrial electron transport system (METS) and the photos.pdf
The mitochondrial electron transport system (METS) and the photos.pdfThe mitochondrial electron transport system (METS) and the photos.pdf
The mitochondrial electron transport system (METS) and the photos.pdf
solimankellymattwe60
 
The disclosure of a contingent liability in the footnotes and on t.pdf
The disclosure of a contingent liability in the footnotes and on t.pdfThe disclosure of a contingent liability in the footnotes and on t.pdf
The disclosure of a contingent liability in the footnotes and on t.pdf
solimankellymattwe60
 
The application architeture is design by the application developer a.pdf
The application architeture is design by the application developer a.pdfThe application architeture is design by the application developer a.pdf
The application architeture is design by the application developer a.pdf
solimankellymattwe60
 
Suppose a company’s ROE is 16. This company’s payout ratio is 40. .pdf
Suppose a company’s ROE is 16. This company’s payout ratio is 40. .pdfSuppose a company’s ROE is 16. This company’s payout ratio is 40. .pdf
Suppose a company’s ROE is 16. This company’s payout ratio is 40. .pdf
solimankellymattwe60
 
Some historians have referred to many of the self-proclaimed “Darwin.pdf
Some historians have referred to many of the self-proclaimed “Darwin.pdfSome historians have referred to many of the self-proclaimed “Darwin.pdf
Some historians have referred to many of the self-proclaimed “Darwin.pdf
solimankellymattwe60
 
Please research Meaningful Use. Prepare a brief report on its origin.pdf
Please research Meaningful Use. Prepare a brief report on its origin.pdfPlease research Meaningful Use. Prepare a brief report on its origin.pdf
Please research Meaningful Use. Prepare a brief report on its origin.pdf
solimankellymattwe60
 
Mention the major difference in the physical phenomena occurring rel.pdf
Mention the major difference in the physical phenomena occurring rel.pdfMention the major difference in the physical phenomena occurring rel.pdf
Mention the major difference in the physical phenomena occurring rel.pdf
solimankellymattwe60
 
My code is not matching up with the results.The output for the cod.pdf
My code is not matching up with the results.The output for the cod.pdfMy code is not matching up with the results.The output for the cod.pdf
My code is not matching up with the results.The output for the cod.pdf
solimankellymattwe60
 
Logical FallociesP1 All college students have pet monkeys.P2 J.pdf
Logical FallociesP1 All college students have pet monkeys.P2 J.pdfLogical FallociesP1 All college students have pet monkeys.P2 J.pdf
Logical FallociesP1 All college students have pet monkeys.P2 J.pdf
solimankellymattwe60
 
IP Security One problem with Internet protocol (IP) is that it has.pdf
IP Security One problem with Internet protocol (IP) is that it has.pdfIP Security One problem with Internet protocol (IP) is that it has.pdf
IP Security One problem with Internet protocol (IP) is that it has.pdf
solimankellymattwe60
 
Genmo CorporationOn the night of February 27, 2012, certain recor.pdf
Genmo CorporationOn the night of February 27, 2012, certain recor.pdfGenmo CorporationOn the night of February 27, 2012, certain recor.pdf
Genmo CorporationOn the night of February 27, 2012, certain recor.pdf
solimankellymattwe60
 
In the formula for determining a populations genotype frequencies, .pdf
In the formula for determining a populations genotype frequencies, .pdfIn the formula for determining a populations genotype frequencies, .pdf
In the formula for determining a populations genotype frequencies, .pdf
solimankellymattwe60
 

More from solimankellymattwe60 (20)

What are the products of the secondary metabolism in plants Terpeno.pdf
What are the products of the secondary metabolism in plants  Terpeno.pdfWhat are the products of the secondary metabolism in plants  Terpeno.pdf
What are the products of the secondary metabolism in plants Terpeno.pdf
 
Which of the following is incorrect about emergent propertiesA. T.pdf
Which of the following is incorrect about emergent propertiesA. T.pdfWhich of the following is incorrect about emergent propertiesA. T.pdf
Which of the following is incorrect about emergent propertiesA. T.pdf
 
Which sensor i can use it for my robot when i dont want it to fil.pdf
Which sensor i can use it for my robot when i dont want it to fil.pdfWhich sensor i can use it for my robot when i dont want it to fil.pdf
Which sensor i can use it for my robot when i dont want it to fil.pdf
 
Why might firms consider issuing stock in foreign countries Why mig.pdf
Why might firms consider issuing stock in foreign countries Why mig.pdfWhy might firms consider issuing stock in foreign countries Why mig.pdf
Why might firms consider issuing stock in foreign countries Why mig.pdf
 
What were the Spanish soldiers who fought in the conquests in the Ne.pdf
What were the Spanish soldiers who fought in the conquests in the Ne.pdfWhat were the Spanish soldiers who fought in the conquests in the Ne.pdf
What were the Spanish soldiers who fought in the conquests in the Ne.pdf
 
What is forecasting Explain the different techniques of forecasting.pdf
What is forecasting Explain the different techniques of forecasting.pdfWhat is forecasting Explain the different techniques of forecasting.pdf
What is forecasting Explain the different techniques of forecasting.pdf
 
Ventura Capital is a financier who specializes in capitalizing start.pdf
Ventura Capital is a financier who specializes in capitalizing start.pdfVentura Capital is a financier who specializes in capitalizing start.pdf
Ventura Capital is a financier who specializes in capitalizing start.pdf
 
True or False1. A basidium is a cell of the Basidiomycota in whic.pdf
True or False1. A basidium is a cell of the Basidiomycota in whic.pdfTrue or False1. A basidium is a cell of the Basidiomycota in whic.pdf
True or False1. A basidium is a cell of the Basidiomycota in whic.pdf
 
The mitochondrial electron transport system (METS) and the photos.pdf
The mitochondrial electron transport system (METS) and the photos.pdfThe mitochondrial electron transport system (METS) and the photos.pdf
The mitochondrial electron transport system (METS) and the photos.pdf
 
The disclosure of a contingent liability in the footnotes and on t.pdf
The disclosure of a contingent liability in the footnotes and on t.pdfThe disclosure of a contingent liability in the footnotes and on t.pdf
The disclosure of a contingent liability in the footnotes and on t.pdf
 
The application architeture is design by the application developer a.pdf
The application architeture is design by the application developer a.pdfThe application architeture is design by the application developer a.pdf
The application architeture is design by the application developer a.pdf
 
Suppose a company’s ROE is 16. This company’s payout ratio is 40. .pdf
Suppose a company’s ROE is 16. This company’s payout ratio is 40. .pdfSuppose a company’s ROE is 16. This company’s payout ratio is 40. .pdf
Suppose a company’s ROE is 16. This company’s payout ratio is 40. .pdf
 
Some historians have referred to many of the self-proclaimed “Darwin.pdf
Some historians have referred to many of the self-proclaimed “Darwin.pdfSome historians have referred to many of the self-proclaimed “Darwin.pdf
Some historians have referred to many of the self-proclaimed “Darwin.pdf
 
Please research Meaningful Use. Prepare a brief report on its origin.pdf
Please research Meaningful Use. Prepare a brief report on its origin.pdfPlease research Meaningful Use. Prepare a brief report on its origin.pdf
Please research Meaningful Use. Prepare a brief report on its origin.pdf
 
Mention the major difference in the physical phenomena occurring rel.pdf
Mention the major difference in the physical phenomena occurring rel.pdfMention the major difference in the physical phenomena occurring rel.pdf
Mention the major difference in the physical phenomena occurring rel.pdf
 
My code is not matching up with the results.The output for the cod.pdf
My code is not matching up with the results.The output for the cod.pdfMy code is not matching up with the results.The output for the cod.pdf
My code is not matching up with the results.The output for the cod.pdf
 
Logical FallociesP1 All college students have pet monkeys.P2 J.pdf
Logical FallociesP1 All college students have pet monkeys.P2 J.pdfLogical FallociesP1 All college students have pet monkeys.P2 J.pdf
Logical FallociesP1 All college students have pet monkeys.P2 J.pdf
 
IP Security One problem with Internet protocol (IP) is that it has.pdf
IP Security One problem with Internet protocol (IP) is that it has.pdfIP Security One problem with Internet protocol (IP) is that it has.pdf
IP Security One problem with Internet protocol (IP) is that it has.pdf
 
Genmo CorporationOn the night of February 27, 2012, certain recor.pdf
Genmo CorporationOn the night of February 27, 2012, certain recor.pdfGenmo CorporationOn the night of February 27, 2012, certain recor.pdf
Genmo CorporationOn the night of February 27, 2012, certain recor.pdf
 
In the formula for determining a populations genotype frequencies, .pdf
In the formula for determining a populations genotype frequencies, .pdfIn the formula for determining a populations genotype frequencies, .pdf
In the formula for determining a populations genotype frequencies, .pdf
 

Recently uploaded

C1 Rubenstein AP HuG xxxxxxxxxxxxxx.pptx
C1 Rubenstein AP HuG xxxxxxxxxxxxxx.pptxC1 Rubenstein AP HuG xxxxxxxxxxxxxx.pptx
C1 Rubenstein AP HuG xxxxxxxxxxxxxx.pptx
mulvey2
 
Walmart Business+ and Spark Good for Nonprofits.pdf
Walmart Business+ and Spark Good for Nonprofits.pdfWalmart Business+ and Spark Good for Nonprofits.pdf
Walmart Business+ and Spark Good for Nonprofits.pdf
TechSoup
 
Advanced Java[Extra Concepts, Not Difficult].docx
Advanced Java[Extra Concepts, Not Difficult].docxAdvanced Java[Extra Concepts, Not Difficult].docx
Advanced Java[Extra Concepts, Not Difficult].docx
adhitya5119
 
DRUGS AND ITS classification slide share
DRUGS AND ITS classification slide shareDRUGS AND ITS classification slide share
DRUGS AND ITS classification slide share
taiba qazi
 
Digital Artefact 1 - Tiny Home Environmental Design
Digital Artefact 1 - Tiny Home Environmental DesignDigital Artefact 1 - Tiny Home Environmental Design
Digital Artefact 1 - Tiny Home Environmental Design
amberjdewit93
 
Digital Artifact 1 - 10VCD Environments Unit
Digital Artifact 1 - 10VCD Environments UnitDigital Artifact 1 - 10VCD Environments Unit
Digital Artifact 1 - 10VCD Environments Unit
chanes7
 
Smart-Money for SMC traders good time and ICT
Smart-Money for SMC traders good time and ICTSmart-Money for SMC traders good time and ICT
Smart-Money for SMC traders good time and ICT
simonomuemu
 
The simplified electron and muon model, Oscillating Spacetime: The Foundation...
The simplified electron and muon model, Oscillating Spacetime: The Foundation...The simplified electron and muon model, Oscillating Spacetime: The Foundation...
The simplified electron and muon model, Oscillating Spacetime: The Foundation...
RitikBhardwaj56
 
clinical examination of hip joint (1).pdf
clinical examination of hip joint (1).pdfclinical examination of hip joint (1).pdf
clinical examination of hip joint (1).pdf
Priyankaranawat4
 
How to Manage Your Lost Opportunities in Odoo 17 CRM
How to Manage Your Lost Opportunities in Odoo 17 CRMHow to Manage Your Lost Opportunities in Odoo 17 CRM
How to Manage Your Lost Opportunities in Odoo 17 CRM
Celine George
 
South African Journal of Science: Writing with integrity workshop (2024)
South African Journal of Science: Writing with integrity workshop (2024)South African Journal of Science: Writing with integrity workshop (2024)
South African Journal of Science: Writing with integrity workshop (2024)
Academy of Science of South Africa
 
Chapter 4 - Islamic Financial Institutions in Malaysia.pptx
Chapter 4 - Islamic Financial Institutions in Malaysia.pptxChapter 4 - Islamic Financial Institutions in Malaysia.pptx
Chapter 4 - Islamic Financial Institutions in Malaysia.pptx
Mohd Adib Abd Muin, Senior Lecturer at Universiti Utara Malaysia
 
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...
GeorgeMilliken2
 
Film vocab for eal 3 students: Australia the movie
Film vocab for eal 3 students: Australia the movieFilm vocab for eal 3 students: Australia the movie
Film vocab for eal 3 students: Australia the movie
Nicholas Montgomery
 
Life upper-Intermediate B2 Workbook for student
Life upper-Intermediate B2 Workbook for studentLife upper-Intermediate B2 Workbook for student
Life upper-Intermediate B2 Workbook for student
NgcHiNguyn25
 
ANATOMY AND BIOMECHANICS OF HIP JOINT.pdf
ANATOMY AND BIOMECHANICS OF HIP JOINT.pdfANATOMY AND BIOMECHANICS OF HIP JOINT.pdf
ANATOMY AND BIOMECHANICS OF HIP JOINT.pdf
Priyankaranawat4
 
A Independência da América Espanhola LAPBOOK.pdf
A Independência da América Espanhola LAPBOOK.pdfA Independência da América Espanhola LAPBOOK.pdf
A Independência da América Espanhola LAPBOOK.pdf
Jean Carlos Nunes Paixão
 
BBR 2024 Summer Sessions Interview Training
BBR  2024 Summer Sessions Interview TrainingBBR  2024 Summer Sessions Interview Training
BBR 2024 Summer Sessions Interview Training
Katrina Pritchard
 
ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...
ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...
ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...
PECB
 
Executive Directors Chat Leveraging AI for Diversity, Equity, and Inclusion
Executive Directors Chat  Leveraging AI for Diversity, Equity, and InclusionExecutive Directors Chat  Leveraging AI for Diversity, Equity, and Inclusion
Executive Directors Chat Leveraging AI for Diversity, Equity, and Inclusion
TechSoup
 

Recently uploaded (20)

C1 Rubenstein AP HuG xxxxxxxxxxxxxx.pptx
C1 Rubenstein AP HuG xxxxxxxxxxxxxx.pptxC1 Rubenstein AP HuG xxxxxxxxxxxxxx.pptx
C1 Rubenstein AP HuG xxxxxxxxxxxxxx.pptx
 
Walmart Business+ and Spark Good for Nonprofits.pdf
Walmart Business+ and Spark Good for Nonprofits.pdfWalmart Business+ and Spark Good for Nonprofits.pdf
Walmart Business+ and Spark Good for Nonprofits.pdf
 
Advanced Java[Extra Concepts, Not Difficult].docx
Advanced Java[Extra Concepts, Not Difficult].docxAdvanced Java[Extra Concepts, Not Difficult].docx
Advanced Java[Extra Concepts, Not Difficult].docx
 
DRUGS AND ITS classification slide share
DRUGS AND ITS classification slide shareDRUGS AND ITS classification slide share
DRUGS AND ITS classification slide share
 
Digital Artefact 1 - Tiny Home Environmental Design
Digital Artefact 1 - Tiny Home Environmental DesignDigital Artefact 1 - Tiny Home Environmental Design
Digital Artefact 1 - Tiny Home Environmental Design
 
Digital Artifact 1 - 10VCD Environments Unit
Digital Artifact 1 - 10VCD Environments UnitDigital Artifact 1 - 10VCD Environments Unit
Digital Artifact 1 - 10VCD Environments Unit
 
Smart-Money for SMC traders good time and ICT
Smart-Money for SMC traders good time and ICTSmart-Money for SMC traders good time and ICT
Smart-Money for SMC traders good time and ICT
 
The simplified electron and muon model, Oscillating Spacetime: The Foundation...
The simplified electron and muon model, Oscillating Spacetime: The Foundation...The simplified electron and muon model, Oscillating Spacetime: The Foundation...
The simplified electron and muon model, Oscillating Spacetime: The Foundation...
 
clinical examination of hip joint (1).pdf
clinical examination of hip joint (1).pdfclinical examination of hip joint (1).pdf
clinical examination of hip joint (1).pdf
 
How to Manage Your Lost Opportunities in Odoo 17 CRM
How to Manage Your Lost Opportunities in Odoo 17 CRMHow to Manage Your Lost Opportunities in Odoo 17 CRM
How to Manage Your Lost Opportunities in Odoo 17 CRM
 
South African Journal of Science: Writing with integrity workshop (2024)
South African Journal of Science: Writing with integrity workshop (2024)South African Journal of Science: Writing with integrity workshop (2024)
South African Journal of Science: Writing with integrity workshop (2024)
 
Chapter 4 - Islamic Financial Institutions in Malaysia.pptx
Chapter 4 - Islamic Financial Institutions in Malaysia.pptxChapter 4 - Islamic Financial Institutions in Malaysia.pptx
Chapter 4 - Islamic Financial Institutions in Malaysia.pptx
 
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...
What is Digital Literacy? A guest blog from Andy McLaughlin, University of Ab...
 
Film vocab for eal 3 students: Australia the movie
Film vocab for eal 3 students: Australia the movieFilm vocab for eal 3 students: Australia the movie
Film vocab for eal 3 students: Australia the movie
 
Life upper-Intermediate B2 Workbook for student
Life upper-Intermediate B2 Workbook for studentLife upper-Intermediate B2 Workbook for student
Life upper-Intermediate B2 Workbook for student
 
ANATOMY AND BIOMECHANICS OF HIP JOINT.pdf
ANATOMY AND BIOMECHANICS OF HIP JOINT.pdfANATOMY AND BIOMECHANICS OF HIP JOINT.pdf
ANATOMY AND BIOMECHANICS OF HIP JOINT.pdf
 
A Independência da América Espanhola LAPBOOK.pdf
A Independência da América Espanhola LAPBOOK.pdfA Independência da América Espanhola LAPBOOK.pdf
A Independência da América Espanhola LAPBOOK.pdf
 
BBR 2024 Summer Sessions Interview Training
BBR  2024 Summer Sessions Interview TrainingBBR  2024 Summer Sessions Interview Training
BBR 2024 Summer Sessions Interview Training
 
ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...
ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...
ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...
 
Executive Directors Chat Leveraging AI for Diversity, Equity, and Inclusion
Executive Directors Chat  Leveraging AI for Diversity, Equity, and InclusionExecutive Directors Chat  Leveraging AI for Diversity, Equity, and Inclusion
Executive Directors Chat Leveraging AI for Diversity, Equity, and Inclusion
 

Discuss the specific properties of the 5 classes of Immunoglobulins .pdf

  • 1. Discuss the specific properties of the 5 classes of Immunoglobulins and the specific component parts that each have (i.e., J chain, SC protein, CDR regions, ITAM regions, complement activation, allotype variation). Solution Generally there are 5 classes of immunoglobins, and they are IgG, IgM,IgA, IgD and IgE. IgG It is the major immunoglobin present in the serum almost about 75 % of immunoglobin in serum is IgG. Its an important antibody in secondary immune response. It promotes opsonization and fixes complement and also enhances phagocytosis. IgM It is the third most common immunoglobin in the serum. It is the first immunoglobin to be made by the fetus. It has a pentameric structure. The pentamer has a J chain. Most capable of complement fixation, agglutination. Present mainly on B cells and effective against viruses and bacteria. IgM have about 60 CDR’s. IgA Secretory immunoglobin mainly present in tears, saliva, colostrum and helps in removal of microbes from mucous membrane. Consist of 2 heavy chains and two light chains joined by a J chain. It does not fix complement. Colostrum is having abundant IgA. SC protein is a part of IgA. IgD Present in low levels in serum and found on B cell surface. Exist as monomers. Complement binding is not done by IgD. The exact function of this class is still not known precisely. IgE Monomeric in nature and least amounts are present. Responsible for allergic reactions. Present in skin and lungs. Do not fix complement. Effective against parasites in the body. Commonly related to diseases like asthma. CDR’s: Except IgM all other antibodies have 12 CDR’s. Since IgM is a pentameric molecule it has about 60 CDR’s. ITAM regions: These are motifs present in the Fc receptors of immunoglobin molecule. Allotype: Allele of the antibody chains is termed as allotype.