The document discusses the applications of dexmedetomidine in pediatric procedural sedation. It provides background on dexmedetomidine's pharmacology and mechanisms of action. It then reviews clinical experience using dexmedetomidine for sedation in the pediatric intensive care unit and for procedural sedation, finding it effective with minimal respiratory depression and short recovery times. Studies show dexmedetomidine is effective for sedation during procedures like MRI and CT scans in children.