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Developing your SR search strategy
SARAH YOUNG
HEALTH SCIENCE AND POLICY LIBRARIAN
Today’s presentation
Access to library resources
Developing your search strategy
Reporting of ongoing unpublished trials
Using library services
A guide to library resources
http://guides.library.cornell.edu/WHO
Access to resources: The catalog
https://www.library.cornell.edu/
Access to full text
Access to full text: Don’t give up!
Developing your search strategy
Example: Malnutrition
Use both indexing terms and free-text
“Malnutrition"[MeSH] OR “malnutrition” OR
“undernutrition" OR “under-nutrition” OR “nutritional
deficiency” OR “undernourishment”
Why use free-text AND indexing terms?
Indexing quality varies by database
Some articles have not yet been indexed
No abstract included
Non-English material
Standardized Index Terms
Standardized Index Terms
HIV
"human immuno-deficiency virus" n=199
"HIV"[Mesh] n=80480
Combine standardized terms with
natural language
HIV
"human immuno-deficiency virus" n=199
"HIV"[Mesh] n=80480
"HIV"[Mesh] OR "human immuno-deficiency virus"
n=80640
We added 160 articles by including the free-text term
in the MeSH term search
Search strategy with harvested terms
HIV Infections[MeSH] OR HIV[MeSH] OR hiv[tw] OR
hiv-1[tw] OR hiv-2[tw] OR human immunodeficiency
virus[tw] OR human immunedeficiency virus[tw] OR
human immuno-deficiency virus[tw] OR human
immune-deficiency virus[tw]
n= 315017
Term harvesting
Synonyms in standard index entries
Titles and abstracts of key articles
Dictionaries and Thesauri
Example: preterm infant
Putting together a search strategy
High sensitivity (low precision)
Minimize bias
Reproducible (documentation)
Putting together a search strategy
Example:
Micronutrient supplementation in pregnant women with HIV infection
The Cochrane Collaboration
Siegfried N, Irlam JH, Visser ME, and Rollins NN
2012
Putting together a search strategy
Objective:
To assess whether micronutrient supplements are
effective and safe in reducing mortality and morbidity in
pregnant women with HIV infection.
HIV
Type of study: RCT
Micronutrients
Micronutrients (cont.)
Micronutrients (combined)
Final (combined)
Type of study: RCT
Search
tips:
Use the
syntax
appropriate
to the
database
Search
tips:
Use the
syntax
appropriate
to the
database
Identify text
terms
Term harvest
for synonyms
Control for spelling
variation and use
truncation
Identify indexing
terms
Decide to
explode or focus
indexing terms
Combine all
search terms
logically
Customize syntax
for other
databases
Perform test
searches
Perform test
searches
Choosing databases
Choosing databases
Searched for reports of maternal mortality and morbidity
across various study designs
MEDLINE, Popline, EMBASE, CINAHL, CAB Abstracts, Econlit,
Sociofile, LILACS, BIOSIS and PAIS International
2580 citations included
Choosing databases
62
44
17
12
0
20
40
60
80
100
MEDLINE EMBASE BIOSIS POPLINE
Percent of Total Citations Identified
A guide to library resources
http://guides.library.cornell.edu/WHO
Outside of the published literature
Publication bias
Other sources: Unpublished clinical trials
WHO International Clinical Trials Registry Platform (ICTRP)
http://www.who.int/ictrp/en/
metaRegister of Controlled Trials (mRCT)
http://www.controlled-trials.com/mrct/
Other sources: Grey Literature
“…literature that is not formally published in
sources such as books or journal articles.”
Cochrane Handbook for Systematic Reviews of Interventions
Other sources: Grey Literature
"That which is produced on all levels of
government, academics, business and industry
in print and electronic formats, but which is not
controlled by commercial publishers.“
The Fourth International Conference on Grey Literature, Washington, DC
A guide to library resources
http://guides.library.cornell.edu/WHO
Finding Mann Library
Room to work
Available library services
Access to full text
Search strategy development
Using the databases
Citation management
Questions about Research4Life
Help with your research
sy493@cornell.edu
Office hours:
2-4 pm (except tomorrow)
Services and Collections offices, 1st floor of Mann
References
Betran, A.P. et al. (2005). “Effectiveness of different databases in identifying studies for
systematic reviews: experience from the WHO systematic review of maternal morbidity and
mortality”. BMC Medical Research Methodology, 5:6.
Fowler, S. (2013). “Library Resources for Systematic Reviews”. Presentation available from
http://www.slideshare.net/referencegirl/sys-revs-colditz.
Higgins, J.P.T. and Green, S. (eds.) (2011). Cochrane Handbook for Systematic Reviews of
Interventions, Version 5.1.0, available from http://handbook.cochrane.org/.
Siegfried, N. et al. (2012). “Micronutrient supplementation in pregnant women with HIV
infection (Review)”. The Cochrane Library, Issue 3.

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June 2024 Oncology Cartoons By Dr Kanhu Charan Patro
 

Developing a search strategy for your systematic review

  • 1. Developing your SR search strategy SARAH YOUNG HEALTH SCIENCE AND POLICY LIBRARIAN
  • 2. Today’s presentation Access to library resources Developing your search strategy Reporting of ongoing unpublished trials Using library services
  • 3. A guide to library resources http://guides.library.cornell.edu/WHO
  • 4. Access to resources: The catalog https://www.library.cornell.edu/
  • 6. Access to full text: Don’t give up!
  • 7. Developing your search strategy Example: Malnutrition Use both indexing terms and free-text “Malnutrition"[MeSH] OR “malnutrition” OR “undernutrition" OR “under-nutrition” OR “nutritional deficiency” OR “undernourishment”
  • 8. Why use free-text AND indexing terms? Indexing quality varies by database Some articles have not yet been indexed No abstract included Non-English material
  • 10. Standardized Index Terms HIV "human immuno-deficiency virus" n=199 "HIV"[Mesh] n=80480
  • 11. Combine standardized terms with natural language HIV "human immuno-deficiency virus" n=199 "HIV"[Mesh] n=80480 "HIV"[Mesh] OR "human immuno-deficiency virus" n=80640 We added 160 articles by including the free-text term in the MeSH term search
  • 12. Search strategy with harvested terms HIV Infections[MeSH] OR HIV[MeSH] OR hiv[tw] OR hiv-1[tw] OR hiv-2[tw] OR human immunodeficiency virus[tw] OR human immunedeficiency virus[tw] OR human immuno-deficiency virus[tw] OR human immune-deficiency virus[tw] n= 315017
  • 13. Term harvesting Synonyms in standard index entries Titles and abstracts of key articles Dictionaries and Thesauri
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  • 20. Putting together a search strategy High sensitivity (low precision) Minimize bias Reproducible (documentation)
  • 21. Putting together a search strategy Example: Micronutrient supplementation in pregnant women with HIV infection The Cochrane Collaboration Siegfried N, Irlam JH, Visser ME, and Rollins NN 2012
  • 22. Putting together a search strategy Objective: To assess whether micronutrient supplements are effective and safe in reducing mortality and morbidity in pregnant women with HIV infection.
  • 23. HIV
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  • 33. Identify text terms Term harvest for synonyms Control for spelling variation and use truncation Identify indexing terms Decide to explode or focus indexing terms Combine all search terms logically Customize syntax for other databases Perform test searches Perform test searches
  • 35. Choosing databases Searched for reports of maternal mortality and morbidity across various study designs MEDLINE, Popline, EMBASE, CINAHL, CAB Abstracts, Econlit, Sociofile, LILACS, BIOSIS and PAIS International 2580 citations included
  • 36. Choosing databases 62 44 17 12 0 20 40 60 80 100 MEDLINE EMBASE BIOSIS POPLINE Percent of Total Citations Identified
  • 37. A guide to library resources http://guides.library.cornell.edu/WHO
  • 38. Outside of the published literature Publication bias
  • 39. Other sources: Unpublished clinical trials WHO International Clinical Trials Registry Platform (ICTRP) http://www.who.int/ictrp/en/ metaRegister of Controlled Trials (mRCT) http://www.controlled-trials.com/mrct/
  • 40. Other sources: Grey Literature “…literature that is not formally published in sources such as books or journal articles.” Cochrane Handbook for Systematic Reviews of Interventions
  • 41. Other sources: Grey Literature "That which is produced on all levels of government, academics, business and industry in print and electronic formats, but which is not controlled by commercial publishers.“ The Fourth International Conference on Grey Literature, Washington, DC
  • 42. A guide to library resources http://guides.library.cornell.edu/WHO
  • 45. Available library services Access to full text Search strategy development Using the databases Citation management Questions about Research4Life
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  • 47. Help with your research sy493@cornell.edu Office hours: 2-4 pm (except tomorrow) Services and Collections offices, 1st floor of Mann
  • 48. References Betran, A.P. et al. (2005). “Effectiveness of different databases in identifying studies for systematic reviews: experience from the WHO systematic review of maternal morbidity and mortality”. BMC Medical Research Methodology, 5:6. Fowler, S. (2013). “Library Resources for Systematic Reviews”. Presentation available from http://www.slideshare.net/referencegirl/sys-revs-colditz. Higgins, J.P.T. and Green, S. (eds.) (2011). Cochrane Handbook for Systematic Reviews of Interventions, Version 5.1.0, available from http://handbook.cochrane.org/. Siegfried, N. et al. (2012). “Micronutrient supplementation in pregnant women with HIV infection (Review)”. The Cochrane Library, Issue 3.