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Death
1.
2. Points to be discussed are
What is death
Types of death
Brain death
3. DEATH
Tenatology is the study of all aspects of death
Historically death was considerd as spontaneous
stoppage of heart & lung function
New concept is of brain death, irreversible loss of
cerebral function
According to registration of births &deaths act,death is
the permanent disappearance all evidences of life at
any time after birth
5. SOMATIC DEATH
It is the complete and irreversible stoppage of
circulation, respiration and brain functions
It is important in resuscitation and organ
transplantation
As long as circulation of oxygenated blood is
maintained to brain stem, life exists
A person who cannot survive upon withdrawal of
artificial maintenance is dead
6. MOLECULAR DEATH
Death of cells & tissues individually
Takes place usually one to two hours after stoppage of
vital functions
Individual cell live on their residual oxygen for variable
time after circulation stopped
Nervous tissues die rapidly
Vital centers of brain loss in about five minutes
Muscles live up to one to two hours
7. ANOXIA
According to Gordon stoppage of vital functions
depends upon tissue anoxia
Anoxia means lack of oxygen
1.Anoxic anoxia
2.Anaemic anoxia
3.Stagnant anoxia
4.Histotoxic anoxia
8. Anoxic anoxia
Oxygen cannot reach blood, because lack of
oxygen in lungs
occurs
a)from contaminated atmosphere
b)From mechanical interference with passage
of air into or down the respiratory tract
Eg.smothering,choking,hanging or exposure to
fumes wells and tanks
9. Anaemic anoxia
Oxygen carrying capacity reduced
eg: acute massive haemorrhages,poisoning by carbon
monoxide, chlorates,nitrates,coaltar derivatives
Stagnant anoxia
Impaired circulation results in a reduction of
oxygen delivery to tissues eg:heart failure,embolism
and shock
10. Histotoxic anoxia
Enzymatic processes by which oxygen in blood
is used by the tissues are blocked
Eg: Acute cyanide poisoning
11. BRAIN DEATH
3 Types
1.cortical/cerebral death
2.Brain stem death
3.Whole brain death
12. BRAIN STEM DEATH
Here cerebrum intact
Loss of vital centers control respiration,
Loss of ascending reticular activating system that
sustain consciousness
Person become irreversibly comatose& incapable of
spontaneous breathing
Can be produced by raised intracranial pressure,
cerebral edema,intracranal hemorrhages
13. CORTICAL DEATH
Here brain stem intact
Respiration continues
Total loss of power of perception by senses
Deep coma is produced by cerebral hypoxia, toxic
conditions or brain injury
14. WHOLE BRAIN DEATH
Permanent cessation of functions of cerebrum
cerebellum & brain stem
15. CRITERIA FOR DETERMINING BRAIN
DEATH
Philadelphia protocol
Minnesota criteria
Harvard criteria
16. PHILADELPHIA PROTOCOL
Determined on basis of
Lack of responsiveness to internal and external
environment
Absence of spontaneous breathing movements for 3
minutes, in absence of hypocarbia
No muscular movements with generalized flaccidity
No reflexes and responses
Falling arterial pressure without support by drugs or other
means
Isoelectric EEG recorded spontaneously and during tactile
& auditory stimulation
17. MINNESOTA CRITERIA
Known but irreperable intracranial tension
No spontaneous movements
Apnoea
Absence of brain stem reflexes
All findings remain unchanged for at least 12 hours