Cerebrospinal fluid (CSF) circulates through the brain, spinal cord, and subarachnoid space. It is formed by the choroid plexus in the ventricles and provides protection, buoyancy, waste excretion, and regulates cranial volume. CSF is clear, colorless, and alkaline with a specific gravity of 1.005. It contains more sodium than potassium and some lymphocytes. CSF is absorbed by the arachnoid villi into dural sinuses and spinal veins and is produced and absorbed at a rate of around 500 ml per day.

1. Cerebrospinal Fluid
• Clear,colorless,transparent fluid
• Circulates through cavity of
-Brain,Subarachnoid space,Central canal of spinal cord
• Belongs to ECF

2. Functions of CSF
• Protection
• Buoyancy
• Excretion of waste products
• Regulation of cranial content volume

3. PROPERTIES
• VOLUME-150 ML
• RATE OF FORMATION-0.3 ml/min
• SPECIFIC GRAVITY:1.005
• REACTION:ALKALINE

4. COMPOSITION

5. • CONTAINS MORE OF SODIUMTHAN K+
• SOME LYMPHOCYTES

6. FORMATION OF CSF
• FORMED BY CHOROID PLEXUS SITUATED WITHINVENTRICLES
• CHOROID PLEXUS:Tuft of capillary projections present inside ventricles and
covered by piamater and ependymal covering
• Large amount of CSF is formed in the lateral ventricles

7. CIRCULATION OF CSF

8. ABSORPTION OF CSF
• By Arachnoid villi into dural sinuses and spinal veins
• Small amount is absorbed along perineural spaces into cervical lymphatics
and into perivascular spaces
• Normally 500 ml formed and absorbed daily

9. Collection of CSF
• LUMBAR PUNCTURE
• CISTERNAL PUNCTURE

10. APPLIED ANATOMY
• MENINGITIS
• HYDROCEPHALUS

13. MENINGITIS

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