Khoury CK (2019) “Crop Wild Relatives of North America: The Way Forward for Conservation and Use” Crop Wild Relatives of the Desert Borderlands: A Celebration of Diversity and a Call to Action, 13-15 January 2019, Tucson, AZ, USA.
Conservation and Use of the North American Plant Cornucopia: The Way ForwardCWRofUS
Khoury CK, Greene SL, Williams KA, Kantar M, and Marek L (2018) “Conservation and Use of the North American Plant Cornucopia: The Way Forward”. Symposium - Crop Wild Relatives and Genetic Resources for Interesting Traits, American Society of Agronomy and Crop Science Society of America Annual Meetings, 4-7 November 2018, Baltimore, USA
Building a Road Map for North American Crop Wild RelativesCWRofUS
Khoury CK, Greene SL, Moreau T, Krishnan S, Miller A (2019) “Building a Road Map for North American Crop Wild Relatives” Crop Wild Relatives: Developing a Roadmap to Shared Destinations Session, Celebrating Crop Diversity: Connecting Agriculture, Public Gardens, and Science, 2-4 April 2019, Des Moines, USA.
Distributions and collecting priorities for crop wild relatives in the United...CWRofUS
Our native crop wild relatives have proved useful as genetic resources in breeding more productive, nutritious, and resilient crops. Their utilization is expected only to increase with better information on the species and improving breeding tools, but may well be constrained by their limited representation in seedbanks and the ongoing loss of wild populations due to habitat modification, invasive species, climate change and other impacts. An urgent collecting effort for native crop genetic resources is therefore warranted. We present foundational information needed to guide this effort. An inventory of U.S. crop wild relatives has prioritized taxa related to a broad range of important food, forage and feed, medicinal, ornamental, and industrial crops. Utilizing occurrence data gathered from herbaria and genebanks, resulting potential distribution models are enabling the identification of hotspots of taxonomic diversity of wild relatives in the country, and a ‘gap analysis’ methodology is facilitating efforts to identify those taxa and geographic areas of particular conservation concern. Results indicate that a broad range of wild relative diversity remains to be collected, and that considerable high priority taxa are distributed in areas without long-term habitat protection.
CWR US Presentation ASA/CSSA/SSSA Tampa 2013 CWRofUS
Presentation of gap analysis results for Priority 1A CWR in the United States, given at the annual international ASA/CSSA/SSSA meeting, November 3-6, Tampa, Florida
Conservation Priorities for Tree Crop Wild Relatives in the United StatesCWRofUS
Presentation on conservation priorities of tree crop wild relatives of the U.S., given at the Gene Conservation of Tree Species – Banking on the Future Conference, 16-19 May 2016 in Chicago, USA
Conservation and Use of the North American Plant Cornucopia: The Way ForwardCWRofUS
Khoury CK, Greene SL, Williams KA, Kantar M, and Marek L (2018) “Conservation and Use of the North American Plant Cornucopia: The Way Forward”. Symposium - Crop Wild Relatives and Genetic Resources for Interesting Traits, American Society of Agronomy and Crop Science Society of America Annual Meetings, 4-7 November 2018, Baltimore, USA
Building a Road Map for North American Crop Wild RelativesCWRofUS
Khoury CK, Greene SL, Moreau T, Krishnan S, Miller A (2019) “Building a Road Map for North American Crop Wild Relatives” Crop Wild Relatives: Developing a Roadmap to Shared Destinations Session, Celebrating Crop Diversity: Connecting Agriculture, Public Gardens, and Science, 2-4 April 2019, Des Moines, USA.
Distributions and collecting priorities for crop wild relatives in the United...CWRofUS
Our native crop wild relatives have proved useful as genetic resources in breeding more productive, nutritious, and resilient crops. Their utilization is expected only to increase with better information on the species and improving breeding tools, but may well be constrained by their limited representation in seedbanks and the ongoing loss of wild populations due to habitat modification, invasive species, climate change and other impacts. An urgent collecting effort for native crop genetic resources is therefore warranted. We present foundational information needed to guide this effort. An inventory of U.S. crop wild relatives has prioritized taxa related to a broad range of important food, forage and feed, medicinal, ornamental, and industrial crops. Utilizing occurrence data gathered from herbaria and genebanks, resulting potential distribution models are enabling the identification of hotspots of taxonomic diversity of wild relatives in the country, and a ‘gap analysis’ methodology is facilitating efforts to identify those taxa and geographic areas of particular conservation concern. Results indicate that a broad range of wild relative diversity remains to be collected, and that considerable high priority taxa are distributed in areas without long-term habitat protection.
CWR US Presentation ASA/CSSA/SSSA Tampa 2013 CWRofUS
Presentation of gap analysis results for Priority 1A CWR in the United States, given at the annual international ASA/CSSA/SSSA meeting, November 3-6, Tampa, Florida
Conservation Priorities for Tree Crop Wild Relatives in the United StatesCWRofUS
Presentation on conservation priorities of tree crop wild relatives of the U.S., given at the Gene Conservation of Tree Species – Banking on the Future Conference, 16-19 May 2016 in Chicago, USA
The Conservation and Use of Crop Genetic Resources for Food SecurityColin Khoury
Presentation of PhD thesis, Wageningen University, Wageningen, The Netherlands, for the Hugo de Vries award by the Royal Botanical Society of the Netherlands (KNBV) for the best botany related thesis in the Netherlands in 2015, 11 April 2016, Lunteren, The Netherlands.
Conservation planning for crop wild relatives brings agricultural organizatio...CWRofUS
Our native crop wild relatives have proved useful as genetic resources in breeding better food, forage and feed, industrial, and ornamental crops. Their utilization is expected only to increase with better information on the species and improving breeding tools, but may well be constrained by their limited representation in conservation systems and the ongoing loss of wild populations due to habitat modification, invasive species, climate change and other impacts. Complementary ex situ and in situ conservation efforts for native crop genetic resources are therefore warranted, with species-specific requirements, and the necessity for education and outreach in conservation, making collaboration across conservation institutions the most prudent way forward. We present foundational information useful to collaborative efforts. An inventory of U.S. crop wild relatives has prioritized taxa related to a broad range of important crops. Utilizing occurrence data gathered from herbaria and genebanks in combination with expert inputs, resulting potential distribution models are enabling the identification of hotspots of taxonomic diversity of wild relatives in the country, and a ‘gap analysis’ methodology is facilitating efforts to identify those taxa and geographic areas of particular conservation concern. Results indicate that a broad range of wild relative diversity remains to be conserved. Numerous populations of high priority taxa could be actively managed in existing conservation areas, although many are distributed in areas without long-term habitat protection. We discuss the value of collaboration across agriculture and botanic garden organizations to better conserve our nation’s heritage of crop wild relatives.
Partnering on CWR research at three scales: commonalities for successCWR Project
The potential for crop wild relatives (CWR) to contribute to crop improvement is growing due to improvements in information on species and their diversity, advancements in breeding tools, and the growing need for exotic genetic diversity to address compounding agronomic challenges. As wild plants, CWR are subject to a myriad of human caused threats to natural ecosystems, and their representation ex situ is often far from comprehensive. Ex situ conservation of many of these wild plants is also technically challenging, particularly in an environment of insufficient resources. Enhancing conservation, availability, and access to CWR requires a spectrum of action spanning basic and applied research on wild species to inform on-the-ground collecting, ex situ maintenance, and germplasm utilization. The development of effective information channels and productive partnerships between diverse organizations are essential to the success of these actions. Here we report on a spectrum of CWR activities involving broad partnerships, at three levels: a) the collaborative compilation and distribution on over 5 million occurrence data records on the CWR of major food crops, b) the analysis of conservation concerns and genetic resources potential of the CWR of potato, sweetpotato, and pigeonpea, and c) ongoing efforts to map the diversity and conservation concerns for CWR in the USA. Although differing in scales and depth of collaborations, the success of these initiatives are largely due to commonalities in research orientation, e.g., inclusiveness, offering clear incentives for involvement, and service providing to the crop science community.
Proceedings of the 2014 Summit on Seeds & Breeds for 21st Century AgricultureRAFI-USA
To address both the growing crisis in seed biodiversity and our global capacity to develop diverse seed and breed varieties, RAFI and the Coalition for Seeds and Breeds for 21st Century Agriculture organized the 2014 Summit on Seeds and Breeds for 21st Century Agriculture.
The event, which was held in Washington, DC in March of 2014 brought together plant breeders, experts on the seed industry, farmers, activists and academics representing ten universities, twelve civil society organizations and four seed collections to discuss the state of our global seed supply and develop recommendations for reinvigorating public breeding research and increasing seed availability in the country.
The Proceedings of the 2014 Summit on Seeds & Breeds for 21st Century Agriculture provide a compilation of the summit keynote papers, response papers, presentations and findings, as well as a summary of recommendations collaboratively developed by summit participants during discussion.
The publication includes the summit keynote papers authored by well-known plant breeders and researchers in the plant breeding field including:
• William Tracy, a sweet corn breeder with the University of Wisconsin;
• Major Goodman, a corn breeder and professor of crop science at North Carolina State University;
• Tommy Carter, a research geneticist and professor of crop science at North Carolina State University;
• David Ellis, the head of the Genebank Unit at the International Potato Center in Peru;
• Kathy Jo Wetter, Research Director of ETC Group’s Action Group on Erosion, Technology & Concentration;
• Michael Mazourek, a vegetable breeder and professor of plant breeding at Cornell University; and
• Charles Brummer, Senior V.P. Director of Forage Improvement at the Samuel Roberts Noble Foundation.
Learn more: http://rafiusa.org/publications/seeds/
The indispensable bond between mazri palm (nannorrhops ritchiana) and the ind...Shujaul Mulk Khan
Keeping in mind the economic importance of this palm, the Government of Pakistan passed an act on the conservation of Nannorrhops namely “Kohat Mazri Control Act 1953” (http://kp.gov.pk/page/the-kohat -mazri -contr olact-
1953/page-type/rules ) in 1953 where laws and rules were devised for the conservation of Nannorrhops in Pakistan in general and for the Kohat Division in particular (which then
covered the whole southern Khyber Pakhtunkhwa). Regionally, it has been categorized as Endangered (EN) under the IUCN criteria. Murad et al. (2011) reported that in the Hazar
Nao Forest of Malakand Nannorrhops ritchiana is on the verge of extinction due to over exploitation by the local population for commercial purposes.
This is Rapid community assessment technique to assess the amount and distribution of crop diversity within farming communities, and widely used in various countries in on farm biodiversity management related projects.
Distributions and conservation priorities for crop wild relatives of the Unit...CWRofUS
Our native crop wild relatives have proved useful as genetic resources in breeding more productive, nutritious, and resilient crops. Their utilization is expected only to increase with better information on the species and improving breeding tools, but may well be constrained by their limited representation in seedbanks and the ongoing loss of wild populations due to habitat modification, invasive species, climate change and other impacts. Urgent collecting and habitat conservation efforts for native crop genetic resources are therefore warranted. We present foundational information needed to guide this effort. An inventory of U.S. crop wild relatives has prioritized taxa related to a broad range of important food, forage and feed, medicinal, ornamental, and industrial crops. Utilizing occurrence data gathered from herbaria and genebanks, resulting potential distribution models are enabling the identification of hotspots of taxonomic diversity of wild relatives in the country, and a ‘gap analysis’ methodology is facilitating efforts to identify those taxa and geographic areas of particular conservation concern. Results indicate that a broad range of wild relative diversity remains to be collected. Numerous populations of high priority taxa could be actively managed in existing conservation areas, although many are distributed in areas without long-term habitat protection. We discuss the value of collaboration across agriculture and natural resources management organizations to better conserve our nation’s heritage of crop wild relatives.
This is a presentation on the American Chestnut, Castanea dentata, my experiences in the last 3 field seasons while doing a census along the Appalachian Trail and other trails. Included are a definition of a native plant, non-native plants and the negative results of hybridization.
A recent project in Central Asia focused on conservation of the unique high diversity of wild and cultivated fruit species in Central Asia and enhancing farmers’ production and livelihood strategies. Read more about Bioversity International’s work in Asia Pacific Oceania
http://www.bioversityinternational.org/about-us/where-we-carry-out-research/asia-pacific-oceania/
Thanks to all the partners and funders who supported the project.
The diversity of wild edible fruit plants and traditional knowledge in west a...Adi Bejo Suwardi
Rural communities in the West Aceh region continue to collect and consume many edible wild fruit plants as a food source. This study was an account of the traditional knowledge and use of wild edible fruit plants by local people in the West Aceh region. The study was conducted in Sungai Mas and Pante Ceureumen, West Aceh Regency, between April and June 2019. Plant specimens have been gathered from the forest, agroforestry and home garden. A total of 100 informants (50 informants at each site) were involved in the survey of Ethnobotanical data. The questionnaires used to investigate the local name of the species, the habitats, the location of the collection, the season of collection, the parts used, the categories of use and the manner of fruit consumption. A total of 44 species of edible fruit plants recorded in West Aceh region, Aceh Province, Indonesia. The Myrtaceae and Malvaceae were the most represented families. Baccaurea motleyana, Durio zibethinus, Garcinia mangostana, Lansium domesticum, Mangifera odorata, and Mangifera foetida were the top six most common wild edible fruits in this region. The local community uses wild edible fruit species for food (44 species), medicine (11 species), construction materials (9 species), furniture (9 species) and firewood. D. zibethinus, M. foetida, M. odorata, M. quadrifida, B. motleyana, L. domesticum, G. xanthochymus, and G. mangostana are also commonly traded in traditional markets.
The Conservation and Use of Crop Genetic Resources for Food SecurityColin Khoury
Presentation of PhD thesis, Wageningen University, Wageningen, The Netherlands, for the Hugo de Vries award by the Royal Botanical Society of the Netherlands (KNBV) for the best botany related thesis in the Netherlands in 2015, 11 April 2016, Lunteren, The Netherlands.
Conservation planning for crop wild relatives brings agricultural organizatio...CWRofUS
Our native crop wild relatives have proved useful as genetic resources in breeding better food, forage and feed, industrial, and ornamental crops. Their utilization is expected only to increase with better information on the species and improving breeding tools, but may well be constrained by their limited representation in conservation systems and the ongoing loss of wild populations due to habitat modification, invasive species, climate change and other impacts. Complementary ex situ and in situ conservation efforts for native crop genetic resources are therefore warranted, with species-specific requirements, and the necessity for education and outreach in conservation, making collaboration across conservation institutions the most prudent way forward. We present foundational information useful to collaborative efforts. An inventory of U.S. crop wild relatives has prioritized taxa related to a broad range of important crops. Utilizing occurrence data gathered from herbaria and genebanks in combination with expert inputs, resulting potential distribution models are enabling the identification of hotspots of taxonomic diversity of wild relatives in the country, and a ‘gap analysis’ methodology is facilitating efforts to identify those taxa and geographic areas of particular conservation concern. Results indicate that a broad range of wild relative diversity remains to be conserved. Numerous populations of high priority taxa could be actively managed in existing conservation areas, although many are distributed in areas without long-term habitat protection. We discuss the value of collaboration across agriculture and botanic garden organizations to better conserve our nation’s heritage of crop wild relatives.
Partnering on CWR research at three scales: commonalities for successCWR Project
The potential for crop wild relatives (CWR) to contribute to crop improvement is growing due to improvements in information on species and their diversity, advancements in breeding tools, and the growing need for exotic genetic diversity to address compounding agronomic challenges. As wild plants, CWR are subject to a myriad of human caused threats to natural ecosystems, and their representation ex situ is often far from comprehensive. Ex situ conservation of many of these wild plants is also technically challenging, particularly in an environment of insufficient resources. Enhancing conservation, availability, and access to CWR requires a spectrum of action spanning basic and applied research on wild species to inform on-the-ground collecting, ex situ maintenance, and germplasm utilization. The development of effective information channels and productive partnerships between diverse organizations are essential to the success of these actions. Here we report on a spectrum of CWR activities involving broad partnerships, at three levels: a) the collaborative compilation and distribution on over 5 million occurrence data records on the CWR of major food crops, b) the analysis of conservation concerns and genetic resources potential of the CWR of potato, sweetpotato, and pigeonpea, and c) ongoing efforts to map the diversity and conservation concerns for CWR in the USA. Although differing in scales and depth of collaborations, the success of these initiatives are largely due to commonalities in research orientation, e.g., inclusiveness, offering clear incentives for involvement, and service providing to the crop science community.
Proceedings of the 2014 Summit on Seeds & Breeds for 21st Century AgricultureRAFI-USA
To address both the growing crisis in seed biodiversity and our global capacity to develop diverse seed and breed varieties, RAFI and the Coalition for Seeds and Breeds for 21st Century Agriculture organized the 2014 Summit on Seeds and Breeds for 21st Century Agriculture.
The event, which was held in Washington, DC in March of 2014 brought together plant breeders, experts on the seed industry, farmers, activists and academics representing ten universities, twelve civil society organizations and four seed collections to discuss the state of our global seed supply and develop recommendations for reinvigorating public breeding research and increasing seed availability in the country.
The Proceedings of the 2014 Summit on Seeds & Breeds for 21st Century Agriculture provide a compilation of the summit keynote papers, response papers, presentations and findings, as well as a summary of recommendations collaboratively developed by summit participants during discussion.
The publication includes the summit keynote papers authored by well-known plant breeders and researchers in the plant breeding field including:
• William Tracy, a sweet corn breeder with the University of Wisconsin;
• Major Goodman, a corn breeder and professor of crop science at North Carolina State University;
• Tommy Carter, a research geneticist and professor of crop science at North Carolina State University;
• David Ellis, the head of the Genebank Unit at the International Potato Center in Peru;
• Kathy Jo Wetter, Research Director of ETC Group’s Action Group on Erosion, Technology & Concentration;
• Michael Mazourek, a vegetable breeder and professor of plant breeding at Cornell University; and
• Charles Brummer, Senior V.P. Director of Forage Improvement at the Samuel Roberts Noble Foundation.
Learn more: http://rafiusa.org/publications/seeds/
The indispensable bond between mazri palm (nannorrhops ritchiana) and the ind...Shujaul Mulk Khan
Keeping in mind the economic importance of this palm, the Government of Pakistan passed an act on the conservation of Nannorrhops namely “Kohat Mazri Control Act 1953” (http://kp.gov.pk/page/the-kohat -mazri -contr olact-
1953/page-type/rules ) in 1953 where laws and rules were devised for the conservation of Nannorrhops in Pakistan in general and for the Kohat Division in particular (which then
covered the whole southern Khyber Pakhtunkhwa). Regionally, it has been categorized as Endangered (EN) under the IUCN criteria. Murad et al. (2011) reported that in the Hazar
Nao Forest of Malakand Nannorrhops ritchiana is on the verge of extinction due to over exploitation by the local population for commercial purposes.
This is Rapid community assessment technique to assess the amount and distribution of crop diversity within farming communities, and widely used in various countries in on farm biodiversity management related projects.
Distributions and conservation priorities for crop wild relatives of the Unit...CWRofUS
Our native crop wild relatives have proved useful as genetic resources in breeding more productive, nutritious, and resilient crops. Their utilization is expected only to increase with better information on the species and improving breeding tools, but may well be constrained by their limited representation in seedbanks and the ongoing loss of wild populations due to habitat modification, invasive species, climate change and other impacts. Urgent collecting and habitat conservation efforts for native crop genetic resources are therefore warranted. We present foundational information needed to guide this effort. An inventory of U.S. crop wild relatives has prioritized taxa related to a broad range of important food, forage and feed, medicinal, ornamental, and industrial crops. Utilizing occurrence data gathered from herbaria and genebanks, resulting potential distribution models are enabling the identification of hotspots of taxonomic diversity of wild relatives in the country, and a ‘gap analysis’ methodology is facilitating efforts to identify those taxa and geographic areas of particular conservation concern. Results indicate that a broad range of wild relative diversity remains to be collected. Numerous populations of high priority taxa could be actively managed in existing conservation areas, although many are distributed in areas without long-term habitat protection. We discuss the value of collaboration across agriculture and natural resources management organizations to better conserve our nation’s heritage of crop wild relatives.
This is a presentation on the American Chestnut, Castanea dentata, my experiences in the last 3 field seasons while doing a census along the Appalachian Trail and other trails. Included are a definition of a native plant, non-native plants and the negative results of hybridization.
A recent project in Central Asia focused on conservation of the unique high diversity of wild and cultivated fruit species in Central Asia and enhancing farmers’ production and livelihood strategies. Read more about Bioversity International’s work in Asia Pacific Oceania
http://www.bioversityinternational.org/about-us/where-we-carry-out-research/asia-pacific-oceania/
Thanks to all the partners and funders who supported the project.
The diversity of wild edible fruit plants and traditional knowledge in west a...Adi Bejo Suwardi
Rural communities in the West Aceh region continue to collect and consume many edible wild fruit plants as a food source. This study was an account of the traditional knowledge and use of wild edible fruit plants by local people in the West Aceh region. The study was conducted in Sungai Mas and Pante Ceureumen, West Aceh Regency, between April and June 2019. Plant specimens have been gathered from the forest, agroforestry and home garden. A total of 100 informants (50 informants at each site) were involved in the survey of Ethnobotanical data. The questionnaires used to investigate the local name of the species, the habitats, the location of the collection, the season of collection, the parts used, the categories of use and the manner of fruit consumption. A total of 44 species of edible fruit plants recorded in West Aceh region, Aceh Province, Indonesia. The Myrtaceae and Malvaceae were the most represented families. Baccaurea motleyana, Durio zibethinus, Garcinia mangostana, Lansium domesticum, Mangifera odorata, and Mangifera foetida were the top six most common wild edible fruits in this region. The local community uses wild edible fruit species for food (44 species), medicine (11 species), construction materials (9 species), furniture (9 species) and firewood. D. zibethinus, M. foetida, M. odorata, M. quadrifida, B. motleyana, L. domesticum, G. xanthochymus, and G. mangostana are also commonly traded in traditional markets.
7500 American chestnut trees and counting, the research that ate my summer in...Richard Gardner
During the summer of 2015 in reaction to the questionable concept I continually heard about the American Chestnut (Castanea dentata) going extinct I decided to do a census of the American Chestnut on the Appalachian Trail from the Rausch Gap to the Lehigh Gap and other local trails. Over 38 days were spent on the census using a GPS equipped camera with many more days gathering data on American Chestnut reproduction and how the Chestnut Blight (Cryphonectria parasitica) affected the trees. A total of over 80 miles of Appalachian Trail was walked along with at least another 40 miles on other trails. More than 7500 trees of various sizes from seedlings to mature adults were found along two trail systems separated by about 25 miles. In three separate locations a total of forty-four trees were found bearing seeds. The limiting factor in American Chestnut reproduction was clearly shown to be access to direct sunlight, not disease. The obvious conclusion derived from this time in the field is that the American Chestnut is coming back without our interference. Attempts to hybridize it with non-native chestnut species to make “blight resistant” trees are unnecessary and is detrimental to the ecology of the Appalachian forest. This study will be continued in 2016 by walking additional trails.
Presentation to Sense of Place, Palo Alto, by Miriam Sachs Martín, as Chief Preserve Steward for Acterra. Keywords: ecology, habitat, riparian, oak woodland, species, invasive, biocultural diversity, Native Americans, stewardship.
Fruits and Nuts by NK Krishna Kumar, Bioversity International, Central and So...apaari
Fruits and Nuts by NK Krishna Kumar, Bioversity International, Central and South Asia Office - Regional Expert Consultation on Underutilized Crops for Food and Nutritional Security in Asia and the Pacific November 13-15, 2017, Bangkok
Behavior of Bees Associated with the Wild Blueberry Agro-ecosystem in the USAPremier Publishers
Greenhouse and field studies were conducted between 1996 and 2014 in Maine to assess the behavior of selected bee taxa that visit wild blueberry, Vaccinium angustifolium (Ericaceae) Aiton. Some of my findings are as follows. When individual foraging efficiency was assessed on wild blueberry for four common bee pollinators, bumble bees were most efficient and honey bees were the least efficient in terms of the number of pollen grains deposited on a stigma in a single visit (P< 0.0001). However, I also found that the prior bumble bee visitation to flowers enhanced the pollination efficacy of honey bees. Field observations suggested that bumble bees recruit to plants with higher floral density and that bumble bees and andrenids forage for longer periods of time in the day than sweat bees and Osmia leaf cutting bees; honey bees showed intermediate foraging durations. Honey bees and solitary native bees were found to forage at an increasing rate with increasing air temperature, while bumble bee queens tended to forage independently of air temperature. Foraging patterns among the following bee taxa such as bumble bees, andrenids, megachilids, and honey bees also varied and the implications of these differing foraging patterns relative to pollination are discussed.
CONSERVATIONAL STUDIES ON CHLOROPHYTUM BORIVILIANUM (SAFED MUSLI) IN NANDUR...American Research Thoughts
An ethno-ecological and ethno-medicinal survey was conducted in various parts of
Nandurbar dist. of Maharashtra to find out the cause of loss of biodiversity and abundance of
Chlorophytum borivilianum. Investigation are proceeds to tracing and finding the alternative ways to
conservation of Chlorophytum borivilianumat their natural as well as to introductions as a crop in
agricultural sector due to huge ethno economic prospective.
The Road Map for North American Crop Wild Relatives: Getting to our destinationsCWRofUS
Khoury CK, Greene SL, Moreau T, Krishnan S, Miller A (2019) “The Road Map for North American Crop Wild Relatives: Getting to our destinations” Celebrating Crop Diversity: Connecting Agriculture, Public Gardens, and Science, 4 April 2019, Des Moines, USA.
Is Dormancy an Indicator of Ecotypic Variation?CWRofUS
Miller A, Sosa C, Khoury CK, Greene S. (2016). Is Dormancy an Indicator of Ecotypic Variation?” Poster for Southern Rockies Seed Network 2016 Conference, 7 December 2016, Loveland, Colorado, USA.
Partnering on crop wild relative research at three scales: commonalities for ...CWRofUS
The potential for crop wild relatives (CWR) to contribute to crop improvement is growing due to improvements in information on species and their diversity, advancements in breeding tools, and the growing need for exotic genetic diversity to address compounding agronomic challenges. As wild plants, CWR are subject to a myriad of human caused threats to natural ecosystems, and their representation ex situ is often far from comprehensive. Ex situ conservation of many of these wild plants is also technically challenging, particularly in an environment of insufficient resources. Enhancing conservation, availability, and access to CWR requires a spectrum of action spanning basic and applied research on wild species to inform on-the-ground collecting, ex situ maintenance, and germplasm utilization. The development of effective information channels and productive partnerships between diverse organizations are essential to the success of these actions. Here we report on a spectrum of CWR activities involving broad partnerships, at three levels: a) the collaborative compilation and distribution on over 5 million occurrence data records on the CWR of major food crops, b) the analysis of conservation concerns and genetic resources potential of the CWR of potato, sweetpotato, and pigeonpea, and c) ongoing efforts to map the diversity and conservation concerns for CWR in the USA. Although differing in scales and depth of collaborations, the success of these initiatives are largely due to commonalities in research orientation, e.g., inclusiveness, offering clear incentives for involvement, and service providing to the crop science community.
Presentation on progress toward a national strategy for conservation of CWR in the US, given at the curators and PGOC meeting, Spokane Washington June 2012
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Crop Wild Relatives of North America: The Way Forward for Conservation and Use
1. Crop Wild Relatives of North America:
The Ways Forward for Conservation and Use
Colin Khoury
Crop Wild Relatives of the Desert Borderlands: A Celebration of Diversity and a Call to Action
14 January 2018
University of Arizona
Tucson, AZ, USA
5. Greene et al. (eds.) (2018) North American Crop Wild Relatives, Volume 1: Conservation Strategies. Springer International Publishing AG, doi: 10.1007/978-3-319-95101-0
Greene et al. (eds.) (2019) North American Crop Wild Relatives, Volume 2: Important Species. Springer International Publishing AG, doi: 10.1007/978-3-319-97121-6
North American Crop Wild Relatives (2018, 2019)
6. Potential distributions of crop wild relatives
Marek L (2019) “Crop wild relatives of sunflower in North America” In: Greene et al. (eds.) North American Crop Wild Relatives, Volume 2: Important Species. Springer International
Publishing AG, doi: 10.1007/978-3-319-97121-6
7. Overlapping distributions of crop wild relatives
Greene et al. (2018) “Wild plant genetic resources in North America: an overview”. In: Greene et al. (eds.) North American Crop Wild Relatives, Volume 1:
Conservation Strategies. Springer International Publishing AG, doi: 10.1007/978-3-319-95101-0
8. Conservation assessments for threatened species
Pecos sunflower (Helianthus paradoxus Heiser) at Blue Hole Cienega, Santa Rosa, New Mexico. Pecos sunflower is a source of salt tolerance for cultivated
sunflower, and is listed threatened under the Endangered Species Act and globally imperiled in NatureServe (Khoury et al. 2013). Photo: Laura Marek.
13. Mount Hood National Forest, OR
Chequamegon-Nicolet National Forest, WIGifford Pinochet National Forest, WA
Monongahela National Forest, WV
Candidates for in situ reserves for wild cranberries
Photo: S. White
15. Distributions of CWR, genebanks, and botanic gardens
Moreau T and Novy A (2018) “Public Education and Outreach Opportunities for Crop Wild Relatives in North America”. In: Greene et al. (eds.) North
American Crop Wild Relatives, Volume 1: Conservation Strategies. Springer International Publishing AG, doi: 10.1007/978-3-319-95101-0
18. Moreau T and Novy A (2018) “Public Education and Outreach Opportunities for Crop Wild Relatives in North America”. In: Greene et al. (eds.) North
American Crop Wild Relatives, Volume 1: Conservation Strategies. Springer International Publishing AG, doi: 10.1007/978-3-319-95101-0
Public awareness raising about crop wild relatives
19. A Road Map for North America’s useful wild plants
1. understand and document North America’s useful
wild plants
2. collect and conserve their diversity
3. make their diversity accessible for consumption,
research, and education
4. protect threatened species in their natural habitats
5. raise public awareness of their value and the threats
to their persistence
20. Crop Wild Relatives of the Desert Borderlands: A
Celebration of Diversity and a Call to Action
January 13-15, 2019
https://www.garynabhan.com/crop-wild-relatives-of-the-desert-borderlands/
Photo: Native Seeds/SEARCH
21. Celebrating Crop Diversity:
Connecting Agriculture, Public Gardens, and Science
April 2-4, 2019
World Food Prize Foundation
Des Moines
Focus on enhancing
collaborations on crop wild
relatives and on informal food
and ag education
https://www.publicgardens.org/professional-development/2019-symposia/celebrating-crop-diversity
22. Khoury and Nabhan (2019) Conservation and Use of Crop Wild Relatives in Arizona. Southwest Center, University of
Arizona, Tucson, Arizona.
Greene et al. (2018) North American Crop Wild Relatives, Volume 1: Conservation Strategies. Springer International
Publishing AG, doi: 10.1007/978-3-319-95101-0.
Greene et al. (2018) North American Crop Wild Relatives, Volume 2: Important Species. Springer International Publishing
AG, doi: 10.1007/978-3-319-97121-6.
Khoury et al. (2013) An inventory of crop wild relatives of the United States. Crop Science 53(4): 1496.
Thank you!
Colin Khoury – c.khoury@cigar.org
Wild tepary bean (Phaseolus acutifolius A. Gray). Photo: Colin KhouryChiltepin (Capsicum annuum var. glabriusculum (Dunal) Heiser & Pickersgill).
Photo: Gary Nabhan.