Pubic lice, also known as crab lice, are small parasites typically found in the pubic area and may spread through sexual contact. Treatment options include over-the-counter medications containing permethrin or pyrethrins, as well as prescription options like lindane and malathion, although the latter is not FDA-approved for pubic lice. Proper treatment involves following instructions carefully and ensuring all sexual partners are informed and treated to prevent reinfestation.